JP7490576B2 - 訓練された統計モデルを使用するマルチモーダル予測のための方法および装置 - Google Patents

訓練された統計モデルを使用するマルチモーダル予測のための方法および装置 Download PDF

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JP7490576B2
JP7490576B2 JP2020566792A JP2020566792A JP7490576B2 JP 7490576 B2 JP7490576 B2 JP 7490576B2 JP 2020566792 A JP2020566792 A JP 2020566792A JP 2020566792 A JP2020566792 A JP 2020566792A JP 7490576 B2 JP7490576 B2 JP 7490576B2
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エム. ロスバーグ、ジョナサン
リッヒェンシュタイン、ヘンリ
エーザー、ウムット
マイヤー、マイケル
ヘルナンデス、メアリーレンズ
シュー、ティアン
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JP2020566792A 2018-05-30 2019-05-08 訓練された統計モデルを使用するマルチモーダル予測のための方法および装置 Active JP7490576B2 (ja)

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US201862678083P 2018-05-30 2018-05-30
US201862678094P 2018-05-30 2018-05-30
US62/678,094 2018-05-30
US62/678,083 2018-05-30
PCT/US2019/031260 WO2019231624A2 (en) 2018-05-30 2019-05-08 Methods and apparatus for multi-modal prediction using a trained statistical model

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Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201904887D0 (en) * 2019-04-05 2019-05-22 Lifebit Biotech Ltd Lifebit al
JP7332238B2 (ja) * 2020-03-10 2023-08-23 エスアールアイ インターナショナル タスク固有のデータ利用のための物理学により誘導されたディープマルチモーダル埋め込みのための方法及び装置
CN111540405B (zh) * 2020-04-29 2023-07-07 新疆大学 一种基于快速网络嵌入的疾病基因预测方法
CN111627515B (zh) * 2020-05-29 2023-07-18 上海商汤智能科技有限公司 药物推荐方法、装置、电子设备及介质
WO2022006676A1 (en) * 2020-07-09 2022-01-13 Mcmaster University Machine learning prediction of biological effect in multicellular animals from microorganism transcriptional fingerprint patterns in non-inhibitory chemical challenge
CN111950295A (zh) * 2020-08-10 2020-11-17 北京嘀嘀无限科技发展有限公司 一种训练自然语言处理模型的方法和系统
CN112151127A (zh) * 2020-09-04 2020-12-29 牛张明 基于分子语义向量的无监督学习药物虚拟筛选方法和系统
KR20230137869A (ko) * 2020-09-25 2023-10-05 리누스 헬스 인코포레이티드 기계 학습 보조 인지 평가 및 치료를 위한 시스템들 및 방법들
US11756572B2 (en) 2020-12-02 2023-09-12 Google Llc Self-supervised speech representations for fake audio detection
CN112700277B (zh) * 2020-12-30 2024-05-28 北京爱笔科技有限公司 用户行为数据的处理方法和多行为序列转化模型训练方法
US12579111B2 (en) * 2020-12-31 2026-03-17 International Business Machines Corporation Cross-domain structural mapping in machine learning processing
CN112862727B (zh) * 2021-03-16 2023-06-23 上海壁仞智能科技有限公司 一种跨模态图像转换方法及装置
CN113223655B (zh) * 2021-05-07 2023-05-12 西安电子科技大学 基于变分自编码器的药物-疾病关联预测方法
JP7674636B2 (ja) * 2021-09-27 2025-05-12 オムロン株式会社 モデル生成方法、データ提示方法、データ生成方法、推定方法、モデル生成装置、データ提示装置、データ生成装置、及び推定装置
CN113869417B (zh) * 2021-09-28 2025-11-14 清华大学 基于自监督和多模态的基因数据模型训练方法及装置
CN113987345A (zh) * 2021-10-27 2022-01-28 北京百度网讯科技有限公司 数据处理的方法、装置、设备、存储介质及程序产品
CN114049930B (zh) * 2021-11-12 2024-07-16 东南大学 一种基于异质网络表示学习的中药药方重定位方法
CN114429787B (zh) * 2021-12-30 2023-04-18 北京百度网讯科技有限公司 组学数据处理方法、装置、电子设备和存储介质
CN114334038B (zh) * 2021-12-31 2024-05-14 杭州师范大学 一种基于异质网络嵌入模型的疾病药物预测方法
CN114613450B (zh) * 2022-03-09 2025-09-19 平安科技(深圳)有限公司 药物分子的性质预测方法、装置、存储介质及计算机设备
CN114626480B (zh) * 2022-03-22 2024-12-13 国网智能电网研究院有限公司 多源异构数据特征提取装置、方法、存储介质及电子设备
WO2023193935A1 (en) * 2022-04-08 2023-10-12 NEC Laboratories Europe GmbH Method and system for predicting gene expression perturbations
KR102841093B1 (ko) * 2022-04-18 2025-07-31 한양대학교 산학협력단 모달리티의 고유 특성을 보존하는 멀티미디어 추천 방법 및 시스템
CN114792573B (zh) * 2022-04-18 2023-02-28 北京百度网讯科技有限公司 药物联用的效果预测方法、模型训练方法、装置及设备
CN118158425A (zh) * 2022-11-30 2024-06-07 华为技术有限公司 图像压缩系统、图像处理方法和编解码方法及电子设备
CN115587257B (zh) * 2022-12-13 2023-04-07 阿里巴巴(中国)有限公司 模型超参数优化方法、存储介质和电子设备
KR20240108318A (ko) * 2022-12-30 2024-07-09 건국대학교 글로컬산학협력단 머신 러닝 기반 메타 분석을 이용하여 계산된 일치된 가중치 연결 점수의 앙상블에 의한 신약 재창출 후보군 예측 방법 및 장치
CN116524997B (zh) * 2023-05-04 2024-07-16 电子科技大学 基于经典-量子混合神经网络实现药物相互作用结果的预测系统
CN116244484B (zh) * 2023-05-11 2023-08-08 山东大学 一种面向不平衡数据的联邦跨模态检索方法及系统
WO2024263011A1 (ko) * 2023-06-23 2024-12-26 주식회사 엘지 경영개발원 멀티태스킹 모델 학습 방법 및 이를 기초로 학습된 머신러닝 모델을 이용한 멀티태스킹 수행 방법
WO2025015037A1 (en) * 2023-07-10 2025-01-16 Symphony Diagnostics, Inc. Systems and methods for animal health assessment, surveillance, and enhancement
CN117133436A (zh) * 2023-10-17 2023-11-28 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) 基于多源数据融合的药物疾病关联预测方法、装置及设备
WO2025105524A1 (ko) * 2023-11-15 2025-05-22 엘지전자 주식회사 인공 지능 서버 및 그의 동작 방법
CN118352085B (zh) * 2024-06-14 2024-09-17 之江实验室 基于多时间点多模态脑影像数据的脑疾病病程预测系统
WO2026016189A1 (en) * 2024-07-19 2026-01-22 Antinous Technology Company Limited Methylation transformer for cancer detection
WO2026076576A1 (en) * 2024-10-08 2026-04-16 Huawei Technologies Co., Ltd. Devices and methods for in-network learning for dynamic wireless networks
CN119830148B (zh) * 2024-11-14 2025-10-28 安徽理工大学 基于自监督空间学习的跨模态轴承故障诊断方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000310997A (ja) 1999-03-09 2000-11-07 Matsushita Electric Ind Co Ltd 連結型音声合成のための単位重複領域の識別方法および連結型音声合成方法
JP2010152751A (ja) 2008-12-25 2010-07-08 Nec Corp 統計モデル学習装置、統計モデル学習方法、およびプログラム
JP2013211616A (ja) 2012-03-30 2013-10-10 Sony Corp 端末装置、端末制御方法、プログラム、および情報処理システム
US20160170982A1 (en) 2014-12-16 2016-06-16 Yahoo! Inc. Method and System for Joint Representations of Related Concepts
WO2017122785A1 (en) 2016-01-15 2017-07-20 Preferred Networks, Inc. Systems and methods for multimodal generative machine learning
US20190197366A1 (en) 2016-09-05 2019-06-27 Kheiron Medical Technologies Ltd Multi-modal medical image processing

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107545151B (zh) * 2017-09-01 2020-10-16 中南大学 一种基于低秩矩阵填充的药物重定位方法

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000310997A (ja) 1999-03-09 2000-11-07 Matsushita Electric Ind Co Ltd 連結型音声合成のための単位重複領域の識別方法および連結型音声合成方法
JP2010152751A (ja) 2008-12-25 2010-07-08 Nec Corp 統計モデル学習装置、統計モデル学習方法、およびプログラム
JP2013211616A (ja) 2012-03-30 2013-10-10 Sony Corp 端末装置、端末制御方法、プログラム、および情報処理システム
US20160170982A1 (en) 2014-12-16 2016-06-16 Yahoo! Inc. Method and System for Joint Representations of Related Concepts
WO2017122785A1 (en) 2016-01-15 2017-07-20 Preferred Networks, Inc. Systems and methods for multimodal generative machine learning
US20190197366A1 (en) 2016-09-05 2019-06-27 Kheiron Medical Technologies Ltd Multi-modal medical image processing
JP2019530116A (ja) 2016-09-05 2019-10-17 ケイロン メディカル テクノロジーズ リミテッド マルチモーダル医用画像処理

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
NAPOLITANO Francesco et al.,Drug repositioning: a machine-learning approach through data integration,Journal of Cheminformatics volume 5, Article number: 30 (2013),英国,BIOMED CENTRAL LTD, UK,2013年06月22日,volume 5, Article number: 30 (2013),pp.1-9,[令和 5年4月24日検索],インターネット <URL:https://jcheminf.biomedcentral.com/counter/pdf/10.1186/1758-2946-5-30.pdf>,ISSN: 1758-2946、DOI: https://doi.org/10.1186/1758-2946-5-30,
Zhang, Ping et al.,Towards Drug Repositioning: A Unified Computational Framework for Integrating Multiple Aspects of Drug Similarity and Disease Similarity,AMIA Annual Symposium Proceedings 2014,米国,AMIA,2014年11月14日,pp.1258-1267,[令和 5年4月24日検索],インターネット <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419869/>

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CA3100065A1 (en) 2019-12-05
EP3803884A2 (en) 2021-04-14
WO2019231624A3 (en) 2020-03-19
AU2019276730A1 (en) 2020-12-10
KR20210018333A (ko) 2021-02-17
MX2020012899A (es) 2021-02-26
BR112020023429A2 (pt) 2021-02-23
JP2021526259A (ja) 2021-09-30
WO2019231624A2 (en) 2019-12-05
CN112513990A (zh) 2021-03-16

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