JP7888463B2 - 不均一ハイブリッドヒドロゲル、その製造方法、および非分解性ｉｎ ｓｉｔｕフィラーインプラントとしての使用 - Google Patents

不均一ハイブリッドヒドロゲル、その製造方法、および非分解性ｉｎ ｓｉｔｕフィラーインプラントとしての使用

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Publication number
JP7888463B2
JP7888463B2 JP2022555660A JP2022555660A JP7888463B2 JP 7888463 B2 JP7888463 B2 JP 7888463B2 JP 2022555660 A JP2022555660 A JP 2022555660A JP 2022555660 A JP2022555660 A JP 2022555660A JP 7888463 B2 JP7888463 B2 JP 7888463B2
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Japan
Prior art keywords
derivatives
microbeads
methacrylamide
implant
methacryloyl
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JP2022555660A
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English (en)
Japanese (ja)
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JP2023518227A (ja
JP2023518227A5 (enExample
Inventor
ステファヌ、ウエーリー
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NeuroBioMat SAS
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NeuroBioMat SAS
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/12—Chemical modification
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00—Compositions of unspecified macromolecular compounds
    • C08L101/005—Dendritic macromolecules
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/24—Homopolymers or copolymers of amides or imides
    • C08L33/26—Homopolymers or copolymers of acrylamide or methacrylamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/622—Microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Prostheses (AREA)
  • Medicinal Preparation (AREA)
  • Graft Or Block Polymers (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
JP2022555660A 2020-03-17 2021-03-17 不均一ハイブリッドヒドロゲル、その製造方法、および非分解性ｉｎ ｓｉｔｕフィラーインプラントとしての使用 Active JP7888463B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR2002619 2020-03-17
FR2002619A FR3108260B1 (fr) 2020-03-17 2020-03-17 Hydrogel hétérogène hybride, procédé de fabrication et utilisation comme implant de comblement non-dégradable in-situ
PCT/EP2021/056753 WO2021185881A1 (fr) 2020-03-17 2021-03-17 Hydrogel hétérogène hybride, procédé de fabrication et utilisation comme implant de comblement non-dégradable in-situ

Publications (3)

Publication Number Publication Date
JP2023518227A JP2023518227A (ja) 2023-04-28
JP2023518227A5 JP2023518227A5 (enExample) 2024-03-04
JP7888463B2 true JP7888463B2 (ja) 2026-07-13

Family

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JP2022555660A Active JP7888463B2 (ja) 2020-03-17 2021-03-17 不均一ハイブリッドヒドロゲル、その製造方法、および非分解性ｉｎ ｓｉｔｕフィラーインプラントとしての使用

Country Status (12)

Country Link
US (1) US12599703B2 (enExample)
EP (1) EP4121133B1 (enExample)
JP (1) JP7888463B2 (enExample)
KR (1) KR20220154749A (enExample)
CN (1) CN115297903B (enExample)
AU (1) AU2021237753A1 (enExample)
BR (1) BR112022017583A2 (enExample)
CA (1) CA3167699A1 (enExample)
FR (1) FR3108260B1 (enExample)
IL (1) IL296328B2 (enExample)
MX (1) MX2022011096A (enExample)
WO (1) WO2021185881A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12640279B2 (en) * 2020-10-13 2026-05-26 President And Fellows Of Harvard College Viscoelastic conductive hydrogel
US20240181137A1 (en) * 2021-05-27 2024-06-06 The Regents Of The University Of California Superporous Gel Matrix for Encapsulation of Cells
CN114103125B (zh) * 2021-09-30 2022-06-28 哈尔滨工业大学（威海） 一种高导热微型器件的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010097524A1 (fr) 2009-02-24 2010-09-02 Woerly Stephane Hydrogel hétérogène hybride et son utilisation thérapeutique

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US5863551A (en) * 1996-10-16 1999-01-26 Organogel Canada Ltee Implantable polymer hydrogel for therapeutic uses
AU6100700A (en) * 1999-07-16 2001-02-05 Wesley-Jessen Corporation Thermoformable ophthalmic lens
US7163545B2 (en) 2002-07-29 2007-01-16 Mayo Foundation For Medical Education And Research Spinal cord surgical implant
NZ539713A (en) * 2002-10-11 2008-07-31 Novocell Inc Implantation of encapsulated biological materials for treating diseases
US7569222B2 (en) * 2002-11-18 2009-08-04 Woerly Stephane Hydrogel membrane composition and use thereof
US7846466B2 (en) 2004-06-10 2010-12-07 Northwestern University Biodegradable scaffolds and uses thereof
ATE464025T1 (de) * 2004-08-13 2010-04-15 Setagon Inc Herstellungsverfahren für medizinprodukte mit nanoporösen schichten
KR20140009555A (ko) 2006-04-25 2014-01-22 칠드런'즈 메디컬 센터 코포레이션 개방창 및 폐쇄창 척수 손상의 치료를 위한 방법 및 조성물
RU2394593C2 (ru) 2008-09-25 2010-07-20 Андрей Степанович БРЮХОВЕЦКИЙ Имплантируемая нейроэндопротезная система, способ ее получения и способ проведения реконструктивной нейрохирургической операции
FR2942080B1 (fr) 2009-02-09 2011-04-01 Vehicules Electr Soc D Procede de gestion thermique d'une batterie electrique
KR101091028B1 (ko) 2009-07-02 2011-12-09 아주대학교산학협력단 체내 주입형 하이드로젤 및 이의 생의학적 용도
US8877498B2 (en) 2010-12-01 2014-11-04 Drexel University Porous polymer scaffolds for neural tissue engineering and methods of producing the same
TW201313263A (zh) 2011-07-13 2013-04-01 Invivo Therapeutics Corp 聚乳酸-聚乙醇酸(plga)-b-離胺酸及plga與pll(聚e-cbz-l離胺酸)嵌段共聚物合成方法
AU2012349725B2 (en) 2011-12-06 2018-01-18 Bioarctic Neuroscience Ab Spinal cord devices and methods for promoting axonal regeneration
FR2993566B1 (fr) 2012-07-19 2015-05-15 Univ Claude Bernard Lyon Hydrogel de chitosane pour la reparation du tissu nerveux
US20150044259A1 (en) 2013-08-08 2015-02-12 Mauris N. DeSilva Scaffold for enhanced neural tissue regeneration
CN105412935B (zh) * 2015-02-04 2019-02-19 四川大学 一种基于n-(2-羟丙基)甲基丙烯酰胺聚合物的纳米粒及其制备方法
US20180037865A1 (en) 2016-08-05 2018-02-08 Wayne State University Methods and compositions relating to treatment of nervous system injuries
JP2024545175A (ja) * 2021-12-09 2024-12-05 リカルダ、インコーポレイテッド ヒドロゲルマイクロ粒子ベースの軟組織充填剤

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WO2010097524A1 (fr) 2009-02-24 2010-09-02 Woerly Stephane Hydrogel hétérogène hybride et son utilisation thérapeutique

Also Published As

Publication number Publication date
EP4121133A1 (fr) 2023-01-25
MX2022011096A (es) 2022-11-10
CA3167699A1 (en) 2021-09-23
BR112022017583A2 (pt) 2022-10-18
IL296328A (en) 2022-11-01
FR3108260A1 (fr) 2021-09-24
CN115297903A (zh) 2022-11-04
IL296328B1 (en) 2025-11-01
IL296328B2 (en) 2026-03-01
KR20220154749A (ko) 2022-11-22
EP4121133B1 (fr) 2023-08-16
JP2023518227A (ja) 2023-04-28
US12599703B2 (en) 2026-04-14
CN115297903B (zh) 2024-03-12
EP4121133C0 (fr) 2023-08-16
FR3108260B1 (fr) 2024-01-05
US20230166005A1 (en) 2023-06-01
WO2021185881A1 (fr) 2021-09-23
AU2021237753A1 (en) 2022-10-20

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