JP7193147B2 - ヤヌス液滴を用いた検体の検出 - Google Patents

ヤヌス液滴を用いた検体の検出 Download PDF

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JP7193147B2
JP7193147B2 JP2019515484A JP2019515484A JP7193147B2 JP 7193147 B2 JP7193147 B2 JP 7193147B2 JP 2019515484 A JP2019515484 A JP 2019515484A JP 2019515484 A JP2019515484 A JP 2019515484A JP 7193147 B2 JP7193147 B2 JP 7193147B2
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janus
janus droplets
analyte
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droplets
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JP2019533148A (ja
JP2019533148A5 (enExample
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ティモシー エム． スウェイガー，
チファン ジャン，
スチョル サヴァガトラップ，
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Massachusetts Institute of Technology
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/5432—Liposomes or microcapsules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7783—Transmission, loss

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2019515484A 2016-09-19 2017-09-19 ヤヌス液滴を用いた検体の検出 Active JP7193147B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15/269,543 US10060913B2 (en) 2016-09-19 2016-09-19 Systems including janus droplets capable of binding an analyte and changing orientation to provide a detectable change
US15/269,543 2016-09-19
PCT/US2017/052209 WO2018053481A1 (en) 2016-09-19 2017-09-19 Detection of analytes with janus droplets

Publications (3)

Publication Number Publication Date
JP2019533148A JP2019533148A (ja) 2019-11-14
JP2019533148A5 JP2019533148A5 (enExample) 2020-11-12
JP7193147B2 true JP7193147B2 (ja) 2022-12-20

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JP2019515484A Active JP7193147B2 (ja) 2016-09-19 2017-09-19 ヤヌス液滴を用いた検体の検出

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US (2) US10060913B2 (enExample)
EP (1) EP3516393B1 (enExample)
JP (1) JP7193147B2 (enExample)
WO (1) WO2018053481A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210041425A1 (en) * 2014-10-31 2021-02-11 Massachusetts Institute Of Technology Complex liquid crystal droplets
WO2016070016A1 (en) 2014-10-31 2016-05-06 Massachusetts Institute Of Technology Compositions and methods for forming emulsions
US11119098B2 (en) 2014-10-31 2021-09-14 Massachusetts Institute Of Technology Systems including Janus droplets
US20190170737A1 (en) 2016-09-19 2019-06-06 Massachusetts Institute Of Technology Systems including janus droplets
US11899013B2 (en) * 2019-06-25 2024-02-13 Canon Medical Systems Corporation Method of detecting or quantifying detection target in specimen, composite particle, and reagent
US12274993B2 (en) 2019-09-18 2025-04-15 Massachusetts Institute Of Technology Systems and methods for affecting interactions of electromagnetic radiation with janus droplets for sensitive detection of species
KR102795597B1 (ko) * 2021-04-16 2025-04-15 장지환 야누스 입자 정렬을 이용한 진단 방법 및 진단장치

Citations (3)

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JP2011522616A (ja) 2008-06-04 2011-08-04 セブンス センス バイオシステムズ，インコーポレーテッド シングルステップ診断のための組成物および方法
US20120288852A1 (en) 2010-01-15 2012-11-15 Richard Willson Force Mediated Assays
US20160151756A1 (en) 2014-10-31 2016-06-02 Massachusetts Institute Of Technology Compositions and methods for arranging colloid phases

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US4912034A (en) * 1987-09-21 1990-03-27 Biogenex Laboratories Immunoassay test device and method
BR9205819A (pt) 1991-03-28 1994-06-07 Micro Vesicular Systems Emulsoes de água em óleo contendo vesículas de lipídio
US5332661A (en) * 1991-07-31 1994-07-26 Abbott Laboratories Reagents and methods for the quantification of total doxepins in biological fluids
WO1993008472A1 (en) * 1991-10-15 1993-04-29 Multilyte Limited Binding assay employing labelled reagent
US5573994A (en) 1994-05-13 1996-11-12 University Of Cincinnati Superabsorbent foams, and method for producing the same
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AU7421201A (en) 2000-06-05 2001-12-17 Syngenta Limited Novel emulsions
US7625951B2 (en) 2000-07-13 2009-12-01 University Of Kentucky Research Foundation Stimuli-responsive hydrogel microdomes integrated with genetically engineered proteins for high-throughput screening of pharmaceuticals
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JP3595805B2 (ja) 2001-08-07 2004-12-02 キヤノン株式会社 刺激応答性組成物、並びに該組成物を用いた画像形成方法および装置
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US20120288852A1 (en) 2010-01-15 2012-11-15 Richard Willson Force Mediated Assays
US20160151756A1 (en) 2014-10-31 2016-06-02 Massachusetts Institute Of Technology Compositions and methods for arranging colloid phases

Also Published As

Publication number Publication date
EP3516393A1 (en) 2019-07-31
US20190212333A1 (en) 2019-07-11
JP2019533148A (ja) 2019-11-14
US20180080927A1 (en) 2018-03-22
EP3516393B1 (en) 2022-02-09
US10060913B2 (en) 2018-08-28
WO2018053481A1 (en) 2018-03-22

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