JP7669048B2 - 神経細胞を分化させる方法ならびに関連する組成物および使用方法 - Google Patents

神経細胞を分化させる方法ならびに関連する組成物および使用方法 Download PDF

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JP7669048B2
JP7669048B2 JP2022542668A JP2022542668A JP7669048B2 JP 7669048 B2 JP7669048 B2 JP 7669048B2 JP 2022542668 A JP2022542668 A JP 2022542668A JP 2022542668 A JP2022542668 A JP 2022542668A JP 7669048 B2 JP7669048 B2 JP 7669048B2
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ブラット－レアル，アンドレス
ローリング，ジャンヌ
トラン，ハ
ウィリアムズ，ロイ
モスマン，ジム
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アスペン ニューロサイエンス インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00—Drugs for disorders of the nervous system
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

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JP2022542668A 2020-01-13 2021-01-13 神経細胞を分化させる方法ならびに関連する組成物および使用方法 Active JP7669048B2 (ja)

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US (1) US20230059010A1 (https=)
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JP (2) JP7669048B2 (https=)
CN (2) CN119432744A (https=)
AU (2) AU2021209068B2 (https=)
BR (1) BR112022013843A2 (https=)
CA (1) CA3167713A1 (https=)
ES (1) ES3008210T3 (https=)
IL (1) IL294565B2 (https=)
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WO2023004366A1 (en) * 2021-07-21 2023-01-26 Aspen Neuroscience, Inc. Transposon-based modulation of gba1 and related compositions and uses thereof
WO2023004370A1 (en) * 2021-07-21 2023-01-26 Aspen Neuroscience, Inc. Aav-based modulation of gba1 and related compositions and uses thereof
WO2023137200A2 (en) * 2022-01-13 2023-07-20 The Board Of Trustees Of The Leland Stanford Junior University Generation of neural organizer organoids and midline assembloids from human pluripotent stem cells
JP2025512359A (ja) * 2022-04-11 2025-04-17 リサーチ ディベロップメント ファウンデーション 分化した神経細胞を作出および使用するための方法
WO2023201361A1 (en) 2022-04-15 2023-10-19 Aspen Neuroscience, Inc. Methods of classifying the differentiation state of cells and related compositions of differentiated cells
US12565639B2 (en) 2023-06-13 2026-03-03 Aspen Neuroscience, Inc. Methods for differentiating dopaminergic neurons from stem cells
US20250157580A1 (en) 2023-11-13 2025-05-15 Aspen Neuroscience, Inc. Methods of predicting dopamine production capability of differentiated neuronal cells

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WO2015034012A1 (ja) 2013-09-05 2015-03-12 国立大学法人京都大学 新規ドーパミン産生神経前駆細胞の誘導方法
WO2019103129A1 (ja) 2017-11-24 2019-05-31 住友化学株式会社 下垂体組織を含む細胞塊の製造方法及びその細胞塊

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WO2019103129A1 (ja) 2017-11-24 2019-05-31 住友化学株式会社 下垂体組織を含む細胞塊の製造方法及びその細胞塊

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MX2022008625A (es) 2022-09-09
EP4090734B1 (en) 2024-11-06
AU2021209068A1 (en) 2022-07-28
CA3167713A1 (en) 2021-07-22
JP2025118628A (ja) 2025-08-13
IL294565A (en) 2022-09-01
EP4090734C0 (en) 2024-11-06
CN115335511A (zh) 2022-11-11
EP4090734A1 (en) 2022-11-23
JP2023512453A (ja) 2023-03-27
IL294565B2 (en) 2025-04-01
BR112022013843A2 (pt) 2022-09-13
AU2024278587A1 (en) 2025-01-16
IL294565B1 (en) 2024-12-01
ES3008210T3 (en) 2025-03-21
SA522433282B1 (ar) 2025-04-21
AU2021209068B2 (en) 2024-09-19
WO2021146349A1 (en) 2021-07-22
US20230059010A1 (en) 2023-02-23
CN119432744A (zh) 2025-02-14

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