JP7677908B2 - 抗bcma免疫療法によりがんを処置するための組成物および方法 - Google Patents

抗bcma免疫療法によりがんを処置するための組成物および方法 Download PDF

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JP7677908B2
JP7677908B2 JP2021571004A JP2021571004A JP7677908B2 JP 7677908 B2 JP7677908 B2 JP 7677908B2 JP 2021571004 A JP2021571004 A JP 2021571004A JP 2021571004 A JP2021571004 A JP 2021571004A JP 7677908 B2 JP7677908 B2 JP 7677908B2
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car
cells
domain
antigen
bcma
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JP2022535005A5 (enExample
JP2022535005A (ja
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シュナイダー,ディナ
チュー,ゾンユイ
ドロプリク,ボロ
ブー,バン・コア
アラバンザ,リア・マリー
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Lentigen Technology Inc
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/41—Vertebrate antigens
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    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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JP2021571004A 2019-05-30 2020-05-29 抗bcma免疫療法によりがんを処置するための組成物および方法 Active JP7677908B2 (ja)

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US201962854574P 2019-05-30 2019-05-30
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PCT/US2020/035287 WO2020243546A1 (en) 2019-05-30 2020-05-29 Compositions and methods for treating cancer with anti-bcma immunotherapy

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CA3140102A1 (en) 2019-05-30 2020-12-03 Dina SCHNEIDER Compositions and methods for treating cancer with anti-bcma immunotherapy
CN114149505B (zh) * 2021-01-12 2022-11-04 北京门罗生物科技有限公司 治疗b细胞相关疾病的免疫细胞、制备方法及其应用
CN119923410A (zh) 2022-07-28 2025-05-02 莱蒂恩技术公司 用于治疗实体瘤的嵌合抗原受体治疗
WO2024044743A1 (en) 2022-08-26 2024-02-29 Lentigen Technology, Inc. Compositions and methods for treating cancer with fully human anti-cd20/cd19 immunotherapy
WO2025171388A1 (en) 2024-02-09 2025-08-14 Dispatch Biotherapeutics, Inc. Engineered cancer antigens with modified domains and related methods and uses
WO2025171383A2 (en) 2024-02-09 2025-08-14 Dispatch Biotherapeutics, Inc. Engineered cancer antigens and related methods and uses
US20260000765A1 (en) 2024-06-27 2026-01-01 Lentigen Technology, Inc. CHIMERIC ANTIGEN RECEPTOR THERAPIES FOR TREATING CANCER WITH IL7Fc ARMORED CAR-T CELLS
WO2026006767A1 (en) 2024-06-28 2026-01-02 Dispatch Biotherapeutics, Inc. Tethered il-9/il-9r and related engineered cells and methods
WO2026072709A1 (en) 2024-09-25 2026-04-02 Orna Therapeutics, Inc. Chimeric antigen receptors targeting bcma

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