JP7822308B2 - 固形腫瘍の処置のための組成物 - Google Patents

固形腫瘍の処置のための組成物

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Publication number
JP7822308B2
JP7822308B2 JP2022515083A JP2022515083A JP7822308B2 JP 7822308 B2 JP7822308 B2 JP 7822308B2 JP 2022515083 A JP2022515083 A JP 2022515083A JP 2022515083 A JP2022515083 A JP 2022515083A JP 7822308 B2 JP7822308 B2 JP 7822308B2
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pharmaceutical composition
weight
acid
compound
formula
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JP2022515083A
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Japanese (ja)
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JP2023503769A (ja
JP2023503769A5 (https=
Inventor
ブルメンフェルド，アロン
ゲータ，ラケーリ
ブローグランド，エラン
Original Assignee
ラジエル セラピューティクス エルティーディー．
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2022515083A 2019-09-15 2020-09-14 固形腫瘍の処置のための組成物 Active JP7822308B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962900557P 2019-09-15 2019-09-15
PCT/IB2020/000745 WO2021048626A1 (en) 2019-09-15 2020-09-14 Compositions for the treatment of solid tumors

Publications (3)

Publication Number Publication Date
JP2023503769A JP2023503769A (ja) 2023-02-01
JP2023503769A5 JP2023503769A5 (https=) 2023-09-04
JP7822308B2 true JP7822308B2 (ja) 2026-03-02

Family

ID=74866186

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022515083A Active JP7822308B2 (ja) 2019-09-15 2020-09-14 固形腫瘍の処置のための組成物

Country Status (7)

Country Link
US (1) US20220323411A1 (https=)
EP (1) EP4031130A4 (https=)
JP (1) JP7822308B2 (https=)
CN (1) CN115066241A (https=)
AU (1) AU2020347539A1 (https=)
IL (1) IL291351A (https=)
WO (1) WO2021048626A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3307323B1 (en) 2015-06-15 2022-07-13 Raziel Therapeutics Ltd. Carbazole derivatives for the treatment of fibrotic diseases and related symptoms, and conditions thereof
EP4334286A4 (en) * 2021-05-06 2025-03-19 Raziel Therapeutics Ltd. CRYSTALLINE CARBAZOLE DERIVATIVE
CN120693158A (zh) * 2022-11-07 2025-09-23 拉结尔治疗有限公司 结晶咔唑衍生物及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012504659A (ja) 2008-10-06 2012-02-23 インクロン， リミテッド ライアビリティー カンパニー カルバゾール化合物および当該化合物の治療用途
JP2014533264A (ja) 2011-11-15 2014-12-11 イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム リミテッド 三環式化合物、それらを含む組成物およびそれらの使用
JP2023510865A (ja) 2020-01-28 2023-03-15 ラジエル セラピューティクス エルティーディー． 血管脂肪腫の処置のための組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0311406D0 (en) * 2003-05-17 2003-06-25 Queen Mary & Westfield College Substituted phosphonate fluorescent sensors,and use thereof
EP3307323B1 (en) * 2015-06-15 2022-07-13 Raziel Therapeutics Ltd. Carbazole derivatives for the treatment of fibrotic diseases and related symptoms, and conditions thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012504659A (ja) 2008-10-06 2012-02-23 インクロン， リミテッド ライアビリティー カンパニー カルバゾール化合物および当該化合物の治療用途
JP2014533264A (ja) 2011-11-15 2014-12-11 イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム リミテッド 三環式化合物、それらを含む組成物およびそれらの使用
JP2023510865A (ja) 2020-01-28 2023-03-15 ラジエル セラピューティクス エルティーディー． 血管脂肪腫の処置のための組成物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ChemMedChem，2018年，Vol. 13，pp. 2635-2643，DOI: 10.1002/cmdc.201800546

Also Published As

Publication number Publication date
EP4031130A1 (en) 2022-07-27
AU2020347539A1 (en) 2022-03-31
CN115066241A (zh) 2022-09-16
JP2023503769A (ja) 2023-02-01
IL291351A (en) 2022-05-01
EP4031130A4 (en) 2023-10-11
WO2021048626A1 (en) 2021-03-18
US20220323411A1 (en) 2022-10-13

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