JP7455828B2 - 実質的に平坦な底部を有するポリマーバイアル、及びそのようなポリマーバイアルを製造する射出延伸ブロー成形方法 - Google Patents

実質的に平坦な底部を有するポリマーバイアル、及びそのようなポリマーバイアルを製造する射出延伸ブロー成形方法 Download PDF

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JP7455828B2
JP7455828B2 JP2021525665A JP2021525665A JP7455828B2 JP 7455828 B2 JP7455828 B2 JP 7455828B2 JP 2021525665 A JP2021525665 A JP 2021525665A JP 2021525665 A JP2021525665 A JP 2021525665A JP 7455828 B2 JP7455828 B2 JP 7455828B2
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injection
solution
mold
vial
drugs
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JP2022507207A5 (https=
JP2022507207A (ja
JPWO2020102434A5 (https=
Inventor
ユージン・サズヴィッチ
ケネス・ウェイド・ケリー
マーティン・バルタザー
アダム・ブリーランド
トーマス・イー・フィスク
デビッド・ヘントン
ブライアン・マウラー
アーマッド・タハ
クリストファー・ヴァイカルト
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SiO2 Medical Products LLC
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SIO2 Medical Products Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1468—Containers characterised by specific material properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00—Rigid or semi-rigid containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material or by deep-drawing operations performed on sheet material
    • B65D1/02—Bottles or similar containers with necks or like restricted apertures, designed for pouring contents
    • B65D1/0223—Bottles or similar containers with necks or like restricted apertures, designed for pouring contents characterised by shape
    • B65D1/0261—Bottom construction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/0005—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor characterised by the material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/02—Combined blow-moulding and manufacture of the preform or the parison
    • B29C49/06—Injection blow-moulding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/08—Biaxial stretching during blow-moulding
    • B29C49/10—Biaxial stretching during blow-moulding using mechanical means for prestretching
    • B29C49/12—Stretching rods
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00—Rigid or semi-rigid containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material or by deep-drawing operations performed on sheet material
    • B65D1/02—Bottles or similar containers with necks or like restricted apertures, designed for pouring contents
    • B65D1/0223—Bottles or similar containers with necks or like restricted apertures, designed for pouring contents characterised by shape
    • B65D1/0261—Bottom construction
    • B65D1/0276—Bottom construction having a continuous contact surface, e.g. Champagne-type bottom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/02—Combined blow-moulding and manufacture of the preform or the parison
    • B29C2049/023—Combined blow-moulding and manufacture of the preform or the parison using inherent heat of the preform, i.e. 1 step blow moulding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/42—Component parts, details or accessories; Auxiliary operations
    • B29C49/48—Moulds
    • B29C2049/4879—Moulds characterised by mould configurations
    • B29C2049/4881—Moulds characterised by mould configurations having a mandrel or core e.g. two mould halves with a core in-between
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/42—Component parts, details or accessories; Auxiliary operations
    • B29C49/48—Moulds
    • B29C2049/4879—Moulds characterised by mould configurations
    • B29C2049/4882—Mould cavity geometry
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/42—Component parts, details or accessories; Auxiliary operations
    • B29C49/48—Moulds
    • B29C2049/4879—Moulds characterised by mould configurations
    • B29C2049/4892—Mould halves consisting of an independent main and bottom part
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/38—Polymers of cycloalkenes, e.g. norbornene or cyclopentene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/712—Containers; Packaging elements or accessories, Packages
    • B29L2031/7158—Bottles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/712—Containers; Packaging elements or accessories, Packages
    • B29L2031/7158—Bottles
    • B29L2031/716—Bottles of the wide mouth type, i.e. the diameters of the bottle opening and its body are substantially identical
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00—Rigid or semi-rigid containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material or by deep-drawing operations performed on sheet material
    • B65D1/09—Ampoules

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Ceramic Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)
  • Blow-Moulding Or Thermoforming Of Plastics Or The Like (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2021525665A 2018-11-13 2019-11-13 実質的に平坦な底部を有するポリマーバイアル、及びそのようなポリマーバイアルを製造する射出延伸ブロー成形方法 Active JP7455828B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862760542P 2018-11-13 2018-11-13
US62/760,542 2018-11-13
PCT/US2019/061293 WO2020102434A2 (en) 2018-11-13 2019-11-13 Polymer vials with substantially flat bottoms and injection stretch blow molding methods for making the same

Publications (4)

Publication Number Publication Date
JP2022507207A JP2022507207A (ja) 2022-01-18
JP2022507207A5 JP2022507207A5 (https=) 2022-11-21
JPWO2020102434A5 JPWO2020102434A5 (https=) 2022-11-21
JP7455828B2 true JP7455828B2 (ja) 2024-03-26

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JP2021525665A Active JP7455828B2 (ja) 2018-11-13 2019-11-13 実質的に平坦な底部を有するポリマーバイアル、及びそのようなポリマーバイアルを製造する射出延伸ブロー成形方法

Country Status (6)

Country Link
US (2) US12478553B2 (https=)
EP (1) EP3880431B1 (https=)
JP (1) JP7455828B2 (https=)
CN (1) CN113853290B (https=)
CA (1) CA3119648A1 (https=)
WO (1) WO2020102434A2 (https=)

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WO2022211865A1 (en) * 2021-03-31 2022-10-06 Sio2 Medical Products, Inc. Atomic layer deposition coated pharmaceutical packaging and improved syringes and vials, e.g. for lyophilized/cold-chain drugs/vaccines
US20230303305A1 (en) * 2020-07-28 2023-09-28 Sio2 Medical Products, Inc. Method and package for reducing the degradation of a drug and/or excipient, e.g. polysorbate stabilizer, in a pharmaceutical product
US20240066146A1 (en) * 2020-12-18 2024-02-29 Sangamo Therapeutics, Inc. Improved pharmaceutical compositions containing adeno-associated viral vector
WO2022232349A1 (en) * 2021-04-28 2022-11-03 Fina Technology, Inc. Low friction isbm bottles
US20240299640A1 (en) 2021-05-11 2024-09-12 Sio2 Medical Products, Inc. Drug Primary Package Having Integrated RFID Tag
CN116730612B (zh) * 2023-07-13 2025-08-01 中国建筑材料科学研究总院有限公司 一种光学玻璃及其制备方法和应用
US20250042595A1 (en) * 2023-08-04 2025-02-06 Canon Kabushiki Kaisha Liquid storage bottle
WO2025101449A1 (en) * 2023-11-09 2025-05-15 Corning Incorporated Designed bottom and flange ring-off breakage of strengthened glass containers via geometrical features

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JP2018514595A (ja) 2015-02-26 2018-06-07 エスアイオーツー・メディカル・プロダクツ・インコーポレイテッド 耐擦り傷性かつ帯電防止性のコーティングを有するシクロオレフィンポリマー容器

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JP2013545504A (ja) 2010-10-06 2013-12-26 アラーガン、インコーポレイテッド ボツリヌス毒素の貯蔵およびその後の取り扱いのためのシステム
JP2018514595A (ja) 2015-02-26 2018-06-07 エスアイオーツー・メディカル・プロダクツ・インコーポレイテッド 耐擦り傷性かつ帯電防止性のコーティングを有するシクロオレフィンポリマー容器

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Publication number Publication date
US12478553B2 (en) 2025-11-25
JP2022507207A (ja) 2022-01-18
WO2020102434A3 (en) 2020-07-23
US20260076872A1 (en) 2026-03-19
CA3119648A1 (en) 2020-05-22
US20220008292A1 (en) 2022-01-13
EP3880431A2 (en) 2021-09-22
WO2020102434A2 (en) 2020-05-22
EP3880431B1 (en) 2024-08-14
CN113853290A (zh) 2021-12-28
CN113853290B (zh) 2024-07-12

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