JP7382766B2 - Foaming solid bath additive - Google Patents

Description

The present invention relates to foamable solid bath preparations.

Foaming bath additives containing carbonates and organic acids are known to generate carbon dioxide bubbles in the bath water, allowing you to enjoy the foaming sensation, as well as providing a warming feeling and blood circulation promoting effect due to the carbon dioxide gas. ing. Research has also been conducted to create additional or synergistic effects by incorporating various ingredients into these bath preparations. For example, menthol is added to bath preparations in order to provide a cooling sensation when taking a bath.
Patent Document 1 describes a bath agent containing a metal inorganic salt and a superabsorbent polymer as main components, and one or more disinfectants selected from salicylic acid, methyl salicylate, dipotassium glycyrrhizylate, paraben, etc.; A foot bath additive is disclosed that contains an organic acid and an alkali as a carbon dioxide gas generating agent, and l-menthol, dl-camphor, etc. as highly volatile ingredients.

Japanese Patent Application Publication No. 11-189525

In foaming bath additives containing carbonates and organic acids, if an organic acid with high solubility in water is used, such as an organic acid with a solubility of 5 g or more in 100 mL of water at 20°C, the bath additive will not dissolve in the bath water. It has the advantage that it foams quickly because it melts quickly, so it warms up quickly during bathing, and the foaming strength is achieved when the bath additive starts to melt. However, there is a problem in that bubbling of carbon dioxide gas scatters organic acids that irritate the mucous membranes, which can be inhaled, resulting in ``choking'' (choking during bathing).
Patent Document 1 discloses a bath agent containing l-menthol and a carbon dioxide gas generating agent, but the amount of carbon dioxide gas generating agent blended is small and good foaming properties cannot be obtained. Therefore, if the amount of carbon dioxide gas generator is increased in order to maintain foaming properties, the irritating aroma caused by l-menthol will become stronger. Furthermore, if an organic acid with high solubility in water is added to a bath agent containing l-menthol, the choking caused by both the organic acid and l-menthol will be stronger. There is also a problem in that ``choking'' (choking when opening) occurs due to l-menthol when opening the packaging material of pharmaceutical products.
The present invention provides a foaming solid bath agent using an organic acid with high solubility in water as a foaming component and further containing l-menthol or its derivative, and a foaming solid bath agent containing the foaming solid bath agent in a packaging material. The objective of the present invention is to suppress choking when opening the package and when taking a bath in a solid bath preparation product.

The present inventor has proposed a foaming solid bath agent containing an organic acid with high solubility in water, a carbonate, and l-menthol or a derivative thereof (hereinafter also referred to as l-menthol etc.), which further contains methyl salicylate and It has been found that the above problems can be solved by containing a predetermined water-soluble polymer within a predetermined range.
That is, the present invention relates to the following [1] and [2].
[1] The following components (A), (B), (C), (D), and (E):
(A) An organic acid containing an organic acid (A1) having a solubility of 5 g or more in 100 mL of water at 20°C (B) Carbonate (C) l-menthol or its derivative (D) Methyl salicylate (E) At 25°C Contains a solid water-soluble polymer,
The mass ratio of the sum of component (A) and component (C) to component (D) [{(A)+(C)}/(D)] is 50 or more and 1000 or less, and the component (C) to component (E) is ) A foaming solid bath agent having a mass ratio [(C)/(E)] of 0.01 or more and 10 or less.
[2] A foaming solid bathing agent product in which the foaming solid bathing agent of [1] above is encapsulated in a packaging material.

According to the present invention, there is provided a foaming solid bath agent that provides a cooling sensation due to l-menthol, etc., foams quickly in bath water, and suppresses choking when opening a packaging material and when taking a bath; It is possible to provide a foamable solid bath agent product in which a solid bath agent is encapsulated in a packaging material.

[Foaming solid bath agent/Foaming solid bath agent product]
The foamable solid bath agent of the present invention (hereinafter also simply referred to as "solid bath agent") has the following components (A), (B), (C), (D), and (E):
(A) An organic acid containing an organic acid (A1) having a solubility of 5 g or more in 100 mL of water at 20°C (B) Carbonate (C) l-menthol or its derivative (D) Methyl salicylate (E) At 25°C Contains a solid water-soluble polymer,
The mass ratio of the sum of component (A) and component (C) to component (D) [{(A)+(C)}/(D)] is 50 or more and 1000 or less, and the component (C) to component (E) is ) has a mass ratio [(C)/(E)] of 0.01 or more and 10 or less.
The foamable solid bath agent product of the present invention (hereinafter also simply referred to as "solid bath agent product") is obtained by encapsulating the foamable solid bath agent in a packaging material.

The foaming solid bath agent of the present invention has the above-mentioned structure, so that the component (A) is an organic acid containing an organic acid (A1) having high solubility in water, and the component (C) is l-menthol or A foaming solid bath preparation containing the derivative also suppresses choking when opening the packaging material and when taking a bath. Although the reason is not necessarily clear, it is thought to be as follows.
It is thought that choking during bathing due to foaming solid bath additives is mainly caused by components (A) and (C). That is, as a foaming component, the organic acid (A1) that is highly soluble in water contained in component (A) and component (B) rapidly dissolve and foam in the bath water due to the action of component (C). It is thought that this, combined with the irritating scent, makes it easier to choke when taking a bath. However, by setting the mass ratio of the sum of component (A) and component (C) to component (D) [{(A)+(C)}/(D)] within the above range, the fragrance of component (D) It is thought that this product is able to promote the cooling sensation of l-menthol and the like, while suppressing volatilization of l-menthol and the like due to its excellent compatibility with l-menthol and the like, thereby suppressing choking during bathing.
Furthermore, choking caused by foaming solid bath additives when opening the packaging material is thought to be mainly caused by the irritating scent of component (C), but the mass ratio of component (C) to component (E) [ (C)/(E)] within the above range, component (C) was stably supported on component (E), and it is believed that this made it possible to suppress choking when the packaging material was opened.

Each component contained in the foamable solid bath agent of the present invention will be explained below.
<Component (A): Organic acid containing organic acid (A1)>
The solid bath agent of the present invention contains, as component (A), an organic acid (A1) having a solubility in 100 mL of water at 20°C of 5 g or more (hereinafter simply referred to as "organic acid (A1)" or "component (A1)"). Contains organic acids including By containing the component (A), the solid bath agent of the present invention can generate carbon dioxide gas through the action with the component (B) described below, thereby providing a blood circulation promoting effect and a good warming speed. . Furthermore, since the component (A) contains the organic acid (A1), it is quickly dissolved in the bath water, and carbon dioxide gas is rapidly generated. In this specification, "organic acid with high solubility in water" means an organic acid with solubility in 100 mL of water at 20° C. of 5 g or more. Moreover, foamability means that the bath agent quickly dissolves and foams in bath water.

Examples of organic acids (A1) include succinic acid (5.8), tartaric acid (21), L-tartaric acid (139), which is an isomer of tartaric acid, malic acid (56), citric acid (73), and maleic acid (78). ), glutaric acid (43), DL-2-pyrrolidone-5-carboxylic acid (5.67), etc., and these can be contained alone or in combination of two or more. Among them, from the viewpoint of imparting good warming speed and foaming properties, one or more selected from the group consisting of succinic acid, tartaric acid, L-tartaric acid, and malic acid is preferable, and from the viewpoint of improving storage stability, It is more preferable to contain succinic acid. The numerical value in parentheses after each organic acid is its solubility in 100 mL of water at 20° C. (unit: g/100 mL-H ₂ O).

The content of the organic acid (A1) in the component (A) contained in the solid bath agent of the present invention is preferably 30% by mass or more, more preferably 50% by mass or more, from the viewpoint of imparting foaming properties. The content is preferably 75% by mass or more, even more preferably 95% by mass or more, and preferably substantially 100% by mass or less.
Component (A) in the solid bath agent of the present invention may have an organic acid (A1) content of 100% by mass, that is, it may consist only of the organic acid (A1).

Component (A) in the solid bath agent of the present invention may contain an organic acid (A2) other than the organic acid (A1) (hereinafter also simply referred to as "organic acid (A2)"). The organic acid (A2) is an organic acid having a solubility in 100 mL of water at 20° C. of less than 5 g. Examples of such organic acids (A2) include fumaric acid (0.6), adipic acid (1.5), benzoic acid (0.3), phthalic acid (0.7), and salicylic acid (0.2). These may be contained alone or in combination of two or more. Among these, fumaric acid is preferred from the viewpoint of storage stability and prevention of choking during bathing. The numerical value in parentheses after each organic acid is its solubility in 100 mL of water at 20° C. (unit: g/100 mL-H ₂ O).
When the solid bath agent of the present invention contains an organic acid (A2), the content of the organic acid (A2) in the component (A) is preferably 70% by mass from the viewpoint of ensuring foaming speed in bath water. The content is preferably at most 50% by mass, still more preferably at most 25% by mass, even more preferably at most 5% by mass.

The content of component (A) in the solid bath agent of the present invention is preferably 5% by mass or more, more preferably 20% by mass or more, and even more preferably is 30% by mass or more, even more preferably 40% by mass or more, even more preferably 45% by mass or more. Further, the content of component (A) in the solid bath agent of the present invention is preferably 70% by mass or less, and more Preferably it is 65% by mass or less, more preferably 55% by mass or less.

<Component (B): carbonate>
The solid bath agent of the present invention contains a carbonate as component (B). Component (B) generates carbon dioxide gas by interacting with component (A) when the solid bath agent of the present invention is added to bath water, thereby promoting a blood circulation effect and imparting a good warming speed. I can do it.
Component (B) includes alkali metal carbonates such as sodium carbonate and potassium carbonate; alkaline earth metal carbonates such as calcium carbonate and magnesium carbonate; and alkali metal bicarbonates such as sodium hydrogen carbonate and potassium hydrogen carbonate; These may be contained alone or in combination of two or more. Among these, from the viewpoint of imparting good moldability, heating speed, and foamability, one or more selected from the group consisting of sodium carbonate, sodium hydrogen carbonate, and calcium carbonate is preferred, and sodium carbonate and sodium hydrogen carbonate are preferred. One or two selected from the group is more preferred.
Component (B) preferably contains an alkali metal carbonate from the perspective of imparting good moldability, and preferably contains an alkali metal bicarbonate from the perspective of imparting warming speed and good foamability. . That is, component (B) preferably contains an alkali metal carbonate and an alkali metal bicarbonate, and more preferably contains sodium carbonate and sodium hydrogen carbonate.

When using an alkali metal carbonate and an alkali metal bicarbonate together as component (B), the ratio is not particularly limited, but from the viewpoint of imparting good moldability, heating speed, and foamability, The mass ratio of metal bicarbonate [alkali metal bicarbonate/alkali metal carbonate] is preferably 0.2 or more, more preferably 0.3 or more, still more preferably 0.5 or more, and preferably 4. It is 0 or less, more preferably 2.0 or less, even more preferably 1.5 or less.

The content of component (B) in the solid bath agent of the present invention is preferably 10% by mass or more, more preferably 15% by mass or more, still more preferably 20% by mass or more, from the viewpoint of imparting good warming speed and foaming properties. % by mass or more, even more preferably 25% by mass or more, even more preferably 30% by mass or more, and preferably 65% by mass or less, more preferably 60% by mass or less, still more preferably 55% by mass or less, More preferably, it is 50% by mass or less.

The mass ratio [(B)/(A1)] of component (B) to component (A1) in the solid bath agent of the present invention is preferably 0.5 or more, more preferably 0.5 or more, from the viewpoint of suppressing choking during bathing. is 0.6 or more, more preferably 0.8 or more. In addition, from the viewpoint of imparting foamability, the mass ratio [(B)/(A1)] is preferably 4 or less, more preferably 2 or less, even more preferably 1.0 or less, and even more preferably 0.9. It is as follows.

<Component (C): l-menthol or its derivative>
The solid bath agent of the present invention contains l-menthol or a derivative thereof as component (C). By containing such component (C), a good cooling sensation can be imparted. Examples of l-menthol derivatives include menthyl lactate, menthyl acetate, and menthone. Component (C), l-menthol or its derivatives, may contain one or more types, and l-menthol is particularly preferred.
The content of component (C) in the solid bath agent of the present invention is preferably 0.04% by mass or more, more preferably 0.1% by mass, from the viewpoint of providing a good cooling sensation and sustaining this feeling. % or more, more preferably 0.2% by mass or more. In addition, the content of component (C) is preferably 1.5% by mass or less, more preferably 1.0% by mass or less, and Preferably it is 0.8% by mass or less, and even more preferably 0.6% by mass or less.

<Component (D): Methyl salicylate>
The solid bath agent of the present invention contains methyl salicylate as component (D). By containing such component (D), choking caused by component (A) and component (C) during bathing can be suppressed due to the above-described mechanism of action. In addition, it is possible to impart a refreshing feeling due to the unique aroma derived from component (D), and it can also be expected that the effect of recovering from fatigue after exercise such as sports can be obtained.
The content of component (D) in the solid bath preparation of the present invention is preferably 0.01% by mass or more, more preferably 0.01% by mass or more, from the viewpoint of suppressing choking during bathing and providing a good refreshing feeling. is 0.05% by mass or more, more preferably 0.10% by mass or more, even more preferably 0.12% by mass or more. Further, the content of component (D) is preferably 1% by mass or less, more preferably 0.8% by mass or less, from the viewpoint of ensuring the effects derived from components (A) to (C). More preferably, it is 0.5% by mass or less, and even more preferably 0.3% by mass or less.

In the solid bath agent of the present invention, the mass ratio of the sum of component (A) and component (C) to component (D) [{(A)+(C)}/(D)] is such that foaming occurs rapidly in bath water. From the viewpoint of providing a good cooling sensation derived from component (C), it is 50 or more, preferably 65 or more, more preferably 100 or more, and still more preferably 250 or more. In addition, the mass ratio [{(A)+(C)}/(D)] is 1000 or less, preferably 930 or less, and more preferably 450 or less, from the viewpoint of suppressing choking during bathing. Yes, and more preferably 350 or less.

In the solid bath agent of the present invention, the mass ratio of component (C) to component (D) [(C)/(D)] is preferably 0.05 or more from the viewpoint of suppressing choking during bathing, It is more preferably 0.1 or more, still more preferably 0.5 or more, and even more preferably 1.2 or more. In addition, the mass ratio [(C)/(D)] is preferably 12 or less, more preferably 10 or less, from the viewpoint of suppressing choking during bathing and providing a good refreshing feeling. , more preferably 8 or less, even more preferably 6 or less.

<Component (E): Water-soluble polymer that is solid at 25°C>
The solid bath preparation of the present invention contains a water-soluble polymer that is solid at 25° C. as component (E) from the viewpoint of suppressing choking when the packaging material is opened. In the present invention, a water-soluble polymer refers to a polymer compound that dissolves at least 0.5% by mass in 100 g of pure water at 25°C, and being solid at 25°C means that the softening point or melting point is It has the same meaning as indicating a temperature of 30°C or higher.

Examples of the water-soluble polymers include synthetic water-soluble polymers such as polyethylene glycol, polyvinylpyrrolidone, polyethyleneimine, and polyvinyl alcohol; glue, gelatin, collagen protein, casein, sodium alginate, carrageenan, furcellan, tamarind gum, pectin, Natural water-soluble polymers such as gum arabic, guar gum, xanthan gum, tragacanth gum, locust bean gum, dextrin, dextran, agar, starch; carboxymethyl cellulose, methyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, cellulose acetate phthalate, alginate propylene glycol ester, Semi-synthetic water-soluble polymers such as oxidized starch, esterified starch, etherified starch, cationic starch, etc., which are solid at 25°C, may contain one or more of these. . Among these, from the viewpoint of suppressing choking when opening the packaging material and imparting excellent storage stability, one or two selected from the group consisting of polyethylene glycol and dextrin are preferred, and polyethylene glycol is more preferred. The molecular weight of polyethylene glycol is preferably 4,000 or more and 10,000 or less, more preferably 5,000 or more and 9,000 or less.

The content of component (E) in the solid bath agent of the present invention is preferably 0.01% by mass or more, more preferably 0.05% by mass or more, and even more preferably is 0.3% by mass or more. In addition, the content of component (E) is preferably 15% by mass or less, more preferably 9% by mass or less, and even more preferably is 3% by mass or less.

In the solid bath agent of the present invention, the mass ratio [(C)/(E)] of component (C) to component (E) is 0.01 from the viewpoint of providing a good cooling sensation derived from component (C). or more, preferably 0.05 or more, more preferably 0.1 or more, still more preferably 0.3 or more, even more preferably 0.4 or more. In addition, from the viewpoint of suppressing choking when opening the packaging material, it is 10 or less, preferably 5 or less, more preferably 4 or less, even more preferably 3 or less, and even more preferably 1.2 or less. .

The solid bath additive of the present invention may appropriately contain other components that are commonly used in bath additives. Such components include, for example, nonionic surfactants such as sucrose fatty acid ester, polyethylene glycol fatty acid ester, polyoxyethylene alkyl ether, polyoxyethylene hydrogenated castor oil, and other surfactants; sodium sulfate, magnesium sulfate, and chloride. Inorganic salts other than the above ingredients such as potassium, sodium chloride, potassium nitrate, sodium nitrate, sodium polyphosphate, ammonium chloride, iron sulfate, sodium phosphate, sodium thiosulfate; Excipients such as calcium silicate and glucose; Disintegration aids agents; medicinal ingredients such as crude drugs; pigments; fragrances (excluding the above-mentioned components (C) and (D)); oils; and the like.

The fragrance (excluding the above-mentioned components (C) and (D)) is not particularly limited as long as it can be used in bath preparations, and can contain various fragrance components.
Such fragrances include, for example, the fragrances described in "Synthetic Fragrances Chemistry and Product Knowledge" (written by Genichi Indo, published by Kagaku Kogyo Nippo, revised and revised edition in 2005), such as myrcene, ocimene, camphene, terpinolene, and alpha-terpinene. , terpene-based hydrocarbon or sesquiterpene-based hydrocarbon fragrances such as phellandrene, alpha-phellandrene, paracymene, farnesene, cedrene, longifolene, copaene, guaien, pacholene, glujunene, limonene, citral, terpinene;
Examples include one or more types selected from alcohol-based fragrances, aldehyde-based fragrances, ketone-based fragrances, ether-based fragrances, oxide-based fragrances, ester-based fragrances, lactone-based fragrances, and the like.
Moreover, these fragrances can also be contained as various mixed fragrances depending on the desired fragrance.

(Dosage form)
The preferred dosage form (product form) for use of the solid bath preparation of the present invention is a tablet. Tablets include compressed tablets and briquette-type preparations, and compressed tablets are more preferable from the viewpoint of sustained foaming.
When the solid bath preparation of the present invention is in the form of tablets or briquettes, it can be manufactured by conventional methods such as compression molding using a tablet press or briquette machine.
In the production of compressed tablets or briquettes, for example, a powder obtained by dry blending all the components constituting the solid bath preparation of the present invention may be subjected to compression molding, or some of the components may be granulated in advance. Alternatively, after molding, the resulting mixture may be mixed with the remaining components and subjected to compression molding.

(Foaming solid bath agent products)
The foamable solid bath agent product of the present invention is made by encapsulating the solid bath agent of the present invention in a packaging material, and can suppress choking when the packaging material of the product is opened.
The shape of the packaging material is not particularly limited as long as it has a structure that can enclose the solid bath agent of the present invention, and examples thereof include a bag shape, a bottle shape, a tray shape, a cup shape, and the like. Among these, bag-shaped packaging materials are preferred.
The material constituting the packaging material is not particularly limited as long as it can enclose the solid bath agent of the present invention. For example, in the case of a bag-like packaging material, a resin film or a laminated film in which an inorganic thin film made of metal or metal oxide is laminated on a resin film can be used.

EXAMPLES Hereinafter, the present invention will be explained with reference to examples, but the present invention is not limited to the scope of the examples.

Examples 1 to 14, Comparative Examples 1 to 2 (manufacture and evaluation of solid bath additives)
Using a powder obtained by mixing the ingredients shown in Table 1, a rotary tablet machine was used to make tablets with a mass of 69 to 71 g and a tablet height of 19.3 to 19.5 mm at a compression speed of 20 tablets/ The mixture was compressed into tablets to produce tablet-shaped solid bath preparations. In addition, choking upon opening the package and choking upon bathing were evaluated using the following method. The results are shown in Table 1. Note that all the contents listed in Table 1 are active ingredient amounts (% by mass).

<Evaluation of choking upon opening>
A solid bath agent product was prepared by enclosing 70 g (1 tablet) of the solid bath agent of each example in an aluminum pillow (manufactured by Dainippon Printing Co., Ltd., 9 cm x 11 cm) and left at room temperature for 24 hours. After opening the packaging material, one expert panelist brought his/her face close to the opening and evaluated the "choking" that occurred when opening the packaging material according to the following criteria.
A: I feel a mild scent, and I don't choke at all B: I feel a mild scent, and I temporarily feel slightly choked C: I feel a slight irritation from the scent, and I choke a little D: I feel a strong irritation from the scent, and very suffocating

<Assessment of choking during bathing>
Pour 150L of 40°C bath water into a bathtub, have one expert panelist take a bath up to his shoulders, and add 70g (1 tablet) of each solid bath preparation until the solid bath preparation is completely dissolved. The ``suffocation'' that occurs in patients was evaluated according to the following criteria.
A: I feel a mild scent, and I don't choke at all B: I feel a mild scent, and I temporarily feel slightly choked C: I feel a slight irritation from the scent, and I choke a little D: I feel a strong irritation from the scent, and very suffocating

<Evaluation of foamability>
Pour 150 L of 40°C bath water into a bathtub, add 70 g (1 tablet) of each solid bath agent, and immediately have one expert panelist take a bath. Evaluation was made according to the following criteria.
A: Very strong foaming B: Slightly strong foaming C: Weak foaming

In Table 1, *1 to *6 are as follows.
*1: L-menthol, "Menthol JP COS" manufactured by Takasago International Corporation, 100% active ingredient
*2: Methyl Salicylate, manufactured by Inoue Fragrance Manufacturing Co., Ltd., 100% active ingredient
*3: Polyethylene glycol, “K-PEG6000 LA” manufactured by Kao Corporation, molecular weight 6,000
*4: Dextrin, “Dextrin CZRM-X” manufactured by Nippon Star Chemical Co., Ltd.
*5: Fragrance ingredients, fragrance ingredients other than the above-mentioned component (C) and component (D) (compounded perfume)
*6: Glucose, “Anhydrous Crystalline Glucose” manufactured by Nihon Shokuhin Kako Co., Ltd.

Table 1 shows that the solid bath preparation of the present invention can suppress choking during bathing and choking when opening the solid bath preparation product sealed in the packaging material.

According to the present invention, there is provided a foaming solid bath agent that provides a cooling sensation due to l-menthol, etc., foams quickly in bath water, and suppresses choking when opening a packaging material and when taking a bath; It is possible to provide a foamable solid bath agent product in which a solid bath agent is encapsulated in a packaging material.

Claims (6)

The following components (A), (B), (C), (D), and (E):
(A) Organic acid containing organic acid (A1) having a solubility in 100 mL of water at 20°C of 5 g or more , 10% by mass or more and 70% by mass or less
(B) Carbonate (C) One or more selected from the group consisting of l-menthol, menthyl lactate, menthyl acetate, and menthone 0.1% by mass or more and 1.5% by mass or less
(D) Methyl salicylate 0.05% by mass or more and 0.5% by mass or less
(E) Water-soluble polymer that is solid at 25°C 0.1% by mass or more and 3% by mass or less
Contains
The mass ratio of the sum of component (A) and component (C) to component (D) [{(A)+(C)}/(D)] is 50 or more and 1000 or less, and the component (C) to component (E) is ) A foaming solid bath agent having a mass ratio [(C)/(E)] of 0.01 or more and 10 or less. The foamable solid bath agent according to claim 1, wherein the content of the organic acid (A1) in the component (A) is 30% by mass or more. The foaming solid bath agent according to claim 1 or 2, wherein the organic acid (A1) is one or more selected from the group consisting of succinic acid, tartaric acid, and malic acid. The foamable solid bath agent according to any one of claims 1 to 3, wherein the component (E) is one or two selected from the group consisting of polyethylene glycol and dextrin. The foamable solid bath according to any one of claims 1 to 4, wherein the mass ratio [(C)/(D)] of the component (C) to the component (D) is 0.05 or more and 12 or less. agent. A foamable solid bath agent product comprising the foamable solid bath agent according to any one of claims 1 to 5 encapsulated in a packaging material.