JP7632853B2 - ６，３’－ジヒドロキシエクオールの産生のための組成物 - Google Patents

６，３’－ジヒドロキシエクオールの産生のための組成物 Download PDF

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Publication number
JP7632853B2
JP7632853B2 JP2023503957A JP2023503957A JP7632853B2 JP 7632853 B2 JP7632853 B2 JP 7632853B2 JP 2023503957 A JP2023503957 A JP 2023503957A JP 2023503957 A JP2023503957 A JP 2023503957A JP 7632853 B2 JP7632853 B2 JP 7632853B2
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Japan
Prior art keywords
enzyme
equol
hydroxyequol
amino acid
acid sequence
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Japanese (ja)
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JPWO2022186355A1 (https=
JPWO2022186355A5 (https=
Inventor
彰収 松山
俊樹 古屋
大樹 野澤
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Daicel Corp
Tokyo University of Science
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Daicel Corp
Tokyo University of Science
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2023503957A 2021-03-03 2022-03-03 ６，３’－ジヒドロキシエクオールの産生のための組成物 Active JP7632853B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021033349 2021-03-03
JP2021033349 2021-03-03
PCT/JP2022/009235 WO2022186355A1 (ja) 2021-03-03 2022-03-03 ６，３'－ジヒドロキシエクオールの産生のための組成物

Publications (3)

Publication Number Publication Date
JPWO2022186355A1 JPWO2022186355A1 (https=) 2022-09-09
JPWO2022186355A5 JPWO2022186355A5 (https=) 2024-05-20
JP7632853B2 true JP7632853B2 (ja) 2025-02-19

Family

ID=83155396

Family Applications (1)

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JP2023503957A Active JP7632853B2 (ja) 2021-03-03 2022-03-03 ６，３’－ジヒドロキシエクオールの産生のための組成物

Country Status (2)

Country Link
JP (1) JP7632853B2 (https=)
WO (1) WO2022186355A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7449526B2 (ja) * 2018-12-07 2024-03-14 学校法人東京理科大学 エクオール誘導体の産生のための組成物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020092690A (ja) 2018-12-07 2020-06-18 学校法人東京理科大学 エクオール誘導体の産生のための組成物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020092690A (ja) 2018-12-07 2020-06-18 学校法人東京理科大学 エクオール誘導体の産生のための組成物

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HASHIMOTO, T, NOZAWA, D, MUKAI, K, MATSUYAMA, A, KURAMOCHI, K, and FURUYA, T，Monooxygenase-catalyzed regioselective hydroxylation for the synthesis of hydroxyequols，RCS Advances，2019年，Vol.9，p.21826-21830
RUEFER, C E, GLATT, H, and KULLING, S E，Structural elucidation of hydroxylated metabolites of the isoflavan equol by gas chromatography-mass，Drug Metabolism and Disposition，2006年，Vol. 34, No. 1，p.51-60
野澤大樹, 向井克之, 松山彰収, 古屋俊樹, 位置選択性の異なる二種類のエクオール水酸化酵素の機能解析,

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WO2022186355A1 (ja) 2022-09-09
JPWO2022186355A1 (https=) 2022-09-09

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