JP6903594B2 - 食品、栄養補助食品、化粧品および医薬品に有用な複数の相乗的抗酸化活性を示すフィトコンプレックス - Google Patents

食品、栄養補助食品、化粧品および医薬品に有用な複数の相乗的抗酸化活性を示すフィトコンプレックス Download PDF

Info

Publication number
JP6903594B2
JP6903594B2 JP2017568013A JP2017568013A JP6903594B2 JP 6903594 B2 JP6903594 B2 JP 6903594B2 JP 2017568013 A JP2017568013 A JP 2017568013A JP 2017568013 A JP2017568013 A JP 2017568013A JP 6903594 B2 JP6903594 B2 JP 6903594B2
Authority
JP
Japan
Prior art keywords
extract
composition
grape
disease
therapeutic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2017568013A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018510217A5 (enExample
JP2018510217A (ja
Inventor
エル. トリップ、マシュー
エル. トリップ、マシュー
ジェイ. ダールバーグ、クリントン
ジェイ. ダールバーグ、クリントン
ジー. バビッシュ、ジョン
ジー. バビッシュ、ジョン
ガオ、ウェイ
カーディジ、モハン
クリッグ、シェリル
コウ、シャオラン
カン、ヂゥー
オウ、ジョセフ
Original Assignee
ネイチャーズ サンシャイン プロダクツ、インク.
ネイチャーズ サンシャイン プロダクツ、インク.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ネイチャーズ サンシャイン プロダクツ、インク., ネイチャーズ サンシャイン プロダクツ、インク. filed Critical ネイチャーズ サンシャイン プロダクツ、インク.
Publication of JP2018510217A publication Critical patent/JP2018510217A/ja
Publication of JP2018510217A5 publication Critical patent/JP2018510217A5/ja
Application granted granted Critical
Publication of JP6903594B2 publication Critical patent/JP6903594B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/38Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/45Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pediatric Medicine (AREA)
  • Physiology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Cosmetics (AREA)
JP2017568013A 2015-03-16 2016-03-16 食品、栄養補助食品、化粧品および医薬品に有用な複数の相乗的抗酸化活性を示すフィトコンプレックス Active JP6903594B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562133945P 2015-03-16 2015-03-16
US62/133,945 2015-03-16
PCT/US2016/022720 WO2016149424A1 (en) 2015-03-16 2016-03-16 Phytocomplexes exhibiting multiple, synergistic antioxidant activities useful in foods, dietary supplements, cosmetics and pharmaceutical preparations

Publications (3)

Publication Number Publication Date
JP2018510217A JP2018510217A (ja) 2018-04-12
JP2018510217A5 JP2018510217A5 (enExample) 2019-04-18
JP6903594B2 true JP6903594B2 (ja) 2021-07-14

Family

ID=56919277

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017568013A Active JP6903594B2 (ja) 2015-03-16 2016-03-16 食品、栄養補助食品、化粧品および医薬品に有用な複数の相乗的抗酸化活性を示すフィトコンプレックス

Country Status (12)

Country Link
US (2) US10434131B2 (enExample)
EP (1) EP3270707B1 (enExample)
JP (1) JP6903594B2 (enExample)
KR (2) KR20180021674A (enExample)
CN (1) CN107920561A (enExample)
CA (1) CA2979690C (enExample)
ES (1) ES2846909T3 (enExample)
HK (1) HK1252943A1 (enExample)
MX (1) MX385569B (enExample)
PL (1) PL3270707T3 (enExample)
SI (1) SI3270707T1 (enExample)
WO (1) WO2016149424A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX385569B (es) * 2015-03-16 2025-03-18 Natures Sunshine Products Inc Fitocomplejos que exhiben actividades antioxidantes sinérgicas, múltiples, útiles en alimentos, suplementos alimenticios, cosméticos y preparaciones farmacéuticas.
EP3426061A4 (en) * 2016-03-07 2019-11-13 Nature's Sunshine Products Inc. METHOD AND COMPOSITIONS FOR IMPROVING WEIGHT DECREASE AND CARDIOMETABOLIC HEALTH OVER DIET AND EXERCISE
CN111295203B (zh) * 2017-08-11 2022-09-06 深圳君圣泰生物技术有限公司 用于治疗炎症性肠病的方法和组合物
US12194065B2 (en) 2017-11-03 2025-01-14 Nature's Sunshine Products, Inc. Methods and compositions to enhance metabolic detoxification systems
ES2955586T3 (es) * 2018-02-02 2023-12-04 Indena Spa Composiciones que comprenden berberina
US11191289B2 (en) 2018-04-30 2021-12-07 Kraft Foods Group Brands Llc Spoonable smoothie and methods of production thereof
US11207293B2 (en) * 2018-07-01 2021-12-28 Anthony Stampalia Therapeutic compositions and uses thereof
CN108524713A (zh) * 2018-07-05 2018-09-14 天津益倍元天然产物技术有限公司 改善男性前列腺健康的功能性组合物及其制备方法和应用
IT201900020808A1 (it) * 2019-11-11 2021-05-11 Neilos S R L Composizione per la riduzione del rischio cardiovascolare
WO2021158825A1 (en) * 2020-02-05 2021-08-12 DailyColors Health Inc. Compositions and methods for nutritional supplements
WO2021220050A1 (en) * 2020-05-01 2021-11-04 Health And Happiness (H&H) Hong Kong Limited New compositions useful for treating elevated blood lipid levels
EP4156973A1 (en) 2020-05-25 2023-04-05 Metaceutic Aps Nutraceutical composition
IT202100002564A1 (it) * 2021-02-05 2022-08-05 Biofficina Srls Bevanda funzionale detossificante
AU2022304700A1 (en) 2021-06-28 2024-02-08 DailyColors Health Inc. Compositions and methods to counteract processes associated with inflammation and senescence and to support cellular energy and/or metabolism
CN117858630A (zh) * 2021-06-28 2024-04-09 日彩健康有限公司 对抗与炎症和衰老相关的过程并支持细胞能量和/或代谢的组合物和方法
IT202200008879A1 (it) * 2022-05-03 2023-11-03 Neilos S R L “Composizione nutraceutica o farmaceutica per la salute cardiovascolare”
IT202300006831A1 (it) 2023-04-06 2024-10-06 Dompe Farm Spa Composizione a base di estratti vegetali utile per il trattamento delle dislispidemie

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0026018D0 (en) 2000-10-24 2000-12-13 Novartis Nutrition Ag New composition
WO2002072040A1 (en) * 2001-03-13 2002-09-19 Ajinomoto Co., Inc. Comsetics or external preparaiotns for skin
US7999003B2 (en) * 2003-08-26 2011-08-16 Mannatech, Incorporated Antioxidant compositions and methods thereto
US20060088643A1 (en) 2004-10-27 2006-04-27 Nature's Sunshine Products, Inc. Neutraceutical composition containing mangosteen pericarp extract
US20060172012A1 (en) 2005-01-28 2006-08-03 Finley John W Anti-inflammatory supplement compositions and regimens to reduce cardiovascular disease risks
US8962058B2 (en) * 2005-11-23 2015-02-24 The Coca-Cola Company High-potency sweetener composition with antioxidant and compositions sweetened therewith
ITTO20060239A1 (it) 2006-03-30 2007-09-30 Rotthapharm S P A Formulazione per somministrazione orale con effetti salutistici sull'apparato cardiovascolare
US8968791B2 (en) * 2007-06-06 2015-03-03 Novus International, Inc. Dietary supplements for promotion of growth, repair, and maintenance of bone and joints
EP2022344A1 (en) * 2007-08-02 2009-02-11 Nestec S.A. Reduction of fatigue as a result of exercise
US20100215783A1 (en) * 2009-02-23 2010-08-26 Nutragenesis, Llc Antioxidant Compositions, Beverage Formulations Thereof, and Methods of Increasing Antioxidant Capability
ES2592202T3 (es) * 2009-04-28 2016-11-28 Wm. Wrigley Jr. Company Composiciones orales para beneficios cutáneos
CA2792018A1 (en) * 2010-05-10 2011-11-17 Segetis, Inc. Fragrant formulations, methods of manufacture thereof and articles comprising the same
US8435541B2 (en) * 2010-09-02 2013-05-07 Bath & Body Works Brand Management, Inc. Topical compositions for inhibiting matrix metalloproteases and providing antioxidative activities
WO2012129683A1 (en) * 2011-03-25 2012-10-04 Biopharmacopae Design International Inc. Extracts from plants of the tsuga genus and uses thereof in the treatment of skin disorders
US8916528B2 (en) 2011-11-16 2014-12-23 Resveratrol Partners, Llc Compositions containing resveratrol and nucleotides
US20140023737A1 (en) * 2012-04-10 2014-01-23 The Regents Of The University Of California Modulation of Oxidative Stress, Inflammation, and Impaired Insulin Sensitivity with Grape seed Extract
WO2014088520A1 (en) 2012-12-03 2014-06-12 Eraslan Mustafa Usage of fig fruit extract and olive leaf extract combinations together with green tea and grape seed extracts
CA2921630A1 (en) * 2013-08-20 2015-02-26 Schweitzer-Mauduit International, Inc. Product comprising a plant for medicinal, cosmetic, coloring or dermatologic use
MX385569B (es) * 2015-03-16 2025-03-18 Natures Sunshine Products Inc Fitocomplejos que exhiben actividades antioxidantes sinérgicas, múltiples, útiles en alimentos, suplementos alimenticios, cosméticos y preparaciones farmacéuticas.

Also Published As

Publication number Publication date
US10434131B2 (en) 2019-10-08
MX2017011830A (es) 2018-04-20
US20170020948A1 (en) 2017-01-26
US11331363B2 (en) 2022-05-17
JP2018510217A (ja) 2018-04-12
PL3270707T3 (pl) 2021-05-31
MX385569B (es) 2025-03-18
ES2846909T3 (es) 2021-07-30
SI3270707T1 (sl) 2021-04-30
CN107920561A (zh) 2018-04-17
CA2979690C (en) 2024-09-10
CA2979690A1 (en) 2016-09-22
HK1252943A1 (zh) 2019-06-06
KR20250017295A (ko) 2025-02-04
EP3270707A4 (en) 2018-12-05
EP3270707B1 (en) 2020-10-28
EP3270707A1 (en) 2018-01-24
WO2016149424A1 (en) 2016-09-22
US20200246412A1 (en) 2020-08-06
KR20180021674A (ko) 2018-03-05

Similar Documents

Publication Publication Date Title
JP6903594B2 (ja) 食品、栄養補助食品、化粧品および医薬品に有用な複数の相乗的抗酸化活性を示すフィトコンプレックス
US20220296552A1 (en) Compositions and methods for acutely raising nitic oxide levels
Zuraini et al. Promising nutritional fruits against cardiovascular diseases: An overview of experimental evidence and understanding their mechanisms of action
Akinyemi et al. Effect of dietary supplementation of ginger and turmeric rhizomes on angiotensin-1 converting enzyme (ACE) and arginase activities in L-NAME induced hypertensive rats
Bergamin et al. Nutraceuticals: Reviewing their role in chronic disease prevention and management
KR20190007412A (ko) 식이 및 운동 후 체중 감량 및 심대사 건강을 향상시키는 방법 및 조성물
US10166267B1 (en) Multi-component formulations for the treatment of cognitive decline including Alzheimer's disease
Donado-Pestana et al. Cagaita fruit (Eugenia dysenterica DC.) and obesity: Role of polyphenols on already established obesity
JP2018518513A (ja) 天然の化合物および/または規定食を用いた炎症の治療方法
JP2019068825A (ja) 抗酸化栄養補助食品と、それに関連する方法
Anioke et al. Investigation into hypoglycemic, antihyperlipidemic, and renoprotective potentials of Dennettia tripetala (Pepper Fruit) seed in a rat model of diabetes
CA2814404A1 (en) Coffee extracts as ingredients of foods, drugs, cosmetics, dietary supplements, and biologics
CN102686113A (zh) 粗品咖啡因复合物、使用所述粗品咖啡因复合物的改进的食品及其使用方法
Oso et al. Assessment of in vitro biological properties of aqueous extracts of Murraya koenigii L. Spreng., Thymus vulgaris L., and Ocimum gratissimum L. leaves
US20250108082A1 (en) Therapeutic combinations for inflammatory conditions and disorders
Rajalekshmi et al. Potential Role of Nutraceuticals in the Prevention of Cardiovascular Toxicity
Sanger et al. Functional Beverage Made with the Seaweed Caulerpa racemosa: Antioxidant and Pharmacokinetic Properties
EP4665318A2 (en) Therapeutic combinations for inflammatory conditions and disorders
Yance Cholesterol, Statins and the Truth about Cardiovascular Health and
HK1262460A1 (en) Compositions and methods for acutely raising nitic oxide levels
Davies Plenary Lectures and Oral Presentations

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190311

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20190311

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20191210

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20200306

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20200507

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20200609

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20201013

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20201219

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210408

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20210525

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20210623

R150 Certificate of patent or registration of utility model

Ref document number: 6903594

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250