JP6755256B2 - 骨折リスクの低減におけるＰＴＨｒＰアナログの使用 - Google Patents

骨折リスクの低減におけるＰＴＨｒＰアナログの使用 Download PDF

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JP6755256B2
JP6755256B2 JP2017546245A JP2017546245A JP6755256B2 JP 6755256 B2 JP6755256 B2 JP 6755256B2 JP 2017546245 A JP2017546245 A JP 2017546245A JP 2017546245 A JP2017546245 A JP 2017546245A JP 6755256 B2 JP6755256 B2 JP 6755256B2
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avaloparatide
bmd
bone
treated
teriparatide
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JP2018508530A (ja
JP2018508530A5 (enExample
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ハタスリー，ガリー
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ラジウス ヘルス，インコーポレイテッド
ラジウス ヘルス，インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2017546245A 2015-03-03 2016-03-03 骨折リスクの低減におけるＰＴＨｒＰアナログの使用 Active JP6755256B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201562127729P 2015-03-03 2015-03-03
US62/127,729 2015-03-03
US201562165841P 2015-05-22 2015-05-22
US62/165,841 2015-05-22
US201562201564P 2015-08-05 2015-08-05
US62/201,564 2015-08-05
US201562239733P 2015-10-09 2015-10-09
US62/239,733 2015-10-09
US201662278762P 2016-01-14 2016-01-14
US62/278,762 2016-01-14
PCT/US2016/020787 WO2016141250A1 (en) 2015-03-03 2016-03-03 USES OF PTHrP ANALOGUE IN REDUCING FRACTURE RISK

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020141522A Division JP7049412B2 (ja) 2015-03-03 2020-08-25 骨折リスクの低減におけるＰＴＨｒＰアナログの使用

Publications (3)

Publication Number Publication Date
JP2018508530A JP2018508530A (ja) 2018-03-29
JP2018508530A5 JP2018508530A5 (enExample) 2019-04-11
JP6755256B2 true JP6755256B2 (ja) 2020-09-16

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Family Applications (5)

Application Number Title Priority Date Filing Date
JP2017546245A Active JP6755256B2 (ja) 2015-03-03 2016-03-03 骨折リスクの低減におけるＰＴＨｒＰアナログの使用
JP2020141522A Active JP7049412B2 (ja) 2015-03-03 2020-08-25 骨折リスクの低減におけるＰＴＨｒＰアナログの使用
JP2022050196A Pending JP2022075999A (ja) 2015-03-03 2022-03-25 骨折リスクの低減におけるＰＴＨｒＰアナログの使用
JP2023117588A Pending JP2023129523A (ja) 2015-03-03 2023-07-19 骨折リスクの低減におけるＰＴＨｒＰアナログの使用
JP2025064970A Pending JP2025100689A (ja) 2015-03-03 2025-04-10 骨折リスクの低減におけるＰＴＨｒＰアナログの使用

Family Applications After (4)

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JP2020141522A Active JP7049412B2 (ja) 2015-03-03 2020-08-25 骨折リスクの低減におけるＰＴＨｒＰアナログの使用
JP2022050196A Pending JP2022075999A (ja) 2015-03-03 2022-03-25 骨折リスクの低減におけるＰＴＨｒＰアナログの使用
JP2023117588A Pending JP2023129523A (ja) 2015-03-03 2023-07-19 骨折リスクの低減におけるＰＴＨｒＰアナログの使用
JP2025064970A Pending JP2025100689A (ja) 2015-03-03 2025-04-10 骨折リスクの低減におけるＰＴＨｒＰアナログの使用

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Country Link
US (8) US20170065682A1 (enExample)
EP (2) EP4137147A3 (enExample)
JP (5) JP6755256B2 (enExample)
AU (3) AU2016226103A1 (enExample)
CA (1) CA2977812A1 (enExample)
DK (1) DK3265115T3 (enExample)
ES (1) ES2927067T3 (enExample)
WO (1) WO2016141250A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017253674B2 (en) 2016-04-18 2021-07-29 Kindeva Drug Delivery L.P. Formulations of abaloparatide, transdermal patches thereof, and uses thereof
CA3045458A1 (en) * 2016-11-30 2018-06-07 Purdue Research Foundation Fracture targeted bone regeneration through parathyroid hormone receptor stimulation
EP3796941A4 (en) 2018-05-30 2022-12-28 Purdue Research Foundation Targeting anabolic drugs for accelerated fracture repair
EP3908605A1 (en) * 2019-01-11 2021-11-17 Radius Health, Inc. Methods for detecting neutralizing antibodies to parathyroid hormone (pth) and parathyroid hormone-related peptide (pthrp) analog
WO2020166561A1 (ja) 2019-02-14 2020-08-20 富士フイルム株式会社 骨折リスク評価値取得装置及びその作動方法並びに骨折リスク評価値取得プログラム
CN114364327A (zh) * 2019-09-12 2022-04-15 雷迪厄斯健康公司 用阿巴帕肽改善脊柱融合的方法
CN112646042A (zh) * 2019-10-10 2021-04-13 陕西麦科奥特科技有限公司 活性多肽化合物
AU2022205801A1 (en) * 2021-01-05 2023-07-13 Radius Health, Inc. Treatment of long bone fractures with abaloparatide
EP4346878A1 (en) * 2021-05-25 2024-04-10 Radius Health, Inc. Treatment and prevention of osteoporosis in high body mass index individuals
WO2025032376A1 (en) * 2023-08-04 2025-02-13 Precise Biopharma Pvt Ltd A room temperature stable solution for injection of abaloparatide

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9702401D0 (sv) * 1997-06-19 1997-06-19 Astra Ab Pharmaceutical use
MXPA04006728A (es) * 2002-01-10 2005-08-19 Osteotrophin Llc Tratamiento de desordenes oseos con medicamentos anabolicos esqueleticos.
CA2621264A1 (en) * 2005-09-06 2007-11-15 Zelos Therapeutics, Inc. Parathyroid hormone analogues and methods of use
AR062522A1 (es) * 2006-08-25 2008-11-12 Ares Trading Sa Tratamiento de desordenes en cartilagos
US7803770B2 (en) * 2006-10-03 2010-09-28 Radius Health, Inc. Method of treating osteoporosis comprising administration of PTHrP analog
JP5375611B2 (ja) * 2006-10-03 2013-12-25 ラジウス ヘルス，インコーポレイテッド 骨同化作用を有するタンパク質のための薬物送達方法
WO2010022176A1 (en) * 2008-08-19 2010-02-25 Ferring International Center S.A. Methods of treatment for skeletal conditons
US20130006217A1 (en) * 2011-04-22 2013-01-03 Gary Hattersley METHOD OF DRUG DELIVERY FOR PTH, PTHrP AND RELATED PEPTIDES
WO2014004465A1 (en) * 2012-06-25 2014-01-03 The Brigham And Women's Hospital, Inc. Targeted therapeutics
SI3359241T1 (sl) * 2015-10-09 2021-11-30 Radius Health, Inc. Formulacije PTHRP-analogov, transdermalni obliži le-teh in uporabe le-teh

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Publication number Publication date
EP3265115A1 (en) 2018-01-10
JP2022075999A (ja) 2022-05-18
JP2018508530A (ja) 2018-03-29
CA2977812A1 (en) 2016-09-09
US20250195619A1 (en) 2025-06-19
WO2016141250A1 (en) 2016-09-09
US20200376088A1 (en) 2020-12-03
EP3265115B1 (en) 2022-06-22
US20220125887A1 (en) 2022-04-28
US20200061160A1 (en) 2020-02-27
US20230321199A1 (en) 2023-10-12
US20170368148A1 (en) 2017-12-28
EP4137147A3 (en) 2023-04-05
JP2020189884A (ja) 2020-11-26
AU2020267182A1 (en) 2020-12-03
AU2024202952A1 (en) 2024-05-23
AU2016226103A1 (en) 2017-08-31
JP2023129523A (ja) 2023-09-14
ES2927067T3 (es) 2022-11-02
DK3265115T3 (da) 2022-09-05
US20230381283A1 (en) 2023-11-30
JP2025100689A (ja) 2025-07-03
US20170065682A1 (en) 2017-03-09
JP7049412B2 (ja) 2022-04-06
EP4137147A2 (en) 2023-02-22
EP3265115A4 (en) 2019-05-22

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