JP6914336B2 - 進行したｈｅｒ２発現がんの治療 - Google Patents

進行したｈｅｒ２発現がんの治療 Download PDF

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Publication number
JP6914336B2
JP6914336B2 JP2019534843A JP2019534843A JP6914336B2 JP 6914336 B2 JP6914336 B2 JP 6914336B2 JP 2019534843 A JP2019534843 A JP 2019534843A JP 2019534843 A JP2019534843 A JP 2019534843A JP 6914336 B2 JP6914336 B2 JP 6914336B2
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her2
trastuzumab
cancer
pertuzumab
pharmaceutical composition
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Japanese (ja)
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JP2020514281A5 (enExample
JP2020514281A (ja
Inventor
メアリー ビーティー，
メアリー ビーティー，
メリッサ ブラマー，
メリッサ ブラマー，
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Genentech Inc
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Genentech Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2019534843A 2016-12-28 2017-12-14 進行したｈｅｒ２発現がんの治療 Active JP6914336B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021115575A JP7234303B2 (ja) 2016-12-28 2021-07-13 進行したｈｅｒ２発現がんの治療

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662439815P 2016-12-28 2016-12-28
US62/439,815 2016-12-28
US201762457672P 2017-02-10 2017-02-10
US62/457,672 2017-02-10
US201762519599P 2017-06-14 2017-06-14
US62/519,599 2017-06-14
PCT/US2017/066286 WO2018125589A1 (en) 2016-12-28 2017-12-14 Treatment of advanced her2 expressing cancer

Related Child Applications (1)

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JP2021115575A Division JP7234303B2 (ja) 2016-12-28 2021-07-13 進行したｈｅｒ２発現がんの治療

Publications (3)

Publication Number Publication Date
JP2020514281A JP2020514281A (ja) 2020-05-21
JP2020514281A5 JP2020514281A5 (enExample) 2021-07-29
JP6914336B2 true JP6914336B2 (ja) 2021-08-04

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JP2019534843A Active JP6914336B2 (ja) 2016-12-28 2017-12-14 進行したｈｅｒ２発現がんの治療
JP2021115575A Active JP7234303B2 (ja) 2016-12-28 2021-07-13 進行したｈｅｒ２発現がんの治療

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JP2021115575A Active JP7234303B2 (ja) 2016-12-28 2021-07-13 進行したｈｅｒ２発現がんの治療

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US (2) US20180221481A1 (enExample)
EP (1) EP3562844A1 (enExample)
JP (2) JP6914336B2 (enExample)
KR (1) KR102313262B1 (enExample)
CN (1) CN110099926A (enExample)
AU (2) AU2017387909A1 (enExample)
CA (1) CA3046092A1 (enExample)
IL (1) IL267675A (enExample)
MX (1) MX2019007801A (enExample)
TW (1) TW201827077A (enExample)
WO (1) WO2018125589A1 (enExample)

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JP6992081B2 (ja) 2017-03-02 2022-02-03 ジェネンテック， インコーポレイテッド Ｈｅｒ２陽性乳癌のアジュバント治療
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CN114025795B (zh) * 2019-05-31 2025-04-29 酵活英属哥伦比亚有限公司 使用靶向her2的双特异性抗原结合构建体治疗胆道癌的方法
US12233177B2 (en) 2019-09-16 2025-02-25 Amgen Inc. Method for external sterilization of drug delivery device
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WO2022022526A1 (zh) * 2020-07-28 2022-02-03 百奥泰生物制药股份有限公司 抗her2抗体及其应用
CN115957321A (zh) * 2023-03-03 2023-04-14 盛禾(中国)生物制药有限公司 一种抗her2抗体在制备治疗癌症的药物中的用途

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Publication number Publication date
US20180221481A1 (en) 2018-08-09
KR20190094228A (ko) 2019-08-12
AU2017387909A1 (en) 2019-06-27
CN110099926A (zh) 2019-08-06
MX2019007801A (es) 2019-10-30
US20200237910A1 (en) 2020-07-30
JP2021178832A (ja) 2021-11-18
TW201827077A (zh) 2018-08-01
CA3046092A1 (en) 2018-07-05
EP3562844A1 (en) 2019-11-06
JP7234303B2 (ja) 2023-03-07
KR102313262B1 (ko) 2021-10-14
AU2021201516A1 (en) 2021-04-01
JP2020514281A (ja) 2020-05-21
WO2018125589A1 (en) 2018-07-05
IL267675A (en) 2019-08-29

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