JP7330983B2 - 歯周炎の診断方法、使用及びキット - Google Patents

歯周炎の診断方法、使用及びキット Download PDF

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JP7330983B2
JP7330983B2 JP2020538662A JP2020538662A JP7330983B2 JP 7330983 B2 JP7330983 B2 JP 7330983B2 JP 2020538662 A JP2020538662 A JP 2020538662A JP 2020538662 A JP2020538662 A JP 2020538662A JP 7330983 B2 JP7330983 B2 JP 7330983B2
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periodontitis
protein
light chain
concentration
free light
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JP2021510815A (ja
JP2021510815A5 (enExample
Inventor
ヘルベン コーイマン
アミル フセイン ルメール
カール フラッセ
ヤヘル マリヌス カレル ヨハネス デ
イアン レスリー キャンベル チャップル
メリッサ マッケイ フラント
フィリップ プレショウ
ジョン ジェイ テイラー
ハーツカンプ ミヒャエル アレックス ファン
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Koninklijke Philips NV
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Koninklijke Philips NV
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/6857Antibody fragments
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/18Dental and oral disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
JP2020538662A 2018-01-16 2019-01-09 歯周炎の診断方法、使用及びキット Active JP7330983B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023110445A JP2023134563A (ja) 2018-01-16 2023-07-05 歯周炎の診断方法、使用及びキット

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18151839.0 2018-01-16
EP18151839.0A EP3511716A1 (en) 2018-01-16 2018-01-16 Periodontitis diagnostic methods, uses and kits
PCT/EP2019/050364 WO2019141547A1 (en) 2018-01-16 2019-01-09 Periodontitis diagnostic methods, uses and kits

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JP2021510815A5 JP2021510815A5 (enExample) 2022-01-04
JP7330983B2 true JP7330983B2 (ja) 2023-08-22

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JP2023110445A Pending JP2023134563A (ja) 2018-01-16 2023-07-05 歯周炎の診断方法、使用及びキット

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US (1) US20210063412A1 (enExample)
EP (2) EP3511716A1 (enExample)
JP (2) JP7330983B2 (enExample)
CN (1) CN111630389B (enExample)
CA (1) CA3088339A1 (enExample)
RU (1) RU2020127365A (enExample)
WO (1) WO2019141547A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3553520A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Methods, uses and kits for monitoring or predicting response to periodontal disease treatment
EP3553523A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Diagnostics of mild or advanced periodontitis
WO2022096893A1 (en) 2020-11-04 2022-05-12 The University Of Birmingham Device

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009055820A2 (en) 2007-10-26 2009-04-30 The Regents Of The University Of California Salivary protein biomarkers for human oral cancer
JP2013117382A (ja) 2011-12-01 2013-06-13 Kao Corp 歯周病マーカー
JP2015529333A (ja) 2012-09-10 2015-10-05 コーニンクレッカ フィリップス エヌ ヴェ Ft−icr−ms/msを使用した、歯肉炎および歯周炎のバイオマーカーのための唾液プロテオームの分析

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179606B2 (en) * 2001-11-23 2007-02-20 Syn X Pharma, Inc. IG heavy chain, IG kappa, IG lambda biopolymer markers predictive of Alzheimer's disease
CN101523218B (zh) * 2006-09-29 2014-07-09 霍夫曼-拉罗奇有限公司 评估类风湿性关节炎患者疾病进展的风险
EP2430451B1 (en) * 2009-05-14 2014-08-13 The Chancellors, Masters and Scholars of the University of Oxford Clinical diagnosis of hepatic fibrosis / cirrhosis using low abundant human plasma protein biomarkers
WO2010151789A1 (en) * 2009-06-25 2010-12-29 The Regents Of The University Of California Salivary transcriptomic and microbial biomarkers for pancreatic cancer
US20130116343A1 (en) * 2010-04-21 2013-05-09 Board Of Regents Of The University Of Texas System Salivary Protein Markers for Detection of Breast Cancer
JP5740523B1 (ja) * 2013-12-11 2015-06-24 株式会社 資生堂 腎不全の早期診断マーカー
EP3233897B1 (en) * 2014-12-19 2021-02-17 Universite de Nantes Anti il-34 antibodies
GB201708262D0 (en) * 2017-05-23 2017-07-05 Binding Site Group Ltd Assay for plasma cell associated disease

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009055820A2 (en) 2007-10-26 2009-04-30 The Regents Of The University Of California Salivary protein biomarkers for human oral cancer
JP2013117382A (ja) 2011-12-01 2013-06-13 Kao Corp 歯周病マーカー
JP2015529333A (ja) 2012-09-10 2015-10-05 コーニンクレッカ フィリップス エヌ ヴェ Ft−icr−ms/msを使用した、歯肉炎および歯周炎のバイオマーカーのための唾液プロテオームの分析

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
B.J. Haigh et al.,Alterations in the salivary proteome associated with periodontitis,Journal of Clinical Periodontology,2010年,Vol.37,pp.241-247
BELLEI Bertoldi C. et al.,Non-bacterial protein expression in periodontal pockets by proteome analysis,Journal of Clinical Periodontology,2013年,Article No.12050
H. Range et al.,Salivary proteome modifications associated with periodontitis in obese patients,Journal of Clinical Periodontology,2012年,Vol.39,pp.799-806
HEANEY Jennifer L. J. et al.,Salivary immunoglobulin free light chains: reference ranges and responses to exercise in young and older adults,Exercise Immunology Review,2016年,Vol.22,pp.28-41
RAUBENHEIMER Erich et al.,Salivary immunoglobulin related proteins in 24 patients with multiple myeloma,EUROPEAN JOURNAL OF CANCER. PART B, ORAL ONCOLOGY,1993年,Vol.29B, No.4,pp.295-297

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RU2020127365A3 (enExample) 2022-04-08
WO2019141547A1 (en) 2019-07-25
RU2020127365A (ru) 2022-02-17
CN111630389B (zh) 2025-04-22
EP3511716A1 (en) 2019-07-17
JP2023134563A (ja) 2023-09-27
JP2021510815A (ja) 2021-04-30
CN111630389A (zh) 2020-09-04
EP3740759A1 (en) 2020-11-25
US20210063412A1 (en) 2021-03-04
EP3740759B1 (en) 2025-04-30
EP3740759C0 (en) 2025-04-30
CA3088339A1 (en) 2019-07-25

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