JP7070880B2 - Effervescent skin external therapy kit - Google Patents

Description

The present invention relates to a kit for obtaining an effervescent skin external preparation.

Conventionally, for the purpose of beauty, a gel-type effervescent skin external preparation which is used by mixing carbonic acid and acid in the presence of water and a thickener to generate carbon dioxide gas has been proposed (for example, patent). See Document 1).

Japanese Patent No. 4695980

However, improvement of skin condition such as increasing the amount of water in the skin, reducing the amount of water evaporation, and improving the elasticity of the skin, as well as usability, stability, and usability have not been sufficiently studied. Furthermore, little consideration has been given to achieving both excellent skin condition improvement and usability.

In the present invention, various studies have been conducted on effervescent skin external preparations for improving the skin condition and obtaining a composition having a good usability.
As a result, they have found that the above problems can be solved by blending two or more kinds of thickeners in combination, and have completed the present invention.

The present invention is a kit for obtaining an effervescent skin external preparation obtained by mixing an acidic substance, a carbonic acid gas generating substance that reacts with the acidic substance to generate carbonic acid gas, a thickener, and water. It is intended to provide a kit in which two or more kinds of the thickeners are used and the composition is any one of the following (1) to (3).
(1) A solid composition (A) containing an acidic substance and a composition (B) containing water, a thickener, and a carbon dioxide gas generating substance.
(2) A solid composition (C) containing an acidic substance and a carbon dioxide gas generating substance, and a composition (D) containing water and a thickener.
(3) A solid composition (E) containing a carbon dioxide gas generating substance and a composition (F) containing water, a thickener, and an acidic substance.
(However, the thickeners of (B), (D), and (F) are excluded from the following combinations. Sodium alginate and xanthan gum, cellulose gum, hydroxypropylmethyl cellulose, carbomer, polyvinyl alcohol, or bentonite. Combination of xanthan gum and cellulose gum, hydroxypropylmethylcellulose or bentonite, or combination of cellulose gum and hydroxypropylmethylcellulose or carbomer)

The present invention also provides the kit according to claim 1, wherein one or both of the compositions constituting the kits (1) to (3) further contain a polyhydric alcohol. ..

Further, in the present invention, among the kits (1) to (3), the solid composition ((A), (C), (E)) is in the form of powder and contains water and a thickener. It is an object of the present invention to provide a kit for obtaining an effervescent skin external preparation according to claim 1 or 2, wherein the substance ((B), (D), (F)) is in the form of a gel.

Further, the present invention is characterized in that the thickeners used in the kits (1) to (3) are two or more selected from natural polysaccharides and / or cellulosic thickeners. It provides a kit for obtaining.

According to the present invention, by blending two or more kinds of thickeners in combination, the effect of increasing the water content of the skin, reducing the water evaporation amount, improving the skin elasticity, etc. is achieved, and the skin condition is improved. It is possible to provide a kit for obtaining an effervescent skin external preparation which is excellent in usability, safety and stability such as ease of mixing and application, and has a good usability.

FIG. 1 shows the results of keratin water content measurement in Comparative Examples and Examples. FIG. 2 shows the results of water evaporation measurement of Comparative Examples and Examples. FIG. 3 shows the results of elasticity measurement of Comparative Examples and Examples.

Hereinafter, a kit for obtaining an effervescent skin external preparation of the present invention (hereinafter, also referred to as “kit”) will be described based on a preferred embodiment thereof.

The kit of the present invention has any of the following configurations (1) to (3).
(1) A solid composition (A) containing an acidic substance and a composition (B) containing water, a thickener, and a carbon dioxide gas generating substance.
(2) A solid composition (C) containing an acidic substance and a carbon dioxide gas generating substance, and a composition (D) containing water and a thickener.
(3) A solid composition (E) containing a carbon dioxide gas generating substance and a composition (F) containing water, a thickener, and an acidic substance.
In the present specification, the solid composition of (1) is (A), the water-containing composition of (1) is (B), the solid composition of (2) is (C), and the water-containing composition of (2). The substance is also referred to as (D), the solid composition of (3) is also referred to as (E), and the hydrous group organism of (3) is also referred to as (F).

The effervescent skin external preparation obtained by using the kit of the present invention can be used in any form of cosmetics, quasi-drugs, and pharmaceuticals, but from the viewpoint of efficacy and usability, cosmetics or quasi-drugs. It is preferable to use it as a quasi-drug (quasi-drug).

In addition, the effervescent skin external preparation obtained by using the kit of the present invention can be applied externally to the skin including the scalp and hair, and can be used as a pack, a hair restorer, a washing pigment, a cleansing agent, a lotion, a milky lotion, and a beauty gel. , Shampoo, conditioner, etc., can be used in various forms. When it is washed away, it is preferably used in packs, washing pigments, cleansing agents, shampoos, conditioners and the like.

First, each of the main constituents used in the kit for obtaining the effervescent skin external preparation of the present invention will be described.

<Acid substance>
The acidic substance used in the present invention may be any inorganic acid or organic acid that can be usually used as an external preparation, and one or more of these may be used.

Examples of the inorganic acid include phosphoric acid, potassium dihydrogen phosphate, sodium dihydrogen phosphate, sodium sulfite, potassium sulfite, sodium pyrosulfate, potassium pyrosulfate, sodium acid hexamethaphosphate, potassium hexametaphosphate, and sodium pyrophosphate. , Acidic potassium pyrophosphate, sulfamic acid and the like.

Examples of the organic acid include linear fatty acids such as formic acid, acetic acid, propionic acid, butyric acid and valeric acid or salts thereof, oxalic acid, malonic acid, succinic acid, glutaric acid, adipic acid, pimelic acid, fumaric acid and maleic acid. Dicarboxylic acids such as phthalic acid, isophthalic acid and terephthalic acid or salts thereof, acidic amino acids such as glutamate and aspartic acid or salts thereof, glycolic acid, malic acid, tartrate acid, citric acid, lactic acid, hydroxyacrylic acid, α-oxybutyric acid, Examples thereof include oxy acids such as glyceric acid, tartronic acid, salicylic acid, galvanic acid, tropic acid, ascorbic acid and gluconic acid, or salts thereof.

Of these, citric acid, ascorbic acid, malic acid and succinic acid are preferable from the viewpoint of safety and solubility in water.

The content of the acidic substance in (A), (C), and (F) of the present invention is 0.01 part by mass or more and 30 parts by mass or less with respect to 100 parts by mass of the total amount of the two agents of the corresponding kit. It is preferably 0.05 parts by mass or more and 20 parts by mass or less. The amount of the external skin preparation referred to in the present specification may be the amount at the start of mixing in which the components of each kit are mixed.

The content of the acidic substance in (A) of the present invention is preferably 0.1% by mass or more and 90% by mass or less, and more preferably 0.5% by mass or more and 80% by mass or less.
The content of the acidic substance in (C) of the present invention is preferably 0.01% by mass or more and 50% by mass or less, and more preferably 0.05% by mass or more and 40% by mass or less.
Further, the content of the acidic substance in (F) of the present invention is preferably 0.01% by mass or more and 30% by mass or less, and further preferably 0.05% by mass or more and 20% by mass or less.

<Carbon dioxide generator>
The carbon dioxide gas generating substance used in the present invention may be any substance that reacts with the acidic substance to generate carbon dioxide.

Examples of carbon dioxide generating substances include carbonates such as sodium carbonate, calcium carbonate, potassium carbonate, magnesium carbonate, and sodium sesquicarbonate, ammonium hydrogencarbonate, potassium hydrogencarbonate, sodium hydrogencarbonate, lithium hydrogencarbonate, cesium hydrogencarbonate, and magnesium hydrogencarbonate. , Bicarbonates such as calcium hydrogen carbonate and the like, and one or more of these are used. Among these, sodium hydrogencarbonate is more preferable in that hydrogencarbonate can be preferably used and moderate foaming power can be realized.

The content of the carbon dioxide generating substance in (B), (C), and (E) of the present invention is 0.01 part by mass or more and 30 parts by mass with respect to 100 parts by mass of the total amount of the two agents of the corresponding kit. The amount is preferably 0.05 parts by mass or more, and more preferably 20 parts by mass or less.

The content of the carbon dioxide generating substance in (B) of the present invention is preferably 0.01% by mass or more and 30% by mass or less, and more preferably 0.05% by mass or more and 20% by mass or less.
The content of the carbon dioxide generating substance in (C) of the present invention is preferably 0.01% by mass or more and 50% by mass or less, and more preferably 0.05% by mass or more and 40% by mass or less.
The content of the carbon dioxide gas generating substance in (E) of the present invention is preferably 0.1% by mass or more and 90% by mass or less, and more preferably 0.5% by mass or more and 80% by mass or less.

<Thickener>
One of the features of the kit for obtaining the effervescent skin external preparation of the present invention is that two or more kinds of thickeners are combined and blended. Such thickeners are described in detail below.
Examples of the thickener used in the present invention include various ones that can be used in the fields of cosmetics and pharmaceuticals. For example, natural polysaccharides, cellulosic polymers, synthetic polymers, clay minerals and the like can be used.

The natural polysaccharide used in the present invention is a polysaccharide derived from animals and plants or microbial fermentation, and refers to a sugar that has not been processed and whose purpose of processing is to reduce the size of the sugar. Polysaccharides will be slightly reduced in size during normal purification procedures. Such sugars are still natural. Only when the polysaccharide is subjected to size reduction techniques is it considered unnatural.

Specifically, xanthan gum, succinoglycan, carrageenan, guar gum, locust bean gum, galactan, arabic gum, tragant gum, tamarind gum, agar, agarose, mannan, curdran, alginic acid or its salts, arabic rubber, pectin, quinceed. , Starch, algae colloid, alkasilan, chondroitin sulfate or salts thereof, chitosan and its derivatives, nucleic acids or salts thereof, ribonucleic acid or salts thereof, casein, collagen, gelatin, albumin, fibroin, elastin, keratin, sericin and the like. Examples include proteins, hyaluronic acid or salts thereof, mucopolysaccharides such as chondroitin sulfate, and the like. Among these, xanthan gum, carrageenan, tamarind gum, alginic acid or salts thereof are preferable from the viewpoint of achieving both an excellent feeling of use and an action of improving skin condition.

The cellulosic polymer used in the present invention is a polymer composed of cellulose or a derivative thereof as a unit. Specific examples thereof include carboxymethyl cellulose or salts thereof, methyl cellulose, ethyl cellulose, propyl cellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl methyl cellulose, sulfonated cellulose derivatives and the like. Among these, carboxymethyl cellulose or salts thereof, hydroxyethyl cellulose, and hydroxypropylmethyl cellulose are preferable from the viewpoint of achieving both an excellent feeling of use and an action of improving the skin condition.

The synthetic polymer used in the present invention is a polymer artificially synthesized using a monomer as a constituent unit. Specifically, carboxyvinyl polymers, vinyl polymers such as polyvinyl alcohol, acrylic acid / alkyl methacrylate copolymers, acrylic acid / alkyl acrylate cross polymers, acrylic acid polymers such as polyacrylic acid, polyacrylamide, Examples thereof include acrylamide-based polymers such as polyalkylacrylamide / polyacrylamide copolymers, Pluronic, and (PEG-240 / decyltetradeceth-20 / HDI) copolymers.

The clay mineral used in the present invention refers to a substance usually known as a main component mineral constituting clay.
Specific examples thereof include laponite, bentonite, smectite kaolinite, and montmorillonite.

The combination of the two or more thickeners in the present invention is not particularly limited, but from the viewpoint of improving the usability and the skin condition, the natural polysaccharide and / or the cellulosic polymer is used. A combination of two or more selected from among them is preferable, and a combination of one or more natural polysaccharides and one or more cellulosic polymers is more preferable.

Specific examples of preferable combinations are as follows. (I) As a combination of two or more kinds of natural polysaccharides, for example, a combination of at least one selected from sodium alginate, tamarind gum, and carrageenan, a combination of at least one selected from tamarind gum, carrageenan, and xanthan gum, carrageenan. And xanthan gum. (Ii) As a combination of two or more kinds of cellulosic polymers, for example, a combination of at least one selected from cellulose gum, hydroxyethyl cellulose, and hydroxypropylmethylcellulose stearoxy ether, and a combination of hydroxyethyl cellulose and hydroxypropylmethylcellulose stearoxy ether. And so on. (Iii) As a combination of one or more natural polysaccharides and one or more cellulosic polymers, for example, at least one combination selected from sodium alginate, hydroxyethyl cellulose, and hydroxypropylmethyl cellulose stearoxy ether, tamarind gum, and the like. At least one combination selected from cellulose gum, hydroxyethyl cellulose, and hydroxypropylmethyl cellulose stearoxy ether, carrageenan and at least one combination selected from cellulose gum, hydroxyethyl cellulose, and hydroxypropylmethyl cellulose stearoxy ether, xanthan gum. Examples thereof include at least one combination selected from hydroxyethyl cellulose and hydroxypropylmethyl cellulose stearoxy ether.

Among these, a more preferable combination is the combination of (iii) above.

Among the more preferable combinations, the following combinations are mentioned as particularly excellent combinations in terms of individual action and effect while achieving both excellent usability and skin condition improving action. From the viewpoint of increasing the amount of keratin water, the combination of carrageenan and hydroxyethyl cellulose and the combination of xanthan gum and hydroxyethyl cellulose are particularly preferable, and from the viewpoint of ease of mixing, the combination of carrageenan and hydroxypropylmethylcellulose stearoxy ether is particularly preferable, and the foam is fine. From the viewpoint of the above, the combination of carrageenan and cellulose gum is particularly preferable, from the viewpoint of sustaining the feeling of carbonation (crackiness), the combination of carrageenan and cellulose gum is particularly preferable, and from the viewpoint of the moist feeling of the skin, xanthan gum is used. The combination of hydroxypropylmethyl cellulose stearoxy ether, tamarind gum and cellulose gum, carrageenan and hydroxypropylmethyl cellulose stearoxy ether, and carrageenan and hydroxypropylmethylellose stearoxy ether are particularly preferable, and the viewpoint of foam uniformity is particularly preferable. Therefore, a combination of xanthan gum and hydroxyethyl cellulose, a combination of tamarind gum and cellulose gum, a combination of carrageenan and hydroxyethyl cellulose, and a combination of carrageenan and hydroxypropylmethyl cellulose stearoxy ether are particularly preferable.

In addition, since it does not have both an excellent feeling of use and an action of improving skin condition, unfavorable combinations include a combination of sodium alginate, xanthan gum, cellulose gum, hydroxypropylmethyl cellulose, carbomer, polyvinyl alcohol, or bentonite, and xanthan gum. , Cellulose gum, hydroxypropylmethylcellulose, or bentonite, or a combination of cellulose gum and hydroxypropylmethylcellulose, or carbomer.

The content of the thickener in (A), (B), (C), (D), (E), and / or (F) of the present invention is 100% by mass of the total amount of the two agents of the corresponding kit. It is preferably 0.01 part by mass or more and 40 parts by mass or less, and more preferably 0.1 part by mass or more and 30 parts by mass or less. The amount of the thickener in the acid-containing composition and / or the base-containing composition as used herein is the amount of the thickener when one of them contains the thickener, and both of them contain the thickener. If it is contained, it is the total amount thereof, and the amount of the thickener in the acid and base-containing composition and / or the water-containing composition is also the same.

As for the blending ratio of two or more thickeners to be combined, the content of any one of them with respect to 100 parts by mass is preferably 1 part by mass or more and 10000 parts by mass or less, and 5 parts by mass or more and 5000 parts or more. It is more preferably 10 parts by mass or less, and particularly preferably 10 parts by mass or more and 1000 parts by mass or less.

<Water>
As the water that can be used in the present invention, water that can be used in cosmetics, external medicines, quasi-drugs, etc. can be used, but purified water, distilled water, membrane filtered water, ion-exchanged water, etc. are preferable.

The water content in the kits (1) to (3) of the present invention is preferably 20 parts by mass or more and 95 parts by mass or less, preferably 30 parts by mass or less, with respect to 100 parts by mass of the total amount of the two agents of the corresponding kit. It is more preferably more than parts by mass and 90 parts by mass or less.

<Multivalent alcohol>
In the present invention, it is preferable to include a polyhydric alcohol in the external skin preparation from the viewpoint of exhibiting a high moisturizing effect and improving the feeling of use. The polyhydric alcohol is not limited as long as it can be usually used as an external preparation, but for example, polyglycerin such as glycerin, diglycerin, triglycerin, tetraglycerin, ethylene glycol, 1,3-butylene glycol, 1, 4-butylene glycol, propylene glycol, dipropylene glycol, polyethylene glycol, 1,3-propanediol, 1,2-pentanediol, sorbitol, polyglycerin derivative, glucose, fructose, glyceraldehyde, lactose, arabinose, maltose, etc. Examples thereof include sugar alcohols such as reduced sugar, erythritol, martitol, sorbitol, and xylitol, and one or a combination of two or more of these can be used.

The content of the polyhydric alcohol in (A), (B), (C), (D), (E), and / or (F) of the present invention is 100% by mass of the total amount of the two agents of the corresponding kit. It is preferably 1 part by mass or more and 80 parts by mass or less, and more preferably 5 parts by mass or more and 70 parts by mass or less. The amount of polyhydric alcohol referred to here is the amount when one of the kits contains the polyhydric alcohol, and the total amount when both contain the polyhydric alcohol.

<Other ingredients>
The effervescent skin external preparation kit of the present invention includes active ingredients, preservatives, pH adjusters, fats and oils, fragrances, colorants, antioxidants, antibacterial and antifungal agents, alcohols, nonionic surfactants, anionic surfactants, One or more of the components usually used for external skin preparations such as cationic surfactants, surfactants such as amphoteric surfactants, inorganic salts, lubricants, and solvents can be used. Further, in the kit of the present invention, the component to be added can be used for either a solid composition or a water-containing composition, or may be used for either agent.

When other components (components other than water, acidic substances, carbon dioxide generating substances, thickeners, and polyhydric alcohols) are blended in the effervescent skin external preparation kit of the present invention, the total content of the components is 30% by mass or less, particularly 25% by mass or less is preferable from the viewpoint of good foaming and carbon dioxide gas retention.

<Dosage form and amount of ingredients of kit>
The kits (1) to (3) will be described in more detail. In the kits (1) to (3), the dosage form of the solid composition of each kit includes tablets, pellets, granules, fine granules, and powders, but it is mixed with the other agent. Granules, fine granules, and powders are preferable from the viewpoint of ease of use and cost at the time of manufacture.

The dosage form of the water-containing composition of each kit may be gel-like or liquid, but gel-like is preferable from the viewpoint of usability.
The liquid agent has a viscosity at 25 ° C. of preferably less than 3000 mPa · s, more preferably less than 4000 mPa · s. The gel-like agent has a viscosity at 25 ° C. of preferably 5000 Pa · s or more. This viscosity is measured, for example, by a viscometer (RVT type manufactured by Brookfield). The amount of the thickener in the liquid agent is preferably less than 0.05% by mass, more preferably less than 0.01% by mass, and particularly preferably less than 0.005% by mass. On the other hand, the amount of the thickener in the gel-like agent is preferably 0.01% by mass or more, more preferably 0.05% by mass or more.

<Solid composition of the kit of (1) to (3)>
The preferred amounts of the acid and carbon dioxide generating substances in the solid composition of the kits (1) to (3) are as described above. The amount and content of the thickener in these compositions are 0.01% by mass or more and 20% by mass or less, particularly 0.05% by mass or more and 15% by mass in these compositions when the other agent is in the form of a gel. % Or less is preferable from the viewpoint of good foaming and carbon dioxide gas retention, and when the other agent is liquid, 0.01% by mass or more and 30% by mass or less, particularly 0.05. It is preferable that it is 5% by mass or more and 25% by mass or less from the viewpoint of ease of mixing with the liquid agent, foamability, and exhibiting carbon dioxide gas retention.

When the solid composition of the kits (1) to (3) is granulated into granules, the following methods can be mentioned.

When granules are obtained by granulating an acidic substance and / or a carbon dioxide gas generating substance as a mixture with other components, the content of the other components is not particularly limited, but is less than 95% by mass in the above granules. Is preferable. If the other components are present in a content of more than 95% by mass, the foamability is lowered, which is not preferable.
The method for producing the powder or granules is not limited to this embodiment, and includes a dry crushing granulation method, a wet crushing granulation method, a fluidized bed granulation method, a high-speed stirring granulation method, an extrusion granulation method, and the like. Can be manufactured according to the conventional method.

For example, in the production of granules, a matrix base material having a function such as forming granules may be used. When a low melting point compound is used as the matrix base, the carbon dioxide gas generating substance is added to the low melting point compound melted by heating in a container such as a beaker, and the mixture is sufficiently stirred and mixed. Appropriate additives may be added to this as needed. This is further stirred while gradually cooling at room temperature, and left until it hardens. When it hardens to some extent, it may be cooled rapidly in a refrigerator or the like.

Further, for example, the above-mentioned material may be put into a fluidized bed granulator, mixed with an air flow for several minutes, and then sprayed with water to granulate.

When a low melting point compound is not used as the matrix base, the granulating agent is dissolved or dispersed in a suitable solvent such as water or ethanol in a container such as a beaker, and the carbon dioxide gas generating substance is dissolved or dispersed therein. After sufficiently mixing, heat in an oven or the like to remove the solvent and dry. When it is completely solidified, it is crushed, sieved to make the grain size uniform, and then made into granules.

<The water-containing composition of the kits (1) to (3)>
The preferable amounts of the carbon dioxide gas generating substance and the acidic substance in the water-containing composition ((B), (D), (F)) of the kits (1) to (3) are as described above. Further, the proportion of water in the water-containing composition of the kits (1) to (3) is 20% by mass or more, particularly 30% by mass or more, that is, the other agent of each kit ((A), (C), ( E)) is preferable from the viewpoint of mixing property and foamability, and 95% by mass or less, particularly 90% by mass or less is preferable from the viewpoint of improving the feeling of use and improving the skin condition.

When the hydrous composition of the kits (1) to (3) contains a polyhydric alcohol, the proportion of the polyhydric alcohol in the hydrous composition is 1% by mass or more, particularly 10% by mass or more. It is preferable that the content is 80% by mass or less, particularly 70% by mass or less, particularly 60% by mass or less, from the viewpoint of improving the feeling of use and improving the skin condition.

Moisturizers other than polyhydric alcohols, surfactants, pH adjusters, volatile alcohols, oils and fats, fragrances, animal and plant extracts, etc. shall be added to each of the hydrous compositions (1) to (3). Can be done. For example, moisturizers other than polyhydric alcohol include polyoxyalkylene alkyl glucoside, sodium lactate, sodium pyrrolidone carboxylate, almond, avocado, altea, aloe, cheeses, ononis, ginger, licorice, quince seed, clara (kujin), etc. Peppermint, Grapefruit, Cresson, Gentiana, Gentiana lutea, Gobo, Wheat, Saishin, Cactus, Sabonsou, Sanzashi, Jio, Shimotsuke, Ginger, Zeniaoi, Kuwa, Tachijakousou, Winterworm summer grass, Dokudami, Hakka, Hatomugi, Hamameris , Grape, prune, mint, bodaiju, hop, pine, marmelo, marronnier, melissa, yagurumasou, lily, lime, lavender, apple, rice and rice bran, black currant, ibukitranoo, noibara, eleuthero, seaweed and other plant extracts One or more of these can be used.

As the shape of the acidic substance and / or the carbon dioxide gas generating substance, for example, an irregular shape, a flat shape, a polyhedral shape, a spherical shape, a drop shape, a fibrous shape, a columnar shape, a fine powder shape, or the like can be adopted without particular limitation. Further, as the particle size, a wide range can be used without particular limitation. In particular, from the viewpoint of ease of handling and ease of mixing with the viscous composition, those having a particle size distribution of about 1,000 μm or less are more preferable. The particle size distribution in the present invention can be obtained by a normal laser diffraction / scattering method.

In the case of the kit (2), for example, a coat layer may be provided on either or both of the acidic substance and / or the carbon dioxide gas generating substance and other components, or the carbon dioxide gas generating substance may be provided. One or both of the other components may be encapsulated. Further, the acidic substance and / or the carbon dioxide gas generating substance sandwiches and compresses the layer containing the carbon dioxide gas generating substance, the acidic substance and other components between each component or other components so that they do not come into direct contact with each other. It may be molded. As a means for coexisting the acidic substance and / or the carbon dioxide gas generating substance and other components in the same agent, a known method can be mentioned.

The mixing ratio (mass ratio) of the two in the kits (1) to (3) is preferably 1: 0.01 or more and 30 or less for the water-containing composition: solid composition, and 1: 0.05 or more and 20. The following is more preferable.

The amount of each of the acidic substance, carbon dioxide gas generating substance, thickener, and water used in the composition obtained by the skin external preparation kit of the present invention is 0.1 to 15% by mass with respect to the total amount. The carbon dioxide generating substance is preferably 0.1 to 20% by mass, the thickener is preferably 0.1 to 20% by mass, and the water is preferably 40 to 99.6% by mass. When the external preparation for skin contains polyvalent alcohol, the total amount of each of the acidic substances, carbon dioxide gas generating substances, thickeners, water, and polyhydric alcohol used for mixing to obtain the external preparation for skin is the total amount. On the other hand, acidic substances are 0.1 to 10% by mass, carbon dioxide gas generating substances are 0.1 to 10% by mass, thickeners are 0.1 to 15% by mass, water is 30 to 97% by mass, and polyhydric alcohols. Is preferably 0.05 to 50% by mass.

<Use of external skin preparation kit>
The external skin preparation according to the present invention promotes an increase in skin blood flow due to the action of carbon dioxide gas. The external skin preparation of the present invention is excellent in the effect of improving the skin condition such as increasing the water content of the skin, reducing the water evaporation amount, and improving the skin elasticity. In addition, the external skin preparation according to the present invention has a feeling of use (easy to mix, smoothness of foam, fineness of foam, uniform feeling of foam, ease of application, resistance to dripping, elasticity of foam, carbonic acid feeling). And its sustainability, etc.), and also has an excellent feeling of use after use (skin moisturizing, elasticity, brightness, redness, smoothness, smoothness, tightness, etc.). Further, the external skin preparation according to the present invention improves skin quality, rejuvenates the skin, tightens the skin, partially thins the skin, cleanses the skin, prepares the skin, prepares the texture of the skin, keeps the skin healthy, and prevents rough skin. , Tightens the skin, moisturizes the skin, supplements and keeps the moisture and oil content of the skin, keeps the skin soft, protects the skin, prevents the skin from drying out, softens the skin, gives the skin firmness, Not only cosmetics aimed at giving gloss to the skin, smoothing the skin, and making fine wrinkles due to dryness inconspicuous, but also rough skin, rough skin, prevention of rashes, rashes, cracks, cracks, acne, and oil sickness. Skin, prevention of shavings, prevention of sunburn / snow burn, tightening skin, cleansing skin, conditioning skin, keeping skin healthy, moisturizing skin, protecting skin, skin It can be suitably used for any of pharmaceutical products such as non-medicinal products and medicines for the purpose of preventing the skin from drying out. Further, when used on the scalp and hair, the effect of imparting glossiness and smoothness of hair, elasticity to the scalp and moisturizing feeling is enhanced. In addition, the blood flow improving action can be expected to have an action of promoting the proliferation action and hair growth of dermal papilla cells. The external skin preparation according to the present invention is preferably used as cosmetics and quasi-drugs, and is preferably used as cosmetics such as milky lotions, creams, packs and peeling agents, and medicated cosmetics. In particular, it is preferable to use it as a facial mask because it has a good feeling of use and a high skin condition improving effect can be easily obtained.

Hereinafter, the present invention will be described in more detail with reference to examples, but the scope of the present invention is not limited to these examples. In each of the following Examples and Comparative Examples, commercially available raw materials were used unless otherwise specified.

<Manufacturing of effervescent skin external preparation>
Each component shown in Tables 1 to 3 was blended and mixed in the composition shown in the same table to produce a skin external preparation kit of each Example and Comparative Example. In Tables 1 to 3, an acidic substance is also simply referred to as an "acid", and a carbon dioxide generating substance is also simply referred to as a "carbonate".

The following [Evaluation 1] was performed on the above-mentioned Examples and Comparative Examples.
[Evaluation 1]
Two healthy women in their twenties and thirties were randomly selected as subjects. The inside of each subject's forearm was washed with a cleanser and allowed to rest for 15 minutes in the measurement room. Next, the amount of water evaporation, the amount of water in the stratum corneum, and the elasticity were measured by the following methods for the measured portion of 4 cm × 4 cm where the effervescent skin external agent was to be applied. Next, the effervescent skin external preparation was applied to the measurement site and allowed to stand for 10 minutes. Then, the effervescent external skin preparation was removed and washed with water. The same measurement was performed after 15 minutes had passed after washing and after using the effervescent skin external preparation. The subject spent a rest in the measurement room during the measurement.
The skin condition measurement results after use are shown in FIGS. 1 to 3. The values in FIGS. 1 to 3 are relative values (rate of change) when the measured value before application of the effervescent skin external preparation is 1. The smaller the value of water evaporation, the better the barrier function, and the larger the value, the better the water content of the stratum corneum, and the larger the value, the better the elasticity.

The skin condition before and after application of the effervescent skin external preparation was measured using the following devices. In addition, these measurements were performed by the standard method described in the instructions that accompany the instrument.
-Moisture evaporation: Measured using a Tevameter (registered trademark) TM300 (CK).
-Moisture content of the stratum corneum: Measured with the skin surface stratum corneum moisture content measuring device SKION-200EX (manufactured by IBS Co., Ltd.). This skin surface stratum corneum water content measuring device evaluates the conductance (electrical conductivity, unit: μS) of the skin as the water content of the stratum corneum.
-Elasticity: Measured with a skin viscosity elasticity measuring device Cutometer MPA580 (manufactured by Course + Khazaka).

As shown in FIGS. 1 to 3, the effervescent skin external preparations of each example in which two or more specific thickeners are blended in combination are comparative examples in which the combination of these thickeners is not blended. Compared with the effervescent external skin preparation, the increase in water content and elasticity of the stratum corneum was large, and the decrease in water evaporation was small. Further, as is clear from Examples 1 to 3, the kits having any of the configurations (1) to (3) showed a high skin condition improving effect. Therefore, it is clear that the effervescent skin external preparation of the present invention, which is a combination of two or more specific thickeners, has a high skin condition improving effect.

The following [Evaluation 2] was performed on the above-mentioned Examples and Comparative Examples.
[Evaluation 2]
Two healthy women in their twenties and thirties were randomly selected as subjects. The inside of each subject's forearm was washed with a cleanser and allowed to rest for 15 minutes in the measurement room. Next, the above-mentioned effervescent skin external preparation was applied to the measurement site and allowed to stand for 10 minutes. Next, the effervescent skin external preparation was removed and washed with water. The evaluation items (16 items) at the time of use and after use were evaluated based on the evaluation criteria of 7 stages. The evaluation criteria are shown in Table A below, and the results are shown in Tables B to D below. The following results are the average values of the evaluation points of the two subjects.

As shown in Tables B to D, the effervescent skin external preparation of each example containing a combination of two or more specific thickeners is compared with the effervescent skin external preparation of each comparative example not containing this. , Excellent usability during use (easy to mix, smoothness of foam, fineness of foam, uniform feeling of foam, ease of application, difficulty in dripping, elasticity of foam, carbonic feeling and its duration), and after use It was excellent in usability (moist feeling, elasticity, brightness, redness, smoothness, smoothness, tightness) of the skin. Further, as is clear from Examples 1 to 3, the kits having any of the configurations (1) to (3) were excellent in usability.

Therefore, it is clear that the effervescent skin external preparation of the present invention, which is a combination of two or more specific thickeners, has an excellent skin condition improving effect and a feeling of use.

Claims (3)

A kit for obtaining an acidic substance, a carbon dioxide gas generating substance that reacts with the acidic substance to generate carbon dioxide gas, two or more kinds of thickeners, and an effervescent skin external preparation obtained by mixing water. The thickener is a combination of two or more selected from sodium alginate, sodium polyacrylate, (Acrylate / alkyl acrylate (C10-30)) crosspolymer and (acryloyldimethyltaurine ammonium / VP) copolymer, polyacrylic acid. Selected from Na, (Acrylate / Alkyl Acrylate (C10-30)) Cross Polymer and (Acryloyldimethyltaurine Ammonium / VP) Copolymer, and Tamarind Gum, Carrageenan, Xanthan Gum, Sodium Carboxymethyl Cellulose, Hydroxyethyl Cellulose and Carbomer. One or more combinations, or one or more combinations selected from sodium alginate, tamarind gum, carrageenan, and hydroxyethyl cellulose, and a kit (1) having any of the following configurations (1) to (3). ) Solid composition containing an acidic substance (A) and a composition containing water, a thickener, and a carbon dioxide gas generating substance (B) (2) A solid composition containing an acidic substance and a carbon dioxide gas generating substance (C) And a composition (D) containing water and a thickener (3) a solid composition (E) containing a carbon dioxide gas generating substance and a composition (F) containing water, a thickener and an acidic substance (however, Except for the following combinations of the thickeners (B), (D), and (F): Sodium alginate and xanthan gum, cellulose gum, hydroxypropylmethyl cellulose, carbomer, polyvinyl alcohol, or bentonite combination, xanthan gum. And a combination of cellulose gum, hydroxypropylmethylcellulose, or bentonite, or a combination of cellulose gum and hydroxypropylmethylcellulose, or carbomer). The kit according to claim 1, wherein one or both of the compositions constituting the kit further contains a polyhydric alcohol. The solid composition ((A), (C), (E)) is in the form of powder, and the composition containing water and a thickener ((B), (D), (F)) is in the form of a gel. The kit for obtaining the effervescent skin external preparation according to claim 1 or 2, characterized in that it is present.

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