JP6727280B2 - Filtration device, pharmaceutical purified water manufacturing device, and pharmaceutical purified water manufacturing method - Google Patents

Description

The present invention relates to a filtration device and the like, and more particularly to a filtration device and the like provided with a reverse osmosis membrane portion for purifying water to be treated through a reverse osmosis membrane.

For example, it has been decided to use purified water, which is water for pharmaceuticals, to manufacture pharmaceuticals. This purified water for medicine may be produced by purifying the water to be treated by a filtration means utilizing a filtration membrane such as a reverse osmosis membrane. The concentration of impurities contained in the water to be treated can be further reduced by adopting a structure in which a plurality of filtering means are permeated.

In Patent Document 1, an RO liquid feed pump is provided in a connection line that directly connects the first and second MF membrane modules and the RO membrane module, and a pressure sensor is provided on the suction side of the RO liquid feed pump. Is provided, and the primary side of the RO membrane module and the secondary side of the MF membrane module are connected by a backwash line, and when backwashing the second MF membrane module, the RO liquid feed pump sucks up the suction pressure. There is disclosed a filtration device in which the drive control is performed so as to maintain a predetermined set pressure.

JP, 2011-177653, A

However, when the filtration device has a multi-stage configuration in which three or more filtration means are connected in series without being stored in an intermediate tank or the like on the way, it may be difficult to control the permeation of the water to be treated.
The object of the present invention is to control the permeation of the water to be treated even when the filtration device has a multi-stage structure in which three or more filtration means are connected in series without storing in the middle with an intermediate tank or the like. The present invention intends to provide a filter device and the like that can be made easier.

Thus, according to the present invention, three or more filtering means that allow the water to be treated or the permeated water to pass through the filtration membrane without being stored in the middle, and three or more filtering means provided in front of each of the three or more filtering means are provided. Of the filtration means except the filtration means at the final stage, water is delivered so that the pressure of the permeated water falls within a predetermined range, and the filtration means at the final stage is subjected to permeated water. A filtering device comprising: three or more delivery means for delivering water so that the flow rate is within a predetermined range.

Further, according to the present invention, the first filtration means for purifying the water to be treated through the filtration membrane and the first permeated water which has passed through the first filtration means can be filtered without being stored. Second filtering means for further purification by permeation and third filtering means for further purification by permeating the second permeated water which has permeated the second filtration means without being stored. A first delivery means for delivering the water to be treated to the first filtration means, a second delivery means for delivering the first permeated water to the second filtration means, and a third filtration means. Third delivery means for delivering the second permeated water to the means, and first delivery means so that the pressure of the first permeated water is within a predetermined range and third delivery means. And a control means for controlling the flow rate of the third permeated water that has passed through the third filtration means to fall within a predetermined range.

Further, according to the present invention, a medical purified water production apparatus for purifying treated water to produce purified water which is water for pharmaceutical use, wherein a free chlorine removing section for removing free chlorine in the treated water, A first filtering means for purifying the water to be treated through the filtration membrane; and a first permeated water that has passed through the first filtering means. A second filtering means for further refining by permeating the filtration membrane without storing and a second permeated water that has permeated the second filtering means through the filtration membrane without storing. Third filtering means for further purification, first sending means for sending treated water to the first filtering means, and second sending means for sending the first permeated water to the second filtering means. Of the first permeated water and the third delivery means for delivering the second permeated water to the third filtration means, and the pressure of the first permeated water within the predetermined range. And a control means for controlling the third delivery means so that the flow rate of the third permeated water that has passed through the third filtration means falls within a predetermined range. A water production device is provided.

Here, the first filtering means and the second filtering means may perform filtration using a reverse osmosis membrane.

Furthermore, according to the present invention, the method for producing purified water for purifying the water to be treated and producing purified water which is water for pharmaceutical use, comprising a free chlorine removing step for removing free chlorine in the water for treatment. A first filtration step of permeating the water to be treated through the first filtration means having a filtration membrane, and a second filtration means comprising the filtration membrane of the first permeated water having passed through the first filtration means. A second filtration step of allowing permeation without storage, and a third filtration step of allowing the second permeate that has permeated through the second filtration means to permeate without storage through a third filtration means provided with a filtration membrane. A first delivery means for delivering the treated water to the first filtering means using the first delivery means for delivering the treated water so that the pressure of the first permeated water is within a predetermined range. Using the process and the third delivery means for delivering the second permeated water to the third filtration means, the flow rate of the third permeated water that has passed through the third filtration means is within a predetermined range. A third delivery step of delivering the second permeated water as described above is provided.

According to the present invention, even when the filtration device has a multi-stage configuration in which three or more filtration means are connected in series without storing in the middle with an intermediate tank or the like, it is easier to control the permeation of the water to be treated. It is possible to provide a filtration device and the like.

It is a figure explaining the pharmaceutical purified water manufacturing apparatus to which this Embodiment is applied. (A) is the figure which showed roughly about the RO unit of this Embodiment. (B) is a diagram showing a case where the RO device and the pump of the RO unit are each three. (C) is the figure which showed the case where concentrated water is processed by another RO apparatus. It is a flow chart explaining operation of the purified water manufacturing unit.

Hereinafter, modes for carrying out the invention (hereinafter, embodiments of the invention) will be described in detail. It should be noted that the present invention is not limited to the following embodiments, and can be variously modified and implemented within the scope of the gist thereof. Further, the drawings used are for explaining the present embodiment and do not show the actual size.

Hereinafter, based on the drawings, a pharmaceutical purified water manufacturing apparatus to which the present embodiment is applied will be described.

FIG. 1 is a diagram illustrating a pharmaceutical purified water manufacturing apparatus to which the present embodiment is applied.
A purified water production unit 1 which is an example of the illustrated purified drug water producing apparatus is an apparatus for purifying treated water to obtain purified drug water.

In the present embodiment, the water to be treated is, for example, normal water defined in each article of the Japanese Pharmacopoeia. This ordinary water is required to comply with the water quality standards based on Article 4 of the Water Supply Act. More specifically, as water quality standards, there are 50 items specified by the Ordinance No. 101 of the Ministry of Health, Labor and Welfare in 2003. In addition to this standard, ammonium is required to meet the standard of "0.05 mg/L or less".

As the ordinary water, for example, tap water or well water that has been sterilized is used. Therefore, normal water usually contains free chlorine derived from the chlorine agent used for disinfection. As the chlorine agent, for example, sodium hypochlorite (NaClO) is used. Examples of free chlorine resulting from this include hypochlorous acid (HOCl), hypochlorite ion (OCl ⁻ ), and the like.

In the present embodiment, the purified water for medicine is water for pharmaceutical use and is the purified water specified in each article of pharmaceuticals in the Japanese Pharmacopoeia. The purified water needs to have a content of organic carbon of 0.50 mg/L or less and a conductivity (25° C.) of 2.1 μS/cm or less. Purified water is used for manufacturing drug substances, dissolving agents in preparations, washing of pharmaceutical equipment, preparation of reagent test solutions, washing of medical equipment, preparation of preservatives for detergents for contact lenses, and the like.

As shown in the figure, the purified water production unit 1 removes free chlorine contained in the raw water tank 20, which stores the raw water to be treated, the heating device 30 which adjusts the temperature of the treated water, and the treated water. Activated carbon tower 40, prefilter 50 for removing solids from the water to be treated that has passed through activated carbon tower 40, RO (Reverse Osmosis Membrane: reverse osmosis membrane) unit 60 for purifying the water to be treated, and after purification A storage tank 70 that stores the purified water for medicine and a control unit 80 that controls the entire purified water manufacturing unit 1 are provided. The raw water tank 20, the heating device 30, the activated carbon tower 40, the prefilter 50, the RO unit 60, and the storage tank 70 are connected in series by pipes H2, H3, H4, H5, and H6 made of stainless steel or resin. Further, a loop pipe R for supplying the purified drug water from the storage tank 70, passing through the point of use, and then returning to the storage tank 70 again is provided. A pump P1 is provided in the middle of the pipe H2, and a pump P2 is provided in the loop pipe R.

In this embodiment, tap water is used as the water to be treated. Therefore, it already has a predetermined water pressure, and by utilizing this water pressure, the water to be treated first enters the raw water tank 20.

The raw water tank 20 temporarily stores the water to be treated. Then, by driving the pump P1, the water to be treated is sent from the raw water tank 20 to the subsequent apparatus.

The heating device 30 is, for example, a device including a heat exchanger. Then, for example, by supplying steam to the heat exchanger, heat is exchanged with the water to be treated and the water to be treated is heated. The temperature of the water to be treated is, for example, 5°C. In the heating device 30, during normal operation, the water to be treated is heated to, for example, 25° C. to improve the performance of a reverse osmosis membrane (RO membrane) described later.

Further, by using the heating device 30, it is possible to sterilize the device and the pipe in the subsequent stage. At this time, the heating device 30 heats the water to be treated to, for example, 85° C. and supplies it as hot water. This makes it possible to thermally sterilize the devices and pipes in the subsequent stage. It should be noted that free chlorine is not removed by the raw water tank 20 and remains in the water to be treated in the raw water tank 20, so that there is no need to sterilize the raw water tank 20. On the other hand, as will be described later in detail, since free chlorine is removed in the activated carbon tower 40, it is necessary to regularly sterilize the device and the pipe in the latter stage of the heating device 30.

The activated carbon tower 40 is an example of a free chlorine removing section, and is an apparatus for filling the inside with activated carbon. Then, by passing the treated water through the activated carbon, free chlorine contained in the treated water is removed. The activated carbon used in the activated carbon tower 40 is not particularly limited. For example, activated carbon is roughly classified into coal-based activated carbon and coconut husk activated carbon depending on the raw material for producing the activated carbon, but either can be used. However, it is preferable that impurities contained in the activated carbon be as small as possible in that the risk of elution is smaller.

It should be noted that any device other than the activated carbon tower 40 may be used as long as it is a device having a function of removing free chlorine contained in the water to be treated. For example, a device that reduces free chlorine in water to be treated using sodium sulfite or a device that decomposes free chlorine by irradiation with ultraviolet rays may be used.

The pre-filter 50 removes solids such as fine particles. In the case of the present embodiment, fine particles of activated carbon may be generated in the activated carbon tower 40. The fine particles of activated carbon may clog the reverse osmosis membrane when they pass through the RO unit 60 in the subsequent stage as they are. Therefore, the fine particles of activated carbon are removed in advance by the prefilter 50.

The RO unit 60 is a device including a reverse osmosis membrane (RO membrane), and is an example of a filtering device and a filtering unit. The RO unit 60 filters impurities contained in the water to be treated by the reverse osmosis membrane to purify the water to be treated. In the present embodiment, the reverse osmosis membrane is an example of a filtration membrane.
The reverse osmosis membrane is a membrane in which a large number of pores having a size of approximately 1 nm to 2 nm are formed, and has a property of allowing water to pass therethrough but not allowing ions to pass therethrough. Therefore, impurities such as salts and ions can be removed from the water to be treated for purification. As the reverse osmosis membrane, for example, a polyamide membrane is exemplified.

The storage tank 70 stores the water that has passed through the RO unit 60 and has become the drug purified water. Then, the pharmaceutical purified water is sent to each use point from the storage tank 70 through the loop pipe R by driving the pump P2.

Next, the RO unit 60 will be described in more detail.
FIG. 2A is a diagram schematically showing the RO unit 60 of this embodiment.
In the present embodiment, the RO unit 60 includes a plurality of RO devices that are an example of a plurality of filtering means that allow the water to be treated or the permeated water to pass through the filtration membrane without being stored midway. In this case, the filtration membrane corresponds to a reverse osmosis membrane (RO membrane). In the illustrated example, the RO device 62 and the RO device 64 are provided.

The RO device 62 is an example of a first filtering unit that purifies the water to be treated through the filtration membrane. Then, from the RO device 62, the first permeated water, which is water that has permeated the reverse osmosis membrane, and the first concentrated water that has not permeated the reverse osmosis membrane, are discharged. The first permeated water is purified water from which impurities have been removed. The first concentrated water is water in which impurities are concentrated.

The RO device 64 is an example of a second filtering unit that further refines the first permeated water that has passed through the RO device 62 by allowing the first permeated water to pass through the filtration membrane without being stored. From the RO device 64, the second permeated water that is water that has permeated the reverse osmosis membrane and the second concentrated water that has not permeated the reverse osmosis membrane are discharged. The second permeated water is water that has been further purified by removing impurities. The second concentrated water is water in which impurities are concentrated.

Further, the RO unit 60 of the present embodiment is provided with a plurality of pumps, which are an example of a plurality of delivery means provided in the preceding stages of the plurality of RO devices. In the illustrated example, the pump 61 and the pump 63 are provided.

The pump 61 is an example of a first delivery unit that delivers the water to be treated to the RO device 62. The pump 63 is an example of a second delivery unit that delivers the water to be treated to the RO device 64.

Further, in the present embodiment, the RO unit 60 includes a pressure sensor 62P that measures the pressure of the first permeated water that has passed through the RO device 62, and a flow rate sensor 64F that measures the flow rate of the second permeated water.

In the present embodiment, the pump 61, the RO device 62, the pump 63, and the RO device 64 are connected in series. By configuring the RO device in a multi-stage configuration (in this case, a two-stage configuration), the purity of the purified drug water after purifying the water to be treated can be improved. The water that has passed through the RO device 62 reaches the RO device 64 without being stored in the intermediate tank or the like. Thereby, the installation space of the RO unit 60 and the manufacturing cost of the equipment can be reduced.

As shown in FIG. 2C, the concentrated water may be further processed by an RO membrane or another RO device. This is adopted in the case of performing two-stage concentration in order to increase the recovery rate of water or to increase the concentration ratio of valuables when the concentrated water contains valuables. However, this form is not referred to herein as the RO device having a multi-stage configuration.

Further, in the present embodiment, the water is delivered to the plurality of pumps so that the pressure of the permeated water is within a predetermined range for the RO devices other than the final-stage RO device among the plurality of RO devices. Then, the RO device at the final stage is controlled to send out water so that the flow rate of permeated water falls within a predetermined range. That is, for the most downstream RO device of the plurality of RO devices, the pump immediately before the RO device is controlled so that the flow rate of the permeate of the RO device falls within a predetermined range. To do. Further, for the RO devices other than the most downstream RO device, the pumps immediately before the RO devices are controlled so that the pressure of the permeated water is within a predetermined range.

More specifically, in the example of FIG. 2A, the control unit 80 controls the pump 61 so that the pressure of the first permeated water that has permeated the RO device 62 falls within a predetermined range, The pump 63 is controlled so that the flow rate of the second permeated water that has passed through the RO device 64 falls within a predetermined range. In FIG. 2(a), the control in which the pressure is within a predetermined range is illustrated as the outlet PIC control, and the control in which the flow rate is within the predetermined range is illustrated as the outlet FIC control.

In reality, the pump 61 and the pump 63 are inverter-controlled, and this control is performed by the control unit 80. That is, the control unit 80 functions as a control means.

Although FIG. 2A shows the case where there are two RO devices and two pumps, FIG. 2B shows the case where there are three RO devices. In this case, regarding the two pumps in the previous stage excluding the pump in the final stage among the pumps indicated by P, control is performed so that the pressure of the permeated water of the RO device to which each pump sends the treated water falls within a predetermined range. I do. As for the third pump, which is the last-stage pump, this pump is controlled so that the flow rate of the permeated water of the final-stage RO device that sends the water to be treated falls within a predetermined range. The same applies when there are four or more pumps and RO devices.

Conventionally, when the RO devices have a multi-stage configuration, it is common to control the pumps that deliver the water to be processed to the respective RO devices so that the flow rate of all the permeated water is within a predetermined range. ..
However, when such control is performed, the problems described in (1) to (3) below are likely to occur.

(1) When activating the purified water production unit 1, each device is activated sequentially from the upstream side to the downstream side. At this time, the RO unit 60 first activates the pump 61 to deliver the treated water to the RO device 62, and then activates the pump 63 to deliver the treated water to the RO device 64. In this case, when the pump 61 is started, resistance occurs due to the reverse osmosis membrane of the RO device 62. Since the pump 63 has not been started yet, a larger resistance is generated. At this time, if the pump 61 is controlled so that the flow rate of the first permeated water is within a predetermined range, the load of the pump 61 is controlled to be larger. In this case, the pressure of the first permeated water suddenly rises, the pressure sensor 62P detects an excessive pressure, and as a result, the control unit 80 performs an emergency stop of the RO unit 60 in order to avoid pressure damage of the device. There is. In this case, the control unit 80 controls the device to make an emergency stop when the pressure detected by the pressure sensor 62P exceeds a predetermined value.

(2) Even when the emergency stop of (1) does not occur, when the pump 63 is started, the flow rate of the first permeated water is controlled to the pump 61 within a predetermined range. In this case, the amount of the first permeated water is insufficient. In this case, the pressure sensor 62P detects a negative pressure, and the control unit 80 may stop the RO unit 60 in an emergency to avoid damage to the device due to negative pressure cavitation. In this case, when the pressure detected by the pressure sensor 62P is less than the predetermined positive pressure, the control unit 80 controls the device to make an emergency stop.

(3) Further, the flow rates of the first concentrated water and the second concentrated water may change due to the secular change of the reverse osmosis membrane and the water temperature change of the water to be treated. Therefore, even when trying to adjust this flow rate to a predetermined flow rate, the above phenomena (1) and (2) may occur. Therefore, it is necessary to pay close attention to the work of adjusting the flow rate, which makes operation management more difficult.

The problems of (1) to (3) are that the flow rate of the first permeated water that has passed through the RO device 62 through the pump 61 is preset when the RO device has a multi-stage configuration without storing the intermediate tank or the like. This is a phenomenon that occurs in order to control the temperature within a specified range.
Therefore, in the present embodiment, the pump 61 is controlled so that the pressure of the first permeated water that has permeated the RO device 62 falls within a predetermined range. In this case, in the case of the above (1), when the pressure of the first permeated water rises, the pump 61 controls to reduce the amount of water to be fed to the RO device 62, and The pressure of the permeate water will not be excessive. Further, in the case of (2), in order to prevent the pressure of the first permeated water from decreasing, the pump 61 controls to feed more treated water to the RO device 62, so that the inlet of the pump 63 is The positive pressure is maintained and the device can continue to operate. Similarly, the problem (3) is less likely to occur.

Next, the operation of the purified water production unit 1 will be described.
FIG. 3 is a flowchart explaining the operation of the purified water manufacturing unit 1.
Hereinafter, the operation of the purified water production unit 1 will be described with reference to FIGS.

First, the water to be treated is introduced into the raw water tank 20 and is temporarily stored in the raw water tank 20 (step 101).

Then, it is determined whether the activated carbon tower 40 or the like needs to be sterilized (step 102). The timing of sterilization can be determined by the water flow time and the water flow rate. When it is necessary to sterilize (Yes in step 102), the water to be treated is converted into hot water by the warming device 30 by the pump P1 and supplied, and sterilization is performed (step 103). After sterilization, the process returns to step 101.

On the other hand, when it is not necessary to sterilize (No in step 102), the warming device 30 heats it to a certain temperature and sends it to the activated carbon tower 40 (step 104).
Then, free chlorine in the water to be treated is removed by the activated carbon tower 40 in the water to be treated (step 105: free chlorine removing step). Further, fine particles in the water to be treated are removed by the prefilter 50 (step 106).

Next, the RO unit 60 purifies the water to be treated.
At this time, the control unit 80 controls the pump 61 so that the pressure of the first permeated water that has permeated the RO device 62 falls within a predetermined range (step 107: first delivery step). As a result, the water to be treated permeates the RO device 62 and is filtered by the reverse osmosis membrane (step 108: first filtration step).
Further, the control unit 80 controls the pump 63 so that the flow rate of the second permeated water that has permeated the RO device 64 is within a predetermined range (step 109: second delivery step). As a result, the water to be treated permeates the RO device 64 and is filtered by the reverse osmosis membrane (step 110: second filtration step).

The water that has passed through the RO unit 60 is stored in the storage tank 70 as pharmaceutical purified water (step 111).

In the purified water production unit 1 described in detail above, an example in which an RO device using a reverse osmosis membrane is used as the filtering means has been described, but the present invention is not limited to this and is particularly limited as long as it has a filtering function. Not a thing. For example, a UF (Ultrafiltration Membrane) device using an ultrafiltration membrane may be used.

Further, in the purified water production unit 1 described above in detail, the RO unit 60 is used as a device for purifying the water to be treated. For example, an EDI (Electrodeionization: continuous electric regeneration type pure water device) unit is provided after the RO unit 60. May be used in combination with other devices.
In addition, a deaeration membrane, a safety filter, or the like may be provided between the filtration means such as the RO device of the RO unit 60.

Further, in the above-described example, the control is performed to send the water to the final-stage RO device so that the flow rate of the permeated water is within the predetermined range, but this is not essential. In other words, if control is performed so that the pressure of the permeated water is set to fall within a predetermined range for the RO devices other than the final stage, the water flow is stabilized, and the RO devices at the final stage are Control may not be needed.

Furthermore, in the above-mentioned example, the RO unit 60 was used for the production of purified drug water, but the present invention is not limited to this. For example, it can be used for producing pure water or desalinating seawater.

Hereinafter, the present invention will be described in more detail with reference to examples, but the present invention is not limited to these examples as long as the gist thereof is not exceeded.

(Example 1)
In this embodiment, the purified water production unit 1 shown in FIGS. 1 and 2(a) was used.
Of these, NTR-759HR manufactured by Nitto Denko Corporation was used as the reverse osmosis membrane of the RO device 62 of the RO unit 60. It comprises a spiral type 8 inch synthetic composite membrane. And 20 pieces of this were used, and four pieces were filled into 5 FRP vessels. Of these, 3 vessels were configured as a 1st bank and 2 vessels were configured as a 2st bank.
An inverter-controlled pump was prepared as the pump 61. It has a capacity of 25.8 m ^{3 /} h×130 mH×18.5 kW.

Further, as the reverse osmosis membrane of the RO device 64, NTR-759HR manufactured by Nitto Denko Corporation was used in the same manner. Then, 16 pieces of this were used, and four pieces were filled in four FRP vessels. Of these, 3 vessels were configured as a 1st bank and 1 vessel was configured as a 2st bank.
An inverter-controlled pump was prepared as the pump 63. It has a capacity of 16.6 m ³ /h×137 mH×11 kW.

A degassing membrane (X50·10″×28″) manufactured by Polypore Co., Ltd. was provided between the RO device 62 and the RO device 64.

Then, the control unit 80 controls the pump 61 so that the pressure of the first permeated water becomes 0.25 MPa, and controls the pump 63 so that the flow rate of the second permeated water becomes 13.9 m ³ /h. ..

As a result, the emergency stop of the RO unit 60 did not occur even under various operating conditions. In other words, stable operation could be performed even after the deterioration of the reverse osmosis membrane over time, such as when the device was started up, when the flow rates of the first concentrated water and the second concentrated water were adjusted, when the temperature of the water to be treated changed. .. The power consumption of the pump 61 was about 81% of the rating, the power consumption of the pump 63 was about 77% of the rating, and the amount of power consumption was smaller.

(Comparative Example 1)
The pump 61 was controlled in the same manner as in Example 1 except that the flow rate of the first permeated water was controlled to be 13.9 m ³ /h and an intermediate tank was provided between the RO device 62 and the RO device 64. The RO unit 60 was operated.
By providing the intermediate tank, the emergency stop at the time of starting the equipment did not occur. However, the space for installing the intermediate tank and the installation cost were required separately. Since the intermediate tank is prone to bacterial proliferation, it was necessary to make it of stainless steel, to provide an immersion type ultraviolet sterilizer inside, and to install a sterilizing filter at the vent of the intermediate tank. Therefore, the installation cost of the intermediate tank was further increased. In addition, the pressure of the first permeated water discharged from the RO device 62 becomes unavailable due to the installation of the intermediate tank, so that the power required for the pump 63 increases and the power consumption increases as compared with the first embodiment.

DESCRIPTION OF SYMBOLS 1... Purified water manufacturing unit, 20... Raw water tank, 30... Heating device, 40... Activated carbon tower, 50... Prefilter, 60... RO unit, 61, 63... Pump, 62, 64... RO device, 70... Storage tank , 80... Control unit

Claims (5)

Three or more filtering means that allow the water to be treated or the permeated water to permeate through the filtration membrane without being stored midway;
The pressure of the permeated water is provided within a predetermined range for each of the three or more filtering means provided in the preceding stage and excluding the final stage filtering means of the three or more filtering means. And three or more delivery means for delivering water so that the flow rate of permeated water is within a predetermined range with respect to the final stage filtration means,
A filtering device comprising: A first filtering means for purifying the water to be treated through a filtration membrane;
Second filtering means for further refining the first permeated water that has passed through the first filtering means without passing through the filtration membrane, and
Third filtering means for further refining the second permeated water that has passed through the second filtering means without passing through the filtration membrane, and
First delivery means for delivering water to be treated to the first filtration means;
Second delivery means for delivering the first permeate to the second filtration means;
Third delivery means for delivering the second permeate to the third filtration means,
The pressure of the first permeated water in the first delivery means is set within a predetermined range, and the third permeated water that has passed through the third filtration means is passed through the third delivery means. Control means for keeping the flow rate within a predetermined range,
A filtering device comprising: A medical purified water production apparatus for purifying treated water to produce purified water which is pharmaceutical water,
A free chlorine removal unit that removes free chlorine in the water to be treated,
A filtering unit for filtering the water to be treated,
Equipped with
The filtration unit is
A first filtering means for purifying the water to be treated through a filtration membrane;
Second filtering means for further refining the first permeated water that has passed through the first filtering means without passing through the filtration membrane, and
Third filtering means for further refining the second permeated water that has passed through the second filtering means without passing through the filtration membrane, and
First delivery means for delivering water to be treated to the first filtration means;
Second delivery means for delivering the first permeate to the second filtration means;
Third delivery means for delivering the second permeate to the third filtration means,
The pressure of the first permeated water in the first delivery means is set within a predetermined range, and the third permeated water that has passed through the third filtration means is passed through the third delivery means. Control means for keeping the flow rate within a predetermined range,
An apparatus for producing purified water for medicine, comprising: The said 1st filtration means and the said 2nd filtration means perform filtration using a reverse osmosis membrane, The refined|purified water manufacturing apparatus of Claim 3 characterized by the above-mentioned. A method for producing purified water for medical treatment, which comprises purifying treated water to produce purified water which is water for pharmaceutical use,
A free chlorine removing step of removing free chlorine in the water to be treated,
A first filtration step of permeating the water to be treated through a first filtration means having a filtration membrane;
A second filtration step of allowing the second filtration means having a filtration membrane to permeate the first permeated water that has permeated the first filtration means without storing it;
A third filtration step of allowing the second permeated water that has permeated through the second filtration means to pass through the third filtration means provided with a filtration membrane without storing it;
A first delivery means for delivering the treated water to the first filtering means using the first delivery means for delivering the treated water so that the pressure of the first permeated water is within a predetermined range. And the delivery process of
The third delivery means for delivering the second permeated water to the third filtration means is used, and the flow rate of the third permeated water that has passed through the third filtration means is within a predetermined range. And a third delivery step of delivering the second permeate,
A method for producing purified pharmaceutical water, which comprises:

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