JP6629216B2 - 上気道感染症の治療のためのポリイノシン酸−ポリシチジル酸（ポリ（ｉ：ｃ））製剤 - Google Patents

上気道感染症の治療のためのポリイノシン酸−ポリシチジル酸（ポリ（ｉ：ｃ））製剤 Download PDF

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JP6629216B2
JP6629216B2 JP2016551030A JP2016551030A JP6629216B2 JP 6629216 B2 JP6629216 B2 JP 6629216B2 JP 2016551030 A JP2016551030 A JP 2016551030A JP 2016551030 A JP2016551030 A JP 2016551030A JP 6629216 B2 JP6629216 B2 JP 6629216B2
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acid
pea starch
microparticles
microparticle
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JP2016535094A (ja
JP2016535094A5 (enExample
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マリオ ルドウィック キリンジェレス，ディディラー
マリオ ルドウィック キリンジェレス，ディディラー
ディジック，アレックス アンリ バン
ディジック，アレックス アンリ バン
メンシチ，ユルゲン
アルバート マルコム ブルース
アルバート マルコム ブルース
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ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2016551030A 2013-11-06 2014-11-05 上気道感染症の治療のためのポリイノシン酸−ポリシチジル酸（ポリ（ｉ：ｃ））製剤 Expired - Fee Related JP6629216B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13191742.9 2013-11-06
EP13191742 2013-11-06
PCT/EP2014/073762 WO2015067632A1 (en) 2013-11-06 2014-11-05 Polylnosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections

Publications (3)

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JP2016535094A JP2016535094A (ja) 2016-11-10
JP2016535094A5 JP2016535094A5 (enExample) 2017-12-14
JP6629216B2 true JP6629216B2 (ja) 2020-01-15

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JP2016551030A Expired - Fee Related JP6629216B2 (ja) 2013-11-06 2014-11-05 上気道感染症の治療のためのポリイノシン酸−ポリシチジル酸（ポリ（ｉ：ｃ））製剤

Country Status (11)

Country Link
US (1) US20160271165A1 (enExample)
EP (1) EP3065714B1 (enExample)
JP (1) JP6629216B2 (enExample)
KR (1) KR20160072140A (enExample)
CN (1) CN105939709A (enExample)
AU (1) AU2014345667A1 (enExample)
CA (1) CA2929142A1 (enExample)
IL (1) IL245412A0 (enExample)
MX (1) MX2016005883A (enExample)
RU (1) RU2016117398A (enExample)
WO (1) WO2015067632A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018515530A (ja) * 2015-05-11 2018-06-14 ヤンセン・サイエンシズ・アイルランド・ユーシー 上気道感染症の予防および／または治療のためのポリイノシン酸−ポリシチジル酸（ポリ（ｉ：ｃ））のエンドウマメデンプン製剤

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201406208QA (en) 2012-05-03 2014-11-27 Janssen Sciences Ireland Uc Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections
PT3319587T (pt) 2015-11-17 2019-11-20 Bioncotech Therapeutics S L Nova composição farmacêutica que compreende partículas compreendendo um complexo de um polirribonuleótido de cadeia dupla e uma polialquilenoimina
US20200060972A1 (en) 2016-11-16 2020-02-27 Janssen Sciences Ireland Unlimited Company Formulations of polyinosinic acid and polycytidylic acid for the prevention of upper respiratory tract infections
JP2020520368A (ja) * 2017-05-17 2020-07-09 ビオンコテック セラピューティクス エセ．エレ 二本鎖ポリリボヌクレオチドとポリアルキレンイミンとの複合体を含む粒子を含む新規な医薬組成物
KR102123489B1 (ko) 2020-03-13 2020-06-16 주식회사 휴먼셀바이오 자연살해세포 배양액 조성물 및 이를 이용한 자연살해세포 배양방법
US20230338395A1 (en) 2020-04-19 2023-10-26 Ludwig Englmeier Prophylaxis and treatment of coronavirus infection
CN118680868B (zh) * 2023-03-24 2026-04-17 清华大学 一种核酸药物递送系统及其制备和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5707644A (en) * 1989-11-04 1998-01-13 Danbiosyst Uk Limited Small particle compositions for intranasal drug delivery
CN101229378A (zh) * 2005-05-05 2008-07-30 国家淀粉及化学投资控股公司 用于送递活性剂的组合物
US20070166239A1 (en) * 2006-01-13 2007-07-19 Haixiang Lin Mucosal immunogenic substances comprising a polyinosinic acid - polycytidilic acid based adjuvant
CN101491503A (zh) * 2008-12-17 2009-07-29 天津瑞普生物技术股份有限公司 一种用于宠物的聚肌胞滴丸及其制备方法
CN101757018A (zh) * 2008-12-24 2010-06-30 天津瑞普生物技术股份有限公司 一种用于畜禽的聚肌胞干粉及其制备方法
CN102488703A (zh) * 2011-12-15 2012-06-13 天津济命生生物科技有限公司 一种聚肌胞制剂的制备方法和抗肿瘤的用途
SG11201406208QA (en) * 2012-05-03 2014-11-27 Janssen Sciences Ireland Uc Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018515530A (ja) * 2015-05-11 2018-06-14 ヤンセン・サイエンシズ・アイルランド・ユーシー 上気道感染症の予防および／または治療のためのポリイノシン酸−ポリシチジル酸（ポリ（ｉ：ｃ））のエンドウマメデンプン製剤

Also Published As

Publication number Publication date
JP2016535094A (ja) 2016-11-10
WO2015067632A1 (en) 2015-05-14
US20160271165A1 (en) 2016-09-22
AU2014345667A1 (en) 2016-05-19
EP3065714B1 (en) 2020-02-12
EP3065714A1 (en) 2016-09-14
CN105939709A (zh) 2016-09-14
CA2929142A1 (en) 2015-05-14
KR20160072140A (ko) 2016-06-22
MX2016005883A (es) 2016-08-17
RU2016117398A3 (enExample) 2018-08-22
RU2016117398A (ru) 2017-12-11
IL245412A0 (en) 2016-06-30

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