JP7475686B2 - Ｃａｒ－ｔ細胞及び自己免疫疾患 - Google Patents

Ｃａｒ－ｔ細胞及び自己免疫疾患 Download PDF

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JP7475686B2
JP7475686B2 JP2020542604A JP2020542604A JP7475686B2 JP 7475686 B2 JP7475686 B2 JP 7475686B2 JP 2020542604 A JP2020542604 A JP 2020542604A JP 2020542604 A JP2020542604 A JP 2020542604A JP 7475686 B2 JP7475686 B2 JP 7475686B2
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JPWO2019157461A5 (https=
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エー．ブルーストーン ジェフリー
ラフィン キャロライン
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University of California San Diego UCSD
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C12N5/0602—Vertebrate cells
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    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
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    • C07K2319/00—Fusion polypeptide
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JP2020542604A 2018-02-11 2019-02-11 Ｃａｒ－ｔ細胞及び自己免疫疾患 Active JP7475686B2 (ja)

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JP2023223121A JP2024038225A (ja) 2018-02-11 2023-12-28 Ｃａｒ－ｔ細胞及び自己免疫疾患

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US201862629103P 2018-02-11 2018-02-11
US62/629,103 2018-02-11
PCT/US2019/017532 WO2019157461A1 (en) 2018-02-11 2019-02-11 Car-t cells and autoimmune diseases

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US (1) US12421302B2 (https=)
EP (1) EP3749778A4 (https=)
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KR (1) KR102795055B1 (https=)
CN (2) CN118878696A (https=)
AU (2) AU2019216989B2 (https=)
BR (1) BR112020016030A2 (https=)
CA (1) CA3090891A1 (https=)
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AU2021219886B2 (en) 2020-02-13 2025-01-23 Imunopharm Technology Co., Ltd. Optimization of chimeric antigen receptor
WO2021226589A1 (en) * 2020-05-08 2021-11-11 The University Of Kansas Immunomagnetic compositions for the ph-specific capture of extracellular vesicles
US20230381228A1 (en) * 2020-10-29 2023-11-30 The Regents Of The University Of California Anti-dpp6 chimeric antigen receptor bearing regulatory t cells
CA3226798A1 (en) * 2021-07-29 2023-02-02 James MATTHAEI Synovial extracellular matrix-specific chimeric antigen receptor for targeting regulatory t cells to treat autoimmune diseases
GB202202842D0 (en) * 2022-03-01 2022-04-13 Belgian Volition Srl Chimeric antigen receptor T-cell treatments targeted to chromatin fragments and extracellular traps
CA3267341A1 (en) * 2022-09-19 2024-03-28 Sonoma Biotherapeutics, Inc. Specific chimeric antigen receptors for a citrullinated antigen to target regulatory T lymphocytes for the treatment of hidradenitis suppurativa
WO2024254286A2 (en) * 2023-06-07 2024-12-12 Sonoma Biotherapeutics, Inc. Methods of detecting citrullinated proteins
WO2025090985A1 (en) * 2023-10-27 2025-05-01 Duke University Compositions comprising chimeric antigen receptors targeting citrullinated vimentin and methods of use thereof
WO2026008994A1 (en) 2024-07-04 2026-01-08 Quell Therapeutics Limited Expression construct
WO2026020171A2 (en) * 2024-07-19 2026-01-22 Aera Therapeutics, Inc. Chimeric antigen receptor constructs

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WO2017100428A1 (en) 2015-12-09 2017-06-15 Memorial Sloan Kettering Cancer Center Immune cell compositions and methods of using same

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AU2015209263A1 (en) * 2014-01-24 2016-07-28 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-NY-BR-1 polypeptides, proteins, and chimeric antigen receptors
WO2016033331A1 (en) * 2014-08-28 2016-03-03 Bioatla, Llc Conditionally active chimeric antigen receptors for modified t-cells
EP4074731A1 (en) * 2015-11-04 2022-10-19 City of Hope Chimeric antigen receptors targeting her2

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US20160159922A1 (en) 2013-07-24 2016-06-09 Vilara Ab Novel Antibodies for the Diagnosis and Treatment of Rheumatoid Arthritis
WO2017100428A1 (en) 2015-12-09 2017-06-15 Memorial Sloan Kettering Cancer Center Immune cell compositions and methods of using same

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Arthritis and Rheumatology，2014年，66，1712-1722
Expert Opinion on Biological Therapy，2017年，17，961-978
frontiers in Oncology，2014年，4，Article 209
Journal of Immunology，2016年，196 (1_Suppl)，210.19.
Nature Reviews Rheumatology，2017年，13，525-537

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CA3090891A1 (en) 2019-08-15
SG11202007370RA (en) 2020-08-28
US12421302B2 (en) 2025-09-23
AU2025271320A1 (en) 2025-12-18
WO2019157461A1 (en) 2019-08-15
JP2021513337A (ja) 2021-05-27
JP2024038225A (ja) 2024-03-19
AU2019216989A1 (en) 2020-09-24
CL2020002066A1 (es) 2021-01-04
EP3749778A4 (en) 2021-11-10
BR112020016030A2 (pt) 2020-12-08
AU2019216989B2 (en) 2025-08-28
KR20200130292A (ko) 2020-11-18
CN111954684A (zh) 2020-11-17
KR102795055B1 (ko) 2025-04-11
US20200399355A1 (en) 2020-12-24
EA202091918A1 (ru) 2020-12-17
IL276445A (en) 2020-09-30
CN111954684B (zh) 2024-05-07

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