JP7307047B2 - 組換えｖｗｆの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療 - Google Patents

組換えｖｗｆの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療 Download PDF

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JP7307047B2
JP7307047B2 JP2020500617A JP2020500617A JP7307047B2 JP 7307047 B2 JP7307047 B2 JP 7307047B2 JP 2020500617 A JP2020500617 A JP 2020500617A JP 2020500617 A JP2020500617 A JP 2020500617A JP 7307047 B2 JP7307047 B2 JP 7307047B2
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rvwf
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JP2020526525A (ja
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ミランダ チャップマン
ブルース イーウェンスタイン
ベッティーナ プロダー
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Takeda Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2020500617A 2017-07-07 2018-07-09 組換えｖｗｆの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療 Active JP7307047B2 (ja)

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JP2023106554A JP7641327B2 (ja) 2017-07-07 2023-06-29 組換えｖｗｆの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療

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US201762530027P 2017-07-07 2017-07-07
US62/530,027 2017-07-07
PCT/US2018/041320 WO2019010497A1 (en) 2017-07-07 2018-07-09 TREATMENT OF GASTROINTESTINAL BLEEDING IN PATIENTS WITH A SEVERE FORM OF VON WILLEBRAND'S DISEASE BY RECOMBINANT VWF ADMINISTRATION

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JP2020526525A5 JP2020526525A5 (enExample) 2021-08-12
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JP2023106554A Active JP7641327B2 (ja) 2017-07-07 2023-06-29 組換えｖｗｆの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療

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US (5) US10632176B2 (enExample)
EP (2) EP3648788B1 (enExample)
JP (2) JP7307047B2 (enExample)
KR (1) KR20200037235A (enExample)
CN (1) CN111436193A (enExample)
AU (2) AU2018298233B2 (enExample)
BR (1) BR112020000321A2 (enExample)
CA (1) CA3069295A1 (enExample)
CO (1) CO2020001322A2 (enExample)
DK (1) DK3648788T3 (enExample)
ES (1) ES2986574T3 (enExample)
FI (1) FI3648788T5 (enExample)
PL (1) PL3648788T3 (enExample)
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WO (1) WO2019010497A1 (enExample)

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BR112020000321A2 (pt) 2017-07-07 2020-07-14 Baxalta Incorporated método para tratamento de sangramento gastrointestinal em um sujeito com doença de von willebrand.
US20220395560A1 (en) * 2019-02-01 2022-12-15 Takeda Pharmaceutical Company Limited METHODS OF PROPHYLACTIC TREATMENT USING RECOMBINANT VWF (rVWF)
US12128090B2 (en) * 2019-02-01 2024-10-29 Takeda Pharmaceutical Company Limited Methods of prophylactic treatment using recombinant VWF (rVWF)
WO2021032646A1 (en) * 2019-08-16 2021-02-25 Octapharma Ag Stabilizing buffer for factor viii and vwf

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US8597910B1 (en) 1985-04-11 2013-12-03 Children's Medical Center Corporation DNA encoding Von Willebrand Factor (VWF) and methods and cells for producing VFW, and VFW produced by the DNA, methods and cells
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AT406373B (de) 1997-02-27 2000-04-25 Immuno Ag Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie
AT405485B (de) 1997-05-28 1999-08-25 Immuno Ag Eine das vwf-propeptid enthaltende pharmazeutische präparation
US6531577B1 (en) 1997-12-15 2003-03-11 Hemasure Denmark A/S von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations
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JP5784907B2 (ja) 2007-12-28 2015-09-24 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 組換え型ｖｗｆ製剤
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US20230122958A1 (en) 2023-04-20
AU2018298233B2 (en) 2025-04-24
US11529395B2 (en) 2022-12-20
BR112020000321A2 (pt) 2020-07-14
US20200206318A1 (en) 2020-07-02
US20210169989A1 (en) 2021-06-10
PT3648788T (pt) 2024-08-23
RU2020105682A3 (enExample) 2021-10-15
ES2986574T3 (es) 2024-11-12
AU2018298233A1 (en) 2020-01-30
JP2023123738A (ja) 2023-09-05
EP4424366A3 (en) 2024-12-04
JP2020526525A (ja) 2020-08-31
FI3648788T3 (fi) 2024-08-16
EP4424366A2 (en) 2024-09-04
FI3648788T5 (fi) 2024-09-09
JP7641327B2 (ja) 2025-03-06
PL3648788T3 (pl) 2024-10-07
EP3648788B1 (en) 2024-05-22
KR20200037235A (ko) 2020-04-08
AU2025205392A1 (en) 2025-09-25
RU2020105682A (ru) 2021-08-10
US10905746B2 (en) 2021-02-02
EP3648788A1 (en) 2020-05-13
US12016904B2 (en) 2024-06-25
US10632176B2 (en) 2020-04-28
CN111436193A (zh) 2020-07-21
CO2020001322A2 (es) 2020-02-18
US20240316160A1 (en) 2024-09-26
DK3648788T3 (da) 2024-08-19
CA3069295A1 (en) 2019-01-10
US20190091299A1 (en) 2019-03-28
WO2019010497A1 (en) 2019-01-10

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