JP7514224B2 - マイクロサテライト不安定性を評価するための方法およびシステム - Google Patents

マイクロサテライト不安定性を評価するための方法およびシステム Download PDF

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JP7514224B2
JP7514224B2 JP2021514069A JP2021514069A JP7514224B2 JP 7514224 B2 JP7514224 B2 JP 7514224B2 JP 2021514069 A JP2021514069 A JP 2021514069A JP 2021514069 A JP2021514069 A JP 2021514069A JP 7514224 B2 JP7514224 B2 JP 7514224B2
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アレクサンダー デ ヨング ロバートソン,
ニコル ジャシンダ ランバート,
ハルク テツカン,
ラム ヤラマンチリ,
ニール ピーターマン,
ロヒト カンナパン スリヴァス,
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レクセント バイオ, インコーポレイテッド
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    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • C12Q2600/00Oligonucleotides characterized by their use
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    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
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    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection

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JP2021514069A 2018-09-14 2019-09-13 マイクロサテライト不安定性を評価するための方法およびシステム Active JP7514224B2 (ja)

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US201862731718P 2018-09-14 2018-09-14
US62/731,718 2018-09-14
PCT/US2019/051138 WO2020056347A1 (en) 2018-09-14 2019-09-13 Methods and systems for assessing microsatellite instability

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JP2022500764A JP2022500764A (ja) 2022-01-04
JP2022500764A5 JP2022500764A5 (https=) 2022-09-22
JPWO2020056347A5 JPWO2020056347A5 (https=) 2022-09-22
JP7514224B2 true JP7514224B2 (ja) 2024-07-10

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US (1) US20210358569A1 (https=)
EP (1) EP3850111A4 (https=)
JP (1) JP7514224B2 (https=)
KR (1) KR20210092196A (https=)
CN (1) CN112955570B (https=)
AU (1) AU2019339511A1 (https=)
BR (1) BR112021004763A2 (https=)
CA (1) CA3112562A1 (https=)
IL (1) IL281417A (https=)
SG (1) SG11202102528UA (https=)
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JP7539367B2 (ja) 2018-08-31 2024-08-23 ガーダント ヘルス, インコーポレイテッド 無細胞dnaにおけるマイクロサテライト不安定性の検出
KR102781271B1 (ko) * 2021-08-10 2025-03-17 (주)디엑솜 현미부수체 지역의 서열 길이의 최대값과 최소값의 차이를 이용한 현미부수체 불안정성 진단방법
KR102688594B1 (ko) * 2021-08-10 2024-07-24 (주)디엑솜 현미부수체 지역의 서열 길이의 변화율을 이용한 현미부수체 불안정성 진단방법
CN114464257B (zh) * 2022-03-15 2025-02-25 郑州安图生物工程股份有限公司 一种基于二代测序的微卫星不稳定性检测方法及装置
CN118942537B (zh) * 2023-09-21 2026-01-23 杭州链康医学检验实验室有限公司 一种构建标记微卫星位点稳定性预测模型的方法

Citations (4)

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Publication number Priority date Publication date Assignee Title
US20140235456A1 (en) 2012-12-17 2014-08-21 Virginia Tech Intellectual Properties, Inc. Methods and Compositions for Identifying Global Microsatellite Instability and for Characterizing Informative Microsatellite Loci
JP2015516144A (ja) 2012-04-10 2015-06-08 ブイアイビー ブイゼットダブリュVib Vzw 癌におけるマイクロサテライト不安定性を検出しdna塩基除去修復経路の阻害による合成致死性を決定するための新規なマーカー
WO2018037231A1 (en) 2016-08-24 2018-03-01 The University Of Newcastle Upon Tyne Methods of identifying microsatellite instability
WO2018137678A1 (zh) 2017-01-25 2018-08-02 广州燃石医学检验所有限公司 一种基于二代测序的同时检测微卫星位点稳定性和基因组变化的方法

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WO2017008165A1 (en) * 2015-07-14 2017-01-19 British Columbia Cancer Agency Branch Classification method and treatment for endometrial cancers
EP3405574A4 (en) * 2016-01-22 2019-10-02 Grail, Inc. VARIANTS-BASED SICKNESS DIAGNOSTICS AND PURSUIT
CA3083787A1 (en) * 2017-12-01 2019-06-06 Personal Genome Diagnositics Inc. Process for microsatellite instability detection

Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
JP2015516144A (ja) 2012-04-10 2015-06-08 ブイアイビー ブイゼットダブリュVib Vzw 癌におけるマイクロサテライト不安定性を検出しdna塩基除去修復経路の阻害による合成致死性を決定するための新規なマーカー
US20140235456A1 (en) 2012-12-17 2014-08-21 Virginia Tech Intellectual Properties, Inc. Methods and Compositions for Identifying Global Microsatellite Instability and for Characterizing Informative Microsatellite Loci
WO2018037231A1 (en) 2016-08-24 2018-03-01 The University Of Newcastle Upon Tyne Methods of identifying microsatellite instability
WO2018137678A1 (zh) 2017-01-25 2018-08-02 广州燃石医学检验所有限公司 一种基于二代测序的同时检测微卫星位点稳定性和基因组变化的方法

Non-Patent Citations (3)

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Title
BARZI Afsaneh,外7名,"Assessment of microsatellite instability (MSI) in cell free DNA (cfDNA) of colorectal cancers (CRC) patients (pts)",Journal of Clinical Oncology [online],米国,American Society of Clinical Oncology,2018年02月26日,[2023年11月14日検索],インターネット<URL:https://ascopubs.org/doi/abs/10.1200/JCO.2018.36.4_suppl.672>
G Sozzi,外7名,"診断時および肺癌患者の追跡中の血漿中の循環腫瘍DNAの分析 - Bibgraph (ビブグラフ)|PubMedを日本語で論文検索",Cancer research [online],日本,Bibgraph,2001年06月15日,[2023年11月13日検索],インターネット<URL:https://bibgraph.hpcr.jp/abst/pubmed/11406535?click_by=p_ref>
HEGELE A. Robert,外4名,"Genome-wide scanning for type 2 diabetes susceptibility in Canadian Oji-Cree, using 190 microsatellite markers",Jpn Soc Hum Genet and Springer-Verlag 1999 [online],Jpn Soc Hum Genet and Springer-Verlag 1999,1998年07月17日,[2023年11月13日検索],インターネット<URL:https://www.nature.com/articles/jhg19992>

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BR112021004763A2 (pt) 2021-08-03
KR20210092196A (ko) 2021-07-23
CA3112562A1 (en) 2020-03-19
SG11202102528UA (en) 2021-04-29
CN112955570B (zh) 2025-01-21
WO2020056347A1 (en) 2020-03-19
EP3850111A4 (en) 2022-06-29
JP2022500764A (ja) 2022-01-04
CN112955570A (zh) 2021-06-11
IL281417A (en) 2021-04-29
US20210358569A1 (en) 2021-11-18
AU2019339511A1 (en) 2021-05-13
EP3850111A1 (en) 2021-07-21

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