JP7516049B2 - 生体内血液濾過のための血液濾過器 - Google Patents

生体内血液濾過のための血液濾過器 Download PDF

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Publication number
JP7516049B2
JP7516049B2 JP2019571261A JP2019571261A JP7516049B2 JP 7516049 B2 JP7516049 B2 JP 7516049B2 JP 2019571261 A JP2019571261 A JP 2019571261A JP 2019571261 A JP2019571261 A JP 2019571261A JP 7516049 B2 JP7516049 B2 JP 7516049B2
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Japan
Prior art keywords
blood
region
section
channel
hemofilter
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JP2019571261A
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English (en)
Japanese (ja)
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JP2020524581A (ja
JP2020524581A5 (https=
Inventor
ロイ,シューボ
フィッセル,ウイリアム
ライト,ネイサン
グディン,マーク
ゴエベル,スティーブン
バック,アマンダ
グロゼク,ジョーイ
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Vanderbilt University
University of California San Diego UCSD
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Vanderbilt University
University of California San Diego UCSD
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Publication of JP2020524581A5 publication Critical patent/JP2020524581A5/ja
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621Constructional aspects thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621Constructional aspects thereof
    • A61M1/1631Constructional aspects thereof having non-tubular membranes, e.g. sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165Filtering accessories, e.g. blood filters, filters for infusion liquids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D63/00Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08Flat membrane modules
    • B01D63/082Flat membrane modules comprising a stack of flat membranes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D63/00Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08Flat membrane modules
    • B01D63/082Flat membrane modules comprising a stack of flat membranes
    • B01D63/084Flat membrane modules comprising a stack of flat membranes at least one flow duct intersecting the membranes
    • B01D63/085Flat membrane modules comprising a stack of flat membranes at least one flow duct intersecting the membranes specially adapted for two fluids in mass exchange flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1678Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes intracorporal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/04General characteristics of the apparatus implanted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3334Measuring or controlling the flow rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/75General characteristics of the apparatus with filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/11Laminar flow
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2313/00Details relating to membrane modules or apparatus
    • B01D2313/10Specific supply elements
    • B01D2313/105Supply manifolds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2313/00Details relating to membrane modules or apparatus
    • B01D2313/12Specific discharge elements
    • B01D2313/125Discharge manifolds
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28HEAT EXCHANGE IN GENERAL
    • F28FDETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F9/00Casings; Header boxes; Auxiliary supports for elements; Auxiliary members within casings
    • F28F9/02Header boxes; End plates
    • F28F2009/0285Other particular headers or end plates
    • F28F2009/029Other particular headers or end plates with increasing or decreasing cross-section, e.g. having conical shape

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • External Artificial Organs (AREA)
JP2019571261A 2017-06-21 2018-06-20 生体内血液濾過のための血液濾過器 Active JP7516049B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762523131P 2017-06-21 2017-06-21
US62/523,131 2017-06-21
PCT/US2018/038548 WO2018237036A1 (en) 2017-06-21 2018-06-20 HEMOFILTER FOR IN VIVO BLOOD FILTRATION

Publications (3)

Publication Number Publication Date
JP2020524581A JP2020524581A (ja) 2020-08-20
JP2020524581A5 JP2020524581A5 (https=) 2024-05-07
JP7516049B2 true JP7516049B2 (ja) 2024-07-16

Family

ID=64736140

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019571261A Active JP7516049B2 (ja) 2017-06-21 2018-06-20 生体内血液濾過のための血液濾過器

Country Status (7)

Country Link
US (3) US11511027B2 (https=)
EP (2) EP4600600A3 (https=)
JP (1) JP7516049B2 (https=)
AU (1) AU2018289514B2 (https=)
CA (1) CA3068008A1 (https=)
SG (1) SG11201912800RA (https=)
WO (1) WO2018237036A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10874786B2 (en) * 2017-05-31 2020-12-29 Nephrodite LLC Implantable dialysis device
WO2018237036A1 (en) * 2017-06-21 2018-12-27 The Regents Of The University Of California HEMOFILTER FOR IN VIVO BLOOD FILTRATION
EP4523717A3 (en) * 2018-05-18 2025-04-23 The Regents of The University of California In vivo blood filtration membranes and devices
EP4085940A1 (en) 2021-05-07 2022-11-09 Imec VZW A method and a maintenance device for automatic maintenance of an autonomous dialysis system

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009131573A (ja) 2007-11-28 2009-06-18 Daiki Iwami 体内完全埋め込み型の人工腎臓の構成および使用法
JP2010069278A (ja) 2008-09-22 2010-04-02 成一 ▲高▼杉 体内に埋め込み可能な体液浄化装置

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038191A (en) 1975-10-14 1977-07-26 Davis Harold R Manifold for ultra filtration machine
JPS56104673A (en) * 1980-01-23 1981-08-20 Otsubo Osamu Internally buried artificial kidney
GB2086762B (en) * 1980-11-12 1984-01-18 Sartorius Gmbh Device for mass transfer between fluids
JP4084869B2 (ja) 1997-11-10 2008-04-30 保博 山本 体内留置型浄化装置
US6561996B1 (en) 1998-05-19 2003-05-13 Transvivo, Inc. Apparatus and method for in vivo hemodialysis
KR20010072251A (ko) 1998-08-28 2001-07-31 추후제출 자동 호스의 투석 필터
DE10049256A1 (de) 2000-10-05 2002-04-11 Behr Gmbh & Co Serpentinen-Wärmeübertrager
US8038639B2 (en) * 2004-11-04 2011-10-18 Baxter International Inc. Medical fluid system with flexible sheeting disposable unit
US20070246106A1 (en) 2006-04-25 2007-10-25 Velocys Inc. Flow Distribution Channels To Control Flow in Process Channels
US9403126B2 (en) 2007-01-10 2016-08-02 The Regents Of The University Of Michigan Ultrafiltration membrane, device, bioartificial organ, and related methods
US9017277B2 (en) 2011-05-02 2015-04-28 Medtronic, Inc. System and implantable device for treating chronic kidney disease
WO2018237036A1 (en) * 2017-06-21 2018-12-27 The Regents Of The University Of California HEMOFILTER FOR IN VIVO BLOOD FILTRATION

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009131573A (ja) 2007-11-28 2009-06-18 Daiki Iwami 体内完全埋め込み型の人工腎臓の構成および使用法
JP2010069278A (ja) 2008-09-22 2010-04-02 成一 ▲高▼杉 体内に埋め込み可能な体液浄化装置

Also Published As

Publication number Publication date
US20240399041A1 (en) 2024-12-05
US20200114058A1 (en) 2020-04-16
EP3641846B1 (en) 2025-10-15
US11957824B2 (en) 2024-04-16
EP3641846A1 (en) 2020-04-29
AU2018289514B2 (en) 2023-11-23
EP4600600A3 (en) 2025-11-12
JP2020524581A (ja) 2020-08-20
US12318522B2 (en) 2025-06-03
EP4600600A2 (en) 2025-08-13
US11511027B2 (en) 2022-11-29
AU2018289514A1 (en) 2020-01-16
SG11201912800RA (en) 2020-01-30
CA3068008A1 (en) 2018-12-27
EP3641846A4 (en) 2021-03-17
WO2018237036A1 (en) 2018-12-27
US20230173156A1 (en) 2023-06-08

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