KR20210092196A - 미소부수체 불안정성을 평가하기 위한 방법 및 시스템 - Google Patents

미소부수체 불안정성을 평가하기 위한 방법 및 시스템 Download PDF

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KR20210092196A
KR20210092196A KR1020217010575A KR20217010575A KR20210092196A KR 20210092196 A KR20210092196 A KR 20210092196A KR 1020217010575 A KR1020217010575 A KR 1020217010575A KR 20217010575 A KR20217010575 A KR 20217010575A KR 20210092196 A KR20210092196 A KR 20210092196A
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microsatellite
subject
readable medium
detected
transitory computer
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알렉산더 데 종 로버트슨
니콜 재신다 램버트
할룩 테츠칸
램 야라만칠리
닐 피터맨
로히스 칸나판 스리바스
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렉센트 바이오, 인크.
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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/40—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection

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KR1020217010575A 2018-09-14 2019-09-13 미소부수체 불안정성을 평가하기 위한 방법 및 시스템 Withdrawn KR20210092196A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862731718P 2018-09-14 2018-09-14
US62/731,718 2018-09-14
PCT/US2019/051138 WO2020056347A1 (en) 2018-09-14 2019-09-13 Methods and systems for assessing microsatellite instability

Publications (1)

Publication Number Publication Date
KR20210092196A true KR20210092196A (ko) 2021-07-23

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KR1020217010575A Withdrawn KR20210092196A (ko) 2018-09-14 2019-09-13 미소부수체 불안정성을 평가하기 위한 방법 및 시스템

Country Status (11)

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US (1) US20210358569A1 (https=)
EP (1) EP3850111A4 (https=)
JP (1) JP7514224B2 (https=)
KR (1) KR20210092196A (https=)
CN (1) CN112955570B (https=)
AU (1) AU2019339511A1 (https=)
BR (1) BR112021004763A2 (https=)
CA (1) CA3112562A1 (https=)
IL (1) IL281417A (https=)
SG (1) SG11202102528UA (https=)
WO (1) WO2020056347A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023018026A1 (ko) * 2021-08-10 2023-02-16 (주)디엑솜 현미부수체 지역의 서열 길이의 최대값과 최소값의 차이를 이용한 현미부수체 불안정성 진단방법
WO2023018024A1 (ko) * 2021-08-10 2023-02-16 (주)디엑솜 현미부수체 지역의 서열 길이의 변화율을 이용한 현미부수체 불안정성 진단방법

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121354685A (zh) 2018-08-31 2026-01-16 夸登特健康公司 无细胞dna中的微卫星不稳定性检测
CN114464257B (zh) * 2022-03-15 2025-02-25 郑州安图生物工程股份有限公司 一种基于二代测序的微卫星不稳定性检测方法及装置
CN118800326B (zh) * 2023-09-21 2025-10-17 杭州链康医学检验实验室有限公司 一种构建msi总体状态预测模型的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2869729C (en) * 2012-04-10 2021-12-28 Vib Vzw Novel markers for detecting microsatellite instability in cancer and determining synthetic lethality with inhibition of the dna base excision repair pathway
US20140235456A1 (en) * 2012-12-17 2014-08-21 Virginia Tech Intellectual Properties, Inc. Methods and Compositions for Identifying Global Microsatellite Instability and for Characterizing Informative Microsatellite Loci
WO2017008165A1 (en) * 2015-07-14 2017-01-19 British Columbia Cancer Agency Branch Classification method and treatment for endometrial cancers
EP3405574A4 (en) * 2016-01-22 2019-10-02 Grail, Inc. VARIANTS-BASED SICKNESS DIAGNOSTICS AND PURSUIT
GB201614474D0 (en) * 2016-08-24 2016-10-05 Univ Of Newcastle Upon Tyne The Methods of identifying microsatellite instability
CN106755501B (zh) * 2017-01-25 2020-11-17 广州燃石医学检验所有限公司 一种基于二代测序的同时检测微卫星位点稳定性和基因组变化的方法
WO2019108807A1 (en) * 2017-12-01 2019-06-06 Personal Genome Diagnositics Inc. Process for microsatellite instability detection

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023018026A1 (ko) * 2021-08-10 2023-02-16 (주)디엑솜 현미부수체 지역의 서열 길이의 최대값과 최소값의 차이를 이용한 현미부수체 불안정성 진단방법
WO2023018024A1 (ko) * 2021-08-10 2023-02-16 (주)디엑솜 현미부수체 지역의 서열 길이의 변화율을 이용한 현미부수체 불안정성 진단방법
KR20230023276A (ko) * 2021-08-10 2023-02-17 (주)디엑솜 현미부수체 지역의 서열 길이의 변화율을 이용한 현미부수체 불안정성 진단방법

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Publication number Publication date
BR112021004763A2 (pt) 2021-08-03
SG11202102528UA (en) 2021-04-29
EP3850111A1 (en) 2021-07-21
IL281417A (en) 2021-04-29
CA3112562A1 (en) 2020-03-19
EP3850111A4 (en) 2022-06-29
JP2022500764A (ja) 2022-01-04
US20210358569A1 (en) 2021-11-18
WO2020056347A1 (en) 2020-03-19
AU2019339511A1 (en) 2021-05-13
CN112955570A (zh) 2021-06-11
JP7514224B2 (ja) 2024-07-10
CN112955570B (zh) 2025-01-21

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Patent event date: 20210409

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