JP7036594B2 - Braf陽性癌を患っている患者を、braf阻害剤に対する非レスポンダーであると及びmapk/erk阻害剤に対するレスポンダーであると同定する手段及び方法 - Google Patents
Braf陽性癌を患っている患者を、braf阻害剤に対する非レスポンダーであると及びmapk/erk阻害剤に対するレスポンダーであると同定する手段及び方法 Download PDFInfo
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| WO2018213302A1 (en) * | 2017-05-16 | 2018-11-22 | Biomed Valley Discoveries, Inc. | Compositions and methods for treating cancer with atypical braf mutations |
| CN112795647B (zh) * | 2019-11-14 | 2022-08-16 | 北京肿瘤医院(北京大学肿瘤医院) | 一种肿瘤标志物及其应用 |
| CN111020033A (zh) * | 2019-12-24 | 2020-04-17 | 中山大学达安基因股份有限公司 | 多重检测braf基因突变的试剂盒及方法 |
| EP4359781A4 (en) * | 2021-06-23 | 2025-05-14 | Royal Melbourne Institute of Technology | CONDUCTOMETRIC SENSOR FOR DETECTING A NUCLEIC ACID AND ITS DETECTION METHOD |
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| WO2012068562A2 (en) | 2010-11-19 | 2012-05-24 | The Regents Of The University Of California | Compositions and methods for detection and treatment of b-raf inhibitor-resistant melanomas |
| JP2013543008A (ja) | 2010-11-19 | 2013-11-28 | グラクソスミスクライン、インテレクチュアル、プロパティー、ナンバー2、リミテッド | Braf阻害剤による治療方法 |
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| US20120252015A1 (en) * | 2011-02-18 | 2012-10-04 | Bio-Rad Laboratories | Methods and compositions for detecting genetic material |
| CN103911428B (zh) * | 2009-03-27 | 2016-02-24 | 生命技术公司 | 用于检测等位基因变体的方法、组合物和试剂盒 |
| US20130315934A1 (en) * | 2010-10-28 | 2013-11-28 | Yale University | Methods and Compositions for Assessing and Treating Cancer |
| WO2012061683A2 (en) | 2010-11-05 | 2012-05-10 | Glaxosmithkline Llc | Methods for treating cancer |
| WO2014009318A1 (en) * | 2012-07-11 | 2014-01-16 | Boehringer Ingelheim International Gmbh | 3-{3-[1 -(4-dimethylaminomethyl-phenylamino)-1 -phenyl-meth-(z)-ylidene]-2-oxo-2,3-dihydro-1 h-indol-6-yll-propynoic acid ethylamide and its use in the treatment of cancer |
| WO2014009319A1 (en) * | 2012-07-11 | 2014-01-16 | Boehringer Ingelheim International Gmbh | Indolinone derivatives anticancer compounds |
| WO2014052613A2 (en) | 2012-09-26 | 2014-04-03 | Insight Genetics, Inc. | Methods and compositions relating to next generation sequencing for genetic testing in alk related cancers |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2012068562A2 (en) | 2010-11-19 | 2012-05-24 | The Regents Of The University Of California | Compositions and methods for detection and treatment of b-raf inhibitor-resistant melanomas |
| JP2013543008A (ja) | 2010-11-19 | 2013-11-28 | グラクソスミスクライン、インテレクチュアル、プロパティー、ナンバー2、リミテッド | Braf阻害剤による治療方法 |
Non-Patent Citations (4)
| Title |
|---|
| Cancer Res.,2003年,Vol.63,No.15,pp.4561-4567 |
| J.Mol.Diagn.,2013年,Vol.15,No.1,pp.94-100 |
| MOLECULAR CANCER THERAPEUTICS,2012年4月1日,Vol.11,No.4,pp.909-920 |
| Nature,2010年,Vol.468,No.7326,pp.973-977 |
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| WO2016008853A1 (en) | 2016-01-21 |
| CA2953732A1 (en) | 2016-01-21 |
| JP2017529094A (ja) | 2017-10-05 |
| EP3169797A1 (en) | 2017-05-24 |
| EP3169797B2 (en) | 2025-02-19 |
| ES2751925T5 (en) | 2025-05-13 |
| ES2751925T3 (es) | 2020-04-02 |
| US20190194757A1 (en) | 2019-06-27 |
| EP3169797B1 (en) | 2019-08-21 |
| CA2953732C (en) | 2023-09-26 |
| CN107148481A (zh) | 2017-09-08 |
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