JP7716111B2 - 神経変性疾患の症状の緩和又は治療のための貼付剤 - Google Patents

神経変性疾患の症状の緩和又は治療のための貼付剤

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Publication number
JP7716111B2
JP7716111B2 JP2022545757A JP2022545757A JP7716111B2 JP 7716111 B2 JP7716111 B2 JP 7716111B2 JP 2022545757 A JP2022545757 A JP 2022545757A JP 2022545757 A JP2022545757 A JP 2022545757A JP 7716111 B2 JP7716111 B2 JP 7716111B2
Authority
JP
Japan
Prior art keywords
scopolamine
patch
administration
hours
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2022545757A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2022045335A1 (https=
Inventor
孝行 小川
健太 西村
洋明 上野
悠平 谷
美恵子 荻野
公紀 佐藤
久典 廿日岩
勝則 三好
貴博 井上
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nobelpharma Co Ltd
Original Assignee
Nobelpharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nobelpharma Co Ltd filed Critical Nobelpharma Co Ltd
Publication of JPWO2022045335A1 publication Critical patent/JPWO2022045335A1/ja
Application granted granted Critical
Publication of JP7716111B2 publication Critical patent/JP7716111B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2022545757A 2020-08-31 2021-08-30 神経変性疾患の症状の緩和又は治療のための貼付剤 Active JP7716111B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020145562 2020-08-31
JP2020145562 2020-08-31
PCT/JP2021/031712 WO2022045335A1 (ja) 2020-08-31 2021-08-30 神経変性疾患の症状の緩和又は治療のための貼付剤

Publications (2)

Publication Number Publication Date
JPWO2022045335A1 JPWO2022045335A1 (https=) 2022-03-03
JP7716111B2 true JP7716111B2 (ja) 2025-07-31

Family

ID=80353475

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022545757A Active JP7716111B2 (ja) 2020-08-31 2021-08-30 神経変性疾患の症状の緩和又は治療のための貼付剤

Country Status (8)

Country Link
US (1) US20230293510A1 (https=)
EP (1) EP4205744A4 (https=)
JP (1) JP7716111B2 (https=)
CN (1) CN115989025A (https=)
AU (1) AU2021331298A1 (https=)
CA (1) CA3193154A1 (https=)
TW (1) TW202228688A (https=)
WO (1) WO2022045335A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114848613A (zh) * 2022-05-09 2022-08-05 山东中医药大学 一种东莨菪碱可溶性微针贴片及其制备方法和应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006516267A (ja) 2003-01-17 2006-06-29 エルテーエス ローマン テラピー−ジステーメ アーゲー コリンエステラーゼ阻害剤中毒の医薬的予防方法並びにこれに適する活性物質および医薬
CN1994307A (zh) 2006-12-12 2007-07-11 中国人民解放军第二军医大学 一种预防有机磷酸酯类化合物中毒的复方经皮给药制剂
JP2015083569A (ja) 2008-05-30 2015-04-30 マイラン・インコーポレーテッド 安定化された経皮薬物送達システム
JP2020525546A (ja) 2017-06-26 2020-08-27 エルテーエス ローマン テラピー−ジステーメ アーゲー スコポラミン及びシリコーンアクリルハイブリッドポリマーを含有する経皮治療システム

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7150881B2 (en) * 1997-06-26 2006-12-19 Mylan Technologies, Inc. Adhesive mixture for transdermal delivery of highly plasticizing drugs
US20070010550A1 (en) * 2005-07-08 2007-01-11 The Board Of Regents Of The University Of Texas Scopolamine to Reduce or Eliminate Hot Flashes, Night Sweats, and Insomnia
US20080090808A1 (en) * 2006-10-17 2008-04-17 Franklin Volvovitz Pharmaceutical compositions and methods for preventing, treating, or reversing neuronal dysfunction
US20220160697A1 (en) * 2019-03-19 2022-05-26 Nobelpharma Co., Ltd. Pharmaceutical composition having excellent drug absorption into the living body and excellent chemical stability

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006516267A (ja) 2003-01-17 2006-06-29 エルテーエス ローマン テラピー−ジステーメ アーゲー コリンエステラーゼ阻害剤中毒の医薬的予防方法並びにこれに適する活性物質および医薬
CN1994307A (zh) 2006-12-12 2007-07-11 中国人民解放军第二军医大学 一种预防有机磷酸酯类化合物中毒的复方经皮给药制剂
JP2015083569A (ja) 2008-05-30 2015-04-30 マイラン・インコーポレーテッド 安定化された経皮薬物送達システム
JP2020525546A (ja) 2017-06-26 2020-08-27 エルテーエス ローマン テラピー−ジステーメ アーゲー スコポラミン及びシリコーンアクリルハイブリッドポリマーを含有する経皮治療システム

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MONTERO,M.A, et al.，Control of drooling using transdermal scopolamine skin patches. A case report，Med Oral Patol Oral Cir Bucal，2008年，Vol.13.No.1，pp.E27-E30
MORISE,B.T. et al.，Scopolamine loaded in natural rubber latex as a future transdermal patch for sialorrhea treatment，International Journal of Plolymeric Materials and Polymeric Biomaterials，2019年，Vol.68, No.13，pp.788-795
Otolaryngology-Head and Neck Surgery，1990年，Vol.103, No.4，pp.615-618

Also Published As

Publication number Publication date
EP4205744A4 (en) 2024-09-11
EP4205744A1 (en) 2023-07-05
AU2021331298A1 (en) 2023-03-23
CA3193154A1 (en) 2022-03-03
CN115989025A (zh) 2023-04-18
US20230293510A1 (en) 2023-09-21
WO2022045335A1 (ja) 2022-03-03
JPWO2022045335A1 (https=) 2022-03-03
TW202228688A (zh) 2022-08-01

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