JP7482872B2 - 速度変化を使用したlvad患者の高血圧の検出 - Google Patents
速度変化を使用したlvad患者の高血圧の検出 Download PDFInfo
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Description
Claims (15)
- 埋め込み型血液ポンプを含む、心室補助装置を有する患者に適用可能に構成された高血圧検出システムの作動方法であって、
前記高血圧検出システムは、コントローラを備え、
前記コントローラは、
第1の期間中に第1のポンプ設定速度で前記埋め込み型血液ポンプを動作させることと、
前記第1の期間中、第1の流量脈動性および第1の電流脈動性からなる群からの少なくとも1つを測定することと、
前記第1の期間の後の第2の期間中に前記第1のポンプ設定速度を第2のポンプ設定速度に下げることと、
前記第2の期間中、第2の流量脈動性および第2の電流脈動性からなる群からの少なくとも1つを測定することと、
前記第1の期間中の前記第1のポンプ設定速度での前記第1の流量脈動性および前記第1の電流脈動性からなる群からの少なくとも1つと比較して、前記第2のポンプ設定速度での前記第2の期間中に前記第2の流量脈動性および前記第2の電流脈動性からなる群からの少なくとも1つが増加しているか否かを判定することと
を実行するように構成され、
前記第1の期間中に測定された脈動性と比較して前記第2の期間中に測定された前記脈動性が増加していることは、前記患者の高血圧に対応する、
方法。 - 前記コントローラは、
前記第1の期間中の前記第1のポンプ設定速度での前記第1の流量脈動性および前記第1の電流脈動性からなる群からの少なくとも1つと比較して、前記第2のポンプ設定速度での前記第2の期間中に前記第2の流量脈動性および前記第2の電流脈動性からなる群からの少なくとも1つが増加したと判定された場合、高血圧の存在を示すアラートを生成すること
をさらに実行する、
請求項1に記載の方法。 - 前記第2のポンプ設定速度は、前記第1のポンプ設定速度より少なくとも200rpm低い、
請求項1または2に記載の方法。 - 前記第2の期間は前記第1の期間よりも短い、
請求項1~3のうちいずれか1つに記載の方法。 - 前記埋め込み型血液ポンプの連続動作中、前記第1の期間および前記第2の期間は連続している、
請求項1~4のうちいずれか1つに記載の方法。 - 前記第1の期間および前記第2の期間は、所定の間隔で周期的である、
請求項5に記載の方法。 - 前記埋め込み型血液ポンプは遠心流血液ポンプである、
請求項1~5のうちいずれか1つに記載の方法。 - 前記埋め込み型血液ポンプは軸流血液ポンプである、
請求項1~5のうちいずれか1つに記載の方法。 - 前記コントローラは、
第1の流量脈動性および第2の流量脈動性を測定する、
請求項1に記載の方法。 - 前記コントローラは、
前記第1の電流脈動性および前記第2の電流脈動性を測定する、
請求項1に記載の方法。 - 心室補助装置を有する患者の高血圧を検出するためのシステムであって、前記心室補助装置が埋め込み型血液ポンプを含み、前記システムが、
前記埋め込み型血液ポンプと通信するコントローラであって、処理回路を含むプロセッサを有するコントローラを備え、
前記処理回路が、
前記埋め込み型血液ポンプを第1の期間中に第1のポンプ設定速度で動作させ、
前記第1の期間中、第1の流量の最小値および第1の電流の最小値からなる群からの少なくとも1つを測定し、
前記第1のポンプ設定速度を前記第1の期間の後の第2の期間中に第2のポンプ設定速度に下げ、
第2の期間中、第2の流量の最小値および第2の電流の最小値からなる群からの少なくとも1つを測定し、
前記第2の流量の最小値および前記第2の電流の最小値からなる群からの少なくとも1つが、前記第2のポンプ設定速度で第2の期間中に所定量を超えて減少する場合、
前記第2のポンプ設定速度を前記第1のポンプ設定速度に上げる、または
患者の高血圧を示すフラグまたはアラートを生成する
ように構成された、システム。 - 前記コントローラは、前記第2の流量の最小値および前記第2の電流の最小値からなる群からの前記少なくとも1つが、所定の量を超えて、前記第2のポンプ設定速度で前記第2の期間中に減少した場合に、高血圧の存在を示すアラートを生成するように構成される、
請求項11に記載のシステム。 - 前記第2のポンプ設定速度は、
前記第1のポンプ設定速度よりも少なくとも200rpm低い、
請求項11または12に記載のシステム。 - 前記第2の期間は、前記第1の期間よりも短い、
請求項11~13のうちいずれか1つに記載のシステム。 - 前記埋め込み型血液ポンプの連続動作中、前記第1の期間および前記第2の期間は連続している、
請求項11~14のうちいずれか1つに記載のシステム。
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US16/775,982 US11666281B2 (en) | 2019-02-28 | 2020-01-29 | Detection of hypertension in LVAD patients using speed change |
US16/775,982 | 2020-01-29 | ||
PCT/US2020/017587 WO2020176242A1 (en) | 2019-02-28 | 2020-02-11 | Detection of hypertension in lvad patients using speed change |
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US11666281B2 (en) | 2023-06-06 |
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JP2022522090A (ja) | 2022-04-14 |
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