JP7585207B2 - 子宮瘢痕形成を予防するための間葉系幹細胞シートの使用 - Google Patents

子宮瘢痕形成を予防するための間葉系幹細胞シートの使用 Download PDF

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JP7585207B2
JP7585207B2 JP2021541025A JP2021541025A JP7585207B2 JP 7585207 B2 JP7585207 B2 JP 7585207B2 JP 2021541025 A JP2021541025 A JP 2021541025A JP 2021541025 A JP2021541025 A JP 2021541025A JP 7585207 B2 JP7585207 B2 JP 7585207B2
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cell
msc
sheet
mscs
huc
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JP2022523460A (ja
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吾郎 藏本
光夫 岡野
シルバー,ロバート
グレイガー,デイビッド
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UNIVERSITY OF UTHA RESEARCHFOUNDATION
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/51Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/22Materials or treatment for tissue regeneration for reconstruction of hollow organs, e.g. bladder, esophagus, urether, uterus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
JP2021541025A 2019-01-16 2020-01-15 子宮瘢痕形成を予防するための間葉系幹細胞シートの使用 Active JP7585207B2 (ja)

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JP2024194131A JP2025024004A (ja) 2019-01-16 2024-11-06 子宮瘢痕形成を予防するための間葉系幹細胞シートの使用

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US201962793195P 2019-01-16 2019-01-16
US62/793,195 2019-01-16
PCT/US2020/013622 WO2020150310A1 (en) 2019-01-16 2020-01-15 Use of mesenchymal stem cell sheets for preventing uterine scar formation

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JP2024194131A Division JP2025024004A (ja) 2019-01-16 2024-11-06 子宮瘢痕形成を予防するための間葉系幹細胞シートの使用

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JP2022523460A JP2022523460A (ja) 2022-04-25
JP2022523460A5 JP2022523460A5 (https=) 2022-12-26
JPWO2020150310A5 JPWO2020150310A5 (https=) 2022-12-26
JP7585207B2 true JP7585207B2 (ja) 2024-11-18

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JP2024194131A Pending JP2025024004A (ja) 2019-01-16 2024-11-06 子宮瘢痕形成を予防するための間葉系幹細胞シートの使用

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US (1) US20210386790A1 (https=)
EP (1) EP3911734A4 (https=)
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WO (1) WO2020150310A1 (https=)

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KR20240067279A (ko) * 2021-10-01 2024-05-16 유니버시티 오브 유타 리써치 파운데이션 인간 골수-유래 중간엽 줄기세포 시트 및 이의 생산 방법
CN114632146A (zh) * 2022-03-01 2022-06-17 康膝生物医疗(深圳)有限公司 一种用于子宫内膜修复的温敏型复合水凝胶制剂的制备方法及其应用
CN114984052A (zh) * 2022-07-25 2022-09-02 京东方科技集团股份有限公司 人源间充质干细胞膜片在子宫瘢痕治疗中的用途
CN116712597B (zh) * 2023-06-12 2026-04-17 广州正源生物技术有限公司 一种复合生物敷料及其制备方法和应用
KR20250034265A (ko) * 2023-09-01 2025-03-11 주식회사 셀인셀즈 중간엽 줄기세포 스페로이드를 포함하는 피부 상처 또는 흉터 치료용 조성물
CN118948746A (zh) * 2024-07-26 2024-11-15 安徽黑豆生物科技有限公司 一种负载间充质干细胞的重构细胞外基质凝胶及其在制备治疗宫腔粘连产品中的应用

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JP2015503918A (ja) 2011-12-30 2015-02-05 パテル、アミット 同種異系細胞の医療用途の誘導のための方法及び組成物並びに治療的利用

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JPWO2006093153A1 (ja) * 2005-02-28 2008-08-07 株式会社セルシード 培養細胞シート、製造方法及びその利用した組織修復方法
CN103097518B (zh) * 2010-09-14 2015-10-14 学校法人东京女子医科大学 细胞片叠层化物的制造方法、由该方法得到的具有血管网的细胞片叠层化物及其利用方法
US20140099709A1 (en) * 2012-06-19 2014-04-10 Organovo, Inc. Engineered three-dimensional connective tissue constructs and methods of making the same
US9498498B2 (en) * 2013-03-15 2016-11-22 Avita International Ltd. Adipose tissue mesenchymal stem cells and methods of use to treat or inhibit uterine disorders
JP6494393B2 (ja) * 2015-04-21 2019-04-03 学校法人東京女子医科大学 子宮組織治療用細胞組成物及びその製造方法
US20180362923A1 (en) * 2015-12-11 2018-12-20 Lei Guo Method for separating and extracting huc-msc from wharton's jelly tissue of umbilical cord
CN106730013A (zh) * 2016-12-06 2017-05-31 徐妍 用于预防宫腔粘连及子宫内膜损伤修复的细胞制剂及其制备方法
JP7130198B2 (ja) * 2017-06-29 2022-09-05 日本光電工業株式会社 積層化細胞シートの製造方法、及びそれにより作製される積層化細胞シート

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015503918A (ja) 2011-12-30 2015-02-05 パテル、アミット 同種異系細胞の医療用途の誘導のための方法及び組成物並びに治療的利用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Am. J. Obstet. Gynecol.,2018年12月24日,220, [1,Supplement],p.S621-622,<DOI:10.1016/j.ajog.2018.11.989>

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EP3911734A1 (en) 2021-11-24
US20210386790A1 (en) 2021-12-16
JP2025024004A (ja) 2025-02-19
JP2022523460A (ja) 2022-04-25
WO2020150310A1 (en) 2020-07-23
WO2020150310A9 (en) 2021-09-02
EP3911734A4 (en) 2022-11-09

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