JP6751756B2 - 低密度リポタンパク質コレステロールレベルを低下させるためのｃｄ２４の使用 - Google Patents
低密度リポタンパク質コレステロールレベルを低下させるためのｃｄ２４の使用 Download PDFInfo
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2319/00—Fusion polypeptide
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
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Applications Claiming Priority (3)
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| US201562158157P | 2015-05-07 | 2015-05-07 | |
| US62/158,157 | 2015-05-07 | ||
| PCT/US2016/031109 WO2016179456A1 (en) | 2015-05-07 | 2016-05-06 | Use of cd24 for lowering low-density lipoprotein cholesterol levels |
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| JP2018515605A JP2018515605A (ja) | 2018-06-14 |
| JP2018515605A5 JP2018515605A5 (cg-RX-API-DMAC7.html) | 2019-04-11 |
| JP6751756B2 true JP6751756B2 (ja) | 2020-09-09 |
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| HRP20201651T1 (hr) * | 2015-05-07 | 2020-12-25 | Oncoimmune, Inc. | Uporaba cd24 za snižavanje razina lipoproteina niske gustoće kolesterola |
| JP2020510020A (ja) * | 2017-03-07 | 2020-04-02 | オンコイミューン， インコーポレイテッド | 全身性エリテマトーデスを治療するために可溶性ｃｄ２４を使用する方法 |
| WO2019113123A1 (en) * | 2017-12-04 | 2019-06-13 | Precithera, Inc. | TGF-ß RECEPTOR FUSION PROTEINS AND OTHER TGF-ß ANTAGONISTS FOR REDUCING TGF-ß SIGNALING |
| CN112543643A (zh) * | 2018-03-05 | 2021-03-23 | 肿瘤免疫股份有限公司 | 使用可溶性cd24用于治疗获得性免疫缺陷综合征（hiv/aids）的方法 |
| MA52811A (fr) * | 2018-06-04 | 2022-03-16 | Oncoimmune Inc | Procédés d'utilisation de cd24 pour la prévention et le traitement d'une rechute de la leucémie |
| WO2020084034A1 (en) | 2018-10-26 | 2020-04-30 | F. Hoffmann-La Roche Ag | Multispecific antibody screening method using recombinase mediated cassette exchange |
| CA3128503A1 (en) * | 2019-02-06 | 2020-08-13 | Oncoimmune, Inc. | Targeting cd24-siglec interactions for treating subjects with prediabetes or diabetes |
| US20220000973A1 (en) * | 2019-02-06 | 2022-01-06 | Oncolmmune, Inc. | Targeting CD24-Siglec Interactions for the Treatment and Prevention of Nonalcoholic Steatohepatitis |
| WO2021160170A1 (en) * | 2020-02-10 | 2021-08-19 | Oncoimmune, Inc. | Methods of use of soluble cd24 for treating sars-cov-2 infection |
| EP4103217A4 (en) * | 2020-02-10 | 2024-03-13 | Oncoimmune Inc. | METHOD OF USING SOLUBLE CD24 TO TREAT VIRAL PNEUMONIA |
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| US6544566B1 (en) * | 1999-04-23 | 2003-04-08 | Protein Technologies International, Inc. | Composition containing plant sterol, soy protein and isoflavone for reducing LDL cholesterol |
| AU2001259792B2 (en) * | 2000-03-29 | 2005-12-22 | The Ohio State University Research Foundation | Methods of blocking tissue destruction by autoreactive T cells |
| CN1981772A (zh) * | 2000-05-13 | 2007-06-20 | 阿彻-丹尼尔斯-米德兰公司 | 降低低密度脂蛋白胆固醇浓度的组合物和方法 |
| WO2009086284A1 (en) * | 2007-12-21 | 2009-07-09 | University Of Rochester | Cd24 as a brain tumor stem cell marker and a diagnostic and therapeutic target in primary neaural and glial tumors of the brain |
| US8163281B2 (en) * | 2009-03-04 | 2012-04-24 | The Regents Of The University Of Michigan | Treatment of drug-related side effect and tissue damage by targeting the CD24-HMGB1-Siglec10 axis |
| US8354520B2 (en) * | 2009-12-10 | 2013-01-15 | Kaohsiung Medical University | Composition and method for treating atherosclerosis, method for determining if a subject has atherosclerosis and method of screening an anti-atherosclerotic drug |
| US20130231464A1 (en) * | 2010-04-28 | 2013-09-05 | Oncolmmune, Inc. | Methods of use of soluble cd24 for therapy of rheumatoid arthritis |
| US8808697B2 (en) * | 2010-04-28 | 2014-08-19 | Oncoimmune, Inc. | Methods of use of soluble CD24 for therapy of rheumatoid arthritis |
| AU2012267489B2 (en) * | 2011-06-10 | 2017-03-16 | The Trustees Of The University Of Pennsylvania | System and method of cytomic vascular health profiling |
| HRP20201651T1 (hr) * | 2015-05-07 | 2020-12-25 | Oncoimmune, Inc. | Uporaba cd24 za snižavanje razina lipoproteina niske gustoće kolesterola |
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| US10369197B2 (en) | 2019-08-06 |
| HRP20201651T1 (hr) | 2020-12-25 |
| IL255086B (en) | 2021-08-31 |
| CN107531772A (zh) | 2018-01-02 |
| KR20170141216A (ko) | 2017-12-22 |
| HUE051866T2 (hu) | 2021-03-29 |
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| BR112017022394A2 (pt) | 2018-07-17 |
| MX2017014095A (es) | 2018-03-16 |
| ES2829235T3 (es) | 2021-05-31 |
| AU2016258084A1 (en) | 2017-11-02 |
| CN107531772B (zh) | 2021-09-21 |
| EA038520B1 (ru) | 2021-09-09 |
| US20190307841A1 (en) | 2019-10-10 |
| MX385941B (es) | 2025-03-18 |
| IL255086A0 (en) | 2017-12-31 |
| EA201792418A1 (ru) | 2018-02-28 |
| PT3292144T (pt) | 2020-11-05 |
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