JP7293209B2 - 医薬剤形 - Google Patents

医薬剤形 Download PDF

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Publication number
JP7293209B2
JP7293209B2 JP2020518798A JP2020518798A JP7293209B2 JP 7293209 B2 JP7293209 B2 JP 7293209B2 JP 2020518798 A JP2020518798 A JP 2020518798A JP 2020518798 A JP2020518798 A JP 2020518798A JP 7293209 B2 JP7293209 B2 JP 7293209B2
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Japan
Prior art keywords
active agent
matrix formulation
sustained release
core
weight
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Application number
JP2020518798A
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English (en)
Japanese (ja)
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JP2021500316A (ja
JP2021500316A5 (enExample
Inventor
アクジャ，オズギュル
ハリス，ステファン
マニオン，リチャード
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purdue Pharma LP
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Purdue Pharma LP
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Publication date
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Publication of JP2021500316A publication Critical patent/JP2021500316A/ja
Publication of JP2021500316A5 publication Critical patent/JP2021500316A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2020518798A 2017-10-20 2018-10-19 医薬剤形 Active JP7293209B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762574978P 2017-10-20 2017-10-20
US62/574,978 2017-10-20
PCT/US2018/056724 WO2019079729A1 (en) 2017-10-20 2018-10-19 PHARMACEUTICAL DOSAGE FORMS

Publications (3)

Publication Number Publication Date
JP2021500316A JP2021500316A (ja) 2021-01-07
JP2021500316A5 JP2021500316A5 (enExample) 2021-11-04
JP7293209B2 true JP7293209B2 (ja) 2023-06-19

Family

ID=66173867

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020518798A Active JP7293209B2 (ja) 2017-10-20 2018-10-19 医薬剤形

Country Status (6)

Country Link
US (2) US12053464B2 (enExample)
EP (1) EP3697393A4 (enExample)
JP (1) JP7293209B2 (enExample)
AU (1) AU2018351502B2 (enExample)
CA (1) CA3075292A1 (enExample)
WO (1) WO2019079729A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SA07280459B1 (ar) * 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
AU2018351502B2 (en) * 2017-10-20 2024-09-05 Purdue Pharma L.P. Pharmaceutical dosage forms

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007517050A (ja) 2003-12-31 2007-06-28 アクタビス グループ フルータフェーラグ アトモキセチン製剤
JP2010501543A (ja) 2006-08-25 2010-01-21 パーデュー、ファーマ、リミテッド、パートナーシップ オピオイド鎮痛薬を含む不正改変抵抗性経口医薬剤形
JP2014500304A (ja) 2010-12-22 2014-01-09 パーデュー、ファーマ、リミテッド、パートナーシップ 被覆不正改変抵抗性制御放出剤形
JP2014526497A (ja) 2011-09-16 2014-10-06 パーデュー ファーマ エルピー 不正改変抵抗性医薬製剤
US20160106735A1 (en) 2014-10-17 2016-04-21 Purdue Pharma L.P. Systems and Methods for Treating an Opioid-Induced Adverse Pharmacodynamic Response
JP2017501228A (ja) 2013-12-23 2017-01-12 パーデュー、ファーマ、リミテッド、パートナーシップ オピオイド拮抗薬製剤
JP2017526719A (ja) 2014-09-12 2017-09-14 パーデュー、ファーマ、リミテッド、パートナーシップ オピオイド誘発性多幸症を減弱するためのシステム及び方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486436A (en) * 1982-07-22 1984-12-04 Analgesic Associates Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
US5286493A (en) * 1992-01-27 1994-02-15 Euroceltique, S.A. Stabilized controlled release formulations having acrylic polymer coating
US5472712A (en) * 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
US5914129A (en) * 1996-07-23 1999-06-22 Mauskop; Alexander Analgesic composition for treatment of migraine headaches
US20060240105A1 (en) * 1998-11-02 2006-10-26 Elan Corporation, Plc Multiparticulate modified release composition
ATE340563T1 (de) * 2000-02-04 2006-10-15 Depomed Inc DOSIERUNGSFORM DES TYPS ßHÜLLE UND KERNß MIT EINER WIRKSTOFFFREISETZUNG, DIE SICH DER NULLTEN ORDNUNG ANNÄHERT
SI1299104T1 (sl) * 2000-02-08 2009-10-31 Euro Celtique Sa Oralne formulacije opioidnih agonistov, varne pred zlorabo
CA2510465A1 (en) * 2002-12-18 2004-07-08 Pain Therapeutics Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats
WO2005034859A2 (en) * 2003-10-03 2005-04-21 Elite Laboratories Inc. Extended release formulations of opioids and method of use thereof
EP2380564B1 (en) * 2007-04-04 2014-10-22 Sigmoid Pharma Limited An oral pharmaceutical composition
EP2262367A4 (en) * 2008-03-08 2011-04-20 Theraquest Biosciences Inc PHARMACEUTICAL ORAL COMPOSITIONS OF BUPRENORPHINE AND METHOD FOR THEIR USE
PT2149372E (pt) * 2008-07-31 2014-07-25 Universität Ulm Utilização de opióides do grupo da metadona para o tratamento de pacientes com cancros resistentes
NZ597283A (en) * 2009-06-24 2013-07-26 Egalet Ltd Controlled release formulations
HK1206978A1 (en) * 2012-04-17 2016-01-22 Purdue Pharma L.P. Systems and methods for treating an opioid-induced adverse pharmacodynamic response
US20160220498A1 (en) * 2015-01-29 2016-08-04 Aneesh SONI Fully or partially biodegradable device for controlled drug delivery
JP2017211168A (ja) 2016-05-27 2017-11-30 シャープ株式会社 冷蔵庫、および広告表示プログラム
US20190054024A1 (en) * 2017-08-16 2019-02-21 HUMANWELL PHARMACEUTICAL US, Inc. Solid Dosage Forms
AU2018351502B2 (en) * 2017-10-20 2024-09-05 Purdue Pharma L.P. Pharmaceutical dosage forms

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007517050A (ja) 2003-12-31 2007-06-28 アクタビス グループ フルータフェーラグ アトモキセチン製剤
JP2010501543A (ja) 2006-08-25 2010-01-21 パーデュー、ファーマ、リミテッド、パートナーシップ オピオイド鎮痛薬を含む不正改変抵抗性経口医薬剤形
JP2014500304A (ja) 2010-12-22 2014-01-09 パーデュー、ファーマ、リミテッド、パートナーシップ 被覆不正改変抵抗性制御放出剤形
JP2014526497A (ja) 2011-09-16 2014-10-06 パーデュー ファーマ エルピー 不正改変抵抗性医薬製剤
JP2017501228A (ja) 2013-12-23 2017-01-12 パーデュー、ファーマ、リミテッド、パートナーシップ オピオイド拮抗薬製剤
JP2017526719A (ja) 2014-09-12 2017-09-14 パーデュー、ファーマ、リミテッド、パートナーシップ オピオイド誘発性多幸症を減弱するためのシステム及び方法
US20160106735A1 (en) 2014-10-17 2016-04-21 Purdue Pharma L.P. Systems and Methods for Treating an Opioid-Induced Adverse Pharmacodynamic Response

Also Published As

Publication number Publication date
WO2019079729A1 (en) 2019-04-25
CA3075292A1 (en) 2019-04-25
EP3697393A1 (en) 2020-08-26
US20250017917A1 (en) 2025-01-16
JP2021500316A (ja) 2021-01-07
AU2018351502B2 (en) 2024-09-05
AU2018351502A1 (en) 2020-03-26
EP3697393A4 (en) 2021-10-13
US20210205295A1 (en) 2021-07-08
US12053464B2 (en) 2024-08-06

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