JP7884454B2 - 免疫調節分子を発現する細胞および免疫調節分子を発現するための系 - Google Patents

免疫調節分子を発現する細胞および免疫調節分子を発現するための系

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JP7884454B2
JP7884454B2 JP2022539336A JP2022539336A JP7884454B2 JP 7884454 B2 JP7884454 B2 JP 7884454B2 JP 2022539336 A JP2022539336 A JP 2022539336A JP 2022539336 A JP2022539336 A JP 2022539336A JP 7884454 B2 JP7884454 B2 JP 7884454B2
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cells
cell
domain
immune
polypeptide
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JP2023515747A (ja
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チェン，チジュン
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シャンハイ セル セラピー グループ カンパニー カンパニー リミテッド
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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JP2022539336A 2019-12-28 2020-12-28 免疫調節分子を発現する細胞および免疫調節分子を発現するための系 Active JP7884454B2 (ja)

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US201962954448P 2019-12-28 2019-12-28
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PCT/IB2020/001079 WO2021130535A2 (en) 2019-12-28 2020-12-28 Cell expressing immune modulatory molecules and system for expressing immune modulatory molecules

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CN119874940A (zh) * 2021-12-29 2025-04-25 上海细胞治疗集团股份有限公司 抗间皮素纳米抗体嵌合抗原受体及其应用
CN118206620A (zh) * 2022-12-09 2024-06-18 上海细胞治疗集团股份有限公司 一种多肽标签及其应用
CN119269786A (zh) * 2023-06-29 2025-01-07 上海细胞治疗集团股份有限公司 一种评估car产生细胞免疫应答的方法
WO2025209437A1 (zh) * 2024-04-02 2025-10-09 原启生物科技(上海)有限责任公司 经修饰的免疫细胞及其用途
WO2026152120A2 (en) 2025-01-13 2026-07-16 HCW Biologics, Inc. Chimeric polypeptides and uses thereof

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