JP7466907B2 - 広域スペクトルの抗ウイルス治療のための組成物及び方法 - Google Patents

広域スペクトルの抗ウイルス治療のための組成物及び方法 Download PDF

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JP7466907B2
JP7466907B2 JP2020542534A JP2020542534A JP7466907B2 JP 7466907 B2 JP7466907 B2 JP 7466907B2 JP 2020542534 A JP2020542534 A JP 2020542534A JP 2020542534 A JP2020542534 A JP 2020542534A JP 7466907 B2 JP7466907 B2 JP 7466907B2
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mers
virus
cells
viral
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JPWO2019079339A5 (https=
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JP2021500400A (ja
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ユアン，シュオフェン
チャン，フック・ウー・ジャスパー
チュ，ヒン
ラウ，ジョンソン・ユ‐ナム
ユエン，クウォック・ユン
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Versitech Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2020542534A 2017-10-18 2018-10-16 広域スペクトルの抗ウイルス治療のための組成物及び方法 Active JP7466907B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762573933P 2017-10-18 2017-10-18
US62/573,933 2017-10-18
PCT/US2018/056138 WO2019079339A1 (en) 2017-10-18 2018-10-16 COMPOSITIONS AND METHODS FOR BROAD SPECTRUM ANTIVIRAL THERAPY

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JP2021500400A JP2021500400A (ja) 2021-01-07
JPWO2019079339A5 JPWO2019079339A5 (https=) 2023-02-03
JP2021500400A5 JP2021500400A5 (https=) 2023-02-03
JP7466907B2 true JP7466907B2 (ja) 2024-04-15

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US (1) US12213955B2 (https=)
EP (1) EP3697404B1 (https=)
JP (1) JP7466907B2 (https=)
CN (1) CN111886008B (https=)
TW (1) TWI860281B (https=)
WO (1) WO2019079339A1 (https=)

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WO2018089306A1 (en) 2016-11-10 2018-05-17 Oyagen, Inc. Methods of treating and inhibiting ebola virus infection
CN112789925B (zh) * 2019-06-27 2023-06-02 Oppo广东移动通信有限公司 用于指示空间关系信息的方法和设备
US11738025B2 (en) 2020-02-04 2023-08-29 Oyagen, Inc. Method for treating coronavirus infections
AU2021235899A1 (en) * 2020-03-08 2022-10-13 Humanigen, Inc. Methods for treating coronavirus infection and resulting inflammation-induced lung injury
US11628165B1 (en) * 2020-03-25 2023-04-18 Helen Feng Method of boosting immune system against viral infection
ES2862462B2 (es) * 2020-04-06 2023-04-27 Servicio Andaluz De Salud Compuestos para la profilaxis y/o el tratamiento del sindrome de dificultad respiratoria aguda
WO2021211738A1 (en) * 2020-04-15 2021-10-21 Sanford Burnham Prebys Medical Discovery Institute Methods and compositions for antiviral treatment
WO2021226479A1 (en) * 2020-05-07 2021-11-11 The Regents Of The University Of California Inhaled statins for treatment of viral respiratory diseases
BR112022023746A2 (pt) * 2020-05-22 2023-02-07 Alberto Riveros Carlos Sistema, método e uso de um determinado medicamento para reduzir a replicação viral na mucosa das vias aéreas
WO2021249240A1 (zh) * 2020-06-11 2021-12-16 养生堂有限公司 Palovarotene在抗hbv病毒治疗中的用途
US20240131036A1 (en) * 2020-07-02 2024-04-25 The Uab Research Foundation Compositions and methods of treating conditions
CN112390731B (zh) * 2020-11-16 2022-11-25 成都大学 一种具有多靶点的维甲酸类衍生物及其制备方法与应用
US11998562B2 (en) 2021-01-25 2024-06-04 University Of South Florida Ophthalmological formulations for the prevention of a coronavirus infection
CN117062611A (zh) 2021-01-26 2023-11-14 惠和生物技术(上海)有限公司 嵌合抗原受体（car）构建体和表达car构建体的nk细胞
US20220378727A1 (en) * 2021-05-14 2022-12-01 The University Of Hong Kong Dry powder formulations of tamibarotene for pulmonary and intranasal delivery
CN116891497B (zh) * 2022-04-02 2025-12-16 上海旭成医药科技有限公司 视黄酸受体激动剂、其制备方法、中间体、药物组合物和应用
WO2023210634A1 (ja) * 2022-04-28 2023-11-02 国立大学法人東海国立大学機構 拡張障害を伴う心不全の治療用医薬組成物
CN119454680B (zh) * 2024-12-06 2025-06-17 华南农业大学 贝沙罗汀在制备抗prrsv或治疗猪蓝耳病的药物中的应用
CN121177272A (zh) * 2025-11-10 2025-12-23 北京市农林科学院 化合物am580在预防或治疗塞内卡病毒病中的用途

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WO2015138354A1 (en) 2014-03-10 2015-09-17 Cornell University Combination therapy for head and neck cancer
JP2017508737A (ja) 2014-02-18 2017-03-30 チルドレンズ ホスピタル ロサンゼルス 好中球減少症の治療用の組成物及び方法

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US7341717B2 (en) 2001-04-13 2008-03-11 Gpc Biotech Ag Therapeutic targets for treatment of HCV infections, methods of treating HCV infections and compounds useful therefor
US20060151574A1 (en) * 2002-11-29 2006-07-13 Gpc Biotech Ag Formulations useful against hepatitis C virus infections
WO2005120479A1 (en) * 2004-06-09 2005-12-22 Gpc Biotech Ag Use of selenium or a selenium salt and a retinoid acid or a retinoid in the treatment of viral hepatitis c
EP1886685A1 (en) 2006-08-11 2008-02-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods, uses and compositions for modulating replication of hcv through the farnesoid x receptor (fxr) activation or inhibition
ES2609825T3 (es) * 2007-01-18 2017-04-24 Evolva Sa 1,3-Dioxanos sustituidos útiles como moduladores de PPAR
CN104662036B (zh) * 2012-04-25 2018-11-09 华辉安健（北京）生物科技有限公司 乙肝肝炎病毒功能性受体的组成以及相关应用
US20150290235A1 (en) * 2012-11-23 2015-10-15 Ab Science Use of small molecule inhibitors/activators in combination with (deoxy)nucleoside or (deoxy)nucleotide analogs for treatment of cancer and hematological malignancies or viral infections
WO2018054891A1 (en) 2016-09-20 2018-03-29 Ruprecht-Karls-Universität Compounds and combinations thereof for preventing and/or treating hbv and/or hdv infections

Patent Citations (2)

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JP2017508737A (ja) 2014-02-18 2017-03-30 チルドレンズ ホスピタル ロサンゼルス 好中球減少症の治療用の組成物及び方法
WO2015138354A1 (en) 2014-03-10 2015-09-17 Cornell University Combination therapy for head and neck cancer

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TWI860281B (zh) 2024-11-01
US20200338032A1 (en) 2020-10-29
EP3697404B1 (en) 2025-03-26
CN111886008A (zh) 2020-11-03
EP3697404A1 (en) 2020-08-26
JP2021500400A (ja) 2021-01-07
TW201927293A (zh) 2019-07-16
WO2019079339A1 (en) 2019-04-25
US12213955B2 (en) 2025-02-04
CN111886008B (zh) 2024-05-31
EP3697404A4 (en) 2021-07-21

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