JP7000153B2 - 長時間作用性ctp修飾成長ホルモンポリペプチドを生成する方法 - Google Patents

長時間作用性ctp修飾成長ホルモンポリペプチドを生成する方法 Download PDF

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Publication number
JP7000153B2
JP7000153B2 JP2017531763A JP2017531763A JP7000153B2 JP 7000153 B2 JP7000153 B2 JP 7000153B2 JP 2017531763 A JP2017531763 A JP 2017531763A JP 2017531763 A JP2017531763 A JP 2017531763A JP 7000153 B2 JP7000153 B2 JP 7000153B2
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Prior art keywords
ctp
another embodiment
hgh
modified
modified hgh
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JP2017531763A
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Japanese (ja)
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JP2018508465A (ja
Inventor
ハーショービッツ、オーレン
モスクコビッチ、ラウラ
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Prolor Biotech Inc
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Modigene Inc
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Priority claimed from PCT/IL2015/051196 external-priority patent/WO2016092549A1/en
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormones [GH] (Somatotropin)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/59Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/31Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
JP2017531763A 2014-12-10 2015-12-10 長時間作用性ctp修飾成長ホルモンポリペプチドを生成する方法 Active JP7000153B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462090104P 2014-12-10 2014-12-10
US62/090,104 2014-12-10
PCT/IL2015/051196 WO2016092549A1 (en) 2014-12-10 2015-12-10 Methods of producing long acting ctp-modified growth hormone polypeptides

Related Child Applications (1)

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JP2020043284A Division JP7042859B2 (ja) 2014-12-10 2020-03-12 長時間作用性ctp修飾成長ホルモンポリペプチドを生成する方法

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JP2018508465A JP2018508465A (ja) 2018-03-29
JP7000153B2 true JP7000153B2 (ja) 2022-01-19

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JP2017531763A Active JP7000153B2 (ja) 2014-12-10 2015-12-10 長時間作用性ctp修飾成長ホルモンポリペプチドを生成する方法
JP2020043284A Active JP7042859B2 (ja) 2014-12-10 2020-03-12 長時間作用性ctp修飾成長ホルモンポリペプチドを生成する方法
JP2022040089A Active JP7437865B2 (ja) 2014-12-10 2022-03-15 高度にグリコシル化されたヒト絨毛性ゴナドトロピンカルボキシ末端ペプチド(CTP)修飾ヒト成長ホルモン(hGH)ポリペプチドを含む、精製された医薬組成物

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JP2020043284A Active JP7042859B2 (ja) 2014-12-10 2020-03-12 長時間作用性ctp修飾成長ホルモンポリペプチドを生成する方法
JP2022040089A Active JP7437865B2 (ja) 2014-12-10 2022-03-15 高度にグリコシル化されたヒト絨毛性ゴナドトロピンカルボキシ末端ペプチド(CTP)修飾ヒト成長ホルモン(hGH)ポリペプチドを含む、精製された医薬組成物

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JP (3) JP7000153B2 (es)
AR (1) AR102969A1 (es)
CA (1) CA2914916A1 (es)
MY (1) MY184625A (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7000153B2 (ja) * 2014-12-10 2022-01-19 オプコ バイオロジクス リミテッド 長時間作用性ctp修飾成長ホルモンポリペプチドを生成する方法
KR101926658B1 (ko) 2017-03-15 2018-12-07 이인철 반도체 챔버용 펌프 시스템

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013018098A2 (en) 2011-08-02 2013-02-07 Prolor Biotech Ltd. Long-acting growth hormone and methods of producing same
WO2014080401A2 (en) 2012-11-20 2014-05-30 Prolor Biotech Inc Method of increasing the hydrodynamic volume of polypeptides by attaching to gonadotrophin carboxy terminal peptides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7553941B2 (en) * 2006-02-03 2009-06-30 Modigene Inc Long-acting polypeptides and methods of producing same
JP7000153B2 (ja) * 2014-12-10 2022-01-19 オプコ バイオロジクス リミテッド 長時間作用性ctp修飾成長ホルモンポリペプチドを生成する方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013018098A2 (en) 2011-08-02 2013-02-07 Prolor Biotech Ltd. Long-acting growth hormone and methods of producing same
WO2014080401A2 (en) 2012-11-20 2014-05-30 Prolor Biotech Inc Method of increasing the hydrodynamic volume of polypeptides by attaching to gonadotrophin carboxy terminal peptides

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ファルマシア(2014)Vol.50,No.8,p.746-750

Also Published As

Publication number Publication date
JP2018508465A (ja) 2018-03-29
AR102969A1 (es) 2017-04-05
JP7042859B2 (ja) 2022-03-28
MY184625A (en) 2021-04-09
JP2020110162A (ja) 2020-07-27
JP7437865B2 (ja) 2024-02-26
JP2022078300A (ja) 2022-05-24
CA2914916A1 (en) 2016-06-10

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