JP7057750B6 - 温熱増感放射線療法のための適応治療計画 - Google Patents
温熱増感放射線療法のための適応治療計画 Download PDFInfo
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- JP7057750B6 JP7057750B6 JP2018521576A JP2018521576A JP7057750B6 JP 7057750 B6 JP7057750 B6 JP 7057750B6 JP 2018521576 A JP2018521576 A JP 2018521576A JP 2018521576 A JP2018521576 A JP 2018521576A JP 7057750 B6 JP7057750 B6 JP 7057750B6
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- heat
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- 238000001959 radiotherapy Methods 0.000 title claims description 195
- 206010020843 Hyperthermia Diseases 0.000 title claims description 151
- 238000011282 treatment Methods 0.000 title claims description 15
- 230000036031 hyperthermia Effects 0.000 claims description 124
- 238000012384 transportation and delivery Methods 0.000 claims description 73
- 230000005855 radiation Effects 0.000 claims description 40
- 238000000015 thermotherapy Methods 0.000 claims description 27
- 206010070834 Sensitisation Diseases 0.000 claims description 20
- 238000000034 method Methods 0.000 claims description 20
- 230000008313 sensitization Effects 0.000 claims description 20
- 238000012544 monitoring process Methods 0.000 claims description 15
- 206010037660 Pyrexia Diseases 0.000 claims description 14
- 230000033001 locomotion Effects 0.000 claims description 5
- 230000004044 response Effects 0.000 claims 1
- 230000003044 adaptive effect Effects 0.000 description 29
- 238000010438 heat treatment Methods 0.000 description 14
- 230000001225 therapeutic effect Effects 0.000 description 7
- 238000013459 approach Methods 0.000 description 5
- 230000004071 biological effect Effects 0.000 description 5
- 238000011404 fractionated radiotherapy Methods 0.000 description 5
- 238000003384 imaging method Methods 0.000 description 4
- 238000002604 ultrasonography Methods 0.000 description 4
- 238000009529 body temperature measurement Methods 0.000 description 3
- 238000004364 calculation method Methods 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000002595 magnetic resonance imaging Methods 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 230000000451 tissue damage Effects 0.000 description 2
- 231100000827 tissue damage Toxicity 0.000 description 2
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010057040 Temperature intolerance Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000008543 heat sensitivity Effects 0.000 description 1
- 238000009217 hyperthermia therapy Methods 0.000 description 1
- 230000005865 ionizing radiation Effects 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000013421 nuclear magnetic resonance imaging Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
Images
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/103—Treatment planning systems
- A61N5/1031—Treatment planning systems using a specific method of dose optimization
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/103—Treatment planning systems
- A61N5/1037—Treatment planning systems taking into account the movement of the target, e.g. 4D-image based planning
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/103—Treatment planning systems
- A61N5/1038—Treatment planning systems taking into account previously administered plans applied to the same patient, i.e. adaptive radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/103—Treatment planning systems
- A61N5/1039—Treatment planning systems using functional images, e.g. PET or MRI
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1075—Monitoring, verifying, controlling systems and methods for testing, calibrating, or quality assurance of the radiation treatment apparatus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N7/02—Localised ultrasound hyperthermia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0089—Chemotherapy developing heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0095—Heating or cooling appliances for medical or therapeutic treatment of the human body with a temperature indicator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0626—Monitoring, verifying, controlling systems and methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0626—Monitoring, verifying, controlling systems and methods
- A61N2005/0627—Dose monitoring systems and methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
- A61N2005/1087—Ions; Protons
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Pathology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Radiation-Therapy Devices (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562248484P | 2015-10-30 | 2015-10-30 | |
| US62/248,484 | 2015-10-30 | ||
| PCT/EP2016/074609 WO2017071965A1 (en) | 2015-10-30 | 2016-10-13 | Adaptive treatment planning for hyperthermia-enhanced radiation therapy |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2018531728A JP2018531728A (ja) | 2018-11-01 |
| JP2018531728A5 JP2018531728A5 (enExample) | 2019-11-14 |
| JP7057750B2 JP7057750B2 (ja) | 2022-04-20 |
| JP7057750B6 true JP7057750B6 (ja) | 2022-06-02 |
Family
ID=57133208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018521576A Active JP7057750B6 (ja) | 2015-10-30 | 2016-10-13 | 温熱増感放射線療法のための適応治療計画 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10898728B2 (enExample) |
| EP (1) | EP3368155B1 (enExample) |
| JP (1) | JP7057750B6 (enExample) |
| CN (1) | CN108348770B (enExample) |
| WO (1) | WO2017071965A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3454737B1 (en) | 2016-03-31 | 2021-07-14 | Thomas Jefferson University | Tumor bed implant for multimodality treatment of at risk tissue surrounding a resection cavity |
| EP4082609B1 (en) * | 2021-04-27 | 2024-12-18 | RaySearch Laboratories AB | Optimization of thermoradiotherapy treatment |
| EP4112123A1 (en) * | 2021-07-02 | 2023-01-04 | RaySearch Laboratories AB | Planning and optimization of multimodality therapy |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040243200A1 (en) | 2003-06-02 | 2004-12-02 | Turner Paul F. | Invasive microwave antenna array for hyperthermia and brachytherapy |
| JP2012504977A (ja) | 2008-10-08 | 2012-03-01 | ヘルムホルツ・ツェントルム・ミュンヒェン・ドイチェス・フォルシュンクスツェントルム・フューア・ゲズントハイト・ウント・ウムベルト(ゲーエムベーハー) | 放射線療法及び温熱療法を組み合わせた治療装置 |
| US20130131433A1 (en) | 2010-01-12 | 2013-05-23 | Koninklijke Philips Electronics N.V. | Therapeutic apparatus |
| WO2014096993A1 (en) | 2012-12-17 | 2014-06-26 | Koninklijke Philips N.V. | Real-time adaptive dose computation radiation therapy |
| WO2015067786A1 (en) | 2013-11-08 | 2015-05-14 | Koninklijke Philips N.V. | Medical apparatus for radiotherapy and ultrasound heating |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9320813B2 (en) * | 2002-02-14 | 2016-04-26 | Gholam A. Peyman | Method and composition for hyperthermally treating cells |
| WO2005107601A2 (en) | 2004-05-06 | 2005-11-17 | Focus Surgery, Inc. | Method and apparatus for the selective treatment of tissue |
| WO2007015179A1 (en) | 2005-08-03 | 2007-02-08 | Koninklijke Philips Electronics, N.V. | Ultrasound monitoring and feedback for magnetic hyperthermia |
| US8016757B2 (en) * | 2005-09-30 | 2011-09-13 | University Of Washington | Non-invasive temperature estimation technique for HIFU therapy monitoring using backscattered ultrasound |
| US8222616B2 (en) | 2007-10-25 | 2012-07-17 | Tomotherapy Incorporated | Method for adapting fractionation of a radiation therapy dose |
| WO2010051322A1 (en) * | 2008-10-28 | 2010-05-06 | University Of Toledo | System for concurrent delivery of thermobrachytherapy in the treatment of cancers |
| US8328726B2 (en) * | 2009-04-01 | 2012-12-11 | Tomy Varghese | Method and apparatus for monitoring tissue ablation |
| JP5771226B2 (ja) | 2010-03-08 | 2015-08-26 | コーニンクレッカ フィリップス エヌ ヴェ | 効率的な線量計算を含む線量計算タスクのスケジューリング |
| CN103260701B (zh) | 2010-12-16 | 2017-10-31 | 皇家飞利浦电子股份有限公司 | 采用大腔膛的核及磁共振成像或者大腔膛的ct及磁共振成像的辐射治疗规划和跟踪系统 |
| AU2012224923B2 (en) | 2011-03-10 | 2014-12-04 | Magforce Ag | Computer-aided simulation tool for providing assistance in the planning of thermotherapy |
| RU2014139011A (ru) | 2012-02-27 | 2016-04-20 | Конинклейке Филипс Н.В. | Система и/или способ компьютерной томографии (ст) - высокоинтенсивного фокусированного ультразвука (hifu) |
| WO2013164746A1 (en) | 2012-05-02 | 2013-11-07 | Koninklijke Philips N.V. | Imaging thermometry |
| WO2015085252A1 (en) | 2013-12-06 | 2015-06-11 | Sonitrack Systems, Inc. | Radiotherapy dose assessment and adaptation using online imaging |
-
2016
- 2016-10-13 WO PCT/EP2016/074609 patent/WO2017071965A1/en not_active Ceased
- 2016-10-13 JP JP2018521576A patent/JP7057750B6/ja active Active
- 2016-10-13 CN CN201680063376.4A patent/CN108348770B/zh active Active
- 2016-10-13 EP EP16781445.8A patent/EP3368155B1/en active Active
- 2016-10-13 US US15/769,078 patent/US10898728B2/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040243200A1 (en) | 2003-06-02 | 2004-12-02 | Turner Paul F. | Invasive microwave antenna array for hyperthermia and brachytherapy |
| JP2012504977A (ja) | 2008-10-08 | 2012-03-01 | ヘルムホルツ・ツェントルム・ミュンヒェン・ドイチェス・フォルシュンクスツェントルム・フューア・ゲズントハイト・ウント・ウムベルト(ゲーエムベーハー) | 放射線療法及び温熱療法を組み合わせた治療装置 |
| US20130131433A1 (en) | 2010-01-12 | 2013-05-23 | Koninklijke Philips Electronics N.V. | Therapeutic apparatus |
| WO2014096993A1 (en) | 2012-12-17 | 2014-06-26 | Koninklijke Philips N.V. | Real-time adaptive dose computation radiation therapy |
| WO2015067786A1 (en) | 2013-11-08 | 2015-05-14 | Koninklijke Philips N.V. | Medical apparatus for radiotherapy and ultrasound heating |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108348770A (zh) | 2018-07-31 |
| US20180304100A1 (en) | 2018-10-25 |
| WO2017071965A1 (en) | 2017-05-04 |
| US10898728B2 (en) | 2021-01-26 |
| JP2018531728A (ja) | 2018-11-01 |
| CN108348770B (zh) | 2020-09-25 |
| EP3368155A1 (en) | 2018-09-05 |
| EP3368155B1 (en) | 2019-09-25 |
| JP7057750B2 (ja) | 2022-04-20 |
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