JP6956146B2 - Toothpaste composition - Google Patents

Description

The present invention relates to a dentifrice composition.

In addition to tartar and plaque, human teeth are colored by the adhesion of various colored substances to the surface, and the gloss is also reduced. Phytic acid is known to have an effect of removing tartar from tobacco and an effect of suppressing tartar adhesion, and it prevents such deterioration of coloring and gloss and gives an excellent whitening effect to teeth, and thus is used for various oral cavity. It is used in the composition.

On the other hand, depending on its content, phytic acid tends to strongly bring about a "convergent feeling" that makes the gums tighten, or a "squeaky feeling" that makes the teeth and gums rub against each other unnecessarily. Attempts have also been made to treat this as an unnecessary feel and suppress it. For example, in Patent Document 1, an excellent whitening effect is obtained by containing phytic acid and monofluorophosphate under a specific quantitative relationship and limiting the content of a fluorine ion supply compound, polyphosphoric acid or a salt thereof. While ensuring the above, we are trying to suppress such a squeaky feeling.

On the other hand, the astringent feeling that can be brought about by phytic acid has been developed with the consideration that it should not necessarily be excluded from the balance with the compatibility of other components. For example, in Patent Documents 2 and 3, xanthan gum and sodium carboxymethyl cellulose are used in a specific mass ratio together with phytic acid and the like while adjusting the pH environment, so that the liquid has a feeling of convergence derived from phytic acid and the like. A dentifrice composition with reduced separation and spinnability is disclosed.

International Publication No. 2015/190402 Japanese Unexamined Patent Publication No. 2011-51955 Japanese Unexamined Patent Publication No. 2014-37444

However, if the suppression of the convergent feeling and the squeaky feeling is continued as in the composition described in Patent Document 1, it may become a factor that the refreshing and comfortable feeling after washing is also suppressed. On the contrary, even if the astringent feeling and the squeaky feeling are maintained as in the compositions described in Patent Documents 2 to 3, in the oral cavity rich in sensory nerves, it is perceived as a discomfort different from that in the normal oral cavity. There is a risk that it will end up.
Under these circumstances, the feeling of convergence and squeakyness derived from phytic acid disappears while giving a feeling of comfort after having a feeling of convergence if it disappears promptly after being brought about when applied into the oral cavity. Therefore, it was unexpectedly found by the present inventor that it is perceived as a refreshing and comfortable "cleaning feeling" after washing.

Therefore, the present invention appropriately shortens the onset time of phytic acid-derived astringent sensation and squeaky sensation, and after having a convergent sensation and squeaky sensation, quickly disappears while providing a comfortable sensation, thereby realizing a comfortable sensation. With respect to a toothpaste composition that can provide an excellent cleansing sensation.

Therefore, as a result of various studies, the present inventor has found that phytic acid or a salt thereof is contained in a specific amount, and a nonionic surfactant, silicic anhydride and polyethylene glycol are contained in specific mass ratios, thereby being derived from phytic acid. It has been found that a toothpaste composition can be obtained in which the astringent and squeaky feelings of the above appear immediately in the oral cavity and then disappear rapidly. That is, the present inventor can perceive a feeling of convergence and a squeaky feeling from the time when it is applied into the oral cavity to the time when water is contained in the oral cavity and squeaks. We have realized a toothpaste composition that eliminates the squeaky feeling and allows you to feel an excellent cleaning feeling.

Therefore, in the present invention, the following components (A) to (D):
(A) Phytic acid or its salt acid equivalent amount of 0.01% by mass or more and 1.0% by mass or less (B) Nonionic surfactant (C) Silica anhydride (D) Polyethylene glycol is contained.
The mass ratio ((B) / {(A) + (C)}) of the content of the component (B) to the total of the acid conversion amount of the component (A) and the content of the component (C) is 0.03 or more. It provides a dentifrice composition of 0.3 or less.

According to the dentifrice composition of the present invention, the suppression of the astringent sensation and the squeaky sensation derived from phytic acid or a salt thereof is not unnecessarily prolonged and is not sustained more than necessary, and a comfortable sensation when applied into the oral cavity. Since it disappears quickly after being perceived as, you can feel a refreshing and comfortable "cleansing feeling" after washing.

Hereinafter, the present invention will be described in detail.
In the present specification, the "cleansing feeling" refers to the feeling that has been conventionally referred to as the astringent feeling or squeaky feeling derived from phytic acid or a salt thereof when the dentifrice composition of the present invention is applied into the oral cavity. Since it is immediately perceived in the oral cavity and then disappears rapidly, it means a feeling in the oral cavity where a refreshing and comfortable feeling after washing spreads and it can be recognized that the washing has been performed well.
Therefore, with the dentifrice composition of the present invention, the astringent feeling and squeaky feeling brought about when applied into the oral cavity are immediately perceived in the oral cavity and then quickly disappear, so that an excellent "cleansing feeling" is obtained. You can feel it.

The toothpaste composition of the present invention contains phytic acid or a salt thereof as the component (A) in an amount of 0.01% by mass or more and 1.0% by mass or less. Phytic acid or a salt thereof effectively removes minute stains or solid products adhering to or accumulating on the tooth surface to exert an excellent whitening effect on teeth and enhance the gloss-imparting effect. Can be done. Phytic acid, also known as myo-inositol hexaphosphate, is an inositol phosphate ester compound.
Examples of the salt include alkali metal salts such as sodium and potassium, ammonium salts and the like, and one or more selected from these are preferable, and alkali metal salts are preferable.

The content of the component (A) is 0. It is 01% by mass or more, preferably 0.05% by mass or more, and more preferably 0.1% by mass or more. The content of the component (A) is 1. It is 0% by mass or less, preferably 0.8% by mass or less, and more preferably 0.7% by mass or less. The content of the component (A) in the toothpaste composition of the present invention is 0.01% by mass or more and 1% by mass or less, preferably 0.05 to 0.8% by mass, in terms of acid. Yes, more preferably 0.1 to 0.7% by mass.
The "content of the component (A)" is the value of the "acid conversion amount" as described above, regardless of the type of salt form thereof.

The dentifrice composition of the present invention contains a nonionic surfactant as a component (B). By containing such a component (B), the previously recognized astringent feeling and squeaky feeling derived from the component (A) are quickly extinguished after the toothpaste composition of the present invention is applied into the oral cavity, and a comfortable astringent feeling is obtained. You can feel it as a squeaky feeling.

Specific examples of the component (B) include polyoxyethylene sorbitan fatty acid ester, polyoxyethylene hydrogenated castor oil, polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyglycerin fatty acid ester, and sucrose fatty acid ester. One kind or two or more kinds selected from are mentioned. Among them, one or more selected from polyoxyethylene sorbitan fatty acid ester, polyoxyethylene hydrogenated castor oil, and polyoxyethylene alkyl ether are preferable, and polyoxyethylene sorbitan fatty acid ester and polyoxyethylene hydrogenated castor oil are selected. One type or two or more types are more preferable. Further, from the viewpoint of promptly eliminating the astringent feeling and the squeaky feeling after applying the toothpaste composition of the present invention into the oral cavity, it is preferable to contain two or more kinds of the component (B), and at least polyoxyethylene sorbitan fatty acid ester. It is more preferable to contain polyoxyethylene sorbitan fatty acid ester and polyoxyethylene hydrogenated castor oil.

The polyoxyethylene sorbitan fatty acid ester is preferably carbon from the viewpoint of achieving a good convergence and squeaky feeling after application while maintaining good tooth whitening effect and gloss-imparting effect by the component (A). It is derived from a fatty acid having 6 or more carbon atoms, more preferably derived from a fatty acid having 12 or more carbon atoms, preferably derived from a fatty acid having 22 or less carbon atoms, and more preferably derived from a fatty acid having 20 or less carbon atoms. One kind or two or more kinds selected from the thing is mentioned. From the same viewpoint, the average number of moles of ethoxy group added in the polyoxyethylene sorbitan fatty acid ester is preferably 5 to 40 mol, more preferably 10 to 25 mol, and further preferably 15 to 25 mol. be.
Examples of such polyoxyethylene sorbitan fatty acid esters include polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monomyristate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monostearate, and polyoxyethylene monooleate. One kind or two or more kinds selected from sorbitan and the like can be mentioned. Among them, one or more selected from polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monostearate and polyoxyethylene sorbitan monooleate is preferable, and polyoxyethylene sorbitan monostearate is further used. preferable.
The average number of moles of ethyleneoxy groups added to the polyoxyethylene hydrogenated castor oil is preferably 20 to 60 mol, more preferably 40 to 60, from the viewpoint of realizing the rapid disappearance of the astringent feeling and the squeaky feeling after application. It is mol, more preferably 50-60 mol.

The polyoxyethylene alkyl ether preferably has a carbon number of carbon atoms from the viewpoint of achieving a good convergence and squeaky feeling after application while maintaining good tooth whitening effect and gloss-imparting effect by the component (A). It is derived from a fatty acid having 6 or more carbon atoms, more preferably derived from a fatty acid having 12 or more carbon atoms, preferably derived from a fatty acid having 22 or less carbon atoms, and more preferably derived from a fatty acid having 20 or less carbon atoms. One kind or two or more kinds selected from the thing is mentioned. From the same viewpoint, the average number of moles of ethoxy group added in the polyoxyethylene alkyl ether is preferably 2 to 12 mol, more preferably 4 to 10 mol, and further preferably 5 to 8 mol. ..
The polyoxyethylene alkyl ether is selected from, for example, polyoxyethylene stearyl ether, polyoxyethylene cetyl ether, polyoxyethylene lauryl ether, polyoxyethylene oleyl ether, polyoxyethylene oleyl ether, polyoxyethylene myristyl ether and the like. One type or two or more types can be mentioned. Of these, it is more preferable to use polyoxyethylene stearyl ether.

The content of the component (B) is the toothpaste of the present invention from the viewpoint of immediately expressing an appropriate astringent feeling and a squeaky feeling at the time of application while maintaining the tooth whitening effect and the gloss-imparting effect of the component (A) well. In the composition, it is preferably 0.3% by mass or more, more preferably 0.6% by mass or more, still more preferably 0.8% by mass or more, still more preferably 1.5% by mass or more. be. The content of the component (B) is preferably 4% by mass or less in the dentifrice composition of the present invention from the viewpoint of promptly eliminating the astringent feeling and the squeaky feeling after application to the oral cavity, which is more preferable. Is 3.8% by mass or less, more preferably 3.6% by mass or less, still more preferably 3.5% by mass or less. The content of the component (B) is preferably 0.3 to 4% by mass, more preferably 0.6 to 3.8% by mass, and further preferably 0.8 to 3.6% by mass. It is more preferably 1.5 to 3.5% by mass.

The toothpaste composition of the present invention contains silicic anhydride as a component (C). By containing such a component (C), in combination with the above component (B), when the dentifrice composition of the present invention is applied into the oral cavity, a good astringent feeling and a squeaky feeling are immediately developed, and after the application, the dentifrice composition is promptly developed. It is possible to eliminate the feeling of convergence and squeak and bring about an excellent feeling of cleaning.
Examples of the component (C) include one or more selected from thickening silica having an oil absorption of 200 to 400 mL / 100 g and abrasive silica having an oil absorption of 50 to 150 mL / 100 g. It is preferable to contain two or more of these, and it is more preferable to contain thickening silica and abrasive silica.
The amount of oil absorbed indicates the amount of oil that silica can support, and the measuring method is specified by the amount of oil absorbed in the boiled sardine by the method of JIS K5101-13-2 (established in 2004). Means the value.

The content of the component (C) is preferably 1 mass in the toothpaste composition of the present invention from the viewpoint of immediately developing a good astringent feeling and a squeaky feeling when the toothpaste composition of the present invention is applied into the oral cavity. % Or more, more preferably 2% by mass or more, still more preferably 3% by mass or more. Further, the content of the component (C) is preferably 30 in the dentifrice composition of the present invention from the viewpoint of quickly extinguishing the astringent feeling and the squeaky feeling after the application of the dentifrice composition of the present invention into the oral cavity. It is 0% by mass or less, more preferably 28% by mass or less, and further preferably 25% by mass or less. The content of the component (C) is preferably 1 to 30% by mass, more preferably 2 to 28% by mass, and further preferably 3 to 25% by mass.

The mass ratio ((B) / {(A) + (C)}) of the content of the component (B) to the total of the acid conversion amount of the component (A) and the content of the component (C) is the present invention. After applying the dentifrice composition into the oral cavity, it is 0.03 or more, preferably 0.04 or more, and more, from the viewpoint of promptly eliminating the astringent feeling and squeaky feeling and providing an excellent cleaning feeling. It is preferably 0.05 or more. Further, the mass ratio ((B) / {(A) + (C)}) of the content of the component (B) to the total of the acid conversion amount of the component (A) and the content of the component (C) is the present. When the toothpaste composition of the present invention is applied to the oral cavity, it is 0.3 or less from the viewpoint of immediately expressing a good astringent feeling and a squeaky feeling, and also maintaining an excellent whitening effect and a gloss-imparting effect. It is preferably 0.25 or less, and more preferably 0.15 or less. The mass ratio ((B) / {(A) + (C)}) of the content of the component (B) to the total of the acid conversion amount of the component (A) and the content of the component (C) is 0. It is 0.03 or more and 0.3 or less, preferably 0.04 to 0.28, and more preferably 0.05 to 0.25.

The mass ratio ((C) / (A)) of the content of the component (C) to the acid equivalent amount of the component (A) is such that the toothpaste composition of the present invention quickly converges after application to the oral cavity. From the viewpoint of eliminating the squeaky feeling and providing an excellent cleaning feeling, it is preferably 1 or more, more preferably 5 or more, further preferably 10 or more, preferably 300 or less, and more preferably 200. It is less than or equal to, more preferably 100 or less.

The toothpaste composition of the present invention contains polyethylene glycol as a component (D). By containing such a component (D), it contributes to the rapid onset and disappearance of a convergent feeling and a squeaky feeling, and can bring about an excellent cleaning feeling.
The content of the component (D) is preferably 0.1% by mass or more, more preferably 0.5% by mass or more, still more preferably 1% by mass or more in the toothpaste composition of the present invention. , It is preferably 10% by mass or less, more preferably 8% by mass or less, and further preferably 6% by mass or less. The content of the component (D) is preferably 0.1 to 10% by mass, more preferably 0.5 to 8% by mass, and even more preferably 1 to 1% by mass in the toothpaste composition of the present invention. It is 6% by mass.

The dentifrice composition of the present invention further contains water (E). Such water includes not only purified water and the like blended in the toothpaste composition, but also water contained in each of the blended components, such as a 70% sorbitol solution (aqueous solution) used when prescribing, a toothpaste composition. It means the total water contained in it. By containing the water of the component (E), the components (A) to (D) are satisfactorily dissolved or dispersed, and the tooth whitening effect and the gloss-imparting effect of the component (A) are more satisfactorily maintained. On the other hand, an excellent cleaning feeling can be exhibited by realizing the rapid onset and disappearance of a feeling of convergence and a feeling of squeaking.

The content of the component (E) in the toothpaste composition of the present invention is preferably 5% by mass or more, more preferably 10% by mass or more, still more preferably 15% by mass or more, and preferably 95% by mass or more. It is 0% by mass or less, and more preferably 80% by mass or less. The content of the component (E) in the toothpaste composition of the present invention is preferably 5 to 95% by mass, more preferably 10 to 80% by mass, and further preferably 15 to 80% by mass. be.
The water content can be calculated from the blended water content and the water content in the blended components, but can be measured by, for example, a Karl Fischer titer. As the Karl Fischer titer, for example, a trace moisture measuring device (manufactured by Hiranuma Sangyo Co., Ltd.) can be used. In this device, 5 g of the toothpaste composition is taken, suspended in 25 g of anhydrous methanol, and 0.02 g of this suspension can be separated to measure the water content.

The fluorinated composition of the present invention is a fluorine ion supply compound selected from sodium fluoride, potassium fluoride, and ammonium fluoride from the viewpoint of avoiding unnecessarily reducing the whitening effect and gloss-imparting effect of the component (A). It is preferable that (F) is not contained, or the content thereof is 100 ppm or less in terms of fluorine atom equivalent. The content of the fluorine ion supply compound (F) in the toothpaste composition of the present invention is preferably 100 ppm or less, more preferably 80 ppm or less, still more preferably 50 ppm or less in terms of fluorine atom equivalent. Alternatively, it is preferable that the toothpaste composition of the present invention does not substantially contain the fluorine ion supply compound (F).

The toothpaste composition of the present invention does not contain a polyvalent metal cation or contains a component (A) from the viewpoint of avoiding insolubilization of the component (A) and unnecessarily reducing the whitening effect and the gloss-imparting effect. ) Is preferably contained in an amount of less than 0.1 times the molar amount. The total content of polyvalent metal cations was measured by ICP emission spectrometry (ICP emission spectrometer: Optima 5300DV manufactured by PerkinElmer), and is preferably 0.1 times the molar amount of the acid equivalent of component (A). It is preferably less than, more preferably 0.02 times by mole or less, or the toothpaste composition of the present invention is substantially free of polyvalent metal cations. Therefore, it is desirable not to add an agent that supplies one or more multivalent metal cations selected from aluminum, calcium, magnesium, iron, zinc, tin and the like.
In addition, if it is a component containing a polyvalent metal, for example, even if it is an insoluble polyvalent metal salt and exists in the composition as a powder, the polyvalent metal cation is released, and the whitening effect of the component (A) can be obtained. It tends to reduce the gloss-imparting effect.

The toothpaste composition of the present invention can contain monofluorophosphate or an alkali metal salt thereof from the viewpoint of satisfactorily exerting the whitening effect and the gloss-imparting effect of the component (A).
Examples of the alkali metal of the alkali metal salt include sodium and potassium, and sodium is preferable. The content of monofluorophosphate or an alkali metal salt thereof is preferably 0.08 to 1.5% by mass, more preferably 0.4 to 1.4% by mass in the toothpaste composition of the present invention. Yes, more preferably 0.6 to 1.3% by mass.

The dentifrice composition of the present invention is a binder from the viewpoint of retaining and diffusing the composition in the vicinity of the tooth surface while having an appropriate viscosity, and sufficiently exerting the whitening effect and the gloss-imparting effect of the component (A). It can contain a cellulosic binder as a toothpaste. Specific examples of such a cellulosic binder include one or more selected from carboxymethyl cellulose or a salt thereof, and hydroxyalkyl cellulose such as hydroxyethyl cellulose and hydroxypropyl cellulose, and carboxymethyl cellulose or The salt is preferred.
Examples of the salt of carboxymethyl cellulose include alkali metal salts such as sodium and potassium, ammonium salts and the like, and among them, sodium carboxymethyl cellulose is preferable.
The content of the cellulosic binder in the toothpaste composition of the present invention is preferably 0.1 to 2% by mass, more preferably 0.2 to 1.8% by mass, and further preferably 0. .3 to 1.6% by mass.

Further, the dentifrice composition of the present invention may contain a binder other than the above-mentioned cellulosic binder. Examples of the binder other than the cellulosic binder include xanthan gum, sodium alginate, carrageenan, sodium polyacrylate, pectin, tragant gum, arabic gum, guar gum, karaya gum, locust bean gum, gellan gum, tamarind gum, and psyllium seed. One or more selected from the group consisting of gum, polyvinyl alcohol, sodium chondroitin sulfate, methoxyethylene maleic anhydride copolymer and the like can be mentioned. Of these, xanthan gum is preferable, and it is more preferable to use the above-mentioned cellulosic binder and xanthan gum in combination. The content of the binder other than the cellulosic binder is preferably 0.01 to 1% by mass, more preferably 0.05 to 0.8% by mass in the toothpaste composition of the present invention. Yes, more preferably 0.1 to 0.6% by mass.

From the viewpoint of effectively and efficiently exerting the effects of the present invention, the toothpaste composition of the present invention contains an alkyl sulfate such as sodium lauryl sulfate, an acylmethyl taurine salt, an N-acyl amino acid salt, and an alkyl phosphate as a foaming agent. One or more anionic surfactants selected from salts, higher fatty acid sulfonated monoglycerides, fatty acid ester salts, polyoxyalkyl phosphates, alkylbenzene sulfonates, alkyl sulfoacetates and α-olefin sulfonates. Is preferably contained. Of these, sodium lauryl sulfate is preferable.
The content of such anionic surfactant is preferably 0.1 to 5% by mass, and 0.3 to 3% by mass in the dentifrice composition of the present invention.

In addition to the above components, the toothpaste composition of the present invention contains a wetting agent other than the component (D) such as glycerin; sugar alcohols such as sorbitol, erythritol, reduced palatinol, and mannitol; pH. A regulator; a surfactant other than the component (B) and the anionic surfactant; a bactericide; a preservative; a fragrance; a dye; an abrasive; granules and the like can be contained.

The toothpaste composition of the present invention promptly eliminates the previously recognized astringent feeling and squeaky feeling derived from the component (A) after applying the dentifrice composition of the present invention into the oral cavity, and provides a comfortable astringent feeling and squeaky feeling. The pH at 25 ° C. is preferably 5.0 or more, more preferably 5.5 or more, preferably 7.0 or less, and more preferably 6.8 or less.

The viscosity of the toothpaste composition of the present invention at 25 ° C. provides a good cleaning feeling by realizing the rapid onset and disappearance of a convergent feeling and a squeaky feeling while maintaining good tooth whitening effect and gloss-imparting effect. From the viewpoint, it is preferably 1500 dPa · s or more, more preferably 1700 dPa · s or more, preferably 4000 dPa · s or less, and more preferably 3500 dPa · s or less. The viscosity of the dentifrice composition of the present invention at 25 ° C. is preferably 1500 to 4000 dPa · s, and more preferably 1700 to 3500 dPa · s.
Here, the viscosity is determined by using a helipas type viscometer (VISCOMETER TVB-10 manufactured by Toki Sangyo Co., Ltd.), setting the measurement temperature to 25 ° C., rotor TC, rotation speed 2.5 r / min, and measurement conditions for 1 minute. Can be measured.

Specific forms of the dentifrice composition of the present invention include dentifrice compositions, coating agents, mouthwashes, liquid dentifrices and the like. Among them, the toothpaste composition is preferable from the viewpoint of fully enjoying the effects of the toothpaste composition of the present invention.
The dentifrice composition of the present invention is applied to the oral cavity by application, brushing with a toothbrush, or gargle, and after application, water is contained in the oral cavity and used. From the time when the toothpaste composition of the present invention is applied into the oral cavity to the time when water is contained in the oral cavity and the toothpaste is swallowed, a comfortable feeling of convergence and a squeaky feeling can be immediately perceived. After being contained in the oral cavity, the feeling of convergence and squeaky disappears quickly, and an excellent feeling of cleansing can be realized. Convergent and squeaky feelings that realize rapid onset and disappearance and bring about an excellent cleansing sensation include, specifically, the convergent sensation and squeaky feeling immediately after the mouth contains water and starts to squeeze. The time until the time when the sensation disappears can be used as an index, and the time required is preferably 5 minutes or less, more preferably 4 minutes or less, and further preferably 3 minutes or less.

Hereinafter, the present invention will be specifically described based on examples. Unless otherwise specified in the table, the content of each component indicates mass%.

[Examples 1 to 7, Comparative Examples 1 to 3]
Each dentifrice composition was produced according to the formulation shown in Table 1. Using the obtained toothpaste composition, measurement and evaluation were carried out according to the following method.
The results are shown in Table 1.

<< Measurement of pH >>
10 mL of purified water was added to 1 g of each toothpaste composition, and the pH of 25 ° C. was measured using pH / ION METER F53 (manufactured by HORIBA) for the well-shaken solution.

《Measurement of time from the onset of convergence and squeak to the disappearance》
1 g of the toothpaste composition was taken on a toothbrush and brushed freely for about 2 minutes. Regarding the feeling of convergence and squeak that is immediately felt after rinsing with water in the oral cavity, the time from immediately after rinsing until the feeling of convergence and squeaking disappeared was measured. It is shown that the shorter the time is, the more comfortable the convergent feeling and the squeaky feeling are brought about, and it is possible to realize a clean and comfortable excellent washing feeling after washing.

Claims (8)

The following components (A) to (D):
(A) Phytic acid or its salt acid equivalent amount of 0.01% by mass or more and 1.0% by mass or less (B) Nonionic surfactant (C) Silica anhydride (D) Polyethylene glycol is contained.
The mass ratio ((B) / {(A) + (C)}) of the content of the component (B) to the total of the acid conversion amount of the component (A) and the content of the component (C) is 0.03 or more. Toothpaste composition of 0.3 or less. One or more of the component (B) selected from polyoxyethylene sorbitan fatty acid ester, polyoxyethylene hydrogenated castor oil, polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyglycerin fatty acid ester and sucrose fatty acid ester. The toothpaste composition according to claim 1. The toothpaste composition according to claim 1 or 2, wherein the content of the component (B) is 0.3% by mass or more and 4% by mass or less. The toothpaste composition according to any one of claims 1 to 3, wherein the content of the component (C) is 1% by mass or more and 30% by mass or less. The toothpaste composition according to any one of claims 1 to 4, wherein the content of the component (D) is 0.1% by mass or more and 10% by mass or less. Any 1 of claims 1 to 5 which does not contain the fluorine ion supply compound (E) selected from sodium fluoride, potassium fluoride, and ammonium fluoride, or whose content is 100 ppm or less in terms of fluorine atom equivalent. The toothpaste composition according to the section. The toothpaste according to any one of claims 1 to 6, wherein the mass ratio ((C) / (A)) of the content of the component (C) to the content of the component (A) is 1 or more and 300 or less. Composition. The toothpaste composition according to any one of claims 1 to 7, wherein the pH at 25 ° C. is 5.0 or more and 7.0 or less.