JP6930919B2 - 結腸洗浄及び胃腸障害の治療のための組成物 - Google Patents

結腸洗浄及び胃腸障害の治療のための組成物 Download PDF

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JP6930919B2
JP6930919B2 JP2017557067A JP2017557067A JP6930919B2 JP 6930919 B2 JP6930919 B2 JP 6930919B2 JP 2017557067 A JP2017557067 A JP 2017557067A JP 2017557067 A JP2017557067 A JP 2017557067A JP 6930919 B2 JP6930919 B2 JP 6930919B2
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xaa
cys
peptide
missing
cth
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Japanese (ja)
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JP2018519254A (ja
JP2018519254A5 (enExample
Inventor
マーク ジー． キュリー，
マーク ジー． キュリー，
ロバート ソリンガ，
ロバート ソリンガ，
クリストファー レーザイサー，
クリストファー レーザイサー，
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Ironwood Pharmaceuticals Inc
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Ironwood Pharmaceuticals Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2017557067A 2015-05-01 2016-04-29 結腸洗浄及び胃腸障害の治療のための組成物 Active JP6930919B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562156077P 2015-05-01 2015-05-01
US62/156,077 2015-05-01
PCT/US2016/030061 WO2016178979A1 (en) 2015-05-01 2016-04-29 Compositions for colon cleansing and the treatment of gastrointestinal disorders

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020165328A Division JP2020203954A (ja) 2015-05-01 2020-09-30 結腸洗浄及び胃腸障害の治療のための組成物

Publications (3)

Publication Number Publication Date
JP2018519254A JP2018519254A (ja) 2018-07-19
JP2018519254A5 JP2018519254A5 (enExample) 2019-05-30
JP6930919B2 true JP6930919B2 (ja) 2021-09-01

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Family Applications (5)

Application Number Title Priority Date Filing Date
JP2017557067A Active JP6930919B2 (ja) 2015-05-01 2016-04-29 結腸洗浄及び胃腸障害の治療のための組成物
JP2020165328A Withdrawn JP2020203954A (ja) 2015-05-01 2020-09-30 結腸洗浄及び胃腸障害の治療のための組成物
JP2022107644A Pending JP2022121734A (ja) 2015-05-01 2022-07-04 結腸洗浄及び胃腸障害の治療のための組成物
JP2023208395A Active JP7862355B2 (ja) 2015-05-01 2023-12-11 結腸洗浄及び胃腸障害の治療のための組成物
JP2025134346A Pending JP2025169325A (ja) 2015-05-01 2025-08-12 結腸洗浄及び胃腸障害の治療のための組成物

Family Applications After (4)

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JP2020165328A Withdrawn JP2020203954A (ja) 2015-05-01 2020-09-30 結腸洗浄及び胃腸障害の治療のための組成物
JP2022107644A Pending JP2022121734A (ja) 2015-05-01 2022-07-04 結腸洗浄及び胃腸障害の治療のための組成物
JP2023208395A Active JP7862355B2 (ja) 2015-05-01 2023-12-11 結腸洗浄及び胃腸障害の治療のための組成物
JP2025134346A Pending JP2025169325A (ja) 2015-05-01 2025-08-12 結腸洗浄及び胃腸障害の治療のための組成物

Country Status (23)

Country Link
US (2) US10618938B2 (enExample)
EP (2) EP4218789A3 (enExample)
JP (5) JP6930919B2 (enExample)
KR (2) KR20250042844A (enExample)
CN (2) CN114716514A (enExample)
CA (2) CA3172777A1 (enExample)
CY (1) CY1126031T1 (enExample)
DK (1) DK3288578T5 (enExample)
EA (1) EA201792401A1 (enExample)
ES (1) ES2947591T3 (enExample)
FI (1) FI3288578T3 (enExample)
HR (1) HRP20230381T1 (enExample)
HU (1) HUE061954T2 (enExample)
LT (1) LT3288578T (enExample)
MA (1) MA41985B1 (enExample)
MD (1) MD3288578T2 (enExample)
MX (2) MX2017013928A (enExample)
PL (1) PL3288578T3 (enExample)
PT (1) PT3288578T (enExample)
RS (1) RS64160B1 (enExample)
SI (1) SI3288578T1 (enExample)
SM (1) SMT202300114T1 (enExample)
WO (1) WO2016178979A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024015335A (ja) * 2015-05-01 2024-02-01 アイアンウッド ファーマシューティカルズ インコーポレイテッド 結腸洗浄及び胃腸障害の治療のための組成物

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3464336T1 (sl) 2016-06-01 2022-06-30 Athira Pharma, Inc. Spojine
CA3238634A1 (en) * 2021-11-24 2023-06-01 Christopher Leitheiser Synthetic process for production of modified gcc receptor agonists
WO2023097210A1 (en) * 2021-11-24 2023-06-01 Ironwood Pharmaceuticals, Inc. Synthetic process for production of modified gcc receptor agonists
EP4440595A1 (en) * 2021-11-29 2024-10-09 Ironwood Pharmaceuticals, Inc. Pharmaceutical compositions for the treatment of visceral pain
WO2026050206A1 (en) * 2024-08-27 2026-03-05 Ironwood Pharmaceuticals, Inc. Combinations of glp-1 and guanylate cyclase c (gc-c) receptor agonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH689139A5 (de) 1995-04-03 1998-10-30 Cerbios Pharma Sa Verfahren zur Herstellung einer liposomalen, in Wasser dispergierbaren, oral zu verabreichenden, festen, trockenen therapeutischen Formulierung.
US5912014A (en) 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
BR122018074353B8 (pt) * 2003-01-28 2023-05-02 Ironwood Pharmaceuticals Inc composição farmacêutica, polipeptídeo e métodos para a produção dos mesmos
US7494979B2 (en) * 2003-06-13 2009-02-24 Ironwood Pharmaceuticals, Inc. Method for treating congestive heart failure and other disorders
EP1940441A4 (en) * 2005-08-19 2010-01-27 Ironwood Pharmaceuticals Inc COMPOSITIONS AND METHODS FOR TREATING GASTROINTESTINAL DISORDERS
US20110172126A1 (en) * 2008-09-03 2011-07-14 Xenome Ltd Libraries of peptide conjugates and methods for making them
CA2790213A1 (en) * 2010-02-17 2011-08-25 Ironwood Pharmaceuticals, Inc. Treatments for gastrointestinal disorders
MX357121B (es) * 2011-03-01 2018-06-27 Synergy Pharmaceuticals Inc Star Proceso de preparacion de agonistas c de guanilato ciclasa.
EP2958577A2 (en) * 2013-02-25 2015-12-30 Synergy Pharmaceuticals Inc. Guanylate cyclase receptor agonists for use in colonic cleansing
PL3004138T3 (pl) * 2013-06-05 2024-07-29 Bausch Health Ireland Limited Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie
WO2016015055A1 (en) 2014-07-25 2016-01-28 Ironwood Pharmaceuticals, Inc. Colon cleansing compositions
US10618938B2 (en) 2015-05-01 2020-04-14 Ironwood Pharmaceuticals, Inc. Compositions for colon cleansing and the treatment of gastrointestinal disorders

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024015335A (ja) * 2015-05-01 2024-02-01 アイアンウッド ファーマシューティカルズ インコーポレイテッド 結腸洗浄及び胃腸障害の治療のための組成物
JP7862355B2 (ja) 2015-05-01 2026-05-19 アイアンウッド ファーマシューティカルズ インコーポレイテッド 結腸洗浄及び胃腸障害の治療のための組成物

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Publication number Publication date
MD3288578T2 (ro) 2023-08-31
RS64160B1 (sr) 2023-05-31
SMT202300114T1 (it) 2023-05-12
US10618938B2 (en) 2020-04-14
CY1126031T1 (el) 2023-11-15
JP7862355B2 (ja) 2026-05-19
CN114716514A (zh) 2022-07-08
FI3288578T3 (fi) 2023-05-03
EP3288578A1 (en) 2018-03-07
EP3288578B8 (en) 2023-03-29
US20180148476A1 (en) 2018-05-31
EP3288578B1 (en) 2023-03-15
JP2025169325A (ja) 2025-11-12
EP4218789A2 (en) 2023-08-02
MA41985B1 (fr) 2023-04-28
CA2984437A1 (en) 2016-11-10
EP4218789A3 (en) 2023-09-27
CN108040482B (zh) 2022-03-29
PT3288578T (pt) 2023-03-28
WO2016178979A1 (en) 2016-11-10
LT3288578T (lt) 2023-04-25
CA3172777A1 (en) 2016-11-10
KR20250042844A (ko) 2025-03-27
ES2947591T3 (es) 2023-08-11
CA2984437C (en) 2025-11-18
JP2018519254A (ja) 2018-07-19
MX2022013283A (es) 2022-12-13
JP2024015335A (ja) 2024-02-01
JP2020203954A (ja) 2020-12-24
DK3288578T5 (da) 2024-10-07
SI3288578T1 (sl) 2023-07-31
KR20180005675A (ko) 2018-01-16
KR102783759B1 (ko) 2025-03-21
CN108040482A (zh) 2018-05-15
JP2022121734A (ja) 2022-08-19
DK3288578T3 (da) 2023-05-01
HUE061954T2 (hu) 2023-09-28
HRP20230381T1 (hr) 2023-07-07
PL3288578T3 (pl) 2023-08-14
EA201792401A1 (ru) 2018-05-31
MA41985A (fr) 2018-03-07
MX2017013928A (es) 2018-01-15
US20240199697A1 (en) 2024-06-20
BR112017023539A2 (pt) 2018-08-14

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