JP6847396B2 - Skin cosmetics - Google Patents

Description

The present invention relates to an external preparation for skin, and more specifically, to a skin cosmetic that gives a fresh feeling of use at the time of application and improves the adhesion of the aqueous make-up cosmetic to the skin and the long-lasting makeup.

Traditionally, make-up cosmetics have been used for the purpose of creating beautiful skin, impressive eyes and mouth with color and shading. In order to maximize the cosmetic effect, it is important to form a uniform and beautiful cosmetic film on the skin. Aqueous makeup cosmetics such as dispersion-type water-based cosmetics in which powder is dispersed in water and oil-in-water emulsified cosmetics containing powder are cosmetics that have a fresh and smooth feel and are less burdensome to the skin. It is popular as a dosage form, especially among the younger generation.

However, while water-based make-up cosmetics are excellent in fresh and smooth feel, they are inferior in adhesion to the skin compared to oil-based make-up cosmetics and water-in-oil type make-up cosmetics, and the adhesiveness of the cosmetic film and makeup It was a formulation that was difficult to hold.

In view of such circumstances, water-based make-up cosmetics have been proposed for the purpose of improving adhesion to the skin, adhesion of the makeup film, and long-lasting makeup. For example, Patent Document 1 proposes an aqueous make-up cosmetic containing glycosyltrehalose, polyacrylate, and powder.

Japanese Unexamined Patent Publication No. 2008-273943

However, the water-based make-up cosmetics described in Patent Document 1 have improved the makeup retention to some extent, but the adhesiveness of the makeup film is insufficient. Although various other proposals have been made, it has been difficult to achieve skin adhesion, makeup film adhesion, and makeup retention that surpass those of oil-based makeup cosmetics with water-based makeup cosmetics.

An object of the present invention is to provide a skin cosmetic that gives a fresh feeling of use at the time of application and improves the adhesion of the water-based makeup cosmetic to the skin and the longevity of the makeup.

In order to solve the above problems, the present inventor pays attention to the makeup base, not the water-based makeup cosmetic itself, and acts as a binder to make the water-based makeup cosmetic adhere to the skin and retain the makeup. I thought it might be possible to improve. As a result of diligent studies by the present inventor, it has been found that a skin cosmetic in which two kinds of alkylene oxide derivatives, a water-soluble thickener, and water are combined in a specific ratio can solve the above problems completely, and the present invention has been found. Has been completed.

That is, the present invention contains the following component (a) in an amount of 0.1 to 25% by mass, the component (b) in an amount of 0.01 to 4 % by mass, and the component (c) in an amount of 0.01 to 5% by mass. The present invention relates to a skin cosmetic, characterized in that the mass ratio ((b) / (a)) of the component (a) to the component (a) is 1/200 to 1/6.

(A): A polyalkylene oxide derivative represented by the following formula (1).

Z- [O (A ¹ O) _m (EO) _n- R ¹ ] p ... (1)

(In equation (1),
Z is a residue obtained by removing all hydroxyl groups from an alcohol having 1 to 6 carbon atoms.
p is the valence of the alcohol, which is 1 or more and 6 or less.
R ¹ is an alkyl group having 1 to 4 carbon atoms.
A ¹ O is an oxyalkylene group having 3 to 4 carbon atoms.
EO is an oxyethylene group
Wherein the average addition molar number p × m of the oxyalkylene group A ^{1 O} has to satisfy 1 ≦ p × m ≦ 70 in derivatives,
The average number of moles p × n added to the oxyethylene group EO in the derivative satisfies 1 ≦ p × n ≦ 70.
The oxyalkylene group A ^{1 O} ratio average addition mole number and an average addition mole number of the oxyethylene group EO to the total of the average molar number of addition of the oxyethylene group EO of n / (m + n) is from 0.15 to 0 It is .75. )

(B) An alkylene oxide derivative represented by the following formula (2)

R ² O-[(A ² O) _x (EO) _y ] -H ... (2)

(In equation (2),
R ² is an alkyl group having 1 to 4 carbon atoms.
A ² O is an oxyalkylene group having 3 carbon atoms.
EO is an oxyethylene group
x is an average addition number of moles of the oxyalkylene groups A ^{2 O,}
Satisfying 1 ≦ x ≦ 40
y is the average number of moles of the oxyethylene group added, satisfying 3 ≦ y ≦ 60.
The oxyalkylene group ^{A 2} the O average addition mole number of the to the total of the average molar number of addition of the oxyethylene group EO an oxyethylene group ratio of EO x / (x + y) is from 0.35 to 0.85,
The oxyalkylene group A ² O and the oxyethylene group EO are randomly added. )

(C) Water-soluble thickener (d) Water

According to the skin cosmetic of the present invention, a fresh feeling of use is obtained at the time of application, and the adhesion of the water-based makeup cosmetic to the skin and the long-lasting makeup are improved.

Hereinafter, the present invention will be described in detail.
The skin cosmetic of the present invention contains the following components (a) to (d).
[Component (a)]
In the polyalkylene oxide derivative represented by the general formula (1) in the present invention, Z is a residue obtained by removing a hydroxyl group from an alcohol (Z (OH) p) having 1 to 6 carbon atoms, and p is the valence of the alcohol. Shown are 1-6.

When the number of carbon atoms of the alcohol (Z (OH) p) exceeds 6, the freshness at the time of application is impaired, so the number is set to 6 or less, but the following is more preferable. Further, when the number of carbon atoms of the alcohol (Z (OH) p) is zero, that is, when it is a hydrogen atom, the adhesiveness of the aqueous make-up and the long-lasting make-up are lowered, so the value is set to 1 or more. Further, when the valence p of the alcohol (Z (OH) p) exceeds 6, the adhesiveness of the aqueous make-up and the long-lasting makeup are lowered, so the value is 6 or less, but more preferably 3 or less.

Specifically, the alcohol (Z (OH) p) is methanol, ethanol, n-propanol, isopropanol, n-butanol, sec-butanol, tert-butanol, pentanol, hexanol, ethylene glycol, propylene glycol, butylene. Alcohols such as glycol, pentylene glycol, hexylene glycol, glycerin, erythritol, pentaerythritol, xylitol, trimethylolpropane, and sorbitol are shown. The alcohol (Z (OH) p) is preferably a residue of methanol, ethanol, ethylene glycol, propylene glycol, or glycerin, and more preferably methanol, ethylene glycol, or propylene glycol.

A ¹ O is an oxyalkylene group having 3 to 4 carbon atoms, and specific examples thereof include an oxypropylene group, an oxybutylene group, an oxytrimethylene group, and an oxytetramethylene group. It is preferably an oxypropylene group or an oxybutylene group, and more preferably an oxypropylene group.

m is the average addition number of moles of A ^{1 O} per hydroxyl group of said alcohol. Average addition number of moles of ^{A 1} O as a whole component (a) "p × m" is 1 to 70, preferably 3 to 50, more preferably 5 to 40. If "p × m" exceeds 70, the freshness at the time of application is impaired, and if it is less than 1, the adhesiveness of the water-based make-up and the long-lasting makeup are reduced.

n is the average number of moles of EO added per hydroxyl group of the alcohol. The number of moles of EO added to the component (a) as a whole is 1 to 70, preferably 5 to 60, and more preferably 10 to 50. When "p × n" exceeds 70, the adhesiveness and longevity of the aqueous make-up are lowered, and when it is less than 1, the freshness at the time of application is impaired.

The oxyalkylene group A ^{1 O} ratio average addition mole number and an average addition mole number of the oxyethylene group EO to the total of the average molar number of addition of the oxyethylene group EO of "n / (m + n)" is 0. It is 15 to 0.75, preferably 0.30 to 0.72, and more preferably 0.45 to 0.70. If this ratio exceeds 0.75, the adhesiveness and longevity of the aqueous make-up will decrease, and if it is less than 0.15, the freshness at the time of application will be impaired.

A ¹ O and EO may be added in a block shape or in a random shape, but it is more preferable to add them in a random shape.

R ¹ is an alkyl group having 1 to 4 carbon atoms. When the ^{number of carbon atoms of R 1} is 5 or more, the hydrophilicity is lowered and the freshness at the time of application is impaired. Examples of the alkyl group include a methyl group, an ethyl group, an n-propyl group, an isopropyl group, an n-butyl group, a sec-butyl group, a tert-butyl group and the like, and a methyl group and an ethyl group are preferable.

The component (a) of the present invention can be produced by a known method. For example, it is obtained by addition-polymerizing ethylene oxide and an alkylene oxide having 3 to 4 carbon atoms to a compound having a hydroxyl group, and then ether-reacting an alkyl halide in the presence of an alkali metal.

When the total mass of the components (a), (b), (c) and (d) is 100% by mass, the content of the component (a) is 0.1 to 25% by mass, preferably 0.5. It is ~ 20% by mass, more preferably 1 to 15% by mass. When the content of the component (a) is less than 0.1% by mass, the freshness at the time of application is impaired, and the adhesiveness of the aqueous make-up is insufficient. Further, when the content of the component (a) exceeds 25% by mass, the adhesiveness of the aqueous make-up deteriorates.

[Component (b)]
In the present invention, the alkylene oxide derivative represented by the general formula (2), A 2 ^O is an oxyalkylene group having 3 carbon atoms, particularly oxypropylene groups include oxy trimethylene group, preferably, It is an oxypropylene group.

x is the average number of moles of AO groups added, which is 1 ≦ x ≦ 40, preferably 3 ≦ m ≦ 30, and more preferably 5 ≦ m ≦ 20. If x is more than 40, the freshness at the time of application is impaired, and if x is less than 1, the adhesiveness of the aqueous make-up and the long-lasting makeup are deteriorated.

y is the average number of moles of oxyethylene groups added, with 3 ≦ y ≦ 60, preferably 5 ≦ y ≦ 50, and more preferably 10 ≦ y ≦ 30. If y is more than 60, the adhesiveness and longevity of the aqueous make-up are deteriorated, and if y is less than 3, the freshness at the time of application is impaired.

Component said to the sum of the average addition mole number of oxyalkylene groups ^{A 2} O and the average molar number of addition of the oxyethylene group EO in (b) oxyethylene group ratio of EO x / (x + y) is from 0.35 to 0. It is 85, preferably 0.45 to 0.80, and more preferably 0.50 to 0.70. If this ratio is less than 0.35, the freshness at the time of application is impaired, and if it exceeds 0.85, the adhesiveness and makeup retention of the aqueous make-up are lowered.

The oxyethylene group EO and the oxypropylene group A ² O are randomly added from the viewpoint of non-stickiness.

R ² is an alkyl group having 1 to 4 carbon atoms. If the number of carbon atoms in R ² is 5 or more, hydrophilicity is lowered, freshness upon with the coating is reduced. Examples of the alkyl group include a methyl group, an ethyl group, an n-propyl group, an isopropyl group, an n-butyl group, a sec-butyl group, a tert-butyl group and the like. Preferably, it is a methyl group or an n-butyl group.

The component (b) of the present invention can be produced by a known method. For example, it can be obtained by addition polymerization of ethylene oxide and alkylene oxide having 3 to 4 carbon atoms to a compound having a hydroxyl group.

When the total mass of the components (a), (b), (c) and (d) is 100% by mass, the content of the component (b) is 0.01 to 4 % by mass, preferably 0.03. It is ~ 4% by mass, more preferably 0.05 to 3% by mass. When the content of the component (b) is less than 0.01% by mass, the adhesiveness and makeup retention of the aqueous make-up are lowered, and when it exceeds 4% by mass, the makeup retention is deteriorated.

[Component (c)]
The component (c) of the present invention is a water-soluble thickener, for example, a natural polysaccharide such as carrageenan, xanthan gum, dextrin, methyl cellulose, hyaluronic acid, and chitosan; Sugars; polyvinyl alcohol, polyacrylic acid, polymethacrylic acid, carboxyvinyl polymer, (acrylic acid /
Examples thereof include synthetic polymers such as alkyl acrylate (10 to 30 carbon atoms) copolymers. Of these, from the viewpoint of long-lasting makeup and non-stickiness, kitan sun gum, hydroxypropyl methylcellulose, carboxyvinyl polymer, and (acrylic acid / alkyl acrylate (10 to 30 carbon atoms) copolymer) are preferable.

When the total mass of the components (a), (b), (c) and (d) is 100% by mass, the content of the component (c) is 0.01 to 5% by mass, preferably 0.05. It is ~ 4% by mass, more preferably 0.1 to 3% by mass. When the content of the component (c) is less than 0.01% by mass, the adhesiveness of the aqueous make-up is lowered, and when it exceeds 5% by mass, the makeup lasts poorly.

[Component (d)]
The component (d) of the present invention is water, and water generally used in cosmetics, pharmaceuticals and the like can be used. For example, ion-exchanged water, purified water, or the like can be used.

The content of the component (d) is the balance obtained by subtracting the total content of the components (a), (b) and (c) from 100% by mass.

[Ratio of each component]
In the present invention, the mass ratio ((b) / (a)) of the component (b) to the component (a) in the total amount of the composition is 1/200 to 1/6, preferably 1/150 to 1/1. 10, more preferably 1/100 to 1/20. If (b) / (a) is less than 1/200, the adhesiveness of the water-based make-up is insufficient, and if (b) / (a) exceeds 1/6, the make-up lasting of the water-based make-up is poor. Become.

Other ingredients can be added to the skin cosmetics of the present invention as long as the effects of the present invention are not impaired. Other optional ingredients include alcohols, polysaccharides, sugars, polysaccharides, amino acids, various surfactants, organic salts, inorganic salts, pH regulators, chelating agents, antioxidants, bactericides, blood flow promoters, etc. Antioxidants, UV absorbers, UV scatterers, vitamins, pigments, fragrances and the like can be appropriately blended.

Next, the present invention will be specifically described with reference to Examples.
First, each compound shown in Table 1 was synthesized.

<Synthesis of compounds a1 to a2, compounds a'1, a'3, a'4>
1 mol of the alcohol shown in Table 1 and 0.1% by mass of potassium hydroxide as a catalyst with respect to the final weight of the alkylene oxide derivative were charged in the autoclave, the air in the autoclave was replaced with dry nitrogen, and then the mixture was stirred. However, the catalyst was completely dissolved at 140 ° C. Next, a mixture of ethylene oxide p × n mol and propylene oxide p × m mol was added dropwise by a dropping device, and the mixture was reacted at 140 ° C. for 2 hours after the completion of the dropping. Next, p × 2 mol of potassium hydroxide was charged, the inside of the autoclave was replaced with dry nitrogen, and then methyl chloride p × 3 mol was press-fitted at a temperature of 80 to 130 ° C. and reacted for 5 hours. Then, the reaction composition was taken out from the autoclave, neutralized with hydrochloric acid to adjust the pH to 6 to 7, and dehydrated at 100 ° C. for 1 hour under reduced pressure of −0.095 MPa (50 mmHg) to remove the contained water. Further, filtration was carried out to remove the salt produced by dehydration to obtain compounds a1, a2, a'1, a'3 and a'4.

The hydroxyl values of all of these compounds were less than 0.1, and it was confirmed that the hydrogen atom was almost completely converted to a methyl group.

<Synthesis of compound a3>
1 mol of propylene glycol (PG) and 0.1% by mass of potassium hydroxide as a catalyst with respect to the final weight of the alkylene oxide derivative were charged in the autoclave, the air in the autoclave was replaced with dry nitrogen, and then the mixture was stirred. The catalyst was completely dissolved at 140 ° C. Next, 41 mol of propylene oxide was dropped by a dropping device. Subsequently, 36 mol of ethylene oxide was added dropwise, and after completion of the addition, the reaction was carried out at 140 ° C. for 2 hours. Next, 4 mol of potassium hydroxide was charged, the inside of the autoclave was replaced with dry nitrogen, and then 6 mol of methyl chloride was press-fitted at a temperature of 80 to 130 ° C. and reacted for 5 hours. Then, the reaction composition was taken out from the autoclave, neutralized with hydrochloric acid to adjust the pH to 6 to 7, and dehydrated at 100 ° C. for 1 hour under reduced pressure of −0.095 MPa (50 mmHg) to remove the contained water. Further, filtration was carried out to remove the salt produced by dehydration to obtain compound a3.
It was confirmed that the hydroxyl value of compound a3 was less than 0.1, and that the hydrogen atom was almost completely converted to a methyl group.

<Synthesis of compound a4>
1 mol of pentalit and potassium hydroxide as a catalyst were charged in an autoclave in an amount of 0.1% by mass based on the final weight of the alkylene oxide derivative, the air in the autoclave was replaced with dry nitrogen, and then the catalyst was added at 140 ° C. with stirring. Completely dissolved. Next, a mixture of 15 mol of propylene oxide and 50 mol of ethylene oxide was added dropwise by a dropping device, and the mixture was reacted at 140 ° C. for 2 hours. Next, 8 mol of potassium hydroxide was charged, the inside of the autoclave was replaced with dry nitrogen, and then 10 mol of methyl chloride was press-fitted at a temperature of 80 to 130 ° C. and reacted for 5 hours. Then, the reaction composition was taken out from the autoclave, neutralized with hydrochloric acid to adjust the pH to 6 to 7, and dehydrated at 100 ° C. for 1 hour under reduced pressure of −0.095 MPa (50 mmHg) to remove the contained water. Further, filtration was carried out to remove the salt produced by dehydration to obtain compound a4.
The hydroxyl value of compound a4 was less than 0.1, and it was confirmed that the hydrogen atom was almost completely converted to a methyl group.

<Synthesis of compound a'2>
After charging 1 mol (46 g) of ethanol and 1.07 g of potassium hydroxide (0.1% by mass based on the final weight of the alkylene oxide derivative) as a catalyst in the autoclave and replacing the air in the autoclave with a dry nitrogen tube. The catalyst was completely dissolved at 140 ° C. with stirring. Next, a mixture of 14 mol (616 g) of ethylene oxide and 7 mol (406 g) of propylene oxide was added dropwise from the dropping device, and the mixture was reacted at 140 ° C. for 2 hours after the completion of the dropping. Next, 2 mol (56.1 g) of potassium hydroxide and 5 mol (1667 g) of 1-bromooctadecane were charged, and the autoclave was replaced with dry nitrogen and then reacted for 5 hours. Then, the reaction composition was taken out from the autoclave, neutralized with hydrochloric acid to adjust the pH to 6 to 7, and dehydrated at 100 ° C. for 1 hour under reduced pressure of −0.095 MPa (50 mmHg) to remove the contained water. Further, filtration was carried out to remove the salt produced by dehydration to obtain compound a'2.
The hydroxyl value of compound a'2 was 0.08, and it was confirmed that almost all hydrogen atoms were converted to methyl groups.

<Synthesis of compounds b1, b2, b'1, b'2>
1 mol of the alcohol shown in Table 2 below and 0.1% by mass of potassium hydroxide as a catalyst with respect to the final weight of the alkylene oxide derivative were charged in the autoclave, the air in the autoclave was replaced with dry nitrogen, and then the mixture was stirred. The catalyst was completely dissolved at 140 ° C. Next, a mixture of x mol of ethylene oxide and y mol of propylene oxide (compound b'1 contained only ethylene oxide and compound b'2 contained only propylene oxide) was added dropwise by a dropping device, and the mixture was reacted at 140 ° C. for 2 hours after the completion of the dropping. Then, the reaction composition was taken out from the autoclave, neutralized with hydrochloric acid to adjust the pH to 6 to 7, and dehydrated at 100 ° C. for 1 hour under reduced pressure of −0.095 MPa (50 mmHg) to remove the contained water. Further, filtration was carried out to remove the salt produced by dehydration to obtain compounds b1, b2, b'1 and b'2.

<Preparation method of all-in-one beauty essence>
(1) When using arginine, prepare a 10% aqueous solution in advance.
(2) While mixing the component (d) (ion-exchanged water) with a disper mixer, the component (c) is gradually added and dissolved.
(3) Subsequently, the component (a), the component (b), and other components are added, and the mixture is stirred until uniform.

<Evaluation method>
A usability test was conducted by 20 specialized panelists. Take 0.2g of the prepared all-in-one beauty essence and have it applied to the inner part of the forearm. Persistence was evaluated by each panelist on a scale of 0 to 3 in the following absolute evaluation. Then, the total score was classified into 5 grades from AA to D, and AA, A and B were regarded as passing.

<Final evaluation based on the total absolute score>
AA: Total score is 50-60 points A: Total score is 40-49 points B: Total score is 30-39 points C: Total score is 20-29 points D: Total score is less than 20 points

(1) Freshness at the time of application (absolute evaluation standard)
(Score): (Evaluation)
3: Very good freshness at the time of application 2: Good freshness at the time of application 1: Not much freshness at the time of application 0: No freshness at all at the time of application

(2) Adhesion of water-based makeup After applying the prepared all-in-one beauty essence to the skin, 0.1 g of a commercially available water-based makeup cosmetic was applied, and the adhesion to the skin was evaluated according to the following criteria.
(Absolute evaluation criteria)
(Score): (Evaluation)
3: Very good adhesion of water-based makeup 2: Good adhesion of water-based makeup 1: Not very good adhesion of water-based makeup 0: No water-based makeup adheres

(3) Persistence of water-based make-up The durability of water-based make-up applied as described above after 6 hours was evaluated according to the following criteria.
(Absolute evaluation criteria)
(Score): (Evaluation)
3: The durability of the water-based make-up is extremely good and the makeup film is not broken. 2: The durability of the water-based makeup is good and the makeup film is hardly broken. 1: The durability of the water-based makeup is not so good. Not good, some makeup film is broken 0: Aqueous make-up is not very durable and the makeup film is almost broken

<Examples 1 to 6 and Comparative Examples 1 to 12>
An all-in-one beauty essence was prepared and evaluated by the above method. Tables 3-5 show the formulations and results. All formulations were prepared on a 100 g scale.

In Examples 1 to 6, a fresh feeling of use was obtained at the time of application in any of the formulations, and the adhesiveness of the aqueous make-up cosmetic to the skin and the long-lasting makeup were good.

On the other hand, with respect to Comparative Examples 1 to 12, sufficient effects could not be obtained.
That is, in Comparative Examples 1 to 4, since the comparative component (a') having a structure outside the range of the component (a) of the present invention was contained, the effect of the present invention could not be satisfied at the same time. In Comparative Examples 5 and 6, since the comparative component (b') having a structure outside the range of the component (b) of the present invention was contained, the effects of the present invention could not be satisfied at the same time.

In Comparative Example 7, since the component (b) was not contained, the adhesiveness of the aqueous make-up was insufficient. In Comparative Example 8, since b / a exceeded 1/6, the sustainability of aqueous make-up was insufficient. In Comparative Example 9, the contents of the component (a) and the component (b) exceeded 25% by mass and 5% by mass, respectively, so that all the effects were insufficient.

In Comparative Example 10, since the component (a) was not contained, the freshness at the time of application and the durability of the aqueous make-up were insufficient. In Comparative Example 11, the content of the component (c) was 6.0% by mass, which was higher than the range of the present invention, and in Comparative Example 12, the content of the component (c) was 0% by mass. The effect could not be satisfied at the same time.

Claims (1)

The following component (a) is contained in an amount of 0.1 to 25% by mass, the component (b) is contained in an amount of 0.01 to 4 % by mass, and the component (c) is contained in an amount of 0.01 to 5% by mass. A skin cosmetic having a mass ratio ((b) / (a)) to (a) of 1/200 to 1/6.

(A) Polyalkylene oxide derivative represented by the following formula (1)

Z- [O (A ¹ O) _m (EO) _n- R ¹ ] p ... (1)

(In equation (1),
Z is a residue obtained by removing all hydroxyl groups from an alcohol having 1 to 6 carbon atoms.
p is the valence of the alcohol, which is 1 or more and 6 or less.
R ¹ is an alkyl group having 1 to 4 carbon atoms.
A ¹ O is an oxyalkylene group having 3 to 4 carbon atoms.
EO is an oxyethylene group
Wherein the average addition molar number p × m of the oxyalkylene group A ^{1 O} has to satisfy 1 ≦ p × m ≦ 70 in derivatives,
The average number of moles p × n added to the oxyethylene group EO in the derivative satisfies 1 ≦ p × n ≦ 70.
The oxyalkylene group A ^{1 O} ratio average addition mole number and an average addition mole number of the oxyethylene group EO to the total of the average molar number of addition of the oxyethylene group EO of n / (m + n) is from 0.15 to 0 It is .75. )

(B) An alkylene oxide derivative represented by the following formula (2)

R ² O-[(A ² O) _x (EO) _y ] -H ... (2)

(In equation (2),
R ² is an alkyl group having 1 to 4 carbon atoms.
A ² O is an oxyalkylene group having 3 carbon atoms.
EO is an oxyethylene group
x is an average addition number of moles of the oxyalkylene groups A ^{2 O,}
Satisfying 1 ≦ x ≦ 40
y is the average number of moles of the oxyethylene group added, satisfying 3 ≦ y ≦ 60.
The oxyalkylene group ^{A 2} the O average addition mole number of the to the total of the average molar number of addition of the oxyethylene group EO an oxyethylene group ratio of EO x / (x + y) is from 0.35 to 0.85,
The oxyalkylene group A ² O and the oxyethylene group EO are randomly added. )

(C) Water-soluble thickener

(D) Water