JP7314139B2 - Lemd1を標的とするがんワクチンおよびその使用 - Google Patents

Lemd1を標的とするがんワクチンおよびその使用 Download PDF

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JP7314139B2
JP7314139B2 JP2020532714A JP2020532714A JP7314139B2 JP 7314139 B2 JP7314139 B2 JP 7314139B2 JP 2020532714 A JP2020532714 A JP 2020532714A JP 2020532714 A JP2020532714 A JP 2020532714A JP 7314139 B2 JP7314139 B2 JP 7314139B2
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seq
amino acid
nucleic acid
acid sequence
fragment
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JP2021506264A (ja
Inventor
イェン チエン
スレイガー アナ
ガーマン ブラッドリー
クーチ ニール
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イノビオ ファーマシューティカルズ,インコーポレイティド
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001184Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2020532714A 2017-12-13 2018-12-13 Lemd1を標的とするがんワクチンおよびその使用 Active JP7314139B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023084035A JP7633306B2 (ja) 2017-12-13 2023-05-22 Lemd1を標的とするがんワクチンおよびその使用
JP2025018136A JP2025065334A (ja) 2017-12-13 2025-02-06 Lemd1を標的とするがんワクチンおよびその使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762598329P 2017-12-13 2017-12-13
US62/598,329 2017-12-13
US201762598612P 2017-12-14 2017-12-14
US62/598,612 2017-12-14
PCT/US2018/065534 WO2019118771A1 (en) 2017-12-13 2018-12-13 Cancer vaccines targeting lemd1 and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023084035A Division JP7633306B2 (ja) 2017-12-13 2023-05-22 Lemd1を標的とするがんワクチンおよびその使用

Publications (2)

Publication Number Publication Date
JP2021506264A JP2021506264A (ja) 2021-02-22
JP7314139B2 true JP7314139B2 (ja) 2023-07-25

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020532714A Active JP7314139B2 (ja) 2017-12-13 2018-12-13 Lemd1を標的とするがんワクチンおよびその使用
JP2023084035A Active JP7633306B2 (ja) 2017-12-13 2023-05-22 Lemd1を標的とするがんワクチンおよびその使用
JP2025018136A Withdrawn JP2025065334A (ja) 2017-12-13 2025-02-06 Lemd1を標的とするがんワクチンおよびその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023084035A Active JP7633306B2 (ja) 2017-12-13 2023-05-22 Lemd1を標的とするがんワクチンおよびその使用
JP2025018136A Withdrawn JP2025065334A (ja) 2017-12-13 2025-02-06 Lemd1を標的とするがんワクチンおよびその使用

Country Status (11)

Country Link
US (2) US11338028B2 (https=)
EP (1) EP3724217A4 (https=)
JP (3) JP7314139B2 (https=)
KR (2) KR20240096711A (https=)
CN (1) CN111479822A (https=)
AU (2) AU2018384824B2 (https=)
BR (1) BR112020011620A2 (https=)
CA (1) CA3084137A1 (https=)
MX (2) MX2020006305A (https=)
RU (1) RU2760984C1 (https=)
WO (1) WO2019118771A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040229277A1 (en) 2001-09-18 2004-11-18 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
JP2005537007A (ja) 2002-08-30 2005-12-08 オンコセラピー・サイエンス株式会社 結腸癌および胃癌の診断方法
JP2013532972A (ja) 2010-06-25 2013-08-22 アダムド エスピー.ゼット オー.オー. 抗癌性融合タンパク質
JP2016501536A (ja) 2012-12-13 2016-01-21 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア Wt1ワクチン

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1954826A4 (en) 2005-11-27 2010-05-05 Compugen Ltd NEW NUCLEOTIDE AND AMINO ACID SEQUENCES AND TESTS AND METHOD FOR THEIR USE FOR DIAGNOSIS
DK2091965T3 (da) 2006-10-17 2013-08-05 Oncotherapy Science Inc Peptidvacciner mod cancere, der udtrykker MPHOSPH1- eller DEPDC1-polypeptider
KR101174452B1 (ko) * 2009-05-11 2012-08-16 한국생명공학연구원 대장암 및 전이에 대한 바이오마커, 이를 이용한 대장암 진단 및 치료제 스크리닝
JP2014525584A (ja) * 2011-08-31 2014-09-29 オンコサイト コーポレーション 癌の治療および診断のための方法および組成物
US20140315743A1 (en) * 2011-10-03 2014-10-23 Karen Chapman Methods and Compositions for the Treatment and Diagnosis of Ovarian Cancer
AU2013243948A1 (en) * 2012-04-02 2014-10-30 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins associated with human disease
WO2017203526A1 (en) * 2016-05-23 2017-11-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of diagnosing cancer using cancer testis antigens

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040229277A1 (en) 2001-09-18 2004-11-18 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
JP2005537007A (ja) 2002-08-30 2005-12-08 オンコセラピー・サイエンス株式会社 結腸癌および胃癌の診断方法
JP2013532972A (ja) 2010-06-25 2013-08-22 アダムド エスピー.ゼット オー.オー. 抗癌性融合タンパク質
JP2016501536A (ja) 2012-12-13 2016-01-21 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア Wt1ワクチン

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
UniProtKB, Accession No. B4DYE5,Last modified: 2008-09-23,[online], [retrieved on 2022.11.15], <URL: https://www.uniprot.org/uniprotkb/B4DYE5/entry>

Also Published As

Publication number Publication date
US11338028B2 (en) 2022-05-24
EP3724217A1 (en) 2020-10-21
KR20200096959A (ko) 2020-08-14
AU2018384824B2 (en) 2022-08-04
AU2018384824A8 (en) 2020-07-30
CN111479822A (zh) 2020-07-31
AU2022263546A1 (en) 2022-12-08
US20190175712A1 (en) 2019-06-13
JP2025065334A (ja) 2025-04-17
RU2760984C1 (ru) 2021-12-02
EP3724217A4 (en) 2022-01-12
CA3084137A1 (en) 2019-06-20
JP2023111915A (ja) 2023-08-10
US20220265800A1 (en) 2022-08-25
KR102673699B1 (ko) 2024-06-17
MX2024005404A (es) 2024-08-06
JP7633306B2 (ja) 2025-02-19
WO2019118771A1 (en) 2019-06-20
MX2020006305A (es) 2020-09-17
KR20240096711A (ko) 2024-06-26
BR112020011620A2 (pt) 2020-12-08
JP2021506264A (ja) 2021-02-22
AU2018384824A1 (en) 2020-07-16

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