JP7442141B2 - Ccr2アンタゴニストによる固形腫瘍の治療方法 - Google Patents
Ccr2アンタゴニストによる固形腫瘍の治療方法 Download PDFInfo
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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US201862614923P | 2018-01-08 | 2018-01-08 | |
US62/614,923 | 2018-01-08 | ||
PCT/US2019/012515 WO2019136368A2 (fr) | 2018-01-08 | 2019-01-07 | Procédés de traitement de tumeurs solides au moyen d'antagonistes du ccr2 |
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JP2021509678A JP2021509678A (ja) | 2021-04-01 |
JPWO2019136368A5 JPWO2019136368A5 (fr) | 2022-01-18 |
JP7442141B2 true JP7442141B2 (ja) | 2024-03-04 |
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JP2020537565A Active JP7442141B2 (ja) | 2018-01-08 | 2019-01-07 | Ccr2アンタゴニストによる固形腫瘍の治療方法 |
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US (2) | US11154556B2 (fr) |
EP (1) | EP3737367A4 (fr) |
JP (1) | JP7442141B2 (fr) |
CN (1) | CN112105353B (fr) |
AU (1) | AU2019205784A1 (fr) |
CA (1) | CA3087765A1 (fr) |
IL (1) | IL275898A (fr) |
MA (1) | MA50423A (fr) |
TW (1) | TW201938160A (fr) |
WO (1) | WO2019136368A2 (fr) |
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AR112831A1 (es) | 2017-09-25 | 2019-12-18 | Chemocentryx Inc | Terapia de combinación usando un antagonista del receptor 2 de quimiocina (ccr2) y un inhibidor de pd-1 / pd-l1 |
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US11154556B2 (en) | 2021-10-26 |
US20220241290A1 (en) | 2022-08-04 |
EP3737367A4 (fr) | 2022-11-09 |
JP2021509678A (ja) | 2021-04-01 |
IL275898A (en) | 2020-08-31 |
AU2019205784A1 (en) | 2020-07-30 |
TW201938160A (zh) | 2019-10-01 |
CA3087765A1 (fr) | 2019-07-11 |
CN112105353A (zh) | 2020-12-18 |
MA50423A (fr) | 2020-08-26 |
EP3737367A2 (fr) | 2020-11-18 |
US20190209573A1 (en) | 2019-07-11 |
WO2019136368A2 (fr) | 2019-07-11 |
CN112105353B (zh) | 2024-04-19 |
WO2019136368A3 (fr) | 2020-04-16 |
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