JP7585207B2 - 子宮瘢痕形成を予防するための間葉系幹細胞シートの使用 - Google Patents
子宮瘢痕形成を予防するための間葉系幹細胞シートの使用 Download PDFInfo
- Publication number
- JP7585207B2 JP7585207B2 JP2021541025A JP2021541025A JP7585207B2 JP 7585207 B2 JP7585207 B2 JP 7585207B2 JP 2021541025 A JP2021541025 A JP 2021541025A JP 2021541025 A JP2021541025 A JP 2021541025A JP 7585207 B2 JP7585207 B2 JP 7585207B2
- Authority
- JP
- Japan
- Prior art keywords
- cell
- msc
- sheet
- mscs
- huc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/22—Materials or treatment for tissue regeneration for reconstruction of hollow organs, e.g. bladder, esophagus, urether, uterus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Materials For Medical Uses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024194131A JP2025024004A (ja) | 2019-01-16 | 2024-11-06 | 子宮瘢痕形成を予防するための間葉系幹細胞シートの使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962793195P | 2019-01-16 | 2019-01-16 | |
| US62/793,195 | 2019-01-16 | ||
| PCT/US2020/013622 WO2020150310A1 (en) | 2019-01-16 | 2020-01-15 | Use of mesenchymal stem cell sheets for preventing uterine scar formation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024194131A Division JP2025024004A (ja) | 2019-01-16 | 2024-11-06 | 子宮瘢痕形成を予防するための間葉系幹細胞シートの使用 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022523460A JP2022523460A (ja) | 2022-04-25 |
| JP2022523460A5 JP2022523460A5 (https=) | 2022-12-26 |
| JPWO2020150310A5 JPWO2020150310A5 (https=) | 2022-12-26 |
| JP7585207B2 true JP7585207B2 (ja) | 2024-11-18 |
Family
ID=71614029
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021541025A Active JP7585207B2 (ja) | 2019-01-16 | 2020-01-15 | 子宮瘢痕形成を予防するための間葉系幹細胞シートの使用 |
| JP2024194131A Pending JP2025024004A (ja) | 2019-01-16 | 2024-11-06 | 子宮瘢痕形成を予防するための間葉系幹細胞シートの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024194131A Pending JP2025024004A (ja) | 2019-01-16 | 2024-11-06 | 子宮瘢痕形成を予防するための間葉系幹細胞シートの使用 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20210386790A1 (https=) |
| EP (1) | EP3911734A4 (https=) |
| JP (2) | JP7585207B2 (https=) |
| WO (1) | WO2020150310A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240067279A (ko) * | 2021-10-01 | 2024-05-16 | 유니버시티 오브 유타 리써치 파운데이션 | 인간 골수-유래 중간엽 줄기세포 시트 및 이의 생산 방법 |
| CN114632146A (zh) * | 2022-03-01 | 2022-06-17 | 康膝生物医疗(深圳)有限公司 | 一种用于子宫内膜修复的温敏型复合水凝胶制剂的制备方法及其应用 |
| CN114984052A (zh) * | 2022-07-25 | 2022-09-02 | 京东方科技集团股份有限公司 | 人源间充质干细胞膜片在子宫瘢痕治疗中的用途 |
| CN116712597B (zh) * | 2023-06-12 | 2026-04-17 | 广州正源生物技术有限公司 | 一种复合生物敷料及其制备方法和应用 |
| KR20250034265A (ko) * | 2023-09-01 | 2025-03-11 | 주식회사 셀인셀즈 | 중간엽 줄기세포 스페로이드를 포함하는 피부 상처 또는 흉터 치료용 조성물 |
| CN118948746A (zh) * | 2024-07-26 | 2024-11-15 | 安徽黑豆生物科技有限公司 | 一种负载间充质干细胞的重构细胞外基质凝胶及其在制备治疗宫腔粘连产品中的应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015503918A (ja) | 2011-12-30 | 2015-02-05 | パテル、アミット | 同種異系細胞の医療用途の誘導のための方法及び組成物並びに治療的利用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2006093153A1 (ja) * | 2005-02-28 | 2008-08-07 | 株式会社セルシード | 培養細胞シート、製造方法及びその利用した組織修復方法 |
| CN103097518B (zh) * | 2010-09-14 | 2015-10-14 | 学校法人东京女子医科大学 | 细胞片叠层化物的制造方法、由该方法得到的具有血管网的细胞片叠层化物及其利用方法 |
| US20140099709A1 (en) * | 2012-06-19 | 2014-04-10 | Organovo, Inc. | Engineered three-dimensional connective tissue constructs and methods of making the same |
| US9498498B2 (en) * | 2013-03-15 | 2016-11-22 | Avita International Ltd. | Adipose tissue mesenchymal stem cells and methods of use to treat or inhibit uterine disorders |
| JP6494393B2 (ja) * | 2015-04-21 | 2019-04-03 | 学校法人東京女子医科大学 | 子宮組織治療用細胞組成物及びその製造方法 |
| US20180362923A1 (en) * | 2015-12-11 | 2018-12-20 | Lei Guo | Method for separating and extracting huc-msc from wharton's jelly tissue of umbilical cord |
| CN106730013A (zh) * | 2016-12-06 | 2017-05-31 | 徐妍 | 用于预防宫腔粘连及子宫内膜损伤修复的细胞制剂及其制备方法 |
| JP7130198B2 (ja) * | 2017-06-29 | 2022-09-05 | 日本光電工業株式会社 | 積層化細胞シートの製造方法、及びそれにより作製される積層化細胞シート |
-
2020
- 2020-01-15 US US17/422,646 patent/US20210386790A1/en active Pending
- 2020-01-15 JP JP2021541025A patent/JP7585207B2/ja active Active
- 2020-01-15 WO PCT/US2020/013622 patent/WO2020150310A1/en not_active Ceased
- 2020-01-15 EP EP20741027.5A patent/EP3911734A4/en active Pending
-
2024
- 2024-11-06 JP JP2024194131A patent/JP2025024004A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015503918A (ja) | 2011-12-30 | 2015-02-05 | パテル、アミット | 同種異系細胞の医療用途の誘導のための方法及び組成物並びに治療的利用 |
Non-Patent Citations (1)
| Title |
|---|
| Am. J. Obstet. Gynecol.,2018年12月24日,220, [1,Supplement],p.S621-622,<DOI:10.1016/j.ajog.2018.11.989> |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3911734A1 (en) | 2021-11-24 |
| US20210386790A1 (en) | 2021-12-16 |
| JP2025024004A (ja) | 2025-02-19 |
| JP2022523460A (ja) | 2022-04-25 |
| WO2020150310A1 (en) | 2020-07-23 |
| WO2020150310A9 (en) | 2021-09-02 |
| EP3911734A4 (en) | 2022-11-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7585207B2 (ja) | 子宮瘢痕形成を予防するための間葉系幹細胞シートの使用 | |
| Yeh et al. | Cardiac repair with injectable cell sheet fragments of human amniotic fluid stem cells in an immune-suppressed rat model | |
| US9902933B2 (en) | Method of producing retinal pigment epithelial cell sheet | |
| Lee et al. | The use of injectable spherically symmetric cell aggregates self-assembled in a thermo-responsive hydrogel for enhanced cell transplantation | |
| Chen et al. | Transplantation of menstrual blood-derived mesenchymal stem cells (MbMSCs) promotes the regeneration of mechanical injuried endometrium | |
| JP2009527250A (ja) | 結膜組織系 | |
| Utheim et al. | Concise review: altered versus unaltered amniotic membrane as a substrate for limbal epithelial cells | |
| JP2025000600A (ja) | ヒト臍帯間葉系幹細胞シート及びその製造方法 | |
| JP5426073B2 (ja) | ヒト胚盤胞由来幹細胞(hBS細胞)のフィーダー支持からフィーダーなしの培養系への効率的な移送方法 | |
| CN101801352B (zh) | 用于治疗小便失禁的含有来自蜕膜或脂肪的干细胞的细胞治疗剂 | |
| Aghamollaei et al. | Safety of grafting acellular human corneal lenticule seeded with Wharton's Jelly-Derived Mesenchymal Stem Cells in an experimental animal model | |
| JP5661048B2 (ja) | 脂肪細胞シート、その三次元構造体、及びそれらの製造方法 | |
| ES2679271T3 (es) | Células derivadas del tejido cardiaco | |
| Sehic et al. | Transplantation of a bioengineered tissue patch promotes uterine repair in the sheep | |
| US20200390937A1 (en) | Sheet-shaped cell culture for regeneration of digestive tract | |
| US20100203575A1 (en) | In Vitro Beating Heart Model | |
| WO2012085298A1 (es) | Gel de fibrina que contiene células del limbo esclerocorneal y su uso en bioingeniería de la superficie ocular | |
| Nagireddy et al. | Autologous PRP for the management of thin endometrium in frozen embryo transfer cycles: would it improve the outcome? | |
| Hohn et al. | A three-dimensional organ culture model for the study of implantation of rabbit blastocyst in vitro | |
| CN119455127A (zh) | 一种用于薄型子宫内膜修复生物支架的制备方法 | |
| Asgharzadeh et al. | The progress in tissue engineering of uterus | |
| Koike et al. | Manuscript title | |
| WO2023050325A1 (zh) | Cd90+人羊膜上皮细胞在治疗移植物抗宿主病中的用途 | |
| WO2022204904A1 (zh) | 人羊膜上皮细胞在制备用于治疗和/或改善宫腔粘连疾病的药物中的用途 | |
| WO2011151043A1 (en) | Process for differentiating stem cells of the amniotic membrane |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20221216 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20221216 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20231121 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20240220 |
|
| RD01 | Notification of change of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7426 Effective date: 20240305 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20240305 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20240514 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20241008 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20241106 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 7585207 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |