JP7285537B2 - Ｃａ ｉｘ標的ｎｉｒ色素及びそれらの使用 - Google Patents

Ｃａ ｉｘ標的ｎｉｒ色素及びそれらの使用 Download PDF

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JP7285537B2
JP7285537B2 JP2018548414A JP2018548414A JP7285537B2 JP 7285537 B2 JP7285537 B2 JP 7285537B2 JP 2018548414 A JP2018548414 A JP 2018548414A JP 2018548414 A JP2018548414 A JP 2018548414A JP 7285537 B2 JP7285537 B2 JP 7285537B2
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tumor
compound
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エー． クララットナ，スミス
ガガレ，プラビン
カンデュルル，アナンダ
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オン ターゲット ラボラトリーズ エルエルシー
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/583—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label
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    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
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JP2018548414A 2016-03-16 2017-03-16 Ｃａ ｉｘ標的ｎｉｒ色素及びそれらの使用 Active JP7285537B2 (ja)

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US201662309412P 2016-03-16 2016-03-16
US62/309,412 2016-03-16
PCT/US2017/022824 WO2017161197A1 (en) 2016-03-16 2017-03-16 Ca ix-target nir dyes and their uses

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JP2019512500A5 JP2019512500A5 (https=) 2020-04-23
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US (2) US10557854B2 (https=)
EP (1) EP3430383B1 (https=)
JP (1) JP7285537B2 (https=)
KR (1) KR102342319B1 (https=)
CN (1) CN109791107B (https=)
AU (1) AU2017234681B2 (https=)
BR (1) BR112018068142B1 (https=)
ES (1) ES2989466T3 (https=)
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US11555821B2 (en) 2016-03-16 2023-01-17 On Target Laboratories, Inc. CA IX-NIR dyes and their uses
CN111225688B (zh) * 2017-08-22 2025-06-17 普渡研究基金会 靶向碳酸酐酶阳性癌症的基于fbsa的治疗和放射性成像缀合物
WO2019133914A1 (en) * 2017-12-29 2019-07-04 Wayne State University Method of treatment for solid tumors containing hypoxia and/or stroma features
WO2020131980A1 (en) * 2018-12-19 2020-06-25 Purdue Research Foundation Carbonic anhydrase inhibitors and antibiotics against multidrug resistant bacteria
CN110790724B (zh) * 2019-09-20 2023-01-31 中山大学 一种选择性碳酸酐酶抑制剂及其合成方法和应用
US20210353151A1 (en) * 2020-05-12 2021-11-18 On Target Laboratories, LLC Targeted fluorescent markers in combination with a flexible probe
EP4247436A4 (en) * 2020-11-18 2024-10-16 On Target Laboratories, LLC NEAR-INFRARED II PROBES AS HIGH-AFFINE TARGETING IMAGING AGENTS AND USES THEREOF
US20240000946A1 (en) * 2020-12-03 2024-01-04 Vilnius University Carbonic anhydrase inhibitors synthesized on interconnecting linker chains
CA3217981A1 (en) * 2021-05-14 2022-11-17 Philip Low Folate receptor-targeted conjugates with brush border membrane enzyme-cleavable linkers and methods of use in imaging and treating cancer
WO2023081301A1 (en) * 2021-11-05 2023-05-11 On Target Laboratories, LLC Fibroblast activation protein targeted dyes their related uses
CA3243979A1 (en) * 2022-02-11 2025-04-30 C-Biomex Co., Ltd. Peptide ligand targeting carbonic anhydrase IX, peptide construction comprising it, and associated uses
EP4562099A1 (en) 2022-07-28 2025-06-04 Bracco Imaging SPA Ca-ix targeting fluorescent probes
CN119325492A (zh) 2022-07-28 2025-01-17 伯拉考成像股份公司 靶向ca-ix的荧光探针
CN119490505A (zh) * 2023-08-16 2025-02-21 新斗生物科技(苏州)有限公司 一种含叶酸类化合物的组合物及近红外荧光捕获系统

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