JP7384538B2 - カートリッジのための流体チャネル - Google Patents
カートリッジのための流体チャネル Download PDFInfo
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Description
本出願は2018年9月28日付けで出願された米国特許出願第16/146,121号明細書の優先権を主張する。前記明細書は2018年7月6日付けで出願された米国仮出願第62/694,510号明細書の優先権を主張する。これらの内容は全体的に本明細書中に援用される。
P毛管 = P源 - pgh
であってよい。
Claims (18)
- カートリッジであって、
当該カートリッジ本体が、キャップレス試料ウェルポートを画定しており、前記キャップレス試料ウェルポートが、試料物質と、前記キャップレス試料ウェルポートと流体連通した流体チャネルとを受容するように形成されており、前記流体チャネルが、第1軸線に沿って延びる第1流体チャネル部分と、第2軸線に沿って延びる第2流体チャネル部分とを含み、前記第1軸線が前記第2軸線に対して所定の角度を成しており、前記流体チャネルがさらにオーバーフロー流体チャネル部分を含む、カートリッジ本体と、
前記流体チャネルが前記キャップレス試料ウェルポートと当該流体リザーバとの間に延びており、前記流体チャネル内部に圧力が加えられると、前記試料物質を前記流体リザーバへ向かって導くように前記流体チャネルが形成され、前記オーバーフロー流体チャネル部分が前記流体チャネルに沿って、前記キャップレス試料ウェルポートと前記流体リザーバのリザーバポートとの間に配置されている、流体リザーバと、
を含む、カートリッジ。 - さらに、前記流体チャネルと流体連通する流体駆動ポートを含み、前記流体駆動ポートが、前記試料物質を前記流体リザーバへ向かって導くために前記流体チャネル内部に正圧が加えられるべく圧力源に動作的に接続されるように形成されている、請求項1に記載のカートリッジ。
- 前記第1及び第2流体チャネル部分が、3mm以下のチャネル深さ及び3mm以下のチャネル幅を画定している、請求項1に記載のカートリッジ。
- 前記オーバーフロー流体チャネル部分が、1.5mm以下のチャネル深さと、3mm以下のチャネル幅とを画定している、請求項1に記載のカートリッジ。
- 前記第1及び第2流体チャネル部分が、前記キャップレス試料ウェルポートから4mm以下の第1半径の周りに概ね延びており、そして前記オーバーフロー流体チャネル部分が、前記キャップレス試料ウェルポートから8mm以下の第2半径の周りに概ね延びている、請求項1に記載のカートリッジ。
- 前記流体チャネルがさらに第3流体チャネル部分を含み、前記第1流体チャネル部分が前記第3流体チャネル部分に対して平行であり、そして前記第2流体チャネル部分が前記第1及び第3流体チャネル部分に対して垂直である、請求項1に記載のカートリッジ。
- さらに、前記キャップレス試料ウェルポートと前記流体チャネルとの間に位置決めされたフィルタを含む、請求項1に記載のカートリッジ。
- 前記第1流体チャネル部分が第1長さを画定し、そして前記第2流体チャネル部分が第2長さを画定しており、前記第1及び第2長さがそれぞれ10mm以下である、請求項1に記載のカートリッジ。
- 前記流体チャネル内部に加えられる圧力が、前記流体リザーバからの負圧である、請求項1に記載のカートリッジ。
- カートリッジであって、
当該カートリッジ本体が、キャップレス試料ウェルポートを画定しており、前記キャップレス試料ウェルポートが、試料物質と、前記キャップレス試料ウェルポートと流体連通した流体チャネルとを受容するように形成されており、前記流体チャネルが試料流体チャネル部分及びオーバーフロー流体チャネル部分を含み、前記試料流体チャネル部分内部の試料物質に対する重力効果が前記流体チャネルの毛管作用を克服しないように、前記流体チャネルが形成されている、カートリッジ本体と、
前記流体チャネルが前記キャップレス試料ウェルポートと当該流体リザーバとの間に延びており、前記流体チャネル内部に圧力が加えられると、前記試料物質を前記流体リザーバへ向かって導くように前記流体チャネルが形成され、前記オーバーフロー流体チャネル部分が前記流体チャネルに沿って、前記キャップレス試料ウェルポートと前記流体リザーバのリザーバポートとの間に配置されている、流体リザーバと、
を含む、カートリッジ。 - 前記試料流体チャネル部分内部の試料物質に対する重力効果が前記流体チャネルの毛管作用を克服しないように、
前記試料流体チャネル部分が少なくとも1つの曲げ部を画定している、請求項10に記載のカートリッジ。 - 前記流体チャネルのチャネル幅及びチャネル深さが前記流体チャネルの毛管作用を定義する、請求項10に記載のカートリッジ。
- さらに、前記流体チャネルと流体連通する流体駆動ポートを含み、前記流体駆動ポートが、前記試料物質を前記流体リザーバへ向かって導くために前記流体チャネル内部に正圧が加えられるべく圧力源に動作的に接続されるように形成されている、請求項10に記載のカートリッジ。
- 前記試料流体チャネル部分が、3mm以下のチャネル深さ及び3mm以下のチャネル幅を画定している、請求項10に記載のカートリッジ。
- 前記オーバーフロー流体チャネル部分が、1.5mm以下のチャネル深さと、3mm以下のチャネル幅とを画定している、請求項10に記載のカートリッジ。
- 前記試料流体チャネル部分が、前記キャップレス試料ウェルポートから4mm以下の第1半径の周りに概ね延びており、そして前記オーバーフロー流体チャネル部分が、前記キャップレス試料ウェルポートから8mm以下の第2半径の周りに概ね延びている、請求項10に記載のカートリッジ。
- さらに、前記キャップレス試料ウェルポートと前記流体チャネルとの間に位置決めされたフィルタを含む、請求項10に記載のカートリッジ。
- 前記流体チャネル内部に加えられる圧力が、前記流体リザーバからの負圧である、請求項10に記載のカートリッジ。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862694510P | 2018-07-06 | 2018-07-06 | |
US62/694,510 | 2018-07-06 | ||
US16/146,121 | 2018-09-28 | ||
US16/146,121 US10974240B2 (en) | 2018-07-06 | 2018-09-28 | Fluidic channel for a cartridge |
PCT/US2019/038980 WO2020009838A1 (en) | 2018-07-06 | 2019-06-25 | Fluidic channel for a cartridge |
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Publication Number | Publication Date |
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JP2021529319A JP2021529319A (ja) | 2021-10-28 |
JP7384538B2 true JP7384538B2 (ja) | 2023-11-21 |
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JP2021500146A Active JP7384538B2 (ja) | 2018-07-06 | 2019-06-25 | カートリッジのための流体チャネル |
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US (1) | US10974240B2 (ja) |
EP (1) | EP3818368A4 (ja) |
JP (1) | JP7384538B2 (ja) |
CN (1) | CN112368573A (ja) |
WO (1) | WO2020009838A1 (ja) |
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US5230866A (en) * | 1991-03-01 | 1993-07-27 | Biotrack, Inc. | Capillary stop-flow junction having improved stability against accidental fluid flow |
EP1125129A1 (en) * | 1998-10-13 | 2001-08-22 | Biomicro Systems, Inc. | Fluid circuit components based upon passive fluid dynamics |
CA2374423C (en) * | 1999-05-28 | 2013-04-09 | Cepheid | Apparatus and method for analyzing a liquid sample |
US20050150766A1 (en) * | 2001-11-02 | 2005-07-14 | Andreas Manz | Capillary electrophoresis microchip system and method |
US7459127B2 (en) * | 2002-02-26 | 2008-12-02 | Siemens Healthcare Diagnostics Inc. | Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces |
DE10325110B3 (de) * | 2003-05-30 | 2005-01-13 | Universität Freiburg | Blasenfrei befüllbarer Fluidkanal und Verfahren zum Füllen eines Fluidkanals |
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-
2018
- 2018-09-28 US US16/146,121 patent/US10974240B2/en active Active
-
2019
- 2019-06-25 JP JP2021500146A patent/JP7384538B2/ja active Active
- 2019-06-25 EP EP19830154.1A patent/EP3818368A4/en active Pending
- 2019-06-25 WO PCT/US2019/038980 patent/WO2020009838A1/en unknown
- 2019-06-25 CN CN201980045478.7A patent/CN112368573A/zh active Pending
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US10974240B2 (en) | 2021-04-13 |
JP2021529319A (ja) | 2021-10-28 |
WO2020009838A1 (en) | 2020-01-09 |
EP3818368A1 (en) | 2021-05-12 |
CN112368573A (zh) | 2021-02-12 |
US20200009554A1 (en) | 2020-01-09 |
EP3818368A4 (en) | 2022-04-06 |
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