JP7292213B2 - Ｃｒｉｓｐｒ／ｃｐｆ１を用いる、ｔ細胞における遺伝子編集のための組成物および方法 - Google Patents

Ｃｒｉｓｐｒ／ｃｐｆ１を用いる、ｔ細胞における遺伝子編集のための組成物および方法 Download PDF

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JP7292213B2
JP7292213B2 JP2019560197A JP2019560197A JP7292213B2 JP 7292213 B2 JP7292213 B2 JP 7292213B2 JP 2019560197 A JP2019560197 A JP 2019560197A JP 2019560197 A JP2019560197 A JP 2019560197A JP 7292213 B2 JP7292213 B2 JP 7292213B2
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ヤンビン チャオ
ジャンタオ レン
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ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
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JP2019560197A 2017-05-04 2018-05-02 Ｃｒｉｓｐｒ／ｃｐｆ１を用いる、ｔ細胞における遺伝子編集のための組成物および方法 Active JP7292213B2 (ja)

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JP2023092842A JP7622138B2 (ja) 2017-05-04 2023-06-06 Ｃｒｉｓｐｒ／ｃｐｆ１を用いる、ｔ細胞における遺伝子編集のための組成物および方法
JP2025005127A JP2025061285A (ja) 2017-05-04 2025-01-15 Ｃｒｉｓｐｒ／ｃｐｆ１を用いる、ｔ細胞における遺伝子編集のための組成物および方法

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US201762501371P 2017-05-04 2017-05-04
US62/501,371 2017-05-04
PCT/US2018/030644 WO2018204493A1 (en) 2017-05-04 2018-05-02 Compositions and methods for gene editing in t cells using crispr/cpf1

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JP2023092842A Active JP7622138B2 (ja) 2017-05-04 2023-06-06 Ｃｒｉｓｐｒ／ｃｐｆ１を用いる、ｔ細胞における遺伝子編集のための組成物および方法
JP2025005127A Pending JP2025061285A (ja) 2017-05-04 2025-01-15 Ｃｒｉｓｐｒ／ｃｐｆ１を用いる、ｔ細胞における遺伝子編集のための組成物および方法

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JP2025005127A Pending JP2025061285A (ja) 2017-05-04 2025-01-15 Ｃｒｉｓｐｒ／ｃｐｆ１を用いる、ｔ細胞における遺伝子編集のための組成物および方法

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CA (1) CA3062165A1 (enExample)
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US9359599B2 (en) 2013-08-22 2016-06-07 President And Fellows Of Harvard College Engineered transcription activator-like effector (TALE) domains and uses thereof
US9340800B2 (en) 2013-09-06 2016-05-17 President And Fellows Of Harvard College Extended DNA-sensing GRNAS
US9388430B2 (en) 2013-09-06 2016-07-12 President And Fellows Of Harvard College Cas9-recombinase fusion proteins and uses thereof
US9526784B2 (en) 2013-09-06 2016-12-27 President And Fellows Of Harvard College Delivery system for functional nucleases
US9840699B2 (en) 2013-12-12 2017-12-12 President And Fellows Of Harvard College Methods for nucleic acid editing
WO2016022363A2 (en) 2014-07-30 2016-02-11 President And Fellows Of Harvard College Cas9 proteins including ligand-dependent inteins
IL258821B (en) 2015-10-23 2022-07-01 Harvard College Nucleobase editors and their uses
KR20250103795A (ko) 2016-08-03 2025-07-07 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 아데노신 핵염기 편집제 및 그의 용도
CA3033327A1 (en) 2016-08-09 2018-02-15 President And Fellows Of Harvard College Programmable cas9-recombinase fusion proteins and uses thereof
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JP7588390B2 (ja) 2016-10-14 2024-11-22 プレジデント アンド フェローズ オブ ハーバード カレッジ 核酸塩基エディターのａａｖ送達
WO2018119359A1 (en) 2016-12-23 2018-06-28 President And Fellows Of Harvard College Editing of ccr5 receptor gene to protect against hiv infection
CN110662556A (zh) 2017-03-09 2020-01-07 哈佛大学的校长及成员们 癌症疫苗
WO2018165504A1 (en) 2017-03-09 2018-09-13 President And Fellows Of Harvard College Suppression of pain by gene editing
JP2020510439A (ja) 2017-03-10 2020-04-09 プレジデント アンド フェローズ オブ ハーバード カレッジ シトシンからグアニンへの塩基編集因子
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WO2018209320A1 (en) 2017-05-12 2018-11-15 President And Fellows Of Harvard College Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation
JP2020534795A (ja) 2017-07-28 2020-12-03 プレジデント アンド フェローズ オブ ハーバード カレッジ ファージによって支援される連続的進化（ｐａｃｅ）を用いて塩基編集因子を進化させるための方法および組成物
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CN111770994B (zh) * 2017-10-02 2025-03-18 基因编辑有限公司 修饰的cpf1引导rna
KR20250107288A (ko) 2017-10-16 2025-07-11 더 브로드 인스티튜트, 인코퍼레이티드 아데노신 염기 편집제의 용도
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JP2020518256A (ja) 2020-06-25
JP2025061285A (ja) 2025-04-10
EP3619302A1 (en) 2020-03-11
US20240316107A1 (en) 2024-09-26
US20200054679A1 (en) 2020-02-20
US12029760B2 (en) 2024-07-09
CA3062165A1 (en) 2018-11-08
EP3619302A4 (en) 2021-01-20
JP2023113798A (ja) 2023-08-16
CN110785489A (zh) 2020-02-11
WO2018204493A1 (en) 2018-11-08
JP7622138B2 (ja) 2025-01-27

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