JP7280199B2 - デジタルマイクロ流体チップ用の駆動方法及び駆動システム - Google Patents

デジタルマイクロ流体チップ用の駆動方法及び駆動システム Download PDF

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JP7280199B2
JP7280199B2 JP2019569427A JP2019569427A JP7280199B2 JP 7280199 B2 JP7280199 B2 JP 7280199B2 JP 2019569427 A JP2019569427 A JP 2019569427A JP 2019569427 A JP2019569427 A JP 2019569427A JP 7280199 B2 JP7280199 B2 JP 7280199B2
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JP2020534991A (ja
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▲鳳▼ ▲龍▼
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BOE Technology Group Co Ltd
Beijing BOE Optoelectronics Technology Co Ltd
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BOE Technology Group Co Ltd
Beijing BOE Optoelectronics Technology Co Ltd
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0673—Handling of plugs of fluid surrounded by immiscible fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0424—Dielectrophoretic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0427—Electrowetting

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
JP2019569427A 2017-09-29 2018-07-09 デジタルマイクロ流体チップ用の駆動方法及び駆動システム Active JP7280199B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201710910461.6A CN107617451B (zh) 2017-09-29 2017-09-29 一种微流控芯片的驱动方法和驱动系统
CN201710910461.6 2017-09-29
PCT/CN2018/094943 WO2019062267A1 (zh) 2017-09-29 2018-07-09 用于数字微流控芯片的驱动方法和驱动系统

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JP2020534991A JP2020534991A (ja) 2020-12-03
JP2020534991A5 JP2020534991A5 (enExample) 2021-12-16
JP7280199B2 true JP7280199B2 (ja) 2023-05-23

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US (1) US11446656B2 (enExample)
EP (1) EP3689463A4 (enExample)
JP (1) JP7280199B2 (enExample)
CN (1) CN107617451B (enExample)
WO (1) WO2019062267A1 (enExample)

Families Citing this family (8)

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Publication number Priority date Publication date Assignee Title
CN107617451B (zh) * 2017-09-29 2019-06-04 京东方科技集团股份有限公司 一种微流控芯片的驱动方法和驱动系统
CN108654711B (zh) * 2018-06-07 2020-03-31 西南科技大学 一种降低电场下固液界面粘-滑行为的方法
CN109126917B (zh) * 2018-10-09 2020-04-10 京东方科技集团股份有限公司 微流控芯片及其驱动方法
CN109622085B (zh) 2019-01-31 2021-12-24 京东方科技集团股份有限公司 微流控芯片的驱动方法及其装置、微流控系统
CN110010086B (zh) 2019-03-29 2020-12-22 上海中航光电子有限公司 电润湿面板的驱动方法
CN112415357B (zh) * 2019-08-21 2025-09-16 佛山奥素博新科技有限公司 数字微流控设备与dmf驱动系统连接的检测方法、系统
CN113805035B (zh) * 2020-06-17 2025-08-22 佛山奥素博新科技有限公司 一种数字微流控系统的检测电路和检测方法
CN120576153B (zh) * 2024-11-14 2025-11-14 康沃思(天津)生物科技有限公司 基于声束流实现微水锤效应的方法及装置

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012163956A (ja) 2011-02-02 2012-08-30 Sharp Corp アクティブマトリクス装置
JP2012176397A (ja) 2011-01-18 2012-09-13 Sharp Corp 誘電体上のアクティブマトリクス液滴駆動およびその駆動方法
US20140166484A1 (en) 2012-12-17 2014-06-19 Taiwan Semiconductor Manufacturing Company, Ltd. Systems and Methods for an Integrated Bio-Entity Manipulation and Processing Semiconductor Device
US20160296929A1 (en) 2015-04-10 2016-10-13 University Of Macau Electrode-voltage waveform for droplet-velocity and chip-lifetime improvements of digital microfluidic systems
WO2017007757A1 (en) 2015-07-06 2017-01-12 Illumina, Inc. Balanced ac modulation for driving droplet operations electrodes

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3791999B2 (ja) 1997-03-24 2006-06-28 株式会社アドバンス 液体微粒子ハンドリング装置
CN102175744A (zh) 2011-01-06 2011-09-07 复旦大学 一种数字微流控技术的电化学传感器芯片
CN102350380B (zh) * 2011-09-26 2014-04-02 复旦大学 一种透明单平面单极性数字微流体芯片及其控制方法
CN102600919B (zh) * 2012-03-20 2014-10-01 复旦大学 一种限制数字微流控芯片液滴单向输运的方法
CN102879453B (zh) 2012-09-04 2015-08-26 吴传勇 基于电泳来操控液体中的带电粒子的方法及器件
CN102824933B (zh) * 2012-09-20 2014-09-03 复旦大学 一种单向液滴输运的数字微流芯片电极配置方法
US9254485B2 (en) * 2012-12-17 2016-02-09 Taiwan Semiconductor Manufacturing Company, Ltd. Systems and methods for an integrated bio-entity manipulation and processing device
CN104035796A (zh) * 2014-06-13 2014-09-10 苏州大学 一种ewod芯片液滴驱动方法及系统
CN105233887B (zh) * 2015-08-31 2017-06-23 中国科学院深圳先进技术研究院 一种基于介电润湿的微液滴驱动器件及其制备方法
CN107617451B (zh) * 2017-09-29 2019-06-04 京东方科技集团股份有限公司 一种微流控芯片的驱动方法和驱动系统

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012176397A (ja) 2011-01-18 2012-09-13 Sharp Corp 誘電体上のアクティブマトリクス液滴駆動およびその駆動方法
JP2012163956A (ja) 2011-02-02 2012-08-30 Sharp Corp アクティブマトリクス装置
US20140166484A1 (en) 2012-12-17 2014-06-19 Taiwan Semiconductor Manufacturing Company, Ltd. Systems and Methods for an Integrated Bio-Entity Manipulation and Processing Semiconductor Device
US20160296929A1 (en) 2015-04-10 2016-10-13 University Of Macau Electrode-voltage waveform for droplet-velocity and chip-lifetime improvements of digital microfluidic systems
WO2017007757A1 (en) 2015-07-06 2017-01-12 Illumina, Inc. Balanced ac modulation for driving droplet operations electrodes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Lab.Chip.，2007年，Vol.7，P.1330-1335

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Publication number Publication date
US20210362148A1 (en) 2021-11-25
CN107617451B (zh) 2019-06-04
EP3689463A1 (en) 2020-08-05
US11446656B2 (en) 2022-09-20
WO2019062267A1 (zh) 2019-04-04
CN107617451A (zh) 2018-01-23
EP3689463A4 (en) 2021-11-24
JP2020534991A (ja) 2020-12-03

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