JP6977957B2 - 被覆粒子を製造する方法 - Google Patents

被覆粒子を製造する方法 Download PDF

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Publication number
JP6977957B2
JP6977957B2 JP2019541420A JP2019541420A JP6977957B2 JP 6977957 B2 JP6977957 B2 JP 6977957B2 JP 2019541420 A JP2019541420 A JP 2019541420A JP 2019541420 A JP2019541420 A JP 2019541420A JP 6977957 B2 JP6977957 B2 JP 6977957B2
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core
coated particles
weight
total weight
present
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JP2019541420A
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English (en)
Japanese (ja)
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JP2020508291A (ja
JP2020508291A5 (enExample
Inventor
ジハーン アクカール，
エルガー フンダ，
ロニ シュヴァイケルト，
カイ アーバン，
オリヴィア， ブリジット ヴィドーニ，
アーンスト ツェディ，
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DSM IP Assets BV
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DSM IP Assets BV
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Publication of JP2020508291A5 publication Critical patent/JP2020508291A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glanulating (AREA)
JP2019541420A 2017-02-20 2018-02-16 被覆粒子を製造する方法 Active JP6977957B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17156871.0 2017-02-20
EP17156871 2017-02-20
PCT/EP2018/053855 WO2018149952A1 (en) 2017-02-20 2018-02-16 Process for producing coated particles

Publications (3)

Publication Number Publication Date
JP2020508291A JP2020508291A (ja) 2020-03-19
JP2020508291A5 JP2020508291A5 (enExample) 2020-12-10
JP6977957B2 true JP6977957B2 (ja) 2021-12-08

Family

ID=58185260

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019541420A Active JP6977957B2 (ja) 2017-02-20 2018-02-16 被覆粒子を製造する方法

Country Status (8)

Country Link
US (1) US10966934B2 (enExample)
EP (1) EP3582758A1 (enExample)
JP (1) JP6977957B2 (enExample)
KR (1) KR102515641B1 (enExample)
CN (1) CN110325177A (enExample)
AU (1) AU2018222638B2 (enExample)
NZ (1) NZ755788A (enExample)
WO (1) WO2018149952A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4440341A1 (en) 2021-11-29 2024-10-09 Chr. Hansen A/S Fat and wax microencapsulated ambient stable bacteria and probiotics

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4828857A (en) * 1984-10-05 1989-05-09 Warner-Lambert Company Novel sweetener delivery systems
US5059416A (en) * 1989-06-26 1991-10-22 Warner-Lambert Company Zinc compound delivery system with improved taste and texture
US5200236A (en) * 1989-11-15 1993-04-06 Lever Brothers Company, Division Of Conopco, Inc. Method for wax encapsulating particles
US5230822A (en) * 1989-11-15 1993-07-27 Lever Brothers Company, Division Of Conopco, Inc. Wax-encapsulated particles
US5258132A (en) * 1989-11-15 1993-11-02 Lever Brothers Company, Division Of Conopco, Inc. Wax-encapsulated particles
JP3313114B2 (ja) * 1992-06-16 2002-08-12 不二製油株式会社 乳化剤及び乳化組成物並びに粉末化組成物
US5733575A (en) * 1994-10-07 1998-03-31 Bpsi Holdings, Inc. Enteric film coating compositions, method of coating therewith, and coated forms
US5891476A (en) * 1997-12-22 1999-04-06 Reo; Joe P. Tastemasked pharmaceutical system
US6025315A (en) * 1999-03-25 2000-02-15 Colgate Palmolive Company Automatic dishwashing tablets
EP1066836A1 (en) * 1999-06-11 2001-01-10 Sensus, part of Coöperatie COSUN U.A. Filler/binder hollow particles for tablets
US20040043070A1 (en) * 2002-05-14 2004-03-04 Ayres James W. Hot melt coating by direct blending and coated substrates
FR2851734B1 (fr) * 2003-02-28 2006-06-09 Galenix Innovations Procede pour la fabrication d'une composition pharmaceutique sous la forme de comprimes contenant un fibrate et comprimes obtenus selon le procede
US20080085318A1 (en) * 2005-07-16 2008-04-10 Cherukuri S R Coated compositions and methods for preparing same
ES2732833T3 (es) * 2009-03-26 2019-11-26 Advanced Bionutrition Corp Microencapsulación de sustancias bioactivas y métodos de obtención de la misma
MX351421B (es) * 2011-10-14 2017-10-13 Dsm Ip Assets Bv Nuevo sistema de recubrimiento.
CN108135858B (zh) * 2015-10-02 2022-03-22 帝斯曼知识产权资产管理有限公司 生产压制片剂的方法

Also Published As

Publication number Publication date
EP3582758A1 (en) 2019-12-25
AU2018222638A1 (en) 2019-08-15
JP2020508291A (ja) 2020-03-19
US20190380971A1 (en) 2019-12-19
CN110325177A (zh) 2019-10-11
WO2018149952A1 (en) 2018-08-23
KR20190117520A (ko) 2019-10-16
KR102515641B1 (ko) 2023-03-30
US10966934B2 (en) 2021-04-06
AU2018222638B2 (en) 2023-03-16
NZ755788A (en) 2022-05-27
BR112019017073A2 (pt) 2020-04-07

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