JP6836506B2 - 細菌性呼吸器感染症を処置するためのピオシン類の肺投与 - Google Patents
細菌性呼吸器感染症を処置するためのピオシン類の肺投与 Download PDFInfo
- Publication number
- JP6836506B2 JP6836506B2 JP2017535141A JP2017535141A JP6836506B2 JP 6836506 B2 JP6836506 B2 JP 6836506B2 JP 2017535141 A JP2017535141 A JP 2017535141A JP 2017535141 A JP2017535141 A JP 2017535141A JP 6836506 B2 JP6836506 B2 JP 6836506B2
- Authority
- JP
- Japan
- Prior art keywords
- piocin
- piosin
- mice
- treated
- piocins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Heart & Thoracic Surgery (AREA)
- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- AIDS & HIV (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1416788.6A GB201416788D0 (en) | 2014-09-23 | 2014-09-23 | Therapeutic applications for pyocins |
| GB1416788.6 | 2014-09-23 | ||
| PCT/EP2015/071768 WO2016046218A1 (en) | 2014-09-23 | 2015-09-22 | Pulmonary administration of pyocins for treating bacterial respiratory infections |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017529398A JP2017529398A (ja) | 2017-10-05 |
| JP2017529398A5 JP2017529398A5 (cg-RX-API-DMAC7.html) | 2018-10-25 |
| JP6836506B2 true JP6836506B2 (ja) | 2021-03-03 |
Family
ID=51869352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017535141A Active JP6836506B2 (ja) | 2014-09-23 | 2015-09-22 | 細菌性呼吸器感染症を処置するためのピオシン類の肺投与 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11643442B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3200813B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6836506B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN107073073B (cg-RX-API-DMAC7.html) |
| CA (1) | CA2962117C (cg-RX-API-DMAC7.html) |
| GB (1) | GB201416788D0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016046218A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11857606B2 (en) | 2017-12-14 | 2024-01-02 | Bactoclear Holdings Pte. Ltd. | Therapeutic bacteriocins |
| US20220024992A1 (en) * | 2018-11-02 | 2022-01-27 | The Rockefeller University | Compositions and methods comprising lysocins as bioengineered antimicrobials for use in targeting gram-negative bacteria |
| EP3957995A1 (en) * | 2018-11-19 | 2022-02-23 | Bioaster | Methods and reagents for multiplex binding experiments |
| WO2020245376A1 (en) * | 2019-06-06 | 2020-12-10 | Nomad Bioscience Gmbh | Klebicins for the control of klebsiella |
| EP4248987A1 (en) * | 2022-03-21 | 2023-09-27 | Nomad Bioscience GmbH | Chimeric bacteriocins and method for the control of pseudomonas |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4861754A (en) | 1986-05-28 | 1989-08-29 | Farkas Himsley Hannah | Bacteriocins and compositions thereof in anti-viral treatment |
| JP3655645B2 (ja) * | 1992-02-28 | 2005-06-02 | 中外製薬株式会社 | 経粘膜投与剤 |
| ATE202481T1 (de) * | 1996-11-15 | 2001-07-15 | Pathogenesis Corp | Reines, biologisch aktives colistin, seine bestandteile und eine colistin-zubereitung zur behandlung von entzündungen der atemwege |
| WO2001014579A2 (en) * | 1999-08-26 | 2001-03-01 | Vion Pharmaceuticals, Inc. | Compositions and methods for delivery of an agent using attenuated salmonella containing phage |
| US20060229244A1 (en) * | 2004-09-27 | 2006-10-12 | Robert Dorit | Engineered bacteriocins and bacteriocin combinations and methods for treating bacterial based infections |
| US7700729B2 (en) * | 2006-05-15 | 2010-04-20 | Avidbiotics Corporation | Modified bacteriocins and methods for their use |
| JP5603070B2 (ja) * | 2006-05-15 | 2014-10-08 | アビッドバイオティクス コーポレイション | 改変バクテリオシン及びその使用方法 |
| US20110129438A1 (en) * | 2006-06-28 | 2011-06-02 | James Robert Swartz | Immunogenic protein constructs |
| US20080286236A1 (en) * | 2007-05-14 | 2008-11-20 | Avidbiotics Corporation | Inhibition of yersinia pestis |
| CA2833176C (en) * | 2011-04-12 | 2023-05-16 | C.B. Appaiah | Chimeric antibacterial polypeptides |
| GB201116234D0 (en) * | 2011-09-20 | 2011-11-02 | Aseptika Ltd | Biomarkers for respiratory infection |
-
2014
- 2014-09-23 GB GBGB1416788.6A patent/GB201416788D0/en not_active Ceased
-
2015
- 2015-09-22 CN CN201580057704.5A patent/CN107073073B/zh active Active
- 2015-09-22 JP JP2017535141A patent/JP6836506B2/ja active Active
- 2015-09-22 WO PCT/EP2015/071768 patent/WO2016046218A1/en not_active Ceased
- 2015-09-22 US US15/512,548 patent/US11643442B2/en active Active
- 2015-09-22 CA CA2962117A patent/CA2962117C/en active Active
- 2015-09-22 EP EP15767472.2A patent/EP3200813B1/en active Active
-
2023
- 2023-02-23 US US18/173,333 patent/US12162911B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3200813A1 (en) | 2017-08-09 |
| CA2962117C (en) | 2023-04-25 |
| CA2962117A1 (en) | 2016-03-31 |
| US12162911B2 (en) | 2024-12-10 |
| US20170240602A1 (en) | 2017-08-24 |
| US11643442B2 (en) | 2023-05-09 |
| GB201416788D0 (en) | 2014-11-05 |
| CN107073073A (zh) | 2017-08-18 |
| US20230303636A1 (en) | 2023-09-28 |
| CN107073073B (zh) | 2021-07-09 |
| WO2016046218A1 (en) | 2016-03-31 |
| EP3200813B1 (en) | 2021-04-07 |
| JP2017529398A (ja) | 2017-10-05 |
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