JP6811724B2 - 細胞療法に対する臨床応答を決定するためのバイオマーカー - Google Patents

細胞療法に対する臨床応答を決定するためのバイオマーカー Download PDF

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JP6811724B2
JP6811724B2 JP2017555636A JP2017555636A JP6811724B2 JP 6811724 B2 JP6811724 B2 JP 6811724B2 JP 2017555636 A JP2017555636 A JP 2017555636A JP 2017555636 A JP2017555636 A JP 2017555636A JP 6811724 B2 JP6811724 B2 JP 6811724B2
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ラ ローサ，オルガ デ
ラ ローサ，オルガ デ
ダレマンズ，ウィルフリード
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ティジェニクス エス．エー．ユー．
ティジェニクス エス．エー．ユー．
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    • A—HUMAN NECESSITIES
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539—MHC-molecules, e.g. HLA-molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
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    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
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JP2017555636A 2015-04-24 2016-04-25 細胞療法に対する臨床応答を決定するためのバイオマーカー Active JP6811724B2 (ja)

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EP15382206 2015-04-24
EP15382206.9 2015-04-24
PCT/EP2016/059196 WO2016170187A2 (en) 2015-04-24 2016-04-25 Biomarkers for determining the clinical response to cell therapy

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JP2018513388A JP2018513388A (ja) 2018-05-24
JP2018513388A5 JP2018513388A5 (enExample) 2019-05-30
JP6811724B2 true JP6811724B2 (ja) 2021-01-13

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US (1) US10746729B2 (enExample)
EP (1) EP3286562B1 (enExample)
JP (1) JP6811724B2 (enExample)
CA (1) CA2983950A1 (enExample)
HK (1) HK1250176A1 (enExample)
IL (1) IL255243B (enExample)
WO (1) WO2016170187A2 (enExample)

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US12303534B2 (en) 2018-06-05 2025-05-20 Medipost Co., Ltd Pharmaceutical composition comprising mesenchymal stem cells as effective ingredient for prevention or treatment of inflammatory disease
WO2020009648A1 (en) * 2018-07-02 2020-01-09 Nextcell Pharma Ab Msc prediction algorithm
JP7628499B2 (ja) * 2019-02-27 2025-02-10 武田薬品工業株式会社 同種異系療法のための改良された幹細胞集団

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CA2564679C (en) * 2004-03-22 2015-06-23 Osiris Therapeutics, Inc. Mesenchymal stem cells and uses therefor
US20080095749A1 (en) * 2004-03-22 2008-04-24 Sudeepta Aggarwal Mesenchymal stem cells and uses therefor
ES2595103T3 (es) * 2007-10-17 2016-12-27 Txcell Células Tr1, células madre mesenquimales y usos de estas
US20140219921A1 (en) * 2012-12-21 2014-08-07 Rutgers, The State University Of New Jersey Immunomodulating compositions and methods
ES2748825T3 (es) * 2013-03-15 2020-03-18 Tigenix S A U Biomarcadores de linfocitos para determinar la respuesta clínica a la terapia celular
US20160120910A1 (en) * 2013-06-25 2016-05-05 Tigenix S.A.U. Cell populations having immunoregulatory activity, methods for the preparation and uses thereof

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EP3286562B1 (en) 2020-08-12
US10746729B2 (en) 2020-08-18
WO2016170187A3 (en) 2016-12-01
HK1250176A1 (zh) 2018-11-30
EP3286562A2 (en) 2018-02-28
IL255243B (en) 2021-04-29
IL255243A0 (en) 2017-12-31
US20180156785A1 (en) 2018-06-07
WO2016170187A2 (en) 2016-10-27
CA2983950A1 (en) 2016-10-27
JP2018513388A (ja) 2018-05-24

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