JP7731075B2 - アレルゲンの不活化方法及びアレルゲン不活化装置 - Google Patents

アレルゲンの不活化方法及びアレルゲン不活化装置

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Publication number
JP7731075B2
JP7731075B2 JP2022532511A JP2022532511A JP7731075B2 JP 7731075 B2 JP7731075 B2 JP 7731075B2 JP 2022532511 A JP2022532511 A JP 2022532511A JP 2022532511 A JP2022532511 A JP 2022532511A JP 7731075 B2 JP7731075 B2 JP 7731075B2
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Prior art keywords
redox
allergen
protein
electrode
electrons
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Japanese (ja)
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JPWO2021261511A1 (https=
JPWO2021261511A5 (https=
Inventor
紀幸 初谷
泰章 奥村
文哉 和山
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Panasonic Intellectual Property Management Co Ltd
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Panasonic Intellectual Property Management Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/14—Enzymes or microbial cells immobilised on or in an inorganic carrier
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0051—Oxidoreductases (1.) acting on a sulfur group of donors (1.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y108/00—Oxidoreductases acting on sulfur groups as donors (1.8)
    • C12Y108/01—Oxidoreductases acting on sulfur groups as donors (1.8) with NAD+ or NADP+ as acceptor (1.8.1)
    • C12Y108/01007—Glutathione-disulfide reductase (1.8.1.7), i.e. glutathione reductase (NADPH)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y108/00—Oxidoreductases acting on sulfur groups as donors (1.8)
    • C12Y108/01—Oxidoreductases acting on sulfur groups as donors (1.8) with NAD+ or NADP+ as acceptor (1.8.1)
    • C12Y108/01008—Protein-disulfide reductase (1.8.1.8), i.e. thioredoxin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y108/00—Oxidoreductases acting on sulfur groups as donors (1.8)
    • C12Y108/01—Oxidoreductases acting on sulfur groups as donors (1.8) with NAD+ or NADP+ as acceptor (1.8.1)
    • C12Y108/01009—Thioredoxin-disulfide reductase (1.8.1.9), i.e. thioredoxin-reductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y108/00—Oxidoreductases acting on sulfur groups as donors (1.8)
    • C12Y108/07—Oxidoreductases acting on sulfur groups as donors (1.8) with an iron-sulfur protein as acceptor (1.8.7)
    • C12Y108/07002—Ferredoxin:thioredoxin reductase (1.8.7.2)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2022532511A 2020-06-23 2021-06-23 アレルゲンの不活化方法及びアレルゲン不活化装置 Active JP7731075B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2020108223 2020-06-23
JP2020108223 2020-06-23
JP2021003786 2021-01-13
JP2021003786 2021-01-13
PCT/JP2021/023754 WO2021261511A1 (ja) 2020-06-23 2021-06-23 アレルゲンの不活化方法及びアレルゲン不活化装置

Publications (3)

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JPWO2021261511A1 JPWO2021261511A1 (https=) 2021-12-30
JPWO2021261511A5 JPWO2021261511A5 (https=) 2023-03-28
JP7731075B2 true JP7731075B2 (ja) 2025-08-29

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US (1) US20230119996A1 (https=)
EP (1) EP4169933A4 (https=)
JP (1) JP7731075B2 (https=)
CN (1) CN115768865A (https=)
AU (1) AU2021298391A1 (https=)
CA (1) CA3187826A1 (https=)
WO (1) WO2021261511A1 (https=)

Families Citing this family (6)

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Publication number Priority date Publication date Assignee Title
JPWO2022270588A1 (https=) * 2021-06-23 2022-12-29
EP4549623A4 (en) * 2022-06-30 2025-10-22 Panasonic Ip Man Co Ltd METHOD FOR REDUCING TARGET MOLECULE, REDUCTION DEVICE AND ELECTRODE
EP4563699A4 (en) * 2022-07-26 2025-11-26 Panasonic Ip Man Co Ltd ENZYMATIC ELECTRODE, ENZYMATIC REACTION DEVICE, ENZYMATIC REACTION METHOD, MODIFIED PROTEIN AND METHOD FOR PRODUCING MODIFIED PROTEIN
EP4563698A1 (en) * 2022-07-26 2025-06-04 Panasonic Intellectual Property Management Co., Ltd. Enzyme electrode, reduction device, reduction method, modified protein, and production method for modified protein
WO2024142963A1 (ja) * 2022-12-27 2024-07-04 パナソニックＩｐマネジメント株式会社 食品成分変換方法、および食品成分変換装置
WO2024157666A1 (ja) * 2023-01-26 2024-08-02 パナソニックＩｐマネジメント株式会社 食品成分変換方法、および食品成分変換装置

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001520027A (ja) 1997-10-17 2001-10-30 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア チオレドキシン還元による食物蛋白質の消化性向上
JP2009002689A (ja) 2007-06-19 2009-01-08 Canon Inc チオレドキシン類測定用電極、チオレドキシン類の測定方法、チオレドキシン類の測定装置
WO2010097619A1 (en) 2009-02-25 2010-09-02 The University Of Hull Immobilized enzymes and co-factors
CN109652402A (zh) 2019-01-18 2019-04-19 浙江工业大学 基于电化学的辅酶还原型谷胱甘肽再生方法及酶电极

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0672127B1 (en) * 1991-10-12 1999-01-07 The Regents Of The University Of California Use of thiol redox proteins for reducing disulfide bonds
US5792506A (en) * 1991-10-12 1998-08-11 The Regents Of The University Of California Neutralization of food allergens by thioredoxin
US6677433B2 (en) * 1999-01-27 2004-01-13 The Regents Of The University Of California Stabilization of hypoallergenic, hyperdigestible previously reduced proteins
EP2172767A1 (en) * 2008-10-06 2010-04-07 Sony Corporation A sensor for thiol analytes
JP6127799B2 (ja) 2013-07-23 2017-05-17 三菱電機株式会社 超電導コイルの駆動システム
EP3523640B1 (en) * 2016-10-05 2023-01-18 Abbott Laboratories Devices for sample analysis
WO2019006413A1 (en) * 2017-06-30 2019-01-03 Abbott Diabetes Care METHOD AND APPARATUS FOR ANALYTE DETECTION USING ELECTROCHEMICAL BIOSENSOR
WO2021138682A1 (en) * 2020-01-03 2021-07-08 Orpro Therapeutics, Inc. Compositions having thioredoxin activity and related methods

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001520027A (ja) 1997-10-17 2001-10-30 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア チオレドキシン還元による食物蛋白質の消化性向上
JP2009002689A (ja) 2007-06-19 2009-01-08 Canon Inc チオレドキシン類測定用電極、チオレドキシン類の測定方法、チオレドキシン類の測定装置
WO2010097619A1 (en) 2009-02-25 2010-09-02 The University Of Hull Immobilized enzymes and co-factors
CN109652402A (zh) 2019-01-18 2019-04-19 浙江工业大学 基于电化学的辅酶还原型谷胱甘肽再生方法及酶电极

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Publication number Publication date
JPWO2021261511A1 (https=) 2021-12-30
AU2021298391A1 (en) 2023-02-02
CA3187826A1 (en) 2021-12-30
AU2021298391A2 (en) 2023-03-09
CN115768865A (zh) 2023-03-07
EP4169933A4 (en) 2023-12-27
EP4169933A1 (en) 2023-04-26
WO2021261511A1 (ja) 2021-12-30
US20230119996A1 (en) 2023-04-20

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