JP7755772B2 - 化合物又はその塩及びその製造方法、組成物、過酸化水素除去剤、並びに、細胞毒性抑制剤 - Google Patents
化合物又はその塩及びその製造方法、組成物、過酸化水素除去剤、並びに、細胞毒性抑制剤Info
- Publication number
- JP7755772B2 JP7755772B2 JP2025519185A JP2025519185A JP7755772B2 JP 7755772 B2 JP7755772 B2 JP 7755772B2 JP 2025519185 A JP2025519185 A JP 2025519185A JP 2025519185 A JP2025519185 A JP 2025519185A JP 7755772 B2 JP7755772 B2 JP 7755772B2
- Authority
- JP
- Japan
- Prior art keywords
- mass
- less
- compound
- hydrogen peroxide
- cytotoxicity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023098209 | 2023-06-15 | ||
| JP2023098209 | 2023-06-15 | ||
| PCT/JP2024/021265 WO2024257775A1 (ja) | 2023-06-15 | 2024-06-12 | 化合物又はその塩及びその製造方法、組成物、過酸化水素除去剤、並びに、細胞毒性抑制剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2024257775A1 JPWO2024257775A1 (https=) | 2024-12-19 |
| JPWO2024257775A5 JPWO2024257775A5 (https=) | 2025-06-12 |
| JP7755772B2 true JP7755772B2 (ja) | 2025-10-16 |
Family
ID=93852144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025519185A Active JP7755772B2 (ja) | 2023-06-15 | 2024-06-12 | 化合物又はその塩及びその製造方法、組成物、過酸化水素除去剤、並びに、細胞毒性抑制剤 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP4729511A1 (https=) |
| JP (1) | JP7755772B2 (https=) |
| KR (1) | KR20260022421A (https=) |
| CN (1) | CN121311472A (https=) |
| WO (1) | WO2024257775A1 (https=) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007300916A (ja) | 2006-04-10 | 2007-11-22 | Manabu Nukina | エルゴチオネインの製造方法 |
| CN109091422A (zh) | 2018-08-01 | 2018-12-28 | 上海应用技术大学 | 含榆黄菇提取液的化妆品及其制备方法 |
| CN109293572A (zh) | 2018-09-26 | 2019-02-01 | 上海市农业科学院 | 一种提取榆黄菇中麦角硫因与多糖的方法 |
| WO2021177397A1 (ja) | 2020-03-04 | 2021-09-10 | 長瀬産業株式会社 | L-エルゴチオネイン含有組成物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008156320A (ja) | 2006-12-26 | 2008-07-10 | Hydrox Kk | 抗酸化性機能水 |
| JP2020103100A (ja) | 2018-12-27 | 2020-07-09 | 小林製薬株式会社 | 細胞内の抗酸化機能亢進剤 |
-
2024
- 2024-06-12 CN CN202480039105.XA patent/CN121311472A/zh active Pending
- 2024-06-12 JP JP2025519185A patent/JP7755772B2/ja active Active
- 2024-06-12 KR KR1020267000808A patent/KR20260022421A/ko active Pending
- 2024-06-12 EP EP24823390.0A patent/EP4729511A1/en active Pending
- 2024-06-12 WO PCT/JP2024/021265 patent/WO2024257775A1/ja not_active Ceased
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007300916A (ja) | 2006-04-10 | 2007-11-22 | Manabu Nukina | エルゴチオネインの製造方法 |
| CN109091422A (zh) | 2018-08-01 | 2018-12-28 | 上海应用技术大学 | 含榆黄菇提取液的化妆品及其制备方法 |
| CN109293572A (zh) | 2018-09-26 | 2019-02-01 | 上海市农业科学院 | 一种提取榆黄菇中麦角硫因与多糖的方法 |
| WO2021177397A1 (ja) | 2020-03-04 | 2021-09-10 | 長瀬産業株式会社 | L-エルゴチオネイン含有組成物 |
Non-Patent Citations (1)
| Title |
|---|
| SERVILLO, L. et al.,An uncommon redox behavior sheds light on the cellular antioxidant properties of ergothioneine,Free Radical Biology & Medicine,2015年,79,pp. 228-236,DOI: 10.1016/j.freeradbiomed.2014.11.017 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2024257775A1 (ja) | 2024-12-19 |
| EP4729511A1 (en) | 2026-04-22 |
| JPWO2024257775A1 (https=) | 2024-12-19 |
| KR20260022421A (ko) | 2026-02-19 |
| CN121311472A (zh) | 2026-01-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Zhang et al. | Discovery of potent epidermal growth factor receptor (EGFR) degraders by proteolysis targeting chimera (PROTAC) | |
| US8143069B2 (en) | Fluorescent probe and method of measuring hypochlorite ion | |
| EP3380457B1 (en) | Monosulfonic phenyltetrazole compounds with applications | |
| JP7450559B2 (ja) | 疾患の処置のためのkdm1a阻害剤 | |
| ES2605564T3 (es) | Sal farmacéuticamente aceptable de (E)-N-[4-[[3-cloro-4-(2-piridilmetoxi)fenil]amino]-3-ciano-7-etoxi-6-quinolil]-3-[(2R)-1-metilpirrolidin-2-il]prop-2-enamida, método de preparación para la misma, y uso médico de la misma | |
| NO20071521L (no) | Nye fenylaminopyrimidin derivater som hemmere av BCR-ABL kinase | |
| JP7359439B2 (ja) | ニコチンアミドn-メチルトランスフェラーゼ(nnmt)のキノリン由来小分子阻害剤及びその使用 | |
| ATE457981T1 (de) | 3-amido-1,2-benzisoxazolderivate, herstellungsverfahren und deren verwendung | |
| KR101282833B1 (ko) | 신규한 히스톤 디아세틸라제 저해제로서의 치환된프로페닐피페라진 유도체 | |
| EP4172159A1 (en) | Compositions and methods for modulating hair growth | |
| DE602004005960D1 (de) | Heteroaryl-substituierte pyrrolä2, 3- büpyridin-derivate als crf-rezeptor-antagonisten | |
| WO2017017048A1 (en) | Analogs of adamantylureas as soluble epoxide hydrolase inhibitors | |
| Adhikari et al. | Colorimetric and fluorescence probe for the detection of nano-molar lysine in aqueous medium | |
| Missbach et al. | Substituted 5, 7-diphenyl-pyrrolo [2, 3d] pyrimidines: potent inhibitors of the tyrosine kinase c-Src | |
| JP7755772B2 (ja) | 化合物又はその塩及びその製造方法、組成物、過酸化水素除去剤、並びに、細胞毒性抑制剤 | |
| MA29943B1 (fr) | Derives de pyrazolo[4,3-d] pyrimidine-5-yle utilises comme inhibiteurs de pde5 | |
| MXPA06000986A (es) | Compuestos. | |
| Ino et al. | Characterization of inhibitor binding sites of mitochondrial complex I using fluorescent inhibitor | |
| WO2007073303A3 (en) | Novel benzimidazole derivatives as vanilloid receptor 1 (vrl) inhibitors | |
| Fantacuzzi et al. | Screening of NOS activity and selectivity of newly synthesized acetamidines using RP-HPLC | |
| CR20250409A (es) | Derivados de oxazolo[4,5-b]pirazina y oxazolo[4,5-b]piridina como inhibidores de nlpr3 para el tratamiento de, por ejemplo, enfermedades inflamatoria | |
| Detremmerie et al. | Endothelium-dependent contractions of isolated arteries to thymoquinone require biased activity of soluble guanylyl cyclase with subsequent cyclic IMP production | |
| EP1553409A1 (en) | Reagents for the measurement of peroxynitrites | |
| ATE462703T1 (de) | Bicyclononen-derivate als renin-inhibitoren | |
| MX2024012970A (es) | Inhibidores de la 17-beta-hidroxiesteroide deshidrogenasa tipo 13 que contienen pirimidinona |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20250402 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20250402 |
|
| A871 | Explanation of circumstances concerning accelerated examination |
Free format text: JAPANESE INTERMEDIATE CODE: A871 Effective date: 20250402 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20250624 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20250825 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20250911 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20251002 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20251003 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 7755772 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |