JP7616806B2 - 応答曲面および減次モデル化を使用した血流の推定のためのシステムおよび方法 - Google Patents

応答曲面および減次モデル化を使用した血流の推定のためのシステムおよび方法 Download PDF

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JP7616806B2
JP7616806B2 JP2021568016A JP2021568016A JP7616806B2 JP 7616806 B2 JP7616806 B2 JP 7616806B2 JP 2021568016 A JP2021568016 A JP 2021568016A JP 2021568016 A JP2021568016 A JP 2021568016A JP 7616806 B2 JP7616806 B2 JP 7616806B2
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blood flow
configurations
vasculature
patient
parameters
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セスラマン サンカラン，
デイビッド レセージ，
チャールズ テイラー，
ナン シャオ，
ヒュン ジン キム，
デイビッド スペイン，
ミハエル シャープ，
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ハートフロー， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10—Complex mathematical operations
    • G06F17/11—Complex mathematical operations for solving equations, e.g. nonlinear equations, general mathematical optimization problems
    • G06F17/13—Differential equations
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F30/00—Computer-aided design [CAD]
    • G06F30/20—Design optimisation, verification or simulation
    • G06F30/28—Design optimisation, verification or simulation using fluid dynamics, e.g. using Navier-Stokes equations or computational fluid dynamics [CFD]
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/101—Computer-aided simulation of surgical operations
    • A61B2034/105—Modelling of the patient, e.g. for ligaments or bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/107—Visualisation of planned trajectories or target regions
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F2113/00—Details relating to the application field
    • G06F2113/08—Fluids
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F2119/00—Details relating to the type or aim of the analysis or the optimisation
    • G06F2119/14—Force analysis or force optimisation, e.g. static or dynamic forces

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  • Health & Medical Sciences (AREA)
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  • Primary Health Care (AREA)
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  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Data Mining & Analysis (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Databases & Information Systems (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Mathematical Analysis (AREA)
  • Mathematical Optimization (AREA)
  • Pure & Applied Mathematics (AREA)
  • Robotics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Computational Mathematics (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Algebra (AREA)
  • General Engineering & Computer Science (AREA)
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  • Operations Research (AREA)
  • Computing Systems (AREA)
  • Fluid Mechanics (AREA)
  • Computer Hardware Design (AREA)
  • Evolutionary Computation (AREA)
JP2021568016A 2019-05-17 2020-05-15 応答曲面および減次モデル化を使用した血流の推定のためのシステムおよび方法 Active JP7616806B2 (ja)

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US201962849489P 2019-05-17 2019-05-17
US62/849,489 2019-05-17
PCT/US2020/033239 WO2020236639A1 (en) 2019-05-17 2020-05-15 System and methods for estimation of blood flow using response surface and reduced order modeling

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JP2022533345A JP2022533345A (ja) 2022-07-22
JP2022533345A5 JP2022533345A5 (https=) 2024-09-25
JP7616806B2 true JP7616806B2 (ja) 2025-01-17

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Cited By (6)

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US12396695B2 (en) 2020-01-07 2025-08-26 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12440180B2 (en) 2022-03-10 2025-10-14 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination
US12499539B2 (en) 2020-01-07 2025-12-16 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12558048B2 (en) 2020-01-07 2026-02-24 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12589032B2 (en) 2020-10-16 2026-03-31 Pulsemedica Corp. Opthalmological imaging and laser delivery device, system and methods
US12599352B2 (en) 2022-03-10 2026-04-14 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination

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JP2018515167A (ja) * 2015-04-02 2018-06-14 ハートフロー， インコーポレイテッド 血管網と潅流組織の機能的関連性を特定し可視化するシステム及び方法
US12406365B2 (en) 2022-03-10 2025-09-02 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination
US20250217981A1 (en) 2022-03-10 2025-07-03 Cleerly, Inc. Systems, methods, and devices for image-based plaque analysis and risk determination
CN115221804B (zh) * 2022-06-08 2025-07-11 中国科学院深圳先进技术研究院 人工肺血流的流场计算方法、装置、设备及存储介质

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US8200466B2 (en) * 2008-07-21 2012-06-12 The Board Of Trustees Of The Leland Stanford Junior University Method for tuning patient-specific cardiovascular simulations
US8315812B2 (en) 2010-08-12 2012-11-20 Heartflow, Inc. Method and system for patient-specific modeling of blood flow
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US10307131B2 (en) * 2015-07-17 2019-06-04 Heartflow, Inc. Systems and methods for assessing the severity of plaque and/or stenotic lesions using contrast distribution predictions and measurements
CN105326486B (zh) * 2015-12-08 2017-08-25 博动医学影像科技（上海）有限公司 血管压力差与血流储备分数的计算方法及系统
JP6829262B2 (ja) * 2016-02-26 2021-02-10 ハートフロー， インコーポレイテッド 画像ベースの患者固有の血流力学的モデルにおいて解像されていない血管を特定してモデル化するためのシステム及び方法
JP7100627B2 (ja) * 2016-09-20 2022-07-13 ハートフロー， インコーポレイテッド 次数低減モデル及び／または機械学習を使用して血流特性を推定するためのシステム及び方法

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WO2020160771A1 (en) 2019-02-06 2020-08-13 Universität Zürich System and method for determining fluid flow through a subject conduit

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12396695B2 (en) 2020-01-07 2025-08-26 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12499539B2 (en) 2020-01-07 2025-12-16 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12555228B2 (en) 2020-01-07 2026-02-17 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12558048B2 (en) 2020-01-07 2026-02-24 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12589032B2 (en) 2020-10-16 2026-03-31 Pulsemedica Corp. Opthalmological imaging and laser delivery device, system and methods
US12440180B2 (en) 2022-03-10 2025-10-14 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination
US12599352B2 (en) 2022-03-10 2026-04-14 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination

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Publication number Publication date
CN113811956B (zh) 2025-08-19
CA3132472A1 (en) 2020-11-26
US20200360088A1 (en) 2020-11-19
AU2020278589A1 (en) 2022-01-06
WO2020236639A1 (en) 2020-11-26
KR102915024B1 (ko) 2026-01-21
US11707325B2 (en) 2023-07-25
US12096990B2 (en) 2024-09-24
KR20260022453A (ko) 2026-02-19
EP3970162A1 (en) 2022-03-23
CN113811956A (zh) 2021-12-17
KR20220009995A (ko) 2022-01-25
JP2022533345A (ja) 2022-07-22
US20230310085A1 (en) 2023-10-05
US20240407849A1 (en) 2024-12-12

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