JP7290288B2 - 免疫不全及び自己免疫疾患を治療するための、造血幹細胞でｆｏｘｐ３を発現するレンチウイルスベクター - Google Patents

免疫不全及び自己免疫疾患を治療するための、造血幹細胞でｆｏｘｐ３を発現するレンチウイルスベクター Download PDF

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JP7290288B2
JP7290288B2 JP2020511428A JP2020511428A JP7290288B2 JP 7290288 B2 JP7290288 B2 JP 7290288B2 JP 2020511428 A JP2020511428 A JP 2020511428A JP 2020511428 A JP2020511428 A JP 2020511428A JP 7290288 B2 JP7290288 B2 JP 7290288B2
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foxp3
vector
expression
panel
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ドナルド・ビー・コーン
マリア・グラツィア・ロンカローロ
ロジャー・ピー・ホリス
ケイトリン・イー・マシウク
ローザ・バチェッタ
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University of California San Diego UCSD
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JP2020511428A 2017-08-22 2018-08-22 免疫不全及び自己免疫疾患を治療するための、造血幹細胞でｆｏｘｐ３を発現するレンチウイルスベクター Active JP7290288B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762548891P 2017-08-22 2017-08-22
US62/548,891 2017-08-22
PCT/US2018/047586 WO2019040655A1 (en) 2017-08-22 2018-08-22 LENTIVIRAL VECTORS EXPRESSING FOXP3 IN HEMATOPOIETIC STEM CELLS TO TREAT IMMUNITY DEFICIENCIES AND AUTOIMMUNE DISEASES

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JP2020533969A JP2020533969A (ja) 2020-11-26
JP2020533969A5 JP2020533969A5 (OSRAM) 2021-09-30
JP7290288B2 true JP7290288B2 (ja) 2023-06-13

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US (2) US12060566B2 (OSRAM)
EP (1) EP3672617A4 (OSRAM)
JP (1) JP7290288B2 (OSRAM)
KR (1) KR102780121B1 (OSRAM)
WO (1) WO2019040655A1 (OSRAM)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016427822B2 (en) 2016-10-31 2025-01-23 Seattle Children's Hospital (dba Seattle Children's Research Institute) Method for treating autoimmune disease using CD4 T-cells with engineered stabilization of expression of endogennous FOXP3 gene
JP7290288B2 (ja) 2017-08-22 2023-06-13 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 免疫不全及び自己免疫疾患を治療するための、造血幹細胞でｆｏｘｐ３を発現するレンチウイルスベクター
CA3091491A1 (en) * 2018-04-27 2019-10-31 Seattle Children's Hospital (dba Seattle Children's Research Institute) Expression of human foxp3 in gene edited t cells
CA3091688A1 (en) * 2018-04-27 2019-10-31 Seattle Children's Hospital (dba Seattle Children's Research Institute) Expression of foxp3 in edited cd34+ cells
US20220168394A1 (en) * 2019-04-23 2022-06-02 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods of inducing or restoring immune tolerance
CA3140910A1 (en) * 2019-06-07 2020-12-10 The Board Of Trustees Of The Leland Stanford Junior University Foxp3 engineered cd4+ t cells for use in treg-based immunotherapy
WO2021028359A1 (en) * 2019-08-09 2021-02-18 Sangamo Therapeutics France Controlled expression of chimeric antigen receptors in t cells
EP4410965A4 (en) * 2021-09-27 2025-09-24 Univ Kyoto T LYMPHOCYTE PRODUCTION PROCESS
CN118946661A (zh) * 2022-02-04 2024-11-12 国立大学法人京都大学 T细胞生产方法
WO2023182328A1 (ja) * 2022-03-23 2023-09-28 国立大学法人京都大学 制御性ｔ細胞の製造方法
KR20250077533A (ko) * 2022-09-26 2025-05-30 고쿠리츠 다이가쿠 호진 교토 다이가쿠 T 세포 제조 방법

Citations (1)

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JP2004208548A (ja) 2002-12-27 2004-07-29 Institute Of Physical & Chemical Research 免疫反応の抗原特異的抑制

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ATE405586T1 (de) 2001-05-08 2008-09-15 Darwin Molecular Corp Verfahren zur regulierung der immunfunktion in primaten unter verwendung des foxp3-proteins
WO2008141282A2 (en) * 2007-05-11 2008-11-20 The Regents Of The University Of Michigan Materials and methods for foxp3 tumor suppression
US20140065110A1 (en) * 2012-08-31 2014-03-06 The Regents Of The University Of California Genetically modified msc and therapeutic methods
US9663564B2 (en) * 2013-03-15 2017-05-30 The Regents Of The University Of California Vectors and methods to treat ischemia
WO2014121840A1 (en) 2013-02-07 2014-08-14 Medizinische Hochschule Hannover Induced dendritic cells and uses thereof
GB201318347D0 (en) * 2013-10-16 2013-11-27 Ucl Business Plc Retroviral vectors
KR102796744B1 (ko) 2015-06-09 2025-04-15 에디타스 메디신, 인코포레이티드 이식의 개선을 위한 crispr/cas-관련 방법 및 조성물
JP7290288B2 (ja) * 2017-08-22 2023-06-13 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 免疫不全及び自己免疫疾患を治療するための、造血幹細胞でｆｏｘｐ３を発現するレンチウイルスベクター

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
JP2004208548A (ja) 2002-12-27 2004-07-29 Institute Of Physical & Chemical Research 免疫反応の抗原特異的抑制

Non-Patent Citations (3)

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J. Exp. Med.，2007年，Vol. 204, No. 7，pp.1543-1551
Nat. Immunol.，2008年，Vol. 9, No. 2，pp.194-202
Nature，2010年，Vol. 463，pp.808-812

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KR102780121B1 (ko) 2025-03-12
US20200347404A1 (en) 2020-11-05
US12060566B2 (en) 2024-08-13
EP3672617A1 (en) 2020-07-01
WO2019040655A1 (en) 2019-02-28
JP2020533969A (ja) 2020-11-26
US20240336935A1 (en) 2024-10-10
EP3672617A4 (en) 2021-06-23
KR20200054210A (ko) 2020-05-19

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