JP6869793B2 - Ophthalmic devices, their control methods, and programs - Google Patents

Description

The present invention is an ophthalmic apparatus configured so that a plurality of objective lenses having different magnifications can be exchanged as objective lenses arranged at positions facing the eye to be inspected, a control method thereof, and a computer for executing the control method. It's about the program.

Currently, ophthalmic devices for observing and photographing the eye include, for example, anterior ocular segment imaging device, fundus camera, confocal laser scanning ophthalmoscope (SLO) device, and light using multi-wavelength optical wave interference. There are optical coherence tomography (OCT) devices and the like. Above all, the OCT device is becoming an indispensable device in the specialized outpatient department of the retina as an ophthalmic device because it can obtain a tomographic image of the subject with high resolution, and it is also used not only for ophthalmology but also for endoscopes and the like. It's being used.

When an OCT device is used as an ophthalmologic device, for example, due to an eye disease, a wide range may be photographed so as to include the peripheral part of the fundus, or a specific part of the fundus may be imaged with high resolution, that is, the optical magnification may be changed. It is required to take a picture. In this regard, for example, Patent Document 1 discloses an ophthalmic apparatus that changes the optical magnification by attaching and detaching an optical member for variable magnification between the eye to be inspected and the objective lens.

Japanese Unexamined Patent Publication No. 2011-147612

However, in the ophthalmic apparatus described in Patent Document 1, since an optical member for scaling is added to the measurement optical system, the fixation target for fixing the eye to be inspected is also scaled. For this reason, there is a problem that it is difficult to stabilize the fixation of the eye to be inspected before and after the magnification is changed when the eye to be inspected is magnified for the examination.

The present invention has been made in view of such problems, and provides a mechanism capable of stabilizing the fixation of the eye to be inspected before and after the magnification is changed when the eye to be inspected is magnified for examination. The purpose is to provide.

One of the ophthalmic devices of the present invention is a projection means for projecting a fixation target for fixing an eye to be examined onto the eye to be inspected via an objective lens arranged at a position facing the eye to be inspected. A projection means including a light emitting means for emitting the fixation light according to the fixation target and a scanning means for scanning the fixation light with respect to the eye to be inspected, and a magnification of the objective lens are changed. When this is done, the scanning interval of the fixation light with respect to the eye to be inspected by the scanning means is such that the change in the scanning interval of the fixation light due to the change in the magnification is small. It has an adjusting means for adjusting the projection means related to the scanning interval.
One of the ophthalmic devices of the present invention is a projection means for projecting a fixation target for fixing an eye to be examined onto the eye to be inspected via an objective lens arranged at a position facing the eye to be inspected. A projection means including a light emitting means for emitting the fixation light according to the fixation target, a scanning means for scanning the fixation light with respect to the eye to be inspected, and a projection means for photographing the eye to be inspected. The scanning interval of the fixation light with respect to the eye to be inspected by the scanning means according to the change of the magnification corresponding to the change of the image angle related to the photographing in the optical system of the above, and the scanning interval of the fixation light based on the change of the magnification. It has an adjusting means for adjusting the projection means related to the scanning interval of the optometry light so that the change in the scanning interval becomes small.
The present invention also includes the above-mentioned control method for an ophthalmic apparatus and a program for causing a computer to execute the control method.

According to the present invention, when the test eye is magnified and the test is performed, the fixation of the eye to be inspected can be stabilized before and after the scaling.

It is a figure which shows an example of the whole structure of the ophthalmic apparatus which concerns on 1st Embodiment of this invention. It is a figure which shows the 1st Embodiment of this invention, and shows an example of the internal structure of the inspection part and the base part shown in FIG. It is a figure which shows the 1st Embodiment of this invention, and shows an example of the internal structure of the control / processing part shown in FIG. In the ophthalmic apparatus according to the first embodiment of the present invention, the SLO optical system and fixation related to the optical path when a low magnification (short focal length and wide angle of view) objective lens is arranged at a position facing the eye to be inspected. It is a figure which shows the position of the target optical system. In the ophthalmic apparatus according to the first embodiment of the present invention, the SLO optical system and fixation related to the optical path when an objective lens having a high magnification (long focal length and narrow angle of view) is arranged at a position facing the eye to be inspected. It is a figure which shows the position of the target optical system. It is a flowchart which shows an example of the processing procedure in the control method of the ophthalmic apparatus which concerns on 1st Embodiment of this invention. It is a figure which shows the 1st Embodiment of this invention, and shows an example of the fixation target when the objective lens of a different magnification is arranged at the position facing the eye to be examined. It is a figure which shows the 1st Embodiment of this invention, and shows an example of the fixation target when the objective lens of a different magnification is arranged at the position facing the eye to be examined. It is a figure which shows the 2nd Embodiment of this invention and shows an example of the internal structure of the inspection part and the base part shown in FIG. It is a figure which shows the 2nd Embodiment of this invention and shows an example of the schematic structure of the fixation target aperture shown in FIG. It is a figure which shows the 3rd Embodiment of this invention, and shows an example of the fixation target optical system which concerns on the optical path of the inspection part shown in FIG. It is a figure which shows the 4th Embodiment of this invention, and shows an example of the light emission pattern of the fixation lamp shown in FIG.

Hereinafter, embodiments (embodiments) for carrying out the present invention will be described with reference to the drawings.

(First Embodiment)
First, the first embodiment of the present invention will be described.

<Overall configuration of ophthalmic apparatus 10>
FIG. 1 is a diagram showing an example of the overall configuration of the ophthalmic apparatus 10 according to the first embodiment of the present invention. As shown in FIG. 1, the ophthalmic apparatus 10 includes an inspection unit 100, a control / processing unit 200, an input unit 300, a display unit 400, a stage unit 500, a base unit 600, and a face receiving unit 700. ing.

The inspection unit 100 irradiates the eye to be inspected (more specifically, the fundus of the eye to be inspected in this embodiment) with light based on the control of the control / processing unit 200, and emits the return light reflected / scattered from the eye to be inspected. Detect and acquire various image signals.

The control / processing unit 200 comprehensively controls the operation of the ophthalmic apparatus 10 and performs various processes. For example, the control / processing unit 200 controls the inspection unit 100, the display unit 400, the stage unit 500, and the base unit 600, and performs predetermined image processing or the like on various image signals obtained by the inspection unit 100. Do.

The input unit 300 inputs various information to the control / processing unit 200. The input unit 300 is composed of, for example, a keyboard, a mouse, or the like operated by the examiner.

The display unit 400 performs processing for displaying various images, various information, and the like based on the control of the control / processing unit 200.

The stage unit 500 moves the inspection unit 100 in the X, Y, and Z directions of FIG. 1 via a motor (not shown) under the control of the control / processing unit 200.

The base portion 600 supports the inspection portion 100 and the face receiving portion 700 via the stage portion 500. Further, the base portion 600 has a built-in spectroscope 610 shown in FIG.

The face receiving portion 700 receives the face of the subject and fixes the chin and forehead of the subject to promote the fixation of the eyes of the subject.

<< Internal configuration of inspection unit 100 and base unit 600 >>
FIG. 2 is a diagram showing a first embodiment of the present invention and showing an example of the internal configuration of the inspection unit 100 and the base unit 600 shown in FIG. Here, in FIG. 2, the inspection unit 100 in the first embodiment is described as “inspection unit 100-1”.

First, the internal configuration of the inspection unit 100-1 shown in FIG. 2 will be described.

In the inspection unit 100-1 shown in FIG. 2, the objective lens 111 is installed facing the eye E to be inspected, and the first dichroic mirror 132-1 and the second dichroic mirror 132-2 are arranged on the optical axis thereof. ing. By the first dichroic mirror 132-1 and the second dichroic mirror 132-2, the light is the SLO optical system and fixation that combine the observation of the optical path L1 and the eye E to be examined and the acquisition of the two-dimensional image of the OCT optical system. It is branched into the optical path L2 of the target optical system and the optical path L3 of the anterior eye observation optical system for each wavelength band.

Here, the objective lens 111 is held by a lens barrel 110 that holds the lens. The lens barrel 110 is provided with, for example, a mark 112 for detecting attachment / detachment, which is formed of a protrusion. The objective lens detection unit 131 detects the presence or absence of the lens barrel 110 by, for example, a proximity sensor or the like. Further, the objective lens 121 is a lens used at the time of variable magnification. Specifically, in the present embodiment, the objective lens 121 is an objective lens (second objective lens) having a higher magnification than the objective lens 111 (first objective lens). is there. The objective lens 121 is also held by the lens barrel 120, and the lens barrel 120 is provided with a mark 122 for detecting attachment / detachment at a position different from that of the lens barrel 110. Then, the objective lens detection unit 131 detects which magnification of the objective lens is attached as the objective lens arranged at the position facing the eye E to be inspected by detecting the marks 112 and 122 for detecting the attachment / detachment. can do. As shown in FIG. 2, the ophthalmic apparatus 10 according to the present embodiment is configured so that a plurality of objective lenses 111 and 121 having different magnifications can be exchanged as objective lenses arranged at positions facing the eye E to be inspected. ..

Specifically, the optical paths L2 of the SLO optical system and the fixation target optical system are, for example, an SLO optical system for capturing a fundus frontal image (SLO image) for observing the fundus Ef of the eye E to be inspected, and a fundus. It is an optical path of the fixation target optical system that presents the fixation target to Ef. Further, the optical path L1 of the OCT optical system is, for example, the optical path of the OCT optical system 130 for capturing a tomographic image (OCT image) in the fundus Ef of the eye E to be inspected. Further, the optical path L3 of the anterior eye observation optical system is an optical path of the anterior eye observation optical system for capturing an image of the anterior segment for observing the anterior segment of the eye E to be inspected.

First, the optical path L2 of the SLO optical system and the fixation target optical system will be described.

The optical path L2 includes a relay lens 141, an SLO scanning means 142, lenses 135-4 and 135-5, a mirror 132-5, a third dichroic mirror 132-4, a photodiode 153, an SLO light source 152, and a fixation lamp (solid). The optotype light source) 151 is arranged.

The mirror 132-5 is a prism on which a perforated mirror or a hollow mirror is vapor-deposited, and separates the illumination light from the SLO light source 152 and the return light from the eye E to be inspected. The third dichroic mirror 132-4 outputs the illumination light by the SLO light source 152 and the fixation light by the fixation lamp 151 separately for each wavelength band to the optical path L2.

The SLO scanning means 142 scans the illumination light from the SLO light source 152 and the fixation light from the fixation lamp 151 on the fundus Ef of the eye E to be inspected. The SLO scanning means 142 includes an X scanner that scans in the X direction of FIG. 2 and a Y scanner that scans in the Y direction of FIG. In the present embodiment, the X scanner is, for example, a scanner responsible for scanning in the main scanning direction in the SLO scanning means 142, and is required to perform high-speed scanning. Therefore, the X scanner is composed of, for example, a polygon mirror. Further, the Y scanner is, for example, a scanner responsible for scanning in the sub-scanning direction in the SLO scanning means 142, and is configured by, for example, a galvano mirror.

The SLO focus lens 135-4 is driven by, for example, a motor (not shown) for focusing the illumination light by the SLO light source 152 and the fixation light by the fixation lamp 151. The fixation lamp 151 irradiates the eye E to be examined with visible light, thereby presenting an fixation target based on the fixation light to the fundus Ef of the eye E to obtain the fixation of the eye to be inspected. It is for encouraging. The SLO light source 152 generates light having a wavelength in the vicinity of, for example, 780 nm.

The illumination light emitted from the SLO light source 152 is reflected by the third dichroic mirror 132-4, passes through the mirror 132-5, passes through the lens 135-5 and the SLO focus lens 135-4, and passes through the SLO scanning means 142. Is scanned on the fundus Ef of the eye E to be inspected. Then, the return light from the fundus Ef of the eye E to be inspected follows the same path as the illumination light, is reflected by the mirror 132-5, and is guided to the photodiode 153. The photodiode 153 detects the return light from the fundus Ef of the eye E to be inspected and acquires the SLO image signal.

Further, the optometry light emitted from the optometry lamp 151 passes through the third dichroic mirror 132-4 and the mirror 132-5, and then passes through the lens 135-5 and the SLO focus lens 135-4, and is passed through the SLO scanning means. The 142 scans on the fundus Ef of the eye E to be inspected. At this time, by blinking the fixation lamp 151 in accordance with the movement of the SLO scanning means 142, it becomes possible to form an fixation target of an arbitrary shape at an arbitrary position on the fundus Ef of the eye E to be inspected. It is possible to encourage the subject to fix his eyes.

Subsequently, the optical path L1 of the OCT optical system will be described.

The optical path L1 of the OCT optical system is the optical path of the OCT optical system 130, which is an optical system for taking an optical coherence tomography of the eye E to be inspected. More specifically, it is an optical path for obtaining an interference signal for forming a tomographic image (OCT image) of the eye to be inspected.

First, a relay lens 133, an OCT scanning means 134, a shutter 136, an OCT focus lens 135-1, and a lens 135-2 are arranged in the optical path L1 of the OCT optical system. The OCT scanning means 134 is configured to include an XY scanner for scanning the light (measurement light) from the OCT light source 101 on the fundus Er of the eye E to be inspected. Although the OCT scanning means 134 is shown as a single mirror in the example shown in FIG. 2, it scans in the X direction and the Y direction. The shutter 136 can be inserted and retracted into the optical path L1 by a drive mechanism (not shown). The OCT focus lens 135-1 directs the light (measurement light) from the OCT light source 101 emitted from the fiber end 105-1 of the optical fiber 102-2 connected to the optical coupler 103 to the fundus Ef of the eye E to be inspected. It is a focus adjusting member for focusing. The OCT focus lens 135-1 is driven by a motor (not shown) based on the control of the control / processing unit 200.

By focusing with the OCT focus lens 135-1, the return light from the fundus Ef of the eye E to be inspected is simultaneously imaged and incident on the fiber end 105-1 of the optical fiber 102-2 in a spot shape. .. Further, an optical coupler 103, an OCT light source 101, an optical fiber 102-1 to 102-4, a lens 135-3, a dispersion compensation glass 137, and a reference mirror 132-3 are arranged in the optical path L1 of the OCT optical system. There is. The optical fibers 102-1 to 102-4 are, for example, single-mode optical fibers connected to and integrated with the optical coupler 103. Further, the spectroscope 610 internally configured in the base portion 600 is connected to the optical fiber 102-4. The Michelson interference system is configured by the above configuration.

The OCT light source 101 is composed of, for example, an SLD (Super Luminate Diode) which is a typical low coherent light source. The central wavelength of the light of the OCT light source 101 is about 855 nm, and the wavelength bandwidth is about 100 nm. Here, the bandwidth is an important parameter because it affects the resolution of the obtained tomographic image in the optical axis direction. Further, although an example in which SLD is applied as the OCT light source 101 has been described here, any light source capable of emitting low coherent light may be used, and for example, ASE (Amplified Spontaneous Emission) or the like can be used. Further, as the central wavelength of the light of the OCT light source 101, near infrared light is suitable in view of measuring the eye E to be inspected. Further, since the central wavelength of the light of the OCT light source 101 affects the lateral resolution of the obtained tomographic image, it is desirable that the wavelength is as short as possible. For both of these reasons, in the embodiment, the central wavelength of the light of the OCT light source 101 is set to about 855 nm. Further, in the present embodiment, an example of applying the Michelson interference system has been described, but for example, a Mach-Zehnder interference system may be used. For example, it is desirable to use a Mach-Zehnder interference system when the light amount difference is large, and to use a Michelson interferometer when the light amount difference is relatively small, depending on the light amount difference between the measurement light and the reference light.

The optical coupler 103 is a branching member that branches the light emitted from the OCT light source 101 via the optical fiber 102-1 into the measurement light and the reference light. The measurement light branched by the optical coupler 103 is emitted toward the fundus Ef of the eye E to be observed via the optical fiber 102-2 and the objective lens. The measurement light applied to the fundus Er is reflected and scattered in the fundus Er and reaches the optical coupler 103 through the same optical path. On the other hand, the reference light passes through the optical fiber 102-3, passes through the lens 135-3 and the dispersion compensation glass 137, and is emitted toward the reference mirror 132-3. The reference light emitted to the reference mirror 132-3 is reflected by the reference mirror 132-3 and reaches the optical coupler 103 through the same optical path.

In this way, the measurement light and the reference light that have reached the optical coupler 103 are combined in the optical coupler 103 to become interference light. Here, interference occurs when the optical path length of the measurement light and the optical path length of the reference light are substantially the same. The reference mirror 132-3 is held so as to be adjustable in the optical axis direction by a motor and a drive mechanism (not shown) based on the control of the control / processing unit 200, and the reference light has an optical path length of the measurement light that changes depending on the eye E to be inspected. It is possible to match the optical path length. That is, the reference mirror 132-3 constitutes a reference light adjusting member that adjusts the optical path length of the reference light.

Further, the optical fiber 102-2 is provided with a polarization adjusting unit 104-1 on the measurement light side, and the optical fiber 102-3 is provided with a polarization adjusting unit 104-2 on the reference light side. These polarization adjusting units 104-1 and 104-2 have several portions in which the optical fiber is routed in a loop shape, and the loop-shaped portions are rotated around the longitudinal direction of the optical fiber to twist the optical fiber. In addition, it is possible to adjust and match the polarization states of the corresponding measurement light and the reference light.

Subsequently, the optical path L3 of the anterior eye observation optical system will be described.

A lens 135-6, a split prism 161 and a lens 135-7, and a CCD 162 for observing the anterior segment of the eye for detecting infrared light are arranged in the optical path L3 of the anterior segment observation optical system. The CCD 162 has a sensitivity in the wavelength of light of an irradiation light source for frontal eye observation (not shown), specifically in the vicinity of 970 nm. The split prism 161 is arranged at a position conjugate with the pupil of the eye E to be inspected, and is for detecting the distance of the inspection unit 100-1 to the eye E to be inspected in the Z direction (anterior-posterior direction) as a split image of the anterior eye portion. belongs to.

Next, the internal configuration of the base portion 600 shown in FIG. 2 will be described.

A spectroscope 610 is provided inside the base portion 600. The spectroscope 610 includes a lens 611, a diffraction grating 612, a lens 613, and a line sensor 614.

The interference light generated by the optical coupler 103 is guided to the spectroscope 610 via the optical fiber 102-4. Specifically, the interference light emitted from the optical fiber 102-4 becomes parallel light through the lens 611, is separated by the diffraction grating 612, and is imaged on the line sensor 614 by the lens 613. The line sensor 614 detects this interference light and acquires an OCT image signal.

In the present embodiment, the OCT optical system 130 shows a configuration example for capturing a tomographic image of the fundus Ef of the eye E to be inspected, but the present invention is not limited to this, for example, the cornea and the like. It may be configured to take a tomographic image of the anterior segment of the eye E to be inspected. As described above, in the OCT optical system 130, the light from the OCT light source 101 is divided into measurement light and reference light by the optical coupler 103. Then, the measurement light is emitted toward the fundus Ef of the eye E to be observed through the optical fiber 102-2 and the objective lens. Then, the return light of the measurement light from the fundus Ef is combined with the reference light reflected by the reference mirror 132-3 in the optical coupler 103, and is guided to the spectroscope 610 as interference light. The return light described here is reflected light or scattered light that includes information about the interface in the irradiation direction of light with respect to the fundus Ef of the eye E to be observed. Then, a tomographic image of the fundus Ef can be obtained by detecting and analyzing the interference light between the return light and the reference light with the spectroscope 610. At this time, in order to photograph the target area of the eye E to be inspected, it is important to acquire a two-dimensional image of the eye E to be inspected and to suppress the eye movement of the eye E to be inspected. Therefore, in the ophthalmic apparatus 10, the OCT optical system, the SLO optical system, and the fixation target optical system are realized by one objective lens, and the apparatus is simplified. Further, in the ophthalmic apparatus 10, from the viewpoint of the disease of the eye E, a wide range including the peripheral portion of the fundus Ef of the eye E is photographed, and a specific part of the fundus Ef is photographed with high resolution. In order to realize this, a plurality of objective lenses having different magnifications are interchangeably configured as one objective lens arranged at a position facing the eye E to be inspected.

<< Internal configuration of control / processing unit 200 >>
FIG. 3 is a diagram showing a first embodiment of the present invention and showing an example of the internal configuration of the control / processing unit 200 shown in FIG. In FIG. 3, the same reference numerals are given to the configurations similar to those shown in FIGS. 1 and 2.

As shown in FIG. 3, the control / processing unit 200 includes a central computing device (CPU) 210, a fixed disk device (HDD) 220, a main storage device (memory) 230, a user interface 240, an OCT scanner control unit 250, and an OCT scanner. It has (X) driver 251 and OCT scanner (Y) driver 252, SLO scanner control unit 260, SLO scanner (X) driver 261, SLO scanner (Y) driver 262, motor driver 270, and fixation target control unit 280. It is composed of.

The CPU 210 is connected to the display unit 400, the HDD 220, the memory 230, and the user interface 240. Further, the CPU 210 is connected to the OCT scanner control unit 250, the SLO scanner control unit 260, the motor driver 270, the fixation target control unit 280, the photodiode 153, and the line sensor 614.

The CPU 210 controls the OCT scanner control unit 250 that generates the scanning waveform of the OCT scanning means 134. Then, the OCT scanner control unit 250 controls the drive of the OCT scanning means 134 by controlling the OCT scanner (X) driver 251 and the OCT scanner (Y) driver 252 based on the control of the CPU 210.

Further, the CPU 210 controls the SLO scanner control unit 260 that generates the scanning waveform of the SLO scanning means 142. Then, the SLO scanner control unit 260 controls the drive of the SLO scanning means 142 by controlling the SLO scanner (X) driver 261 and the SLO scanner (Y) driver 262 based on the control of the CPU 210. Specifically, the SLO scanner control unit 260 controls the drive of the SLO scanning means 142 via the SLO scanner (X) driver 261 and the SLO scanner (Y) driver 262 to illuminate the fundus Ef of the eye E to be inspected. Scan two-dimensionally with. As a result, the photodiode 153 can acquire the signal of the SLO image, which is a two-dimensional image of the fundus Ef.

Further, the CPU 210 controls the drive of a motor (not shown) that drives the OCT focus lens 135-1, the SLO focus lens 135-4, and the reference mirror 132-3 via the motor driver 270.

Further, the CPU 210 controls the fixation target control unit 280 that controls the light emission of the fixation lamp 151. Then, the fixation target control unit 280 controls the light emission of the fixation lamp 151 based on the control of the CPU 210. Specifically, in the present embodiment, the information of the initial imaging area and the scanning line spacing necessary for acquiring the SLO image at the time of preview is stored in the memory 230 in advance. Then, the fixation target control unit 280 adjusts to the timing at which the SLO scanning means 142 scans a desired position on the fundus Er with light based on the frame rate and the scanning line spacing of the initial imaging region or partial region of the SLO image. The fixation lamp 151 is made to emit light (lights up) to form an arbitrary fixation target at an arbitrary position on the fundus Er.

Further, the CPU 210 controls the photodiode 153 that acquires the SLO image signal, acquires the SLO image signal from the photodiode 153, and performs image processing of the SLO image signal and the like.

Further, the CPU 210 controls the line sensor 614 to acquire the OCT image signal, acquires the OCT image signal from the line sensor 614, and performs image processing of the OCT image signal and the like. Specifically, in the present embodiment, the CPU 210 Fourier transforms the OCT image signal obtained from the line sensor 614 and converts the obtained signal into luminance or density information in the depth direction (Z direction) of the eye E to be inspected. ) Generate a tomographic image. Such a scanning method is called an A scan, and the obtained tomographic image is called an A scan image. By performing this A scan in a predetermined transverse direction of the eye E to be inspected by using the OCT scanning means 134, a plurality of A scan images can be acquired. For example, scanning the OCT scanning means 134 in the X direction gives a tomographic image on the XZ plane, and scanning the OCT scanning means 134 in the Y direction gives a tomographic image on the YZ plane. The method of scanning the eye E to be examined in a predetermined transverse direction in this way is called a B scan, and the obtained tomographic image is called a B scan image.

The memory 230 stores, for example, a program for the CPU 210 to execute a process, various information, and the like in advance, and also stores various information and the like obtained by the process of the CPU 210. For example, the memory 230 stores table information showing the correspondence between the objective lenses 111 and 121 having different magnifications that can be arranged at positions facing the eye E to be inspected and various parameters. Further, the memory 230 also stores the subject information and the like related to the eye E to be examined.

Next, a method of photographing a tomographic image by the ophthalmic apparatus 10 will be described.
By controlling the OCT scanning means 134, the ophthalmic apparatus 10 can take a tomographic image of a predetermined portion of the fundus Ef of the eye E to be inspected.

First, the CPU 210 controls the OCT scanning means 134 to scan the measurement light in the X direction, and acquires an OCT image signal related to a predetermined number of scans from the imaging range in the X direction on the fundus Ef with the line sensor 614. Then, the CPU 210 performs a fast Fourier transform (FFT) on the luminance distribution of the OCT image signal of the line sensor 614 obtained at a certain position in the X direction, and displays the linear luminance distribution obtained by the FFT on the display unit 400. Convert to density or color information to show. In the present embodiment, this corresponds to an A-scan image, and a two-dimensional image in which the plurality of A-scan images are arranged corresponds to a B-scan image. Then, the CPU 210 acquires a plurality of A-scan images for constructing one B-scan image, then moves the scanning position in the Y direction and scans in the X-direction again to obtain the plurality of B-scan images. get. Then, the CPU 210 can be used for the diagnosis of the eye E to be inspected by the examiner by displaying the plurality of B-scan images or the three-dimensional image constructed from the plurality of B-scan images on the display unit 400. Here, an example of acquiring a B-scan image by scanning in the X direction has been described, but the present embodiment is not limited to this, and the B-scan image is obtained by scanning in the Y direction. You may try to get it. Further, an arbitrary scanning pattern may be formed by scanning in both the X direction and the Y direction, and a B scan image may be acquired.

<Control of change of fixation target>
Next, the control of changing the fixation target when the magnification of the objective lens is changed will be described.

FIG. 4 shows an optical path L2 when an objective lens 111 having a low magnification (a short focal length and a wide angle of view) is arranged at a position facing the eye E to be inspected in the ophthalmic apparatus 10 according to the first embodiment of the present invention. It is a figure which shows the position of the SLO optical system and the optometry objective optical system which concerns on. Further, FIG. 5 shows an objective lens 121 having a higher magnification (longer focal length and narrower angle of view) than the objective lens 111 at a position facing the eye E to be inspected in the ophthalmic apparatus 10 according to the first embodiment of the present invention. It is a figure which shows the position of the SLO optical system and the fixation target optical system which concerns on an optical path L2 when it is arranged. In FIGS. 4 and 5, the same reference numerals are given to the configurations similar to those shown in FIG. Further, in FIGS. 4 and 5, the SLO focus lenses 135-4 are arranged at different positions.

In FIG. 4, the working distance WD1 is the distance between the eye to be inspected E and the objective lens 111, which is determined according to the focal length of the low-magnification objective lens 111. Similarly, in FIG. 5, the working distance WD2 is the distance between the eye E to be inspected and the objective lens 121, which is determined according to the focal length of the high-magnification objective lens 121.

In the present embodiment, the SLO optical system and the fixation target optical system related to the optical path L2 shown in FIG. 2 (the same applies to FIGS. 4 and 5) are interposed via an objective lens arranged at a position facing the eye E to be inspected. It constitutes a projection means for projecting a fixation target for fixing the eye E to be examined onto the eye E to be inspected. That is, the projection means in the present embodiment scans the fixation light 151, which is a light emitting means for emitting the fixation light related to the fixation target, and the fixation light from the fixation lamp 151 with respect to the eye E to be inspected. The SLO scanning means 142, which is a scanning means for projecting the fixation target onto the eye E to be inspected, is included.

Then, in the present embodiment, the CPU 210 has a case where the magnification of the objective lens acquired from the objective lens detection unit 131 is changed (for example, the low-magnification objective lens 111 shown in FIG. 4 to the high-magnification objective shown in FIG. 5). When the lens 121 is changed, or when the high-magnification objective lens 121 shown in FIG. 5 is changed to the low-magnification objective lens 111 shown in FIG. 4), the size of the fixation target based on the change in the magnification is used. The above-mentioned projection means is adjusted so that the change in the force is small. At this time, for example, the CPU 210 adjusts the projection means described above so that the size of the fixation target before the magnification is changed and the size of the fixation target after the magnification is changed are the same. Is more preferable.

Further, in the present embodiment, the CPU 210 has a case where the magnification of the objective lens acquired from the objective lens detection unit 131 is changed (for example, the low magnification objective lens 111 shown in FIG. 4 to the high magnification objective shown in FIG. 5). When the lens 121 is changed, or when the high-magnification objective lens 121 shown in FIG. 5 is changed to the low-magnification objective lens 111 shown in FIG. 4), the brightness of the fixation target based on the change in the magnification is used. The above-mentioned projection means is adjusted so that the change in the force is small. At this time, for example, the CPU 210 adjusts the projection means described above so that the brightness of the fixation target before the magnification is changed and the brightness of the fixation target after the magnification is changed are the same. Is more preferable. The CPU 210 that adjusts the brightness of the fixation target constitutes an adjustment means.

Further, in the present embodiment, the table information showing the correspondence between the objective lenses 111 and 121 having different magnifications that can be arranged at positions facing the eye E to be inspected and various parameters related to the control method of the ophthalmic apparatus 10 is provided. It is assumed that it is stored in the memory 230 in advance.

For example, the memory 230 contains table information indicating the correspondence between the objective lenses 111 and 121 having different magnifications that can be arranged at positions facing the eye E to be inspected, the reference position of the SLO focus lens 135-4, and the moving range thereof. , It is assumed that it is stored in advance. Here, the reference position of the SLO focus lens 135-4 is, for example, a position where the SLO focus lens 135-4 is moved after the change when the magnification of the objective lens acquired from the objective lens detection unit 131 is changed. is there. The range of motion of the SLO focus lens 135-4 is, for example, the range of motion (range of motion) of the SLO focus lens 135-4 including the reference position of the SLO focus lens 135-4.

Further, for example, in the memory 230, objective lenses 111 and 121 having different magnifications that can be arranged at positions facing the eye E to be inspected, a reference position of the OCT focus lens 135-1 and its moving range, and a reference mirror 132-3. It is assumed that the table information indicating the correspondence relationship between the reference position and the movement range thereof is stored in advance. Here, the reference position of the OCT focus lens 135-1 is, for example, a position where the OCT focus lens 135-1 is moved after the change when the magnification of the objective lens acquired from the objective lens detection unit 131 is changed. is there. The range of motion of the OCT focus lens 135-1 is, for example, the range of motion (range of motion) of the OCT focus lens 135-1 including the reference position of the OCT focus lens 135-1. The reference position of the reference mirror 132-3 is, for example, a position where the reference mirror 132-3 is moved after the change in the magnification of the objective lens acquired from the objective lens detection unit 131. The moving range of the reference mirror 132-3 is, for example, a movable range (range of motion) of the reference mirror 132-3 including the reference position of the reference mirror 132-3.

<Processing procedure of the control method of the ophthalmic apparatus 10>
FIG. 6 is a flowchart showing an example of a processing procedure in the control method of the ophthalmic apparatus 10 according to the first embodiment of the present invention. In the description of FIG. 6, for the sake of simplicity, the objective lens 111 having a low magnification (wide angle of view) and the objective lens having a high magnification (narrow angle of view) can be arranged at a position facing the eye E to be inspected. ), And the objective lens 121. Further, when starting the flowchart of FIG. 6, the memory 230 stores in advance table information showing the correspondence relationship between the above-mentioned objective lenses 111 and 121 and the reference positions of the SLO focus lenses 135-4 and their moving ranges. It is assumed that Further, when starting the flowchart of FIG. 6, in the memory 230, the reference positions and movement ranges of the objective lenses 111 and 121 and the OCT focus lens 135-1 described above, and the reference positions and movements of the reference mirror 132-3 are stored in the memory 230. It is assumed that the table information indicating the correspondence with the range is stored in advance. Further, at the time of starting the flowchart of FIG. 6, it is assumed that the memory 230 stores in advance table information showing the correspondence between the objective lenses 111 and 121 and the working distances WD1 and WD2.

First, when the objective lens is replaced, in step S1, the objective lens detection unit 131 performs a process of detecting the replaced objective lens. Here, in the present embodiment, the objective lens detection unit 131 detects the attachment / detachment detection marks 112 and 122 provided at different positions of the lens barrel containing the objective lens, thereby detecting the objective lens 111, respectively. And 121 are detected. The replacement of the objective lens is performed by attaching the lens barrel containing the objective lens to the objective lens mounting portion (not shown) of the ophthalmic apparatus 10. At this time, a known mounting mechanism such as a bayonet type can be used as the mounting mechanism of the objective lens mounting portion (not shown).

Subsequently, in step S2, the CPU 210 acquires objective lens information including the magnification of the objective lens from the objective lens detection unit 131. Then, the CPU 210 acquires various parameters corresponding to the objective lens information from the memory 230. The various parameters acquired here include, for example, the working distance (WD1 or WD2) corresponding to the objective lens information, the reference position of the SLO focus lens 135-4 and its moving range, and the reference of the OCT focus lens 135-1. Information including the position and its moving range, and the reference position of the reference mirror 132-3 and its moving range. The CPU 210 that performs the process of step S2 constitutes an acquisition means.

Subsequently, in step S3, the CPU 210 changes the objective lens in step S1 from the low magnification (wide angle of view) objective lens 111 to the high magnification (narrow angle of view) based on the objective lens information acquired in step S2. It is determined whether or not the lens is replaced with the objective lens 121.

As a result of the determination in step S3, when the replacement of the objective lens in step S1 is from the low magnification (wide angle of view) objective lens 111 to the high magnification (narrow angle of view) objective lens 121 (S3 / YES), the process proceeds to step S4.
Proceeding to step S4, the CPU 210 controls to automatically adjust the working distance based on the working distance information acquired in step S2.

On the other hand, as a result of the determination in step S3, when the replacement of the objective lens in step S1 is not the replacement of the low magnification (wide angle of view) objective lens 111 with the high magnification (narrow angle of view) objective lens 121 (S3). / NO), the process proceeds to step S5. That is, when the high-magnification (narrow angle of view) objective lens 121 is replaced with the low-magnification (wide angle of view) objective lens 111, the process proceeds to step S5.
Proceeding to step S5, the CPU 210 does not automatically adjust the working distance, but manually adjusts the working distance based on the operation of the examiner. When the high-magnification (narrow angle of view) objective lens 121 is replaced with the low-magnification (wide angle of view) objective lens 111 and the working distance is changed from the long one to the short one, the inspection unit 100 This is because it moves in the direction toward the subject. That is, in this case, the inspector can move the inspection unit 100 while surely confirming the inspector by performing the manual operation by the inspector.

When the process of step S4 is completed, or when the process of step S5 is completed, the process proceeds to step S6.

Proceeding to step S6, the CPU 210 refers to the SLO focus lens 135-4 according to various parameters related to the SLO focus lens 135-4 corresponding to the objective lens exchanged in step S1 acquired from the memory 230 in step S2. The position (for example, the position of 0D) and its movement range are set. At this time, when the low magnification (wide angle of view) objective lens 111 shown in FIG. 4 is replaced with the high magnification (narrow angle of view) objective lens 121 shown in FIG. 5, the SLO focus lens 135-4 is moved. The possible range and the reference position are set in the optical path L2 in the direction approaching the eye to be inspected E.

Subsequently, in step S7, the CPU 210 controls the movement of the SLO focus lens 135-4 to the position (for example, the reference position) set in step S6.

Subsequently, in step S8, the CPU 210 controls the fixation target control unit 280 and the SLO scanner so that the change in the size of the fixation target based on the change in the magnification of the objective lens acquired from the objective lens detection unit 131 becomes small. The SLO optical system and the fixation target optical system related to the optical path L2, which is a projection means, are adjusted via the unit 260 and the like. At this time, for example, the CPU 210 adjusts the projection means described above so that the size of the fixation target before the magnification is changed and the size of the fixation target after the magnification is changed are the same. Is more preferable. The CPU 210 that adjusts the size of the fixation target constitutes an adjustment means.

Subsequently, in step S9, the CPU 210 controls the fixation target control unit 280 and the SLO scanner so that the change in the brightness of the fixation target based on the change in the magnification of the objective lens acquired from the objective lens detection unit 131 becomes small. The SLO optical system and the fixation target optical system related to the optical path L2, which is a projection means, are adjusted via the unit 260 and the like. At this time, for example, the CPU 210 adjusts the projection means described above so that the brightness of the fixation target before the magnification is changed and the brightness of the fixation target after the magnification is changed are the same. Is more preferable. The CPU 210 that adjusts the brightness of the fixation target constitutes an adjustment means.

Subsequently, in step S10, the CPU 210 performs OCT according to various parameters related to the OCT focus lens 135-1 and the reference mirror 132-3 corresponding to the objective lens exchanged in step S1 acquired from the memory 230 in step S2. The reference position of the focus lens 135-1 and its moving range, and the reference position of the reference mirror 132-3 and its moving range are set. At this time, when the low magnification (wide angle of view) objective lens 111 shown in FIG. 4 is replaced with the high magnification (narrow angle of view) objective lens 121 shown in FIG. 5, these movable ranges and reference positions are used. Is set in the direction away from the eye E to be inspected in the optical path L1 according to the change in the working distance from WD1 to WD2 (WD2-WD1). After that, the CPU 210 controls to move the OCT focus lens 135-1 and the reference mirror 132-3 to the position (for example, the reference position) set in this step.

Subsequently, in step S11, the CPU 210 controls to emit light from the OCT light source 101, acquires an OCT image signal from the line sensor 614, and generates a tomographic image (OCT image) at the fundus Ef of the eye E to be inspected. And perform the acquisition process.

When the process of step S11 is completed, the process of the flowchart of FIG. 6 is completed.

<< Specific processing examples of S8 and S9 in FIG. 6 in this embodiment >>
Next, specific processing examples of steps S8 and S9 of FIG. 6 in the first embodiment will be described.

FIG. 7 shows a first embodiment of the present invention, and is a diagram showing an example of a fixation target when objective lenses having different magnifications are arranged at positions facing the eye E to be inspected. Specifically, FIG. 7A shows a narrow angle of view region 710 in the fundus Er of the eye to be inspected E when the objective lens 121 having a high magnification (narrow angle of view) is arranged at a position facing the eye to be inspected E. It shows the optometry marker 711.

FIG. 7B shows a comparative example in which the objective lens 111 having a low magnification (wide angle of view) is arranged at a position facing the eye E to be inspected, and the size of the fixation target in the present embodiment is adjusted. The wide angle of view region 720 and the fixation target 721 in the fundus Er of the eye E to be inspected are shown. In FIG. 7B, a region corresponding to the narrow angle of view region 710 in FIG. 7A is shown by a dotted line. When the objective lens 111 with a low magnification (wide angle of view) is changed, the fixation target projection control similar to that of the objective lens 121 with a high magnification (narrow angle of view) before the change is performed. ), The fixation target 721 becomes larger for the subject than in the case shown in FIG. 7A.

Therefore, in the present embodiment, in step S8 of FIG. 6, the CPU 210 reduces the change in the size of the fixation target due to the change in the magnification of the objective lens (for example, the size of the fixation target before and after the change). The SLO optical system and the fixation target optical system related to the optical path L2, which is the projection means, are adjusted so that they are the same. FIG. 7C shows the present embodiment, in which the objective lens 111 having a low magnification (wide angle of view) is arranged at a position facing the eye E to be inspected, and the size of the fixation target in the present embodiment. The wide angle-of-view region 720 and the fixation target 722 in the fundus Er of the eye E to be inspected when the adjustment is performed are shown. In FIG. 7 (c), the same reference numerals are given to the same configurations as those in FIG. 7 (b).

Specifically, in the present embodiment, the CPU 210 adjusts the size of the fixation target described above by changing the emission timing of the fixation light by the fixation lamp 151. More specifically, the CPU 210 sets the SLO scanning means as the emission timing of the fixation light by the fixation lamp 151 when the magnification of the objective lens is changed from a high magnification (narrow angle of view) to a low magnification (wide angle of view). The size of the fixation target shown in FIG. 7C is adjusted by making a change to shorten the emission time of the fixation light when the scanning speed by 142 is constant.

FIG. 8 shows a first embodiment of the present invention, and is a diagram showing an example of a fixation target when objective lenses having different magnifications are arranged at positions facing the eye E to be inspected. Specifically, FIG. 8A shows a fixation target in the fundus Er of the eye E to be inspected when the objective lens 121 having a high magnification (narrow angle of view) is arranged at a position facing the eye E to be inspected. There is. Further, FIG. 8B shows a fixation target in the fundus Er of the eye to be inspected E when the objective lens 111 having a low magnification (wide angle of view) is arranged at a position facing the eye to be inspected E. In FIG. 8, the horizontal direction indicates the main scanning direction by the SLO scanning means 142, and the vertical direction indicates the sub-scanning direction by the SLO scanning means 142.

As shown in FIG. 8 (b), when the magnification of the objective lens is changed from a high magnification (narrow angle of view) to a low magnification (wide angle of view), it is covered as compared with the case shown in FIG. 8 (a). The scanning line spacing of the fixation target presented to the examiner becomes wider. That is, as shown in FIG. 8 (b), when the magnification of the objective lens is changed from a high magnification (narrow angle of view) to a low magnification (wide angle of view), as compared with the case shown in FIG. 8 (a). The number of sub-scanning lines for drawing the fixation target (in FIG. 8, the distance between the sub-scanning lines is indicated by i) is reduced. Therefore, when the magnification of the objective lens is changed from a high magnification (narrow angle of view) to a low magnification (wide angle of view), the brightness of the fixation target projected on the eye E to be inspected becomes dark.

Therefore, in the present embodiment, in step S9 of FIG. 6, the CPU 210 reduces the change in the brightness of the fixation target due to the change in the magnification of the objective lens (for example, the brightness of the fixation target before and after the change). The SLO optical system and the fixation target optical system related to the optical path L2, which is the projection means, are adjusted so that they are the same.

For example, the CPU 210 adjusts the brightness of the fixation target described above by changing the emission intensity (emission light amount) of the fixation light by the fixation lamp 151. In this case, in more detail, the CPU 210 increases the emission intensity of the fixation light by the fixation lamp 151 when the magnification of the objective lens is changed from a high magnification (narrow angle of view) to a low magnification (wide angle of view). By making the above-mentioned changes, the brightness of the fixation target described above is adjusted. On the contrary, when the magnification of the objective lens is changed from a low magnification (wide angle of view) to a high magnification (narrow angle of view), the CPU 210 determines the emission intensity (emission light amount) of the fixation light by the fixation lamp 151. By making a change to make it smaller, the above-mentioned adjustment regarding the brightness of the fixation target is performed.

In this embodiment, the embodiment is not limited to the mode in which the brightness of the fixation target is adjusted by changing the emission intensity of the fixation light described above, and other aspects shown below can also be applied. For example, the CPU 210 controls so that the scanning interval of the fixation light (for example, the interval i shown in FIG. 8) with respect to the fundus Ef of the eye E to be inspected by the SLO scanning means 142 becomes substantially the same before and after the change in the magnification of the objective lens. By doing so, it is an aspect of adjusting the brightness of the above-mentioned fixation target.

In the example shown in FIG. 6, both the adjustment related to the size of the fixation target (S8) and the adjustment related to the brightness of the fixation target (S9) are performed. Is not limited to this aspect. For example, an aspect in which only one of the adjustment related to the size of the fixation target (S8) and the adjustment related to the brightness of the fixation target (S9) is performed is also applicable to the present invention. At this time, as in the example shown in FIG. 6, if both the adjustment related to the size of the fixation target (S8) and the adjustment related to the brightness of the fixation target (S9) are performed, either one is adjusted. It is possible to stabilize the fixation of the eye E to be inspected before and after the magnification change as compared with the case where only the adjustment of is performed.

Further, in the above-described example, an embodiment in which the size and brightness of the fixation target are adjusted to be the same before and after scaling is shown, but the present invention is not limited to this embodiment. For example, an aspect of adjusting so that the change in the size and brightness of the fixation target becomes small before and after scaling is also applicable to the present invention.

In the first embodiment, the CPU 210 is an optical path that is a projection means so that when the magnification of the objective lens is changed, the change in the size and / or brightness of the fixation target based on the change in the magnification is small. The SLO optical system and the fixation target optical system related to L2 are adjusted.
According to such a configuration, when the examination is performed by scaling the eye E to be inspected, it is possible to stabilize the fixation of the eye E to be inspected before and after the scaling.

(Second Embodiment)
Next, a second embodiment of the present invention will be described. In the following description of the second embodiment, the description of the same contents as those of the above-mentioned first embodiment will be omitted, and the parts different from the contents of the above-mentioned first embodiment will be described.

The overall configuration of the ophthalmic apparatus 10 according to the second embodiment is the same as the overall configuration of the ophthalmic apparatus 10 according to the first embodiment shown in FIG.

FIG. 9 is a diagram showing a second embodiment of the present invention and showing an example of the internal configuration of the inspection unit 100 and the base unit 600 shown in FIG. Here, in FIG. 9, the inspection unit 100 in the second embodiment is described as “inspection unit 100-2”. In FIG. 9, the same reference numerals are given to the configurations similar to those shown in FIG. 2, and detailed description thereof will be omitted. Specifically, in the second embodiment, the configuration of the optical path L2 is different from that in the first embodiment.

In FIG. 9, the optical path L2-1 is an optical path of the SLO optical system, and the dichroic mirror 170 is removed from the SLO optical system and the fixation target optical system related to the optical path L2 shown in FIG. 2 except for the fixation lamp 151. This is the optical path of the added optical system.

Then, in FIG. 9, an optical path L2-2 of the fixation target optical system is provided independently of the optical path L2-1 of the SLO optical system. As shown in FIG. 9, the optical path L2-2 of the fixation target optical system is provided with a dichroic mirror 170, lenses 171 and 172, a lens unit 180, and a fixation target unit 190. Then, in the present embodiment, the fixation target optical system according to the optical path L2-2 shown in FIG. 9 is for fixing the subject E through an objective lens arranged at a position facing the subject E. It constitutes a projection means for projecting the fixation target onto the eye E to be inspected.

The dichroic mirror 170 is provided between the relay lens 141 and the SLO scanning means 142, and divides the light from the SLO light source 152 and the fixation light from the fixation target unit 190 for each wavelength band. At this time, for example, the transmitted optical path of the dichroic mirror 170 is the optical path L2-1 of the SLO optical system that acquires a two-dimensional image of the eye E to be inspected, and the reflected optical path of the dichroic mirror 170 is the optical path L2 of the fixation target optical system. -2.

The fixation target unit 190 includes a fixation target aperture 191 and an aperture switching means 192, and a fixation lamp 193. Further, the fixation target unit 190 is connected to the fixation target unit driving means 173 configured to be controllable by the CPU 210.

The fixation lamp 193 is, for example, a two-dimensional projection optical system including an LED or the like that generates visible light. The aperture switching means 192 is, for example, a stepping motor, and switches the aperture to be inserted in the optical path L2-2.

The fixation target unit driving means 173 is formed of, for example, a stepping motor. The fixation target unit driving means 173 moves the fixation target unit 190 including the fixation target aperture 191 and the fixation lamp 193 in a two-dimensional direction in a plane orthogonal to the optical path L2-2. It is controlled when moving the position of the fixation target presented to the subject.

The focus lens 171 is driven by, for example, a motor (not shown) for focusing the fixation light by the fixation lamp 193. In this embodiment, the lens unit 180 is not inserted in the optical path L2-2.

The fixation light emitted from the fixation lamp 193 passes through the fixation target aperture 191, the lens 172, and the focus lens 171, is reflected by the dichroic mirror 170, and joins the optical path toward the eye E to be inspected. Since the other configurations of the inspection unit 100-2 shown in FIG. 9 are the same as the configurations of the inspection unit 100-1 in the first embodiment shown in FIG. 2, the description thereof will be omitted.

FIG. 10 shows a second embodiment of the present invention, and is a diagram showing an example of a schematic configuration of the fixation target aperture 191 shown in FIG. The fixation target aperture 191 shown in FIG. 10 is a view seen from the fixation lamp 193 side.

The fixation target aperture 191 is provided between the fixation lamp 193 and the objective lens as shown in FIG. 9, and allows the fixation light from the fixation lamp 193 to pass through and has a different size as shown in FIG. It is a drawing means in which a plurality of openings 1001 and 1002 are formed.

Specifically, the opening 1001 of the fixation target aperture 191 is an aperture that is inserted into the optical path L2-2 when the high-magnification (narrow angle of view) objective lens 121 is arranged at a position facing the eye E to be inspected. Is. Further, the opening 1002 of the fixation target aperture 191 is an aperture that is inserted into the optical path L2-2 when the low-magnification (wide angle of view) objective lens 111 is arranged at a position facing the eye E to be inspected. ..

When the magnification is changed by changing the objective lens, the size of the fixation target projected on the fundus Er of the subject changes. Specifically, when the aperture related to the opening 1001 for high magnification (narrow angle of view) is inserted in the optical path L2-2 and the objective lens 111 is changed to a low magnification (wide angle of view) objective lens 111. As described with reference to FIG. 7, the size of the fixation target projected on the eye E to be inspected becomes large. Therefore, in this embodiment, in this case, by switching to the aperture related to the opening 1002 having a low magnification (wide angle of view), the eye E to be inspected is presented with an fixation target having a size that does not depend on the change in the magnification.

As a specific process of the present embodiment, the CPU 210 changes the opening of the fixation target aperture 191 when the magnification of the objective lens is changed, so that the size of the fixation target in step S8 of FIG. 6 is changed. Make adjustments related to this. More specifically, when the magnification of the objective lens is changed from a high magnification to a low magnification, the CPU 210 reduces the change in the size of the fixation target based on the change in the magnification (for example, before and after the change). Change to a smaller opening 1002 (so that the objectives have the same size).

However, when the aperture related to the opening 1002 is used, the light-shielding area of the fixation light increases as compared with the case where the aperture related to the opening 1001 is used, so that the fixation target projected on the eye E to be inspected is used. The brightness becomes dark. Therefore, in the present embodiment, when the magnification of the objective lens is changed from a high magnification (narrow angle of view) to a low magnification (wide angle of view), the CPU 210 emits light emission intensity (emission light amount) of the fixation light by the fixation lamp 193. ) Is increased to adjust the brightness of the fixation target described above. On the contrary, when the magnification of the objective lens is changed from a low magnification (wide angle of view) to a high magnification (narrow angle of view), the CPU 210 determines the emission intensity (emission light amount) of the fixation light by the fixation lamp 193. By making a change to make it smaller, the above-mentioned adjustment regarding the brightness of the fixation target is performed.

In addition, in FIG. 10, an example of providing circular apertures relating to two openings 1001 and 1002 for high magnification (narrow angle of view) and low magnification (wide angle of view) is shown, but in this embodiment, this aspect is shown. It is not limited to. For example, a mode in which a plurality of other apertures for scaling and a plurality of apertures having various shapes are provided is also applicable to the present embodiment.

Further, in the above-described example, the mode of adjusting both the adjustment related to the size of the fixation target and the adjustment related to the brightness of the fixation target is shown, but the present invention is limited to this mode. It's not a thing. For example, an aspect in which only one of the adjustment related to the size of the fixation target and the adjustment related to the brightness of the fixation target is adjusted is also applicable to the present invention. At this time, if both the adjustment related to the size of the optometry and the adjustment related to the brightness of the optometry are performed, the image is covered before and after the scaling as compared with the case where only one of the adjustments is made. It has the effect of making the fixation of the optometry E more stable.

Further, in the above-described example, an embodiment in which the size and brightness of the fixation target are adjusted to be the same before and after scaling is shown, but the present invention is not limited to this embodiment. For example, an aspect of adjusting so that the change in the size and brightness of the fixation target becomes small before and after scaling is also applicable to the present invention.

In the second embodiment, the CPU 210 is a projection means so that when the magnification of the objective lens is changed, the change in the size and / or brightness of the fixation target based on the change in the magnification is small. The fixation target optical system related to the optical path L2-2 of No. 9 is adjusted.
According to such a configuration, when the examination is performed by scaling the eye E to be inspected, it is possible to stabilize the fixation of the eye E to be inspected before and after the scaling.

(Third Embodiment)
Next, a third embodiment of the present invention will be described. In the following description of the third embodiment, the description of the same contents as those of the first and second embodiments described above will be omitted, and the parts different from the contents of the first and second embodiments described above will be omitted. Will be explained.

The overall configuration of the ophthalmic apparatus 10 according to the third embodiment is the same as the overall configuration of the ophthalmic apparatus 10 according to the first embodiment shown in FIG. Further, the internal configuration of the inspection unit 100 in the third embodiment is basically the same as the internal configuration of the inspection unit 100-2 in the second embodiment shown in FIG. 9, but relates to the optical path L2-2. Some configurations of the fixation target optical system are different.

FIG. 11 shows a third embodiment of the present invention, and is a diagram showing an example of an fixation target optical system related to an optical path L2-2 of the inspection unit 100-2 shown in FIG. In FIG. 11, the same reference numerals are given to the configurations similar to those shown in FIG. 9, and detailed description thereof will be omitted.

As shown in FIG. 11, the fixation target optical system according to the optical path L2-2 in the third embodiment is provided with a dichroic mirror 170, lenses 171 and 172, a lens unit 180, and a fixation lamp 194.

The fixation lamp 194 is a two-dimensional light emitting means such as a display panel, and is formed of, for example, a liquid crystal panel or an organic EL panel that generates visible light. The fixation light emitted from the fixation lamp 194 passes through the lens 172 and the focus lens 171, is reflected by the dichroic mirror 170, and joins the optical path toward the eye E to be inspected.

The lens unit 180 is a magnification-changing means provided between the fixation lamp 194 and the objective lens to change the magnification of the fixation target projected on the eye E to be inspected. Specifically, in the present embodiment, the eye to be inspected. It has a function of increasing the magnification of the fixation target projected on E. The lens unit 180 includes a lens 181 and a lens 182. The lens unit 180 has a function of canceling the effect of the change in the magnification when the magnification of the objective lens is changed. Specifically, in the present embodiment, when the low magnification (wide angle of view) objective lens 111 is arranged at a position facing the eye E to be inspected, the lens unit 180 is not inserted into the optical path L2-2. The fixation target is set so as to be optimally projected on the eye E to be inspected. Further, when the objective lens 121 having a high magnification (narrow angle of view) is arranged at a position facing the eye E to be inspected, the fixation target is the eye to be inspected with the lens unit 180 inserted in the optical path L2-2. It is set to be optimally projected on E (to magnify the fixation target). The insertion / evacuation of the lens unit 180 into the optical path L2-2 is performed by a lens unit driving means (for example, a stepping motor) which is controllable by the CPU 210 and is not shown.

Since the other configurations of the inspection unit 100 in the third embodiment are the same as the configurations of the inspection unit 100-2 in the second embodiment shown in FIG. 9, the description thereof will be omitted.

As a specific process of the present embodiment, the CPU 210 inserts / retracts the lens unit 180, which is a scaling means, with respect to the optical path L2-2 when the magnification of the objective lens is changed. The size of the fixation target in step S8 of the above is adjusted. More specifically, when the magnification of the objective lens is changed from a high magnification (narrow angle of view) to a low magnification (wide angle of view), the CPU 210 is projected onto the eye E to be inspected from the viewpoint described with reference to FIG. In order to reduce the fixation target, the lens unit 180 is controlled to be retracted from the optical path L2-2. Further, when the magnification of the objective lens is changed from a low magnification (wide angle of view) to a high magnification (narrow angle of view), the CPU 210 fixes the image projected onto the eye E to be inspected from the viewpoint described with reference to FIG. Control is performed to insert the lens unit 180 into the optical path L2-2 in order to enlarge the target.

In the third embodiment, the CPU 210 is the optical path L2-of FIG. 11, which is a projection means so that when the magnification of the objective lens is changed, the change in the size of the fixation target based on the change in the magnification is small. The fixation target optical system according to No. 2 is adjusted.
According to such a configuration, when the examination is performed by scaling the eye E to be inspected, it is possible to stabilize the fixation of the eye E to be inspected before and after the scaling. Further, in the third embodiment, since the lens unit 180 is inserted / retracted with respect to the optical path L2-2 in order to cancel the action of changing the magnification of the objective lens, the brightness of the fixation target before and after the change of the magnification of the objective lens It can be considered that it does not change. As a result, in the third embodiment, it is not necessary to adjust the emission intensity (emission light amount) of the fixation lamp 194, which is related to the brightness of the fixation light, and the processing can be reduced.

In the third embodiment as well, as in the first and second embodiments described above, it is assumed that the size of the fixation target is adjusted to be the same before and after the scaling. , The present invention is not limited to this aspect. For example, an aspect of adjusting so that the change in the size of the fixation target becomes small before and after scaling is also applicable to the present invention.

Further, in the example shown in FIG. 11 (also in FIG. 9), a mode in which one lens unit 180 is provided as the scaling means is shown, but the present invention is not limited to this mode. For example, when there are a plurality of magnifications related to magnification and there are a plurality of objective lenses corresponding to these magnifications, a plurality of lens units corresponding to each magnification are prepared, and these lens units are switched according to the magnification related to the magnification. You may do so. Further, the variable magnification may be canceled by moving the distance between the lenses inside the lens unit 180 or the position of the optical axis of the lens unit 180 itself.

(Fourth Embodiment)
Next, a fourth embodiment of the present invention will be described. In the following description of the fourth embodiment, the description of the same contents as those of the above-mentioned first to third embodiments is omitted, and the parts different from the contents of the above-mentioned first to third embodiments are omitted. Will be explained.

The overall configuration of the ophthalmic apparatus 10 according to the fourth embodiment is the same as the overall configuration of the ophthalmic apparatus 10 according to the first embodiment shown in FIG. Further, the internal configuration of the inspection unit 100 in the fourth embodiment is basically the same as the internal configuration of the inspection unit 100-2 in the second embodiment shown in FIG. 9, but relates to the optical path L2-2. Some configurations of the fixation target optical system are different. Specifically, the configuration of the fixation target optical system according to the optical path L2-2 in the fourth embodiment is the same as the configuration of the fixation target optical system according to the optical path L2-2 in the third embodiment shown in FIG. Is.

FIG. 12 shows a fourth embodiment of the present invention, and is a diagram showing an example of a light emitting pattern of the fixation lamp 194 shown in FIG. Specifically, FIG. 12A shows an example of the light emission pattern 1201 of the fixation lamp 194 when the objective lens 121 having a high magnification (narrow angle of view) is arranged at a position facing the eye E to be inspected. .. Further, FIG. 12B shows an example of the light emission pattern 1202 of the fixation lamp 194 when the low magnification (wide angle of view) objective lens 111 is arranged at a position facing the eye E to be inspected.

As described above, when the magnification is changed by changing the objective lens, the size of the fixation target projected on the fundus Er of the subject changes. Specifically, when the objective lens 111 is changed to a low magnification (wide angle of view) objective lens 111 while emitting light with the light emission pattern 1201 for high magnification (narrow angle of view), as described with reference to FIG. In addition, the size of the fixation target projected on the eye E to be inspected becomes large. Therefore, in this embodiment, in this case, the light emitting pattern of the fixation lamp 194 is changed to the light emitting pattern 1202 for low magnification (wide angle of view), which has a smaller light emitting region than the light emitting pattern 1201, so that the eye E is examined. A fixed angle of view of a size that does not depend on the change in magnification is presented.

As a specific process of the present embodiment, when the magnification of the objective lens is changed, the CPU 210 changes the light emitting pattern of the fixation lamp 194 to change the light emitting region, so that the solidification in step S8 of FIG. 6 is performed. Make adjustments related to the size of the optotype. More specifically, when the magnification of the objective lens is changed from a high magnification to a low magnification, the CPU 210 reduces the change in the size of the fixation target based on the change in the magnification (for example, before and after the change). The light emitting pattern 1202 is changed so that the light emitting region becomes smaller (so that the size of the optotype is the same).

However, when the light emitting pattern 1202 is used, the light emitting area is reduced as compared with the case where the light emitting pattern 1201 is used, so that the brightness of the fixation target projected on the eye E to be inspected becomes dark. Therefore, in the present embodiment, when the magnification of the objective lens is changed from a high magnification (narrow angle of view) to a low magnification (wide angle of view), the CPU 210 emits light emission intensity (emission light amount) of the fixation light by the fixation lamp 194. ) Is increased to adjust the brightness of the fixation target in step S9 of FIG. On the contrary, when the magnification of the objective lens is changed from a low magnification (wide angle of view) to a high magnification (narrow angle of view), the CPU 210 determines the emission intensity (emission light amount) of the fixation light by the fixation lamp 194. By making a change to make it smaller, the brightness of the fixation target in step S8 of FIG. 6 is adjusted.

Note that FIG. 12 shows an example in which two light emission patterns 1201 and 1202 for high magnification (narrow angle of view) and low magnification (wide angle of view) are prepared, but the present embodiment is limited to this mode. It's not something. For example, a mode in which a plurality of other light emitting patterns for variable magnification or a plurality of light emitting patterns having various shapes are prepared is also applicable to the present embodiment.

Further, in the above-described example, the mode of adjusting both the adjustment related to the size of the fixation target and the adjustment related to the brightness of the fixation target is shown, but the present invention is limited to this mode. It's not a thing. For example, an aspect in which only one of the adjustment related to the size of the fixation target and the adjustment related to the brightness of the fixation target is adjusted is also applicable to the present invention. At this time, if both the adjustment related to the size of the optometry and the adjustment related to the brightness of the optometry are performed, the image is covered before and after the scaling as compared with the case where only one of the adjustments is made. It has the effect of making the fixation of the optometry E more stable.

Further, in the above-described example, an embodiment in which the size and brightness of the fixation target are adjusted to be the same before and after scaling is shown, but the present invention is not limited to this embodiment. For example, an aspect of adjusting so that the change in the size and brightness of the fixation target becomes small before and after scaling is also applicable to the present invention.

In the fourth embodiment, the CPU 210 is a projection means so that when the magnification of the objective lens is changed, the change in the size and / or brightness of the fixation target based on the change in the magnification is small. The fixation target optical system related to the optical path L2-2 of No. 11 is adjusted.
According to such a configuration, when the examination is performed by scaling the eye E to be inspected, it is possible to stabilize the fixation of the eye E to be inspected before and after the scaling.

(Other embodiments)
The present invention supplies a program that realizes one or more functions of the above-described embodiment to a system or device via a network or storage medium, and one or more processors in the computer of the system or device reads and executes the program. It is also possible to realize the processing. It can also be realized by a circuit (for example, ASIC) that realizes one or more functions.
This program and a computer-readable storage medium that stores the program are included in the present invention.

It should be noted that the above-described embodiments of the present invention merely show examples of embodiment in carrying out the present invention, and the technical scope of the present invention should not be construed in a limited manner by these. Is. That is, the present invention can be implemented in various forms without departing from the technical idea or its main features.

10: Ophthalmic apparatus, 100: Examination unit, 200: Control / processing unit, 300: Input unit, 400: Display unit, 500: Stage unit, 600: Base unit, 700: Face receiving unit

Claims (18)

It is a projection means for projecting a fixation target for fixing the eye to be inspected onto the eye to be inspected through an objective lens arranged at a position facing the eye to be inspected, and the fixation light according to the fixation target. A projection means including a light emitting means for emitting light and a scanning means for scanning the fixation light with respect to the eye to be inspected.
When the magnification of the objective lens is changed, the scanning interval of the fixation light with respect to the eye to be inspected by the scanning means is such that the change in the scanning interval of the fixation light based on the change in the magnification becomes small. to an adjustment means for adjusting the said projection means according to the scanning interval of the fixation light,
An ophthalmic device characterized by having. It is a projection means for projecting a fixation target for fixing the eye to be inspected onto the eye to be inspected through an objective lens arranged at a position facing the eye to be inspected, and the fixation light according to the fixation target. A projection means including a light emitting means for emitting light and a scanning means for scanning the fixation light with respect to the eye to be inspected.
The scanning interval of the fixation light with respect to the eye to be inspected by the scanning means in response to the change in the magnification corresponding to the change in the angle of view in the optical system for photographing the eye to be inspected. The adjusting means for adjusting the projection means related to the scanning interval of the fixation light so that the change in the scanning interval of the fixation light based on the above is small.
An ophthalmic device characterized by having. The adjusting means adjusts the projection means related to the size of the fixation target so that the change in the size of the fixation target due to the change in the magnification becomes small when the magnification is changed. The ophthalmic apparatus according to claim 1 or 2, further comprising. The adjusting means adjusts the size of the fixation target so that the size of the fixation target before the magnification is changed and the size of the fixation target after the magnification is changed are the same. The ophthalmic apparatus according to claim 3 , wherein the projection means is adjusted. The ophthalmic apparatus according to claim 3 or 4 , wherein the adjusting means adjusts the projection means according to the size of the fixation target by changing the emission timing of the fixation light. The adjusting means, if the previous Kibai rate is changed from a high magnification to a low magnification, as a light emitting timing of the fixation light, short emission time of the fixation light when a constant speed of the scanning The ophthalmic apparatus according to claim 5 , wherein the projection means related to the size of the fixation target is adjusted by making such a change. The adjusting means, if the previous Kibai rate is changed, so that the change in the brightness of the fixation target based on the change of the magnification is reduced, the projection means according to the brightness of the fixation target The ophthalmic apparatus according to any one of claims 1 to 6 , wherein the adjustment is further performed. The adjusting means adjusts the brightness of the fixation target so that the brightness of the fixation target before the magnification is changed and the brightness of the fixation target after the magnification is changed are the same. The ophthalmic apparatus according to claim 7 , wherein the projection means is adjusted. The ophthalmic apparatus according to claim 7 or 8 , wherein the adjusting means adjusts the projection means related to the brightness of the fixation target by changing the emission intensity of the fixation light. The adjusting means, if the previous Kibai rate is changed from a high magnification to a low magnification, by making changes to increase the emission intensity of the fixation light, the projection means according to the brightness of the fixation target The ophthalmic apparatus according to claim 9 , wherein the adjustment is performed. It said adjusting means, before and after the change before Kibai rate, by scanning interval of the fixation light is controlled to be substantially the same, performing the adjustment of the projection means in accordance with the scanning interval of the fixation light The ophthalmic apparatus according to any one of claims 1 to 10. The adjusting means, if the previous Kibai rate is changed from a high magnification to a low magnification, the as scanning interval fixation light is narrowed, the adjustment of the projection unit in accordance with the scanning interval of the fixation light The ophthalmic apparatus according to any one of claims 1 to 11 , wherein the ophthalmic apparatus according to any one of claims 1 to 11. The ophthalmic apparatus according to any one of claims 1 to 12 , wherein the scanning interval is a scanning interval in the sub-scanning direction by the scanning means. And the SLO optical system for scanning in the subject's eye by the scanning means the illumination light emitted from different SLO light source from the previous SL-emitting means,
A fixation target control means that controls the light emission of the light emitting means according to the timing at which the illumination light is scanned by the scanning means in the eye to be inspected.
With more
The ophthalmic apparatus according to any one of claims 1 to 13 , wherein the projection means and the SLO optical system share a part of optical members including the scanning means. The ophthalmic apparatus
A plurality of objective lenses having different magnifications are interchangeably configured as the objective lens arranged at a position facing the eye to be inspected.
The ophthalmic apparatus according to any one of claims 1 to 14 , further comprising an acquisition means for acquiring the magnification of the objective lens arranged at a position facing the eye to be inspected. It is a projection means for projecting a fixation target for fixing the eye to be inspected onto the eye to be inspected through an objective lens arranged at a position facing the eye to be inspected, and is a fixation light related to the fixation target. A method for controlling an ophthalmic apparatus having a projection means including a light emitting means for emitting light and a scanning means for scanning the fixation light with respect to the eye to be inspected.
When the magnification of the objective lens is changed, the scanning interval of the fixation light with respect to the eye to be inspected by the scanning means is such that the change in the scanning interval of the fixation light based on the change in the magnification becomes small. a control method for an ophthalmologic apparatus characterized by having an adjustment step of adjusting the said projection means according to the scanning interval of the fixation light. It is a projection means for projecting a fixation target for fixing the eye to be inspected onto the eye to be inspected through an objective lens arranged at a position facing the eye to be inspected, and the fixation light according to the fixation target. A method for controlling an ophthalmic apparatus having a projection means including a light emitting means for emitting light and a scanning means for scanning the fixation light with respect to the eye to be inspected.
The scanning interval of the fixation light with respect to the eye to be inspected by the scanning means in response to the change in the magnification corresponding to the change in the angle of view in the optical system for photographing the eye to be inspected. An adjustment step of adjusting the projection means related to the scanning interval of the fixation light so that the change in the scanning interval of the fixation light based on the above is small.
A method for controlling an ophthalmic apparatus, which comprises. A program that causes a computer to execute the control method of the ophthalmic apparatus according to claim 16 or 17.

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