JP7418026B2 - マイクロ流体粒子分離強化の方法およびその装置 - Google Patents

マイクロ流体粒子分離強化の方法およびその装置 Download PDF

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Publication number
JP7418026B2
JP7418026B2 JP2021537100A JP2021537100A JP7418026B2 JP 7418026 B2 JP7418026 B2 JP 7418026B2 JP 2021537100 A JP2021537100 A JP 2021537100A JP 2021537100 A JP2021537100 A JP 2021537100A JP 7418026 B2 JP7418026 B2 JP 7418026B2
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particles
hydrofoil
arcuate
downstream
separation
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Japanese (ja)
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JP2022526064A (ja
JP2022526064A5 (enExample
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オズカヤー，ガーハン
イルディリム，エンダー
ゾール，オッジ
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Mikro Biyosistemler Elektronik Sanayi ve Ticaret AS
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Mikro Biyosistemler Elektronik Sanayi ve Ticaret AS
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652—Sorting or classification of particles or molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0883—Serpentine channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1028—Sorting particles

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
JP2021537100A 2018-12-28 2019-05-03 マイクロ流体粒子分離強化の方法およびその装置 Active JP7418026B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
TRPCT/TR2018/050932 2018-12-28
PCT/TR2018/050932 WO2020139210A1 (en) 2018-12-28 2018-12-28 A method of microfluidic particle separation enhancement and the device thereof
PCT/TR2019/050295 WO2020139218A1 (en) 2018-12-28 2019-05-03 A method of microfluidic particle separation enhancement and the device thereof

Publications (3)

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JP2022526064A JP2022526064A (ja) 2022-05-23
JP2022526064A5 JP2022526064A5 (enExample) 2023-05-17
JP7418026B2 true JP7418026B2 (ja) 2024-01-19

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US (1) US12036553B2 (enExample)
EP (1) EP3873669A4 (enExample)
JP (1) JP7418026B2 (enExample)
KR (1) KR102747514B1 (enExample)
AU (1) AU2019414140B2 (enExample)
IL (1) IL284275B2 (enExample)
SG (1) SG11202106718QA (enExample)
WO (2) WO2020139210A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102474060B1 (ko) * 2020-10-14 2022-12-05 한국과학기술연구원 미세유체칩 유동에 의한 세포입자의 크기별 분리 장치와 방법
EP4265336A1 (en) * 2020-12-21 2023-10-25 IHI Corporation Solid-liquid separation device and solid-liquid separation system

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001527220A (ja) 1997-12-24 2001-12-25 シーフィード 一体型流体操作カートリッジ
JP2008137003A (ja) 2006-11-30 2008-06-19 Palo Alto Research Center Inc 流体内の粒子を処理する装置及びらせん形分離装置を形成する方法
JP2009530400A (ja) 2006-03-23 2009-08-27 ヴェロシス，インク． マイクロチャネルプロセス技術を用いてスチレンを作るためのプロセス
WO2009129586A1 (en) 2008-04-24 2009-10-29 Filtra Limited Centrifugal separator
JP2016537198A (ja) 2013-10-25 2016-12-01 トラァイロバイト イノヴェイション アクティーゼルスカブ 流体濾過装置及びアセンブリー

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1585583B1 (en) * 2002-10-23 2010-04-07 The Trustees of Princeton University Method for continuous particle separation using obstacle arrays asymmetrically aligned to fields
US20070059719A1 (en) * 2005-09-15 2007-03-15 Michael Grisham Business methods for prenatal Diagnosis
EP2321055A4 (en) * 2008-07-10 2012-01-18 Steven H Reichenbach METHOD AND DEVICE FOR SORTING PARTICLES USING ASYMMETRIC PARTICLE SHIFT
GB0913523D0 (en) * 2009-08-03 2009-09-16 Vestfold University College Improved cross flow and counter flow fluid processing devices
US9458489B2 (en) * 2010-03-04 2016-10-04 Massachusetts Institute Of Technology Microfluidics sorter for cell detection and isolation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001527220A (ja) 1997-12-24 2001-12-25 シーフィード 一体型流体操作カートリッジ
JP2009530400A (ja) 2006-03-23 2009-08-27 ヴェロシス，インク． マイクロチャネルプロセス技術を用いてスチレンを作るためのプロセス
JP2008137003A (ja) 2006-11-30 2008-06-19 Palo Alto Research Center Inc 流体内の粒子を処理する装置及びらせん形分離装置を形成する方法
WO2009129586A1 (en) 2008-04-24 2009-10-29 Filtra Limited Centrifugal separator
JP2016537198A (ja) 2013-10-25 2016-12-01 トラァイロバイト イノヴェイション アクティーゼルスカブ 流体濾過装置及びアセンブリー

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WO2020139218A1 (en) 2020-07-02
AU2019414140A1 (en) 2021-07-15
US12036553B2 (en) 2024-07-16
IL284275B1 (en) 2024-10-01
JP2022526064A (ja) 2022-05-23
KR20210110307A (ko) 2021-09-07
EP3873669A4 (en) 2021-12-29
EP3873669A1 (en) 2021-09-08
IL284275B2 (en) 2025-02-01
US20220072551A1 (en) 2022-03-10
SG11202106718QA (en) 2021-07-29
KR102747514B1 (ko) 2024-12-31
WO2020139210A1 (en) 2020-07-02
IL284275A (en) 2021-08-31
AU2019414140B2 (en) 2023-07-06

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