JP7702150B2 - Stat3のリン酸化抑制剤、自己免疫疾患及びコロナウイルス感染症の予防又は治療剤 - Google Patents

Stat3のリン酸化抑制剤、自己免疫疾患及びコロナウイルス感染症の予防又は治療剤 Download PDF

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JP7702150B2
JP7702150B2 JP2022533676A JP2022533676A JP7702150B2 JP 7702150 B2 JP7702150 B2 JP 7702150B2 JP 2022533676 A JP2022533676 A JP 2022533676A JP 2022533676 A JP2022533676 A JP 2022533676A JP 7702150 B2 JP7702150 B2 JP 7702150B2
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眞也 大河内
雅彦 兼平
克典 岡田
一 黒澤
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Tohoku University NUC
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Gastroenterology & Hepatology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
JP2022533676A 2020-06-30 2021-03-01 Stat3のリン酸化抑制剤、自己免疫疾患及びコロナウイルス感染症の予防又は治療剤 Active JP7702150B2 (ja)

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JP2025085915A JP2025109968A (ja) 2020-06-30 2025-05-22 Stat3のリン酸化抑制剤、自己免疫疾患及びコロナウイルス感染症の予防又は治療剤

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JP2020112680 2020-06-30
JP2020112680 2020-06-30
PCT/JP2021/007780 WO2022004054A1 (ja) 2020-06-30 2021-03-01 Stat3のリン酸化抑制剤、自己免疫疾患及びコロナウイルス感染症の予防又は治療剤

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JP7702150B2 true JP7702150B2 (ja) 2025-07-03

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JP2025085915A Pending JP2025109968A (ja) 2020-06-30 2025-05-22 Stat3のリン酸化抑制剤、自己免疫疾患及びコロナウイルス感染症の予防又は治療剤

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US (1) US20230201310A1 (https=)
EP (1) EP4194004A4 (https=)
JP (2) JP7702150B2 (https=)
CN (1) CN115835879A (https=)
WO (1) WO2022004054A1 (https=)

Families Citing this family (1)

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Publication number Priority date Publication date Assignee Title
CN114732831B (zh) * 2022-04-25 2023-06-23 齐鲁理工学院 斯钙素-1作为调节肿瘤微环境的标志物的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013008681A1 (ja) 2011-07-09 2013-01-17 国立大学法人東北大学 線維症予防又は治療用医薬組成物
JP2016520583A (ja) 2013-05-10 2016-07-14 オルフス ユニバーシテト パッパリシンレギュレーター

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2387685A1 (en) * 1999-10-27 2001-05-03 Human Genome Sciences, Inc. Stanniocalcin proteins and nucleic acids and methods based thereon
US8759298B2 (en) * 2010-05-03 2014-06-24 Scott & White Healthcare Protein therapy for corneal inflammation, epithelial wound healing, and photoreceptor degeneration

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013008681A1 (ja) 2011-07-09 2013-01-17 国立大学法人東北大学 線維症予防又は治療用医薬組成物
JP2016520583A (ja) 2013-05-10 2016-07-14 オルフス ユニバーシテト パッパリシンレギュレーター

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
BONFANTE, S. et al., Stanniocalcin 1 Inhibits the Inflammatory Response in Microglia and Protects Against Sepsis-Associa,Neurotoxicity Research,2020年10月06日,Vol. 39,pp. 119-132
Cytokine: X,2020年05月14日,Vol. 2, No. 2, 100029,pp. 1-7,DOI: 10.1016/j.cytox.2020.100029
Free Radical Biology and Medicine,2014年,Vol. 71,pp. 321-331,DOI: 10.1016/j.freeradbiomed.2014.03.034
HUANG, L. et al.,Stanniocalcin-1 inhibits thrombin-induced signaling and protects from bleomycin-induced lung injury,SCIENTIFIC REPORTS,2015年,Vol. 5,article number 18117, pp. 1-13
Innovative Medicine,2015年,pp. 131-147,DOI: 10.1007/978-4-431-55651-0_11
WU, Y. et al.,Upregulation of stanniocalcin‐1 inhibits the development of osteoarthritis by inhibiting survival a,Journal of Cellular Biochemistry,2019年,Vol. 120,pp. 9768-9780,DOI: 10.1002/jcb.28257
ZHAO, J. et al.,Stanniocalcin 2 Ameliorates Hepatosteatosis Through Activation of STAT3 Signaling,Frontiers in Physiology,2018年,Vol. 9, Article 873,pp. 1-8
ウイルス,Vol. 69, No. 1,2019年,pp. 61-72,<URL: http://jsv.umin.jp/journal/v69-1pdf/virus69-1_061-072.pdf>

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US20230201310A1 (en) 2023-06-29
JP2025109968A (ja) 2025-07-25
CN115835879A (zh) 2023-03-21
EP4194004A1 (en) 2023-06-14
WO2022004054A1 (ja) 2022-01-06
TW202207972A (zh) 2022-03-01
JPWO2022004054A1 (https=) 2022-01-06
EP4194004A4 (en) 2024-07-24

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